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La introducción de la Ilustración en España trajo consigo la decisión de la eliminar del Tribunal de la Inquisición por parte de los gobiernos de José y Napoleón Bonaparte en 1808; y Las Cortes de Cádiz, en 1813. Sin embargo las circunstancias que rodean a ambos procesos demuestran intenciones distintas a la hora de reducir la influencia religiosa en la política española ; The introduction of the Enlightenment in Spain brought the decision to eliminate the Court of the Inquisition by the governments of Joseph and Napoleon Bonaparte in 1808; and The Cadiz Cortes in 1813. However, the circumstances around both processes show different intentions about reducing religious influence in the Spanish politicy

Con esta investigación pretendemos poner de manifiesto la falta de conocimiento histórico conceptual que demuestran los alumnos del curso analizado y la falta de esta enseñanza en el currículo reflejado en la ausencia de ejercicios que ayuden a potenciar un aprendizaje significativo en los manuales escolares. El resultado es que los alumnos tienden a un aprendizaje memorístico que no le permite una comprensión de la relación entre el pasado y el presente. Proponemos la realización de una serie de ejercicios que preparan al alumno para que alcance conclusiones razonadas y entienda la evolución temporal del mundo contemporáneo, base del sistema político y social en el que viven ; In this research we want to show the lack of conceptual history knowledge that students demonstrate in the 4th degree at the high school and the lack of this teaching in the curriculum, reflected in the absence of exercises that help promote meaningful learning in school textbooks. The result is that students tend to rote learning that does not allow an understanding of the relationship between past and present. We suggest a series of exercises that prepare the student to reach reasoned conclusions and understand the evolution of the contemporary world, the basis of political and social system in which they live

[ES]La Revolución de las Comunidades de Castilla (1520-1521), en la que una serie de personalidades y nobleza de distintas ciudades se alzaron contra el modelo de Estado que trajo consigo el rey Carlos I, constituye un proceso histórico sobre el que hay mucho de erróneo y mitificado. Ello es fruto de que, durante el siglo XIX, en la construcción del Estado-nación español, numerosos políticos trataron de legitimar las nuevas ideas políticas liberales en este proceso. Así, construyeron un discurso que presentaba a los comuneros como supuestos luchadores por la libertad, contra el régimen absoluto de la Monarquía. En este trabajo realizamos una revisión de este proceso histórico, para la construcción de una unidad didáctica para la asignatura Historia de España de 2o de Bachillerato encaminada a su desmitificación entre el alumnado. Para ello proponemos una metodología didáctica fundamentalmente práctica, basada en el trabajo con diversas fuentes históricas y la posterior discusión de estas. Palabras clave Historia moderna, Carlos V, comuneros, liberalismo, didáctica, Bachillerato ; [EN]The aim of this work is to present a review of the historical process named as the Revolution of the Communities of Castile (1520-1521) as well as a didactic proposal for its teaching in a Secound Baccalaureate course of Spanish History. During this process, some personalities in addition to the nobility from different cities fought against the state model that was instituted by King Charles I of Spain. Many falsehoods and myths has appeared around this historical process: many politicians presented the commoners as supposed fighters against the absolutist monarchy in order to legalise the new liberal ideas in the Nineteenth Century. For this reason, we propose a teaching methodology fundamentally based on practical analysis, so students will work with various historical sources and the subsequent discussions generated about this topic. Our final goal is to demystify this historical process. Keywords Modern History, Charles V, commoners, liberalism, didactic, Baccalaureate.

Presented at the XXV International School of Theoretical Physics "Particles and Astrophysics - Standar Models and Beyond", Ustron, Poland, september 10-16, 2001. ; The origin and nature of ultrahigh-energy cosmic ray events, above the Greisen–Zatsepin–Kuzmin (GZK) cutoff energy, constitute a long-standing, unsolved mystery. Neutrinos are proposed candidates but their standard interactions with matter are too weak. In the context of a TeV-scale string theory, motivated by possible extra space dimensions, the neutrino–nucleon scattering is examined. Resonant string contributions increase substantially the standard model neutrino-nucleon cross section. Although they seem insufficient to explain the trans-GZK cosmic ray events, their effects might be detected in next experiments. ; Work supported by MCYT, Junta de Andalucía and the European Union under contracts FPA2000-1558, FQM101 and HPRN-CT-2000-00149, respectively.

Compared to partially premixed combustion (or combustion of non-homogeneous reactants in general), fully premixed and diffusion flames represent only two asymptotic limits of combustion modes. However, the deep knowledge accumulated over the years on these two elementary and archetypal flame prototypes is such that they remain the cornerstone and reference building blocks of most combustion modelling proposals. Therefore, from a general point of view, being able to distinguish between premixed and non-premixed modes of combustion thanks to a flame index appears as a quite appealing but challenging task that still concentrates many research efforts. Indeed, the availability of such an index is not only appealing to proceed with the analysis of either experimental or computational data issued from DNS (or highly resolved LES) databases. It is also an essential ingredient to elaborate advanced flamelet-based multiregime combustion models on the basis of single regime tabulated flamelet databases. In the present study, a new definition of the premixedness index ζPF is proposed for partially premixed combustion. It is based on a weighted form of the cross-scalar dissipation rate of the mixture fraction Yξ and progress variable Yc, i.e. quantities that have been previously identified as relevant parameters to describe partially premixed combustion regimes. The relevance of the corresponding index is assessed through a detailed computational procedure that includes three successive validation subsets: counterflow flames (including premixed, rich partially-premixed, and diffusion flames), (ii) stabilised triple flames for three distinct values of the inlet mixture fraction gradient, and finally (iii) unsteady flame kernel developments in non-homogeneous mixtures of fresh reactants, which are characterised by various initial levels of the segregation rate between the fuel and oxidiser. The proposed premixedness index ζPF and its counterpart ζDF=1−ζPF are used as the weighting coefficients between tabulated premixed flamelets (TPF) and tabulated diffusion flamelets (TDF) data, which have been parameterised as functions of Yξ and Yc. It is noteworthy that, in contrast to some previous proposals of the literature, the present flame index does not require the consideration of any other quantities in addition to those already used to parameterise the flamelets databases, i.e. Yξ and Yc. The validation procedure makes use of steady and unsteady processes with a priori and a posteriori analyses. In both cases, the comparisons between the results obtained with the proposed flame partitioning and detailed chemistry (DC) computations lead to a satisfactory level of agreement and, from a general viewpoint, the level of agreement is better than the one obtained with either premixed or diffusion flamelet-based models. ; Funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) – Project-ID 422037413 – TRR 287. Daniel Mira acknowledges the funding received through the Spanish Ministry of Economy and Competitiveness in the frame of the CHEST project (TRA2017-89139-C2-2-R) and the ESTiMatE project from the Clean Sky 2 Joint Undertaking under the European Union's Horizon 2020 research and innovation programme under grant agreement No 821418. Conflict of Interest: Daniel Mira acknowledges the Juan de la Cierva personal grant IJCI-2015-26686. ; Peer Reviewed ; Postprint (author's final draft)

This paper describes the development and successful pilot of rotational placements by the social work faculty of a large Canadian university. Modifications required for the pilot are discussed, particularly related to recruiting settings, enlisting field instructors and students, developing new field materials, training field instructors in the model and developing an evaluation tool used by field instructors and students. The strengths, limitations and lessons learned from the experience are discussed as well as the potential usefulness of rotational placements as an approach to addressing resource challenges in field education.

Contribución presentada al IV Congreso Internacional de Universidades Promotoras de Salud: el compromiso social de las universidades, organizado por la Universidad Pública de Navarra y el Instituto de Salud Pública del Gobierno de Navarra, celebrado entre los días 7 y 9 de octubre de 2009 en Pamplona/Iruña. ; Revisiting mothering as a personal, social, political and economical problem. Key object of study in feminist theories. Today becomes a topic of debate in social sciences. This research looks at the difficulties faced by female researchers when they try to progress in their academic trajectory.

Presented at the XXVII International Conference of Theoretical Physics, "Matter to the Deepest", Ustron, Poland, september 15-21, 2003. ; In supersymmetric (SUSY) models the misalignment between fermion and sfermion families introduces unsuppressed flavour-changing processes. Even if the mass parameters are chosen to give no flavour violation, family dependent radiative corrections make this adjustment not stable. In par- ticular, due to the observed large neutrino mixings and potentially large neutrino Yukawa couplings, sizable lepton flavour violation (LFV) is ex- pected. After introducing the basic concepts, the framework and the main assumptions, we report on a recent study of rare leptonic decays in a class of SUSY–GUT models with three quasi-degenerate neutrinos. We show that LFV effects are likely visible in forthcoming experiments. ; This work has been supported by the Spanish CICYT, the Junta de Andalucía and the European Union under contracts FPA2000-1558, FQM 101, and HPRN-CT-2000-00149, respectively.

We would like to thank Mar Bastero, Adrian Carmona, Mikael R. Chala, Miguel Escud-ero, Javier Olmedo, Jose Santiago and Samuel Witte for discussions. This work was par-tially supported by the Spanish Ministry of Science, Innovation and Universities (PID2019-107844GB-C21/AEI/10.13039/501100011033) and by the Junta de Andalucia (FQM 101, SOMM17/6104/UGR, P18-FR-1962, P18-FR-5057) . ; We propose a singlet majoron model that defines an inverse seesaw mechanism in the v sector. The majoron phi has a mass m(phi) approximate to 0.5 eV and a coupling to the tau lepton similar to the one to neutrinos. In the early universe it is initially in thermal equilibrium, then it decouples at T approximate to 500 GeV and contributes with just Delta N-eff = 0.026 during BBN. At T = 26 keV (final stages of BBN) a primordial magnetic field induces resonant gamma phi oscillations that transfer 6% of the photon energy into majorons, implying Delta N-eff = 0.55 and a 4.7% increase in the baryon to photon ratio. At T approximate to m(phi) the majoron enters in thermal contact with the heaviest neutrino and it finally decays into v (v) over bar pairs near recombination, setting Delta N-eff = 0.85. The boost in the expansion rate at later times may relax the Hubble tension (we obtain H-0 = (71.4 +/- 0.5) km/s/Mpc), while the processes v (v) over bar phi suppress the free streaming of these particles and make the model consistent with large scale structure observations. Its lifetime and the fact that it decays into neutrinos instead of photons lets this axion-like majoron avoid the strong bounds that affect other axion-like particles of similar mass and coupling to photons. ; Spanish Government PID2019-107844GB-C21/AEI/10.13039/501100011033 ; Junta de Andalucia FQM 101 SOMM17/6104/UGR P18-FR-1962 P18-FR-5057

Full list of authors: Goddi, Ciriaco; Martí-Vidal, Iván; Messias, Hugo; Bower, Geoffrey C.; Broderick, Avery E.; Dexter, Jason; Marrone, Daniel P.; Moscibrodzka, Monika; Nagai, Hiroshi; Algaba, Juan Carlos; Asada, Keiichi; Crew, Geoffrey B.; Gómez, José L.; Impellizzeri, C. M. Violette; Janssen, Michael; Kadler, Matthias; Krichbaum, Thomas P.; Lico, Rocco; Matthews, Lynn D.; Nathanail, Antonios Ricarte, Angelo; Ros, Eduardo; Younsi, Ziri; Akiyama, Kazunori; Alberdi, Antxon; Alef, Walter; Anantua, Richard; Azulay, Rebecca; Baczko, Anne-Kathrin; Ball, David; Baloković, Mislav; Barrett, John; Benson, Bradford A.; Bintley, Dan; Blackburn, Lindy; Blundell, Raymond; Boland, Wilfred; Bouman, Katherine L.; Boyce, Hope; Bremer, Michael; Brinkerink, Christiaan D.; Brissenden, Roger; Britzen, Silke; Broguiere, Dominique; Bronzwaer, Thomas; Byun, Do-Young; Carlstrom, John E.; Chael, Andrew; Chan, Chi-kwan; Chatterjee, Shami; Chatterjee, Koushik; Chen, Ming-Tang; Chen, Yongjun; Chesler, Paul M.; Cho, Ilje; Christian, Pierre; Conway, John E.; Cordes, James M.; Crawford, Thomas M.; Cruz-Osorio, Alejandro; Cui, Yuzhu; Davelaar, Jordy; De Laurentis, Mariafelicia; Deane, Roger; Dempsey, Jessica; Desvignes, Gregory; Doeleman, Sheperd S.; Eatough, Ralph P.; Falcke, Heino; Farah, Joseph; Fish, Vincent L.; Fomalont, Ed; Ford, H. Alyson; Fraga-Encinas, Raquel; Freeman, William T.; Friberg, Per; Fromm, Christian M.; Fuentes, Antonio; Galison, Peter; Gammie, Charles F.; García, Roberto; Gentaz, Olivier; Georgiev, Boris; Gold, Roman; Gómez-Ruiz, Arturo I.; Gu, Minfeng; Gurwell, Mark; Hada, Kazuhiro; Haggard, Daryl; Hecht, Michael H.; Hesper, Ronald; Ho, Luis C.; Ho, Paul; Honma, Mareki; Huang, Chih-Wei L.; Huang, Lei; Hughes, David H.; Inoue, Makoto; Issaoun, Sara; James, David J.; Jannuzi, Buell T.; Jeter, Britton; Jiang, Wu; Jimenez-Rosales, Alejandra; Johnson, Michael D.; Jorstad, Svetlana; Jung, Taehyun; Karami, Mansour; Karuppusamy, Ramesh; Kawashima, Tomohisa; Keating, Garrett K.; Kettenis, Mark; Kim, Dong-Jin; Kim, Jae-Young; Kim, Jongsoo; Kim, Junhan; Kino, Motoki; Koay, Jun Yi; Kofuji, Yutaro; Koch, Patrick M.; Koyama, Shoko; Kramer, Michael; Kramer, Carsten; Kuo, Cheng-Yu; Lauer, Tod R.; Lee, Sang-Sung; Levis, Aviad; Li, Yan-Rong; Li, Zhiyuan; Lindqvist, Michael; Lindahl, Greg; Liu, Jun; Liu, Kuo; Liuzzo, Elisabetta; Lo, Wen-Ping; Lobanov, Andrei P.; Loinard, Laurent; Lonsdale, Colin; Lu, Ru-Sen; MacDonald, Nicholas R.; Mao, Jirong; Marchili, Nicola; Markoff, Sera; Marscher, Alan P.; Matsushita, Satoki; Medeiros, Lia; Menten, Karl M.; Mizuno, Izumi; Mizuno, Yosuke; Moran, James M.; Moriyama, Kotaro; Müller, Cornelia; Musoke, Gibwa; Mejías, Alejandro Mus; Nagar, Neil M.; Nakamura, Masanori; Narayan, Ramesh; Narayanan, Gopal; Natarajan, Iniyan; Neilsen, Joey; Neri, Roberto; Ni, Chunchong; Noutsos, Aristeidis; Nowak, Michael A.; Okino, Hiroki; Olivares, Héctor; Ortiz-León, Gisela N.; Oyama, Tomoaki; Özel, Feryal; Palumbo, Daniel C. M.; Park, Jongho; Patel, Nimesh; Pen, Ue-Li; Pesce, Dominic W.; Piétu, Vincent; Plambeck, Richard; PopStefanija, Aleksandar; Porth, Oliver; Pötzl, Felix M.; Prather, Ben; Preciado-López, Jorge A.; Psaltis, Dimitrios; Pu, Hung-Yi; Ramakrishnan, Venkatessh; Rao, Ramprasad; Rawlings, Mark G.; Raymond, Alexander W.; Rezzolla, Luciano; Ripperda, Bart; Roelofs, Freek; Rogers, Alan; Rose, Mel; Roshanineshat, Arash; Rottmann, Helge; Roy, Alan L.; Ruszczyk, Chet; Rygl, Kazi L. J.; Sánchez, Salvador; Sánchez-Arguelles, David; Sasada, Mahito; Savolainen, Tuomas; Schloerb, F. Peter; Schuster, Karl-Friedrich; Shao, Lijing; Shen, Zhiqiang; Small, Des; Sohn, Bong Won; SooHoo, Jason; Sun, He; Tazaki, Fumie; Tetarenko, Alexandra J.; Tiede, Paul; Tilanus, Remo P. J.; Titus, Michael; Toma, Kenji; Torne, Pablo; Trent, Tyler; Traianou, Efthalia; Trippe, Sascha; van Bemmel, Ilse; van Langevelde, Huib Jan; van Rossum, Daniel R.; Wagner, Jan; Ward-Thompson, Derek; Wardle, John; Weintroub, Jonathan; Wex, Norbert; Wharton, Robert; Wielgus, Maciek; Wong, George N.; Wu, Qingwen; Yoon, Doosoo; Young, André; Young, Ken; Yuan, Feng; Yuan, Ye-Fei; Zensus, J. Anton; Zhao, Guang-Yao; Zhao, Shan-Shan; Bruni, Gabriele; Gopakumar, A.; Hernández-Gómez, Antonio; Herrero-Illana, Ruben; Ingram, Adam; Komossa, S.; Kovalev, Y. Y.; Muders, Dirk; Perucho, Manel; Rösch, Florian; Valtonen, Mauri.--Original content from this work may be used under the terms of the Creative Commons Attribution 4.0 licence. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI. ; We present the results from a full polarization study carried out with the Atacama Large Millimeter/submillimeter Array (ALMA) during the first Very Long Baseline Interferometry (VLBI) campaign, which was conducted in 2017 April in the λ3 mm and λ1.3 mm bands, in concert with the Global mm-VLBI Array (GMVA) and the Event Horizon Telescope (EHT), respectively. We determine the polarization and Faraday properties of all VLBI targets, including Sgr A*, M87, and a dozen radio-loud active galactic nuclei (AGNs), in the two bands at several epochs in a time window of 10 days. We detect high linear polarization fractions (2%–15%) and large rotation measures (RM > 103.3–105.5 rad m−2), confirming the trends of previous AGN studies at millimeter wavelengths. We find that blazars are more strongly polarized than other AGNs in the sample, while exhibiting (on average) order-of-magnitude lower RM values, consistent with the AGN viewing angle unification scheme. For Sgr A* we report a mean RM of (−4.2 ± 0.3) × 105 rad m−2 at 1.3 mm, consistent with measurements over the past decade and, for the first time, an RM of (–2.1 ± 0.1) × 105 rad m−2 at 3 mm, suggesting that about half of the Faraday rotation at 1.3 mm may occur between the 3 mm photosphere and the 1.3 mm source. We also report the first unambiguous measurement of RM toward the M87 nucleus at millimeter wavelengths, which undergoes significant changes in magnitude and sign reversals on a one year timescale, spanning the range from −1.2 to 0.3 × 105 rad m−2 at 3 mm and −4.1 to 1.5 × 105 rad m−2 at 1.3 mm. Given this time variability, we argue that, unlike the case of Sgr A*, the RM in M87 does not provide an accurate estimate of the mass accretion rate onto the black hole. We put forward a two-component model, comprised of a variable compact region and a static extended region, that can simultaneously explain the polarimetric properties observed by both the EHT (on horizon scales) and ALMA (which observes the combined emission from both components). These measurements provide critical constraints for the calibration, analysis, and interpretation of simultaneously obtained VLBI data with the EHT and GMVA. © 2021. The American Astronomical Society. ; ALMA is a partnership of the European Southern Observatory (ESO; Europe, representing its member states), NSF, andNational Institutes of Natural Sciences of Japan, together with National Research Council (Canada), Ministry of Science and Technology (MOST; Taiwan), Academia Sinica Institute of Astronomy and Astrophysics (ASIAA; Taiwan), and Korea Astronomy and Space Science Institute (KASI; Republic of Korea), in cooperation with the Republic of Chile. The Joint ALMA Observatory is operated by ESO, Associated Universities, Inc. (AUI)/NRAO, and the National Astronomical Observatory of Japan (NAOJ). The NRAO is a facility of the NSF operated under cooperative agreement by AUI. This Letter makes use of the following ALMA data: ADS/JAO.ALMA#2016.1.00413.V ADS/JAO.ALMA#2016. 1.01116.V ADS/JAO.ALMA#2016.1.01216.V ADS/JAO. ALMA#2016.1.01114.V ADS/JAO.ALMA#2016.1.01154.V ADS/JAO.ALMA#2016.1.01176.V ADS/JAO.ALMA#2016. 1.01198.V ADS/JAO.ALMA#2016.1.01290.V ADS/JAO. ALMA#2016.1.01404.V ADS/JAO.ALMA#2017.1.00841.V ADS/JAO.ALMA#2013.1.01022.S ADS/JAO.ALMA#2015. 1.01170.S ADS/JAO.ALMA#2016.1.00415.S ADS/JAO. ALMA#2017.1.00608.S The authors of the present Letter thank the following organizations and programs: the Academy of Finland (projects 274477, 284495, 312496, 315721); the Advanced European Network of E-infrastructures for Astronomy with the SKA (AENEAS) project, supported by the European Commission Framework Programme Horizon 2020 Research and Innovation action under grant agreement 731016; the Alexander von Humboldt Stiftung; an Alfred P. Sloan Research Fellowship; Allegro, the European ALMA Regional Centre node in the Netherlands, the NL astronomy research network NOVA and the astronomy institutes of the University of Amsterdam, Leiden University and Radboud University; the black hole Initiative at Harvard University, through a grant (60477) from the John Templeton Foundation; the China Scholarship Council; Agencia Nacional de Investigacion y Desarrollo (ANID), Chile via NCN19_058 (TITANs) and Fondecyt 3190878; Consejo Nacional de Ciencia y Tecnologia (CONACYT, Mexico, projects U0004-246083, U0004-259839, F0003-272050, M0037-279006, F0003-281692, 104497, 275201, 263356); the Delaney Family via the Delaney Family John A. Wheeler Chair at Perimeter Institute; Direccion General de Asuntos del Personal AcademicoUniversidad Nacional Autonoma de Mexico (DGAPA-UNAM, projects IN112417 and IN112820); the European Research Council Synergy Grant "BlackHoleCam: Imaging the Event Horizon of Black Holes" (grant 610058); the Generalitat Valenciana postdoctoral grant APOSTD/2018/177 and GenT Program (project CIDEGENT/2018/021); MICINN Research Project PID2019-108995GB-C22; the Gordon and Betty Moore Foundation (grants GBMF-3561, GBMF-5278); the Istituto Nazionale di Fisica Nucleare (INFN) sezione di Napoli, iniziative specifiche TEONGRAV; the International Max Planck Research School for Astronomy and Astrophysics at the Universities of Bonn and Cologne; the Jansky Fellowship program of the National Radio Astronomy Observatory (NRAO); Joint Princeton/Flatiron and Joint Columbia/Flatiron Postdoctoral Fellowships, research at the Flatiron Institute is supported by the Simons Foundation; the Japanese Government (Monbukagakusho: MEXT) Scholarship; the Japan Society for the Promotion of Science (JSPS) Grant-in-Aid for JSPS Research Fellowship (JP17J08829); the Key Research Program of Frontier Sciences, Chinese Academy of Sciences (CAS, grants QYZDJ-SSWSLH057, QYZDJSSW-SYS008, ZDBS-LY-SLH011); the Leverhulme Trust Early Career Research Fellowship; the MaxPlanck-Gesellschaft (MPG); the Max Planck Partner Group of the MPG and the CAS; the MEXT/JSPS KAKENHI (grants 18KK0090, JP18K13594, JP18K03656, JP18H03721, 18K03709, 18H01245, 25120007); the Malaysian Fundamental Research Grant Scheme (FRGS) FRGS/1/2019/STG02/UM/02/6; the MIT International Science and Technology Initiatives (MISTI) Funds; the Ministry of Science and Technology (MOST) of Taiwan (105-2112-M-001-025-MY3, 106-2112-M-001-011, 106-2119-M-001-027, 107-2119-M-001-017, 107-2119-M-001020, and 107-2119-M-110-005, MOST 108-2112-M-001-048 and MOST 109-2124-M-001-005); the National Aeronautics and Space Administration (NASA, Fermi Guest Investigator grant 80NSSC20K1567, NASA Astrophysics Theory Program grant 80NSSC20K0527, and Hubble Fellowship grant HST-HF251431.001-A awarded by the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc. , for NASA, under contract NAS5-26555,); the National Institute of Natural Sciences (NINS) of Japan; the National Key Research and Development Program of China (grant 2016YFA0400704, 2016YFA0400702); the National Science Foundation (NSF, grants AST-0096454, AST-0352953, AST-0521233, AST-0705062, AST-0905844, AST-0922984, AST-1126433, AST-1140030, DGE-1144085, AST-1207704, AST-1207730, AST-1207752, MRI-1228509, OPP-1248097, AST-1310896, AST-1337663, AST-1440254, AST-1555365, AST-1615796, AST-1715061, AST-1716327, AST-1716536, OISE-1743747, AST-1816420, AST-1903847, AST-1935980, AST-2034306); the Natural Science Foundation of China (grants 11573051, 11633006, 11650110427, 10625314, 11721303, 11725312, 11933007, 11991052, 11991053); a fellowship of China Postdoctoral Science Foundation (2020M671266); the Natural Sciences and Engineering Research Council of Canada (NSERC, including a Discovery Grant and the NSERC Alexander Graham Bell Canada Graduate Scholarships-Doctoral Program); the National Youth Thousand Talents Program of China; the National Research Foundation of Korea (the Global PhD Fellowship Grant: grants NRF-2015H1A2A1033752, 2015R1D1A1A01056807, the Korea Research Fellowship Program: NRF-2015H1D3A1066561, Basic Research Support Grant 2019R1F1A1059721); the Netherlands Organization for Scientific Research (NWO) VICI award (grant 639.043.513) and Spinoza Prize SPI 78-409; the New Scientific Frontiers with Precision Radio Interferometry Fellowship awarded by the South African Radio Astronomy Observatory (SARAO), which is a facility of the National Research Foundation (NRF), an agency of the Department of Science and Technology (DST) of South Africa; the Onsala Space Observatory (OSO) national infrastructure, for the provisioning of its facilities/observational support (OSO receives funding through the Swedish Research Council under grant 2017-00648) the Perimeter Institute for Theoretical Physics (research at Perimeter Institute is supported by the Government of Canada through the Department of Innovation, Science and Economic Development and by the Province of Ontario through the Ministry of Research, Innovation and Science); the Spanish Ministerio de Economia y Competitividad (grants PGC2018098915-B-C21, AYA2016-80889-P, PID2019-108995GB-C21); the State Agency for Research of the Spanish MCIU through the "Center of Excellence Severo Ochoa" award for the Instituto de Astrofisica de Andalucia (SEV-2017-0709); the Toray Science Foundation; the Consejeria de Economia, Conocimiento, Empresas y Universidad of the Junta de Andalucia (grant P18-FR-1769), the Consejo Superior de Investigaciones Cientificas (grant 2019AEP112); the US Department of Energy (USDOE) through the Los Alamos National Laboratory (operated by Triad National Security, LLC, for the National Nuclear Security Administration of the USDOE (Contract 89233218CNA000001); the Italian Ministero dell'Istruzione Universita e Ricerca through the grant Progetti Premiali 2012-iALMA (CUP C52I13000140001); the European Union's Horizon 2020 research and innovation program under grant agreement No 730562 RadioNet; ALMA North America Development Fund; the Academia Sinica; Chandra TM6-17006X; the GenT Program (Generalitat Valenciana) Project CIDEGENT/2018/021; NASA NuSTAR award 80NSSC20K0645; Chandra award DD7-18089X. This work used the Extreme Science and Engineering Discovery Environment (XSEDE), supported by NSF grant ACI-1548562, and CyVerse, supported by NSF grants DBI-0735191, DBI-1265383, and DBI-1743442. XSEDE Stampede2 resource at TACC was allocated through TG-AST170024 and TG-AST080026N. XSEDE JetStream resource at PTI and TACC was allocated through AST170028. The simulations were performed in part on the SuperMUC cluster at the LRZ in Garching, on the LOEWE cluster in CSC in Frankfurt, and on the HazelHen cluster at the HLRS in Stuttgart. This research was enabled in part by support provided by Compute Ontario (http://computeontario.ca), Calcul Quebec (http://www.calculquebec.ca) and Compute Canada (http://www.computecanada.ca).We thank the staff at the participating observatories in the GMVA and EHT, correlation centers, and institutions for their enthusiastic support. The GMVA is coordinated by the VLBI group at the Max-Planck-Institut fur Radioastronomie (MPIfR) and consists of telescopes operated by MPIfR, IRAM, Onsala, Metsahovi, Yebes, the Korean VLBI Network, the Green Bank Observatory and the VLBA. APEX is a collaboration between the MPIfR (Germany), ESO, and the Onsala Space Observatory (Sweden). The SMA is a joint project between the SAO and ASIAA and is funded by the Smithsonian Institution and the Academia Sinica. The JCMT is operated by the East Asian Observatory on behalf of the NAOJ, ASIAA, and KASI, as well as the Ministry of Finance of China, Chinese Academy of Sciences, and the National Key R&D Program (No. 2017YFA0402700) of China. Additional funding support for the JCMT is provided by the Science and Technologies Facility Council (UK) and participating universities in the UK and Canada. The LMT is a project operated by the Instituto Nacional de Astrofisica, Optica, y Electronica (Mexico) and the University of Massachusetts at Amherst (USA). The IRAM 30m telescope on Pico Veleta, Spain is operated by IRAM and supported by CNRS (Centre National de la Recherche Scientifique, France), MPG (Max-Planck-Gesellschaft, Germany) and IGN (Instituto Geografico Nacional, Spain). The SMT is operated by the Arizona Radio Observatory, a part of the Steward Observatory of the University of Arizona, with financial support of operations from the State of Arizona and financial support for instrumentation development from the NSF. The SPT is supported by the National Science Foundation through grant PLR-1248097. Partial support is also provided by the NSF Physics Frontier Center grant PHY-1125897 to the Kavli Institute of Cosmological Physics at the University of Chicago, the Kavli Foundation and the Gordon and Betty Moore Foundation grant GBMF 947. The SPT hydrogen maser was provided on loan from the GLT, courtesy of ASIAA. The EHTC has received generous donations of FPGA chips from Xilinx Inc., under the Xilinx University Program. The EHTC has benefited from technology shared under open-source license by the Collaboration for Astronomy Signal Processing and Electronics Research (CASPER). The EHT project is grateful to T4Science and Microsemi for their assistance with Hydrogen Masers. This research has made use of NASA's Astrophysics Data System. We gratefully acknowledge the support provided by the extended staff of the ALMA, both from the inception of the ALMA Phasing Project through the observational campaigns of 2017 and 2018. We would like to thank A. Deller and W. Brisken for EHT-specific support with the use of DiFX. We thank Sergio Martin for the help interpreting the Sgr A* spectrum in SPW= 2. We acknowledge the significance that Maunakea, where the SMA and JCMT EHT stations are located, has for the indigenous Hawaiian people. M.P. acknowledges support by the Spanish Ministry of Science through Grants PID2019-105510GB-C31, and PID2019-107427GB-C33, and from the Generalitat Valenciana through grant PROMETEU/2019/071. ; Peer reviewed

Enteric adenoviruses, one of the main causes of viral gastroenteritis in the world, must withstand the harsh conditions found in the gut. This requirement suggests that capsid stability must be different from that of other adenoviruses. We report the 4-Å-resolution structure of a human enteric adenovirus, HAdV-F41, and compare it with that of other adenoviruses with respiratory (HAdV-C5) and ocular (HAdV-D26) tropisms. While the overall structures of hexon, penton base, and internal minor coat proteins IIIa and VIII are conserved, we observe partially ordered elements reinforcing the vertex region, which suggests their role in enhancing the physicochemical capsid stability of HAdV-F41. Unexpectedly, we find an organization of the external minor coat protein IX different from all previously characterized human and nonhuman mastadenoviruses. Knowledge of the structure of enteric adenoviruses provides a starting point for the design of vectors suitable for oral delivery or intestinal targeting ; This work was supported by grants PID2019-104098GB-I00/AEI/10.13039/501100011033 and BFU2016-74868-P, cofunded by the Spanish State Research Agency and the European Regional Development Fund; BFU2013-41249-P and BIO2015-68990-REDT (the Spanish Adenovirus Network, AdenoNet) from the Spanish Ministry of Economy, Industry, and Competitiveness; and the Agencia Estatal CSIC (2019AEP045) to C.S.M. The CNB-CSIC is further supported by a Severo Ochoa Excellence grant (SEV 2017-0712). Work in M.B's. lab was supported by grant 194562-08 from the Natural Sciences and Engineering Research Council of is a recipient of a Juan de la Cierva postdoctoral contract funded by the Spanish State Research Agency. M.P.-I. holds a predoctoral contract from La Caixa Foundation (ID 100010434), under agreement LCF/BQ/SO16/52270032. Access to CEITEC was supported by iNEXT, project number 653706, funded by the Horizon 2020 Programme of the European Union. The CEITEC Cryo-electron Microscopy and Tomography core facility is supported by MEYS CR (LM2018127)