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This study examines the impact of the Internet on the well-being of older Chinese. Thirty-three older Chinese, who were current or former students of a senior-oriented computer training organization based in Shanghai, China, were interviewed about their use and perceptions of the Internet. Data analysis was guided by grounded theory. The findings indicate that Internet learning and use in this peer group makes these older Chinese's lives after retirement more meaningful, and improves their self-evaluations as well as other people's views of them. These findings suggest that Internet learning and use is positively associated with the well-being of these older Chinese. This study also finds culturally specific factors—including mandatory retirement and recent economic reforms in China—that mediate older Chinese people's use and perceptions of the Internet. Finally, societal implications, limitations, and future research directions are discussed.

Fast urbanization produces a large and growing population in coastal areas. However, the increasing rise in sea levels, one of the most impacts of global warming, makes coastal communities much more vulnerable to flooding than before. While most existing work focuses on understanding the large-scale impacts of sea-level rise, this paper investigates parcel-level property impacts, using a specific coastal city, Tampa, Florida, USA, as an empirical study. This research adopts a spatial-temporal analysis method to identify locations of flooded properties and their costs over a future period. A corrected sea-level rise model based on satellite altimeter data is first used to predict future global mean sea levels. Based on high-resolution LiDAR digital elevation data and property maps, properties to be flooded are identified to evaluate property damage cost. This empirical analysis provides deep understanding of potential flooding risks for individual properties with detailed spatial information, including residential, commercial, industrial, agriculture, and governmental buildings, at a fine spatial scale under three different levels of global warming. The flooded property maps not only help residents to choose location of their properties, but also enable local governments to prevent potential sea-level rising risks for better urban planning. Both spatial and temporal analyses can be easily applied by researchers or governments to other coastal cities for sea-level rise- and climate change-related urban planning and management.

Fruit and vegetable (FV) consumption can improve older adults' health outcomes, but conventional interventions can be resource demanding and make it difficult to provide just-in-time intervention content. iPad-based interventions may help overcome these limitations, but little is known about how older adults might perceive and use iPads for FV consumption. To address this gap in the literature, we conducted a qualitative study to explore older adults' perceptions and use of iPads for improving FV consumption between February and August of 2012. Five focus group sessions each lasting 120 min were conducted with 22 older adult participants. During each session, participants received guided exposure and instruction on iPad use and then explored three iPad applications targeting FV consumption (MyFood, FiveADay Lite, and Whole Foods Market Recipes). Detailed notes from focus group interviews were analyzed with a grounded theory approach that applied a constant comparative method to enable themes to emerge from the data. Three themes were identified from the data regarding participants' baseline perceptions of iPads. These included (a) limited knowledge on iPad's functions, (b) iPads were intended for younger users, and (c) iPads were too expensive. Themes identified regarding participants' perceptions of iPads after guided exposure included (a) the touchscreen was easier to use than a computer mouse, (b) tapping the interface required practice, (c) portability was an asset in conjunction with functionality, (d) portability and functionality supported personal interests, (e) the difficulty of learning an iPad's functions varied, and (f) practice and instruction helped overcome fear of the iPad. Finally, participants recommended iPad app features that could help them overcome barriers to their FV intake. These included (a) locating inexpensive FV from nearby sources, (b) providing tailored food and recipe suggestions, and (c) tracking and communicating FV intake with a doctor. These findings have important implications for future research on mobile app-based eHealth interventions to improve older adults' FV intake.

BACKGROUND: A variety of policies have been implemented around the world in response to the COVID-19 pandemic. This study originally aimed to identify and compare policy responses of different countries and their effects on the pandemic. It quickly evolved into an identification of the heterogeneity among existing policies and the challenges in making meaningful comparisons of the impact of these policies. METHODS: The process of collecting and comparing data from different sources was analysed through inductive thematic analysis to understand the obstacles that impede research designed to compare COVID-19 data and related policies. RESULTS: We identified the following obstacles: (1) no single reputable source of information and too much noise; (2) a lack of standards for how to measure and report data across countries; (3) variations in the content, implementation and enforcement of policies; and (4) politics, instead of science, leading the efforts in pandemic management. CONCLUSION: Heterogeneity in existing policies makes it challenging to compare the effects of various policies worldwide on the COVID-19 pandemic. Our findings call for an automatically updated informatics infrastructure across the globe for collecting and maintaining standardized data from multiple sources. There is a strong need for steadfast utilization of scientific and technical experts to inform and influence health policy. Increased investment in public health and emergency planning is essential to overcome the current pandemic, as well as future public health emergencies. Focused leadership and collaboration from world leaders in a unified mission to decrease the mortality and morbidity of the COVID-19 pandemic is imperative.

Abstract
Older adults, 65 years and older, are a heterogeneous group in terms of their information and communication technology (ICT) use. Few studies, however, have examined how ICT use patterns may vary between employed older adults versus those who are no longer in the workforce. We expand research on this topic by examining whether variations in ICT use, as well as attitudes toward ICTs and online self-efficacy, exist between these 2 groups. Key outcomes include online self-efficacy, attitudes towards new technology, length of time online, average daily hours online, and number of ICTs used. Data were collected in 2017 through an online survey from a national sample of U.S. older adults (N = 1,142) matched with the demographic characteristics of the 2010 U.S. Census for individuals aged 65 and older based on age, race, sex, and education. Data were analyzed using OLS regression, binary logistic regression, and mediation analysis. Employed older adults, compared to retired older adults, had higher online self-efficacy, more positive attitudes towards new technology, spent more time online (years), and were more likely to use 2 or more ICTs. Being retired was associated with fewer years online, which was mediated by more negative attitudes toward technology and less online self-efficacy. Longitudinal research is needed which examines the types of technologies used in the workforce by older adults, the exposure to others' uses of technologies, and how use changes over time—all of which may potentially affect older adults' technology skills and attitudes.

Abstract
In recent years, the COVID-19 pandemic and other global crises have significantly affected the lives of older adults, impacting their healthcare, social connections, and daily routines. While the increasing digitization and automation of services offer benefits such as remote healthcare access and reduced isolation, these technologies also pose challenges in terms of unfamiliarity, learning curves, and privacy and security concerns. Addressing these issues requires a collaborative approach across various fields, including health informatics, gerontology, social psychology, human–computer interaction, and cybersecurity and privacy. Understanding the cognitive, emotional, and sociocultural factors influencing older adults' use of technologies is crucial for creating inclusive and accessible digital tools. This multidisciplinary effort, as highlighted in the special issue of Work, Aging and Retirement, aims to enhance our understanding of aging and technology in today's world, empowering older adults to remain connected and maintain their well-being.

AbstractTechnological advancements continue to result in fundamental changes to the work itself and the workplace. Although these changes can create challenges for older workers, older workers can draw from individual and contextual resources to maintain and enhance their wellbeing, motivation, and capacities, and thus achieving successful aging at work. These articles in this special issue characterize the different psychological mechanisms underlying workers' responses to technological changes in the workplace, such as automation, digitization, and use of information and communications technologies. Integrating the findings from these articles, along with the existing theoretical models of successful aging at work, we propose a socio-ecological approach to guide future research on older workers' adaptation to technological changes.

AbstractHomeless people have become more visible in China in recent years. However, research on Chinese homelessness in general and homeless migrants in particular is still very limited. Based on the China Migrants Dynamic Survey, this pioneering exploration of the geography of homeless migrants in China arrives at three conclusions. First, although homeless migrants are often scorned as an underclass of derelict drifters, the majority are educated, married, and employed, sometimes temporarily. Second, although most homeless migrants congregate in the most developed coastal regions, the number of homeless migrants as a proportion of total migrants is relatively high in some remote provinces, with significant numbers residing in rural areas. Third, in addition to the three established drivers: the housing market, economic opportunity, and social support, prejudice towards the homeless is shown to be an important factor in the concentration of homeless migrants and their exclusion from urban society. This paper contributes to an understanding of homeless migrants in China and the factors accounting for their spatial distribution.

A closed-loop supply chain operation is an effective way to improve the dual benefits of economy and environment. Inspired by the practice of closed-loop supply chain coordination, this paper attempts to investigate the supply chain operation strategies of different recycling modes and patent licensing strategies and consider the impact of government subsidies. We construct a multi-player game model of an original manufacturer, a remanufacturer, and a retailer under a waste product recycling mode, patent licensing strategy, and government subsidy system. We provide the operation strategies under different strategy combinations in the closed-loop supply chain, and then analyze their differences and the interests of various subjects. We further analyze the impact of government subsidies on the operation strategies of the supply chain. The results illustrate that when the original manufacturer adopts the fixed fee patent licensing strategy, the recycling price of waste products is higher. When the original manufacturer adopts the unit fee patent licensing strategy and the retailer and the remanufacturer participate in the recycling of waste products simultaneously, the original manufacturer will increase the unit patent licensing fee. When the remanufacturer recycles waste products alone, consumers can obtain greater unit income in the waste product recycling market. Different government subsidies have different effects on the wholesale price and the retail price of new products and remanufactured products.

Bo Xie, Liyue Sun, Yanjun Cheng, Juan Zhou, Jihua Zheng, Weimin Zhang Department of Oncology, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou, Guangdong, People's Republic of China Introduction: There is still lack of specific biomarkers in predicting the radiosensitivity of non-small cell lung cancer (NSCLC) patients in clinic. Previous studies have shown that the EGFR gene status may correlate with radiosensitivity of NSCLC. However, the underlying mechanisms remain unknown. The aim of this study was to further investigate the correlation between EGFR mutation status and the NSCLC cell radiosensitivity and to explore the possible cellular mechanism. Methods: Eight NSCLC cell lines with different EGFR gene status were irradiated by linear accelerator, and the radiosensitivity between the cell lines was compared by cell colony formation assay and cell proliferation assay. Cell cycle and apoptosis were analysed by flow cytometry. Radiosensitivity-related protein expression was detected by Western blotting.Results: In the present study, we found that NSCLC cell lines with the epidermal growth factor receptor (EGFR) gene mutations were more sensitive to X-ray irradiation than those with wild-type EGFR (P<0.05). No difference in radiosensitivity was observed between NSCLC cells with EGFR exon19 deletion (Del 19) mutation and exon 21 point mutation at position 858 (L858R) with or without T790M mutation (P<0.05), as well as between NSCLC cells with EGFR mutation and those with acquired EGFR-tyrosine kinase inhibitors (TKIs) resistance. Mechanistically, EGFR mutations promoted NSCLC cell apoptosis in response to X-ray irradiation through the upregulation of proapoptotic protein Bax and downregulation of anti-apoptotic proteins such as Bcl-2 and DNA-dependent protein kinase catalytic subunit. In addition, phosphorylated histone (γ-H2AX) foci assay showed that EGFR mutations sustained irradiation-induced DNA damage. Conclusion: Taken together, our study demonstrates that EGFR mutations are closely associated with the increased sensitivity of NSCLC cell lines to X-ray irradiation and that EGFR mutation status is a potentially useful indicator to evaluate the effectiveness of radiotherapy in the treatment of NSCLC. Keywords: non-small-cell lung cancer, epidermal growth factor receptor, mutation, radiosensitivityErratum for this paper has been published

Xie B, Sun LY, Cheng YJ, et al. Cancer Manag Res. 2018;10;3551–3560.On page 3551, the affiliation section should be changed from: Bo XieLiyue SunYanjun ChengJuan ZhouJihua ZhengWeimin ZhangDepartment of Oncology, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou, Guangdong, People's Republic of ChinaTo: Bo Xie*Liyue Sun*Yanjun ChengJuan ZhouJihua ZhengWeimin ZhangDepartment of Oncology, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou, Guangdong, People's Republic of China*These authors contributed equally to this work.Read the original article