La incidencia de cáncer esofágico en Estados Unidos de Norteamérica y otros países del mundo se ha incrementado en los últimos años. Dado que el resultado obtenido en la detección temprana y tratamiento del cáncer esofágico no ha sido satisfactoria, recientes investigaciones se han enfocado en técnicas de biología molecular, medicina nuclear, terapia fotodinámica y cirugía de mínima invasión.
Stingless bees (meliponines) play an important role in ecosystems; they pollinate different plant species, assist in the reproduction and conservation of floral biodiversity and their products can be obtained and sold, with the consequent economic benefit for stingless beekeepers. Surveys were conducted to find out how much knowledge inhabitants of two marginalized communities of the Manantlan Sierra in Jalisco, Mexico, have on the use and exploitation of stingless bees. In addition, several stingless bee species of this region were captured and identified, and wild nests of those bees were located and recorded in their natural habitats. Information about the knowledge and culture of stingless bees in the region was analyzed and based on that as well as on the most abundant species captured, those with more potential are suggested for management in a sustainable manner. Unlike other areas of Mexico where meliponiculture is practiced, in Jalisco there is no record of traditional culture of meliponines. However, a certain level of knowledge and a high degree of interest was found among the respondents for engaging in keeping and managing stingless bees, mainly because their management does not involve the risk of stinging incidents. Nine stingless bee species were identified in total. Of these, the most abundant were Scaptotrigona hellwegeri, Trigona fulviventris, Partomona bilineata, Friseomelita nigra and Nannotrigona perilampoides. It is recommended that studies are conducted to develop management practices for these bee species. The implementation of courses on how to keep these meliponines is also recommended, so that in the future, the inhabitants of these communities can benefit from the integral and sustainable use of stingless bees.
Estamos aquí reunidos para honrar la memoria de un colega, de un amigo que ya no está más entre nosotros. Cada vez que esto ocurre queda en nosotros la sensación de que algo nos falta, que ya no estamos completos. A todos nos sorprendió y dolió la muerte de Crescencio, a quien aprendimos a apreciar en sus diversas facetas y en los distintos aspectos de su personalidad. Su ausencia es motivo de este homenaje.
Gallocanta lagoon, NE Spain, is one of the main stopover and wintering areas of Common Cranes (Grus grus) migrating through Western Europe. We investigated how the water level of the lagoon where cranes roost, precipitation, and air temperature might have influenced the species' migration and wintering patterns in this area between 1973 and 2018. Over the study period, the mean annual air temperature increased at 0.3 °C per decade. Simultaneously, cranes advanced the spring peak migration date at a rate of 0.37 days/year. Water level and rainfall during spring were also positively correlated with the date of spring migration peak. Because cranes need shallow water to roost, and must drink water from streams because the lagoon is saline, these correlations suggest that low water levels at roosting sites and drinking water shortage may have further accelerated the onset of northward spring migration. The water level was also positively correlated with peak crane numbers in autumn, suggesting that the roosting capacity of the lagoon may limit numbers of cranes that can stopover in the area. We conclude that global warming, variations in the water level of the lagoon, and precipitation during spring have determined changes in the use of Gallocanta as a staging and wintering area by Common Cranes during the last decades. Because climatic models predict further decreases in rainfall and higher temperatures in the area, further advances in the migration phenology of cranes should be expected, which might also have implications for the conservation and management of the species and the study area. ; project AgroSOS (CGL2015-66016-R Spanish Ministry of Economy and Competitiveness - FEDER funds [EU]) ; Government of Aragón (Spain) through a predoctoral internship to J. M. Orellana (BOA 20/07/2017) ; Peer reviewed
A reliable estimate of the wind potential in the marine atmospheric boundary layer (MABL) is of great importance to justify the energetic viability of new offshore wind farms. The purpose of the study is to provide an additional tool for the prediction of the energy that a wind turbine would produces in the open sea from the usual way of measurements at sea, that is, when they are carried out with measuring masts, where the meteorological data are obtained at levels much lower than those of a wind turbine hub. For this, the variation in the wind speed with the height in the MABL is determined, based on the Monin–Obukhov similarity theory, according to the boundary conditions of the air–sea interface, where the input data for the Validation of the results are extracted from the German FINO 3 research platform during the years 2016, 2017, and 2018. It is applied to the production of electrical energy from a 6.0 MW commercial wind turbine, with the hub at 100 m above the sea surface. As a more prominent result, the deviations from the proposed method do not exceed 2.5% in the energy calculation ; To the Bundesministerium für Wirtschaft und Energie (BMWi) and Projektträger Jülich (PTJ), both of the Government of Germany, for facilitating the use of data of the FINO Project. To Siemens Gamesa Renewable Energy, for the use of the characteristic curves of the SWT-6.0-154 wind turbine
Abstract. We detail a new prediction-oriented procedure aimed at volcanic hazard assessment based on geophysical mass flow models constrained with heterogeneous and poorly defined data. Our method relies on an itemized application of the empirical falsification principle over an arbitrarily wide envelope of possible input conditions. We thus provide a first step towards a objective and partially automated experimental design construction. In particular, instead of fully calibrating model inputs on past observations, we create and explore more general requirements of consistency, and then we separately use each piece of empirical data to remove those input values that are not compatible with it. Hence, partial solutions are defined to the inverse problem. This has several advantages compared to a traditionally posed inverse problem: (i) the potentially nonempty inverse images of partial solutions of multiple possible forward models characterize the solutions to the inverse problem; (ii) the partial solutions can provide hazard estimates under weaker constraints, potentially including extreme cases that are important for hazard analysis; (iii) if multiple models are applicable, specific performance scores against each piece of empirical information can be calculated. We apply our procedure to the case study of the Atenquique volcaniclastic debris flow, which occurred on the flanks of Nevado de Colima volcano (Mexico), 1955. We adopt and compare three depth-averaged models currently implemented in the TITAN2D solver, available from https://vhub.org (Version 4.0.0 – last access: 23 June 2016). The associated inverse problem is not well-posed if approached in a traditional way. We show that our procedure can extract valuable information for hazard assessment, allowing the exploration of the impact of synthetic flows that are similar to those that occurred in the past but different in plausible ways. The implementation of multiple models is thus a crucial aspect of our approach, as they can allow the covering of other plausible flows. We also observe that model selection is inherently linked to the inversion problem.
Microbial quality of rainbow trout surface tissue (Oncorhynchus mykiss) and production ponds water where it is produced in northwestern Chihuahua state, Mexico, was assessed in trouts (200 fishes) and water (260 sampling) from nine fast stream, thirteen concrete and six dirt fish ponds during summer and winter seasons. Microbial quality was determined by measuring aerobic mesophiles, total coliform count, faecal coliforms and Salmonella spp., samples from the deep washing of the fish surface and the ponds. Temperature and oxygen content of water were also measured. The results for trout washing water indicated only significant differences (P<0.05) for aerobic mesophiles between seasons (398.11 CFU/mL in winter and 19,489.45 CFU/mL in summer), Salmonella spp. was not present in any fish or pond water samples. Aerobic mesophiles showed also higher numbers in water for summer season at water entrance, middle and discharge points of the different fish production ponds. Water temperature and oxygen content were always inside the normal range values considered for trout production in the three types of ponds, but water oxygen content showed significant difference (P<0.05) between the fast stream and dirt pond systems. It can be concluded, from the results obtained that surface tissue of the trout produced in the studied mexican northwestern Chihuahua State, ponds has excellent quality, having very low microbial counts and that water discharged from the production systems evaluated do not deteriorate the ecosystems, according to the government present regulations. ; Con el objetivo de caracterizar la calidad microbiológica del cultivo de la trucha arco iris (Oncorhynchusmykiss) (200 peces) y del agua de producción (260 muestras) de la misma, se muestrearon en la región noroeste del Estado de Chihuahua, 9 granjas con sistema de producción de corriente rápida, 13 con sistema de concreto y 6 con sistema rústico, en dos épocas del año (invierno y verano). Se determinaron de la superficie de los pescados y del agua: ...
El trasplante cardiopulmonar se ha transformado en una modalidad terapéutica bien aceptada para pacientes con enfermedad cardiaca y pulmonar en estado terminal. El refinamiento en los criterios del donador y sus cuidados, la selección del receptor incluyendo en forma importante la consideración de los aspectos psicológicos, la terapia inmunosupresora, diagnóstico oportuno y el tratamiento del rechazo así como un entendimiento más preciso de las complicaciones a largo plazo, han mejorado los resultados en el trasplante de corazón y pulmón, con una sobrevida actual a un año del 85% y 70%, respectivamente.
Abstract Objetivo: Demostrar que el uso de programas y clínicas especializadas son útiles para ayudar a pacientes con enfermedades crónicas. Material y métodos: Se lograron implementar 9 consultorios de atención médica de la siguiente forma, 2 de Endocrinología, 3 consultorios de Clínica de Enfermedades Crónicas, uno de educación en diabetes e hipertensión, así como 3 de apoyo nutricional. Se midió valores absolutos del número de consultas durante los años 2017, 2018, 2019 y parte del 2020. Resultados y discusión: Estos modelos no solo son un beneficio para los pacientes, médicos generales tanto militares como profesionales de la salud civiles son capacitados para enfrentar estos padecimientos prevalentes en nuestro país.
https://3dbionotes.cnb.csic.es/ws/covid19 ; The web platform 3DBionotes-WS integrates multiple Web Services and an interactive Web Viewer to provide a unified environment in which biological annotations can be analyzed in their structural context. Since the COVID-19 outbreak, new structural data from many viral proteins have been provided at a very fast pace. This effort includes many cryogenic Electron Microscopy (cryo-EM) studies, together with more traditional ones (X-rays, NMR), using several modeling approaches and complemented with structural predictions. At the same time, a plethora of new genomics and interactomics information (including fragment screening and structure-based virtual screening efforts) have been made available from different servers. In this context we have developed 3DBionotes-COVID-19 as an answer to: (1) The need to explore multi-omics data in a unified context with a special focus on structural information and (2) the drive to incorporate quality measurements, especially in the form of advanced validation metrics for cryogenic Electron Microscopy. ; We acknowledge financial support from: CSIC (PIE/COVID-19 number 202020E079), the Comunidad de Madrid through grant CAM (S2017/BMD-3817), the Spanish Ministry of Science and Innovation through projects (SEV 2017-0712, FPU-2015/264, PID2019-104757RB-I00 / AEI / 10.13039/501100011033), the Instituto de Salud Carlos III: PT17/0009/0010 (ISCIII-SGEFI / ERDF-) and the European Union and Horizon 2020 through grant: CORBEL (INFRADEV-01-2014- 1, Proposal 654248) and EOSC Life (INFRAEOSC-04-2018, Proposal: 824087). This work was supported by Instruct-ULTRA (Grant 731005), an EU H2020 project to further develop the services of Instruct-ERIC. Contributions from the Coronavirus Structural Task Force were supported by the German Federal Ministry of Education and Research [grant no. 05K19WWA] and Deutsche Forschungsgemeinschaft [project TH2135/2-1]. The authors acknowledge the support and the use of resources of Instruct, a Landmark ESFRI project. ; Peer reviewed
Este artículo realiza un breve análisis referido al acceso a la información, la cual ha sido promovida por varios organismos internacionales de Derechos Humanos, para garantiza los derechos a la libertad de expresión el cual tiene un rol protagónico en el proceso democratizador, ya que permite que las personas conozcan el desempeño de las entidades públicas, fomentando la rendición de cuentas por parte de los funcionarios públicos sobre las decisiones que toman y con ello, una fiscalización ciudadana de la gestión pública. El acceso a la información es derecho que de cierta manera pasa a ser el corazón de la democracia, ya una ciudadanía que está bien informada sobre las intenciones y acciones de sus lídereselectos, puede contribuir de forma efectiva al proceso de toma de decisiones que afecta su futuro. En el sentido más básico, la participación democrática depende de la habilidad de los ciudadanos de acceder a la información que necesitan para tomar el control dentro de la sociedad. Cabe indicar que también existen restricciones, normas, leyes y reglamentos para el buen acceso de la información, la misma que debe ser protegida y resguardada tanto en el ámbito nacional como internacional.
