Suchergebnisse

Ferrocene and its derivatives have been extensively used as an internal reference in electrochemical processes. Yet, they possess limitations such as solvent restrictions that require chemical modifications. In this regard, we have studied the use of metallacarboranes [3,3'-M(1,2-C2B9H11)2]- (M = Co, Fe) as general internal reference systems and have proven their suitability by thoroughly investigating their electrochemical properties in both aqueous and organic electrolytes without any derivatization. ; This work was funded by the Spanish Ministry of Science, through the ''Severo Ochoa'' Programme for Centres of Excellence in R&D (CEX2019-000917-S) as well as the Ministerio de Economia y Competitividad (PID2019-106832RB-I00), (PID2020- 116728RB-I00, CTQ2015-71955-RED ELECTROBIONET) and Generalitat de Catalunya (2017SGR1720) are appreciated. J. A. M. Xavier acknowledges DOC-FAM programme under the Marie Sklodowska-Curie grant agreement no. 754397 and is enrolled in the PhD programme in UAB. Support from the Community of Madrid (TRANSNANOAVANSENS S2018/NMT-4349), is acknowledged. ; With funding from the Spanish government through the 'Severo Ochoa Centre of Excellence' accreditation (CEX2019-000917-S). ; Peer reviewed

Cobaltabis(dicarbollide) anion ([o-COSAN]- ) is a well-known metallacarborane with multiple applications in a variety of fields. In aqueous solution, the cisoid rotamer is the most stable disposition in the ground state. The present work provides theoretical evidence on the possibility to photoinduce the rotation from the cisoid to the transoid rotamer, a conversion that can be reverted when the ground state is repopulated. The non-radiative decay mechanisms proposed in this work are coherent with the lack of fluorescence observed in 3D fluorescence mapping experiments performed on [o-COSAN]- and its derivatives. This phenomenon induced by light has the potential to destruct the vesicles and micelles cisoid [o-COSAN]- typically forms in aqueous solution, which could lead to promising applications, particularly in the field of nanomedicine. ; This work was supported by the Generalitat Valenciana (GV, project GV/2020/226), Generalitat de Catalunya (2017 SGR 1720), and the Spanish Ministerio de Ciencia e Innovación (MICINN, projects CTQ2017-87054-C2-2–304-P and PID2019-106832RB-I00). A.M.A.A. is grateful to the Erasmus+ Programme of the European Comission for his Erasmus Mundus TCCM scholarship. A.F.-M. is grateful to the GV and the European Social Fund for the postdoctoral contract APOSTD/2019/149 and to the MICINN for the Juan de la Cierva contract IJC2019-039297-I. D.R.-S. is grateful to the MICINN for the "Ramón y Cajal" grant (RYC-2015–19234). "Severo Ochoa" Program for Centers of Excellence in R&D 234 (SEV-2015-0496) is appreciated. J. A. M. Xavier acknowledges DOC-FAM programme under the Marie Sklodowska-Curie grant agreement No. 754397 and is enrolled in the PhD program of the UAB. Computations have been conducted at the local QCEXVAL and the LluisVives and Tirant III clusters of the Servei d'Informàtica (University of Valencia). We thank Dr. Jordi Faraudo (ICMAB-CSIC) for the scientific discussions. ; With funding from the Spanish government through the 'Severo Ochoa Centre of Excellence' accreditation (CEX2019-000917-S). ; Peer reviewed

The aim of our study was to assess if the sodium salt of cobaltabis(dicarbollide) and its di-iodinated derivative (Na[o-COSAN] and Na[8,8'-I2-o-COSAN]) could be promising agents for dual anti-cancer treatment (chemotherapy + BNCT) for GBM. ; This work was supported by the Spanish Ministerio de Economía y Competitividad (PID2019-106832RB-I00, RTI2018-096273-B-I00), the Generalitat de Catalunya (2017SGR1720, 2017SGR765) and the 'Severo Ochoa' Program for Centers of Excellence in R&D (SEV-2015-0496), S. Geninatti Crich received funding from AIRC (Associazione Italiana per la Ricerca sul Cancro) under IG 2019—ID. 23267 project and by Fundação para a Ciência e Tecnologia (FCT) Portugal for projects UID/MULTI/04349/2019 and PTDC/BTM-TEC/29256/2017 and for the PhD scholarship DFA/BD/ 07119/2020 to C.I.G. Pinto. A.L. and A.M.-J. participate in the networks of EPNOE, Red Nanocare RED2018-102469-T, and CSIC Interdisciplinary Platform for Sustainable Plastics towards a Circular Economy, SUSPLAST). Jewel A.M. Xavier acknowledges the DOC-FAM program under the Marie Sklodowska-Curie grant agreement nº 754397. Miquel Nuez-Martinez, Jewel A.M. Xavier, and Amanda Muñoz-Juan (Ph.D. scholarship FPU18/05190) are enrolled in the Ph.D. program of the UAB. ; With funding from the Spanish government through the 'Severo Ochoa Centre of Excellence' accreditation (CEX2019-000917-S). ; Peer reviewed