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Article(electronic)#2January 1990
Early prediction and prevention of child abuse
In: Child abuse & neglect: the international journal ; official journal of the International Society for the Prevention of Child Abuse and Neglect, Volume 14, Issue 1, p. 137-138
ISSN: 1873-7757
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Article(electronic)#3January 1987
Sixth international congress on child abuse and neglect, Sydney, Australia, August 11–14, 1986
In: Child abuse & neglect: the international journal ; official journal of the International Society for the Prevention of Child Abuse and Neglect, Volume 11, Issue 1, p. 3-5
ISSN: 1873-7757
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Article(electronic)#4July 2, 2020
Resident perspectives on local food system performance and development priorities: A pilot analysis of the local food vitality index
In: Local development & society, Volume 1, Issue 2, p. 116-139
ISSN: 2688-3600
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Article(electronic)#5January 1982
"Montrose" child life protection unit: A treatment and assessment model in child abuse intervention
In: Child abuse & neglect: the international journal ; official journal of the International Society for the Prevention of Child Abuse and Neglect, Volume 6, Issue 4, p. 389-394
ISSN: 1873-7757
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Article(electronic)#6January 2010
An ex post analysis as a followup to stated preferences for management strategies in Nevada's Black Rock Desert
In: Annals of leisure research: the journal of the Australian and New Zealand Association of Leisure Studies, Volume 13, Issue 4, p. 630-651
ISSN: 2159-6816
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Article(electronic)#7
Adverse Selection in the Group Life Insurance Market
In: IZA Discussion Paper No. 14985
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Article(electronic)#9
Hospital Closures and Short-Run Change in Ambulance Call Times
In: IZA Discussion Paper No. 12797
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Open Access#102022
Symptom burden and quality of life with chemotherapy for recurrent ovarian cancer : the Gynecologic Cancer InterGroup-Symptom Benefit Study
Lee, Yeh Chen; King, Madeleine T; OConnell, Rachel L; Lanceley, Anne; Joly, Florence; Hilpert, Felix; Davis, Alison; Roncolato, Felicia T
Lee, Yeh Chen; King, Madeleine T; OConnell, Rachel L; Lanceley, Anne; Joly, Florence; Hilpert, Felix; Davis, Alison; Roncolato, Felicia T; Okamoto, Aikou; Bryce, Jane; Donnellan, Paul; Oza, Amit M; Åvall Lundqvist, Elisabeth; Berek, Jonathan S; Ledermann, Jonathan A; Berton, Dominique; Sehouli, Jalid; Feeney, Amanda; Kaminsky, Marie-Christine; Diamante, Katrina; Stockler, Martin R; Friedlander, Michael L
Objective The Gynecologic Cancer InterGroup (GCIG)-Symptom Benefit Study was designed to evaluate the effects of chemotherapy on symptoms and health-related quality of life (HRQL) in women having chemotherapy for platinum resistant/refractory recurrent ovarian cancer (PRR-ROC) and potentially platinum sensitive with >= 3 lines of chemotherapy (PPS-ROC >= 3). Methods Participants completed the Measure of Ovarian Cancer Symptoms and Treatment (MOST) and European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire QLQ-C30 questionnaires at baseline and every 3-4 weeks until progression. Participants were classified symptomatic if they rated >= 4 of 10 in at least one-third of symptoms in the MOST index. Improvement in MOST was defined as two consecutive scores of = 10 points above baseline in the QLQ-C30 summary score scale (range 0-100). Results Of 948 participants enrolled, 910 (96%) completed baseline questionnaires: 546 with PRR-ROC and 364 with PPS-ROC >= 3. The proportions of participants symptomatic at baseline as per MOST indexes were: abdominal 54%, psychological 53%, and disease- or treatment-related 35%. Improvement was reported in MOST indexes: abdominal 40%, psychological 35%, and disease- or treatment-related 38%. Median time to improvement in abdominal symptoms occurred earlier for PRR-ROC than for PPS-ROC >= 3 (4 vs 6 weeks, p=0.044); median duration of improvement was also similar (9.0 vs 11.7 weeks, p=0.65). Progression-free survival was longer among those with improvement in abdominal symptoms than in those without (median 7.2 vs 2.5 months, p= 3 (p=0.29), and 102/481 (21%) of those with abdominal symptoms at baseline. Conclusion Over 50% of participants reported abdominal and psychological symptoms at baseline. Of those, 40% reported an improvement within 2 months of starting chemotherapy. Approximately one in six participants reported an improvement in HRQL. Symptom monitoring and supportive care is important as chemotherapy palliated less than half of symptomatic participants. ; Funding Agencies|NHMRCNational Health and Medical Research Council of Australia [1063012, 570893]; Target Ovarian Cancer [UCL-P001AL]; Cancer Research UKCancer Research UK; UCL Cancer Trials Centre [C444/A15953]; Australian Government through Cancer AustraliaAustralian Government; NHMRC Program grantNational Health and Medical Research Council of Australia; Department of HealthEuropean Commission
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