Open Access BASE2000

Reactive oxygen species and antioxidants in legume nodules

Abstract

28 Pags.- 2 Figs. the definitive version is available at: http://onlinelibrary.wiley.com/journal/10.1111/%28ISSN%291399-3054 ; Reactive oxygen species are a ubiquitous danger for aerobic organisms. This risk is especially elevated in legume root nodules due to the strongly reducing conditions, the high rates of respiration, the tendency of leghemoglobin to autoxidize, the abundance of nonprotein Fe and the presence of several redox proteins that leak electrons to O(2). Consequently, nodules are particularly rich in both quantity and diversity of antioxidant defenses. These include enzymes such as superoxide dismutase (EC 1.15.1.1) and ascorbate peroxidase (EC 1.11.1.11) and metabolites such as ascorbate and thiol tripeptides. Nodule antioxidants have been the subject of intensive molecular, biochemical and functional studies that are reviewed here. The emerging theme is that antioxidants are especially critical for the protection and optimal functioning of N(2) fixation. We hypothesize that this protection occurs at least at two levels: the O(2) diffusion barrier in the nodule parenchyma (inner cortex) and the infected cells in the central zone. ; Work in the laboratory of M. B. was supported by grants PB98-0522, 2FD97-1101 and HB98-163 from Dirección General de Enseñanza Superior e Investigación Científica, Comisión Interministerial de Ciencia y Tecnología, and the European Union. Work in the laboratory of D. A. D. was supported by National Science Foundation grants DCB-8903254, IBN-9206453 and IBN-9507491. ; Peer Reviewed

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