Suchergebnisse

Hair Analysis in Clinical and Forensic Toxicology is an essential reference for toxicologists working with, and researching, hair analysis. The text presents a review of the most up-to-date analytical methods in toxicological hair analysis, along with state-of-the-art developments in the areas of hair physiology, sampling, and pre-treatments, as well as discussions of fundamental issues, applications, and results interpretation. Topics addressed include the diagnosis of chronic excessive alcohol drinking by means of ethyl glucuronide (EtG) and fatty acid ethyl esters (FAEE), the early detection of new psychoactive substances, including designer drugs, the development of novel approaches to screening tests based on mass spectrometry, and the detection of prenatal exposure to psychoactive substances from the analysis of newborn hair

This book examines the most recent advances in the toxicology of pesticides. An initial series of chapters deals with various aspects of experimental toxicology. Assessment of human exposure, clinical management of pesticide poisoning, individual susceptibility to pesticide toxicity and extrapolation of animal data to human are also discussed. Furthermore, the problems of the environmental distribution, fate, ecotoxicology, as well as risk management of pesticides are discussed. This book should prove useful in improving the relationship between experimental toxicologists and clinicians, and will facilitate the process of risk assessment and risk management

Humans exposed to neurotoxins may exhibit alterations in cognitive and affective functioning and report a wide range of subjective symptoms. The multidisciplinary field of "neuropsychological toxicology" provides a framework for the systematic assessment and interpretation of adverse effects. Neuropsychological assessment is of interest not only to clinicians, but also to regulatory and legislative authorities. The importance of neuropsychological toxicology in the area of occupational risk research is increasingly being recognized. Possible fields of application include behavioral monitoring for preventive purposes, expert assessment in the context of compensation cases, and treatment in rehabilitation programs. This article reviews common research approaches, selected findings, and methodological problems of this emerging discipline and summarizes the implications for related fields of psychological research.

New data continually indicate that antioxidants may contribute to reductions in cancer risks and that chronic consumption of low levels of chemical carcinogens in our diet may contribute to an increased risk of developing specific types of cancers. Research also shows that in America today, the leading causes of death are cancer and heart disease. Considering that diet plays a significant role in the development of both of these diseases, issues of food toxicology become particularly topical

Environmental toxicology is one of the most interdisciplinary sciences. Biologists, microbiologists, chemists, engineers, environmentalists, ecologists and other scientists work together in this new scientific discipline. Assessment of the environmental effects of chemicals is complicated as it depends on the organisms tested and involves not only the toxicity of individual chemicals, but also their interactive effects (including antagonistic and synergistic ones), and genotoxicity, mutagenicity and immunotoxicity testing. Hazardous waste management is closely related to environmental toxicology and there is a growing need for techniques and practices to minimize the environmental effects of chemicals.This volume contains the contributions presented at the 2nd Conference on Environmental Toxicology, which was held in Granada, Spain in 2008. The papers cover the following subject areas: Risk Assessment; Human Health Risk; Effluent Toxicity; Bioaccumulation of Chemicals; Biodegredation and Bioremediation; Biological Effects Monitoring; Laboratory Tests and Validation; Ecotoxicity of Emerging Chemicals; New Trends in Environmental Toxicology

Human pharmaceutical products / Shayne C. Gad -- Animal health products / Elizabeth Roberts -- Regulatory aspects and strategy in medical device and bio materials safety evaluation / Shayne C. Gad -- Food additives & nutrition supplements / Chada S Reddy, A. Wallace Hayes -- Regulations affecting cosmetic and personal care products / Bennett Varsho, George DeGeorge -- OTC drugs and nutraceuticals / Charles B. Spainhour -- Consumer products : nonpersonal care products regulatory review and labeling / Robert W. Kapp, Denese Deeds -- Agricultural chemicals : regulation, risk assessment, and risk management / Elliot Gordon -- Industrial chemicals : international regulation of new and existing chemicals (REACH, the new Toxic Substances Control Act and similar worldwide chemical control laws) / Sol Bobst -- Industrial chemicals : hazard communication, exposure limits, labeling and other workplace and transportation requirements under OSHA, DOT, and similar authorities around the world / Edward Sargent -- Federal air and water regulations : CAA, CWA, and SDWA / Alicia A. Taylor and M. Yusuf Khan -- Understanding the Safe Drinking Water and Toxic Enforcement Act of 1986 (California's Proposition 65) / Clint Skinner -- Safety data sheets / Dexter W.Sullivan, Jr -- GMOs (internationally) / Jack Budny -- Oversight regulations / Robin Guy