Suchergebnisse

Most arable land in rural areas of China is highly fragmented, and promoting large-scale operation by means of farmland transfer is of great significance to both increase farm income and improve the ecological stability of farmland. At present, crayfish are widely popular with the consumer market, and the rice–crayfish cultivation pattern has considerable industrial advantages for water-rich plain areas. However, farmers do not have a sufficient understanding of the new model, and its application is not common enough, failing to realize the advantages of the region's special industries. The purpose of this paper is to analyze the current situation of farmland transfer in rice–crayfish cultivating regions of Hunan and Hubei, China, and employ the logistic regression model to explore the impacts of operation scale and transfer experience on farmers' willingness toward farmland transfer-in, in order to promote the sustainable development of rice–crayfish cultivating. The results showed that: Firstly, both operation scale and transfer experience have a significant positive relevance with farmers' willingness toward farmland transfer-in. Secondly, there are obvious differences in the impact path among large-scale, medium-scale, and small-scale rice or rice–crayfish farmers. Thirdly, the transfer-out experience is inhibitory or not significantly associated with the willingness toward farmland transfer-in. Fourthly, the transfer experience intensifies the positive influence of the expansion of operation scale on the farmers' willingness toward farmland transfer-in. This study can provide some reference and basis for the local government to make differentiated measures according to the farmland transfer preferences of farmers with different scales and operation types, so as to promote farmers' willingness to operate at a large scale and realize the sustainable development of the regional rice–crayfish cultivating model.

Jie Zheng,1,2,* Fuao Cao,3,* Xiaopei Huang,4,* Kuvaneshan Ramen,2 Xiaowen Xu,3 Yan Zhu,5 Wenjun Chang,4 Yunfeng Shan,2 Aizhen Guo1 1Department of General Medicine, Yangpu Hosptial, Tongji University School of Medicine, Shanghai 200090, People's Republic of China; 2Department of General Surgery, First Affiliated Hospital, Wenzhou Medical University, Zhejiang 325015, People's Republic of China; 3Department of Colorectal Surgery, Changhai Hospital, Second Military Medical University, Shanghai 200433, People's Republic of China; 4Department of Environmental Hygiene, Second Military Medical University, Shanghai 200433, People's Republic of China; 5Department of Pathology, Changhai Hospital, Second Military Medical University, Shanghai 200433, People's Republic of China *These authors contributed equally to this work Purpose: Eyes absent homologue 2 (EYA2), which functions as a transcription activator and phosphatase, plays an important role in several types of cancer. However, the impact of EYA2 in colorectal cancer (CRC) remains elusive. Patients and methods: We evaluated the significance of EYA2 expression in the development and progression of CRC in a large cohort, including 922 CRC cases. EYA2 protein expression was determined via immunohistochemistry in colorectal tissues. The correlation between EYA2 expression and CRC occurrence was investigated in tumor tissue and the adjacent normal tissues. Factors contributing to CRC prognosis were evaluated using Kaplan–Meier and Cox model analyses. Results: EYA2 expression was progressively lower in the adjacent normal tissue, adenomas, primary tumor and the metastatic CRC (all P<0.05). Furthermore, EYA2 expression had significant associations with disease stage, differentiation grade, and number of resected lymph nodes (all P<0.001). Compared with patients with EYA2-high tumors, those with EYA2-low tumors had shorter disease-free survival (hazard ratio [HR], 2.347; 95% CI, 1.665–3.308) and disease-specific survival (HR, 3.560; 95% CI, 2.055–6.167) in multivariate Cox analysis, after adjusting confounding factors such as tumor-node-metastasis stage and grade. In particular, patients with stage II or III EYA2-low CRC might be harmed by postoperative chemotherapy. Conclusion: EYA2 expression was generally reduced in CRC. Higher EYA2 expression can predict a more favorable prognosis for CRC. Keywords: colorectal cancer, EYA2, immunohistochemistry, prognosis, chemotherapy