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Purpose of Study: One important aspect in regional development planning is to grow regional economies. It is expected to be a leverage and and attract other sectors to move and grow well. To develop the local economy, there are several things to be used as basis for regional development. The present aims to analyze the regional economic potentials in the development of superior markets of a nation. Methodology: Exploratory research method is used in the present study to obtain more in-depth results that can be developed according to the outcomes of the analysis. It has been carried out by determining the selection of one of the district's superior products. By using the endogenous development strategy paradigm and integrating endowment factors with human resources capabilities, the development and growth of Bondowoso Regency will be more directed, clear, measurable and targeted. In an effort to realize the development of new economic growth centers in undeveloped areas, determining superior products is very important. Furthermore, by encouraging the development of the specific potential of underdeveloped regions, it is expected to be able to encourage and accelerate economic growth and improve community welfare. so that this builds a new center for economic growth. In general, the flagship program of each district is used as leverage in stimulating regions for development. Notably, there are six parameters left behind. These include the community economy, human resources, infrastructure (infrastructure), local financial capacity (fiscal gap), accessibility, and regional characteristics. It is expected that poverty alleviation and unemployment reduction can be achieved through an increase in the local financial capacity through optimization of the potential of local products. The development of district superior product programs in growth node will be beneficial in encouraging the economic growth of the community. Main Findings: The results of this study shortlisted some superior agricultural products in the regency with a corn LQ value of 3.86, 4.28 rice; chili 2.37; and cassava 3.92. The coconut plantation 1.89; betel 1.59 and sugar cane 3.31. For the livestock sector, the LQ of Cattle was 3.91; Goat 3.02 and free-range chicken 2.98. From the results of the discussion and in-depth analysis, the flagship products of Bondowoso district were rice, sugar cane, cattle and corn. Implications/Applications: The present research is expected to establish local products that represent regional superior commodities and can be produced to improve the economy of the community. Such development will also provide job opportunities for the local communities and reduce the rate of poverty. Furthermore, it provides avenues for channeling government funding in terms of aid to provide an impetus for stimulating growth and jobs.