Suchergebnisse

Acknowledgements We would like to acknowledge Prof. Joe Eustace, consultant nephrologist, for facilitating data collection in the renal outpatient clinic and for assisting in re-wording the outcomes for the patient document. Thank you also to Ellen Murphy, who assisted in data collection at two clinics. The Health Services Research Unit, University of Aberdeen, receives core funding from the Chief Scientist Office of the Scottish Government Health Directorates. Funding There was no direct funding received for this research. The HRB CRF-C at UCC facilitated the placement of an undergraduate pharmacy student, DB, who participated in the nephrology study. ; Peer reviewed ; Publisher PDF

Funding statement Some of the work described was part of Chief Scientist Office (CSO) grant CZH/4/773 and UK Medical Research Council and the University of Dundee through the provision of a PhD stipend for Kirsty Loudon, the University of Stirling and from the Health Services Research Unit at the University of Aberdeen, Nursing Midwifery Allied Health Professionals Research Unit at the University of Stirling which are both core funded by the CSO of the Scottish Government Health Directories. Stephanie Taylor was (in part) supported by the National Institute for Health Research (NIHR) Collaboration for Leadership in Applied Health Research and Care (CLAHRC) North Thames at Bart's Health NHS Trust. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health ; Peer reviewed ; Postprint

Acknowledgements We would like to thank our ActWELL participants who attended the events for their interest and enthusiasm in making the events a success. We would like to thank Susan MacAskill for giving us permission to use a quote from her email to us. We are also grateful to the technical support who got us through all events, Cormac Staunton (of stauntonmedia.ie). We would also like to acknowledge and thank Dr Katie Gillies and Dr Seonaidh Cotton for their contribution to the design of the evaluation survey. HSRU is core funded by the Chief Scientist Office of the Scottish Government Health and Social Care Directorates. This work was supported by The Scottish Government, grant number BC/ Screening/17/01. ; Peer reviewed ; Publisher PDF

Funding: KG was supported by an MRC Methodology Research Fellowship (MR/L01193X/1). The views and opinions expressed therein are those of the authors and do not necessarily reflect those of the MRC. PRW was funded by the MRC North West Hub for Trials Methodology Research (MR/K025635/1) and the MRC/NIHR Trials Methodology Research Partnership (MR/S014357/1). The Health Services Research Unit is core-funded by the Chief Scientist Office of the Scottish Government Health and Social Care Directorates (CZU/3/3). Acknowledgements: The ELICIT Study team would like to thank Cynthia Fraser for help with developing and running the search strategies for the literature review, the DelphiManager team for all their support and guidance on the use of the Delphi platform, Health Services Research Unit Patient Involvement Group critical review of the Delphi questionnaire before dissemination, Heather Bagley for further comments on the Delphi questionnaire and also for dissemination of the survey information and link to a range of patient facing organisations, and to Beverley Smith for her assistance in organising the consensus meeting. We would also like to thank all participants of the study (including interview participants, Delphi respondents, and consensus meeting members) and organisations who disseminated the survey. Data Sharing: Data from the systematic review and Delphi survey phases of work are available from the corresponding author on request. ; Peer reviewed ; Publisher PDF

ACKNOWLEDGEMENTS We would like to thank all patients and sites that participated in the ScotCap evaluation. Funding Information: This study was funded by the Scottish Government which had no role in the study design, data collection, analysis or interpretation of results, or writing of this report. We would like to thank all patients and sites that participated in the ScotCap evaluation. Publisher Copyright: © 2021 Association of Coloproctology of Great Britain and Ireland. ; Peer reviewed ; Publisher PDF

We thank Jackie Caldwell, Iain Bishop, Grant Wyper, Kjersti Fergusson, and Martyn Ritchie in NHS National Services Scotland Information Services Division and all members of the Advisory Group for their contribution. Funding: The study was funded by Scottish Government Chief Scientist Office project grant CZH/3/17. The funder of the study had no role in study design, data collection, data analysis, data interpretation, or the writing of the report. The corresponding author had full access to all the data in the study and had final responsibility for the decision to submit for publication. ST works at the Health Services Research Unit, University of Aberdeen, which is funded by the Chief Scientist Office of the Scottish Government Health Directorates. ; Peer reviewed ; Publisher PDF

This work was supported by the Chief Scientist Office (CSO) of Scotland grant CZH/4/773, the UK Medical Research Council and the University of Dundee work through the provision of a stipend for KL and from the Health Services Research Unit at the University of Aberdeen, which is core funded by the CSO of the Scottish Government Health Directories. We are grateful to all the participants who assisted in this study: F Althabe, A-W Chan, D Altman, D Bratton, E Brass, M Campbell, G Forbes, B Gaglio, R Glasgow, H Hobbelen, S Hopewell, J Krishnan, D Riddle, J Segal, D Steinfort, P Tugwell, SN Van der Veer, VA. Welch, C Witt. ; Peer reviewed ; Postprint

Funding The original study was funded by the Chief Scientist Office, grant number CZH/4/610. The analyses reported here were funded by a Medical Research Council Doctoral Training Grant awarded to the first author. The Health Services Research Unit, University of Aberdeen, is core funded by the Chief Scientist Office of the Scottish Government Health Directorates. The funding sources had no role in the study design; the collection, analysis, or interpretation of data; the writing of the report; or in the decision to submit the article for publication ; Peer reviewed ; Postprint

We acknowledge the host trial teams, and specifically members who were involved in the implementation of this SWAT. These include Sally Baker, Katie Banister, Zoe Batham, Suzanne Breeman, Patrycja Bromm, Emma Brookes, Becky Bruce, Louise Campbell, Seonaidh Cotton, Janice Cruden, Tracey Davidson, Dianne Dejean, Charlotte Diamond, Anne Duncan, Maddy Elliot, Elerita Flammini, Mark Forrest, Andrea Fraser, Pauline Garden, Sue Heslop, Kalpita Joshi, Amy Marshall, Dawn McRae, Alex Mitchell, Maria Ntessalen, Tanya Pawson, Lyn Robinson-Smith, Lesley Sinclair, Kath Starr, Bev Smith, Brian Taylor, Puvan Tharmanathan, Charlie Welch, and Sharon Wren. Additionally, we acknowledge the HSRU Patient and Public Involvement Group, which contributed to the Christmas card design Funding: This study within a trial (SWAT) was funded by the PROMETHEUS MRC programme grant (MR/R013748/1). Each host trial received its own funding. C-Gall, DISC, FUTURE, ProFHER-2, PUrE, REFLECT, and SWHSI-2 were funded by the National Institute for Health Research Health Technology Assessment Programme. CPIT-3 was funded by Cancer Research UK, the Chief Scientist Office, Scottish Government, HSC Public Health Agency NI, Chest Heart and Stroke NI, The Lullaby Trust, Public Health Agency NI, and the Scottish Cot Death Trust. The Health Services Research Unit (HSRU) is core funded by the Chief Scientist Office of the Scottish Government Health and Social Care Directorate. The funders (MRC) had no role in considering the study design or in the collection, analysis, or interpretation of the data; the writing of the report; or the decision to submit the article for publication. ; Peer reviewed ; Publisher PDF

Acknowledgements We would like to thank all of the participants who volunteered their time to contribute to this study. We would also like to thank all of the teams linked to the host trials we worked with to help identify potential participants. Funding This research is funded by the Chief Scientist Office of the Scottish Government's Health and Social Care Department [HIPS/16/46]. KG held a Medical Research Council UK Methodology Fellowship during the delivery of this project [MR/L01193X/1]. The publication was supported through a Health Research Board Trials Methodology Research Network award. MDW acknowledges support from the NIHR Newcastle Biomedical Research Centre. MW acknowledges support from the NIHR Imperial Biomedical Research Centre (BRC). The Health Services Research Unit, Institute of Applied Health Sciences (University of Aberdeen), is core-funded by the Chief Scientist Office of the Scottish Government Health and Social Care Directorates. The funders had no involvement in study design, collection, analysis and interpretation of data, reporting or the decision to publish. ; Peer reviewed ; Publisher PDF

Acknowledgements The authors would like to acknowledge the assistance of Amy Hickman, and Eluned Hughes from Breast Cancer Now, for guidance on practical intervention perspectives, and Jill Hampton in manuscript preparation. Thanks also to all the members of our public advisory group. The Health Services Research Unit, University of Aberdeen, receives core funding from Scottish Government Chief Scientist Office. Funding This work was supported by The Scottish Government, grant number BC/Screening/17/01. The funders provided independent referee reports, which guided some of the study parameters (as described in the text). The funders have read this manuscript. In-kind support was given by Breast Cancer Now for facilitating this study. ; Peer reviewed ; Publisher PDF

Acknowledgements and funding We would like to thank the GPs who took part in this study. We would also like to thank Marie Pitkethly and Gail Morrison for their help and support in recruiting GPs to the study. WIME was funded by the Chief Scientist Office, grant number CZH/4/610. The Health Services Research Unit, University of Aberdeen, is core funded by the Chief Scientist Office of the Scottish Government Health Directorates. ; Peer reviewed ; Postprint

Acknowledgements The Health Services Research Unit at the University of Aberdeen receives core funding from the Chief Scientist Office of the Scottish Government Health Directorates. Funding This work has received funding from the National Institute for Health Research (NIHR) INCLUDE initiative led from the Newcastle University CRN Cluster Office, NIHR Senior Investigator funding provided to PB and the UK Research Innovation-Medical Research Council COVID-19 Rapid Response funding (grant MR/V020544/1). MDW acknowledges support from the NIHR Newcastle Biomedical Research Centre. ; Peer reviewed ; Publisher PDF

Acknowledgments We would like to thank all of the participants who volunteered and gave up their time to contribute to this study. We would also like to thank all of the teams linked to the host trials we worked with to help identify potential participants. Funding This research is funded by the Chief Scientist Office of the Scottish Government's Health and Social Care Depart- ment [HIPS/16/46]. KG held a Medical Research Council UK Methodology Fellowship during the delivery of this project [MR/L01193X/1]. MDW acknowledges support from the NIHR Newcastle Biomedical Research Centre. Infrastructure support for this research was provided by the NIHR Imperial Biomedical Research Centre (BRC) to support MW. The Health Services Research Unit, Institute of Applied Health Sciences (University of Aberdeen), is core-funded by the Chief Scientist Office of the Scottish Government Health and Social Care Directorates. The funders had no involvement in study design, collection, analysis and interpretation of data, reporting or the decision to publish. ; Peer reviewed ; Publisher PDF

Background: The prevalence of male obesity is increasing but few men take part in weight loss programmes. We assessed the effect of a weight loss and healthy living programme on weight loss in football (soccer) fans. Methods: We did a two-group, pragmatic, randomised controlled trial of 747 male football fans aged 35-65 years with a body-mass index (BMI) of 28 kg/m2 or higher from 13 Scottish professional football clubs. Participants were randomly assigned with SAS (version 9·2, block size 2-9) in a 1:1 ratio, stratified by club, to a weight loss programme delivered by community coaching staff in 12 sessions held every week. The intervention group started a weight loss programme within 3 weeks, and the comparison group were put on a 12 month waiting list. All participants received a weight management booklet. Primary outcome was mean difference in weight loss between groups at 12 months, expressed as absolute weight and a percentage of their baseline weight. Primary outcome assessment was masked. Analyses were based on intention to treat. The trial is registered with Current Controlled Trials, number ISRCTN32677491. Findings: 374 men were allocated to the intervention group and 374 to the comparison group. 333 (89%) of the intervention group and 355 (95%) of the comparison group completed 12 month assessments. At 12 months the mean difference in weight loss between groups, adjusted for baseline weight and club, was 4·94 kg (95% CI 3·95-5·94) and percentage weight loss, similarly adjusted, was 4·36% (3·64-5·08), both in favour of the intervention (p<0·0001). Eight serious adverse events were reported, five in the intervention group (lost consciousness due to drugs for pre-existing angina, gallbladder removal, hospital admission with suspected heart attack, ruptured gut, and ruptured Achilles tendon) and three in the comparison group (transient ischaemic attack, and two deaths). Of these, two adverse events were reported as related to participation in the programme (gallbladder removal and ruptured Achilles tendon). Interpretation: The FFIT programme can help a large proportion of men to lose a clinically important amount of weight; it offers one effective strategy to challenge male obesity. Funding: Scottish Government and The UK Football Pools funded delivery of the programme through a grant to the Scottish Premier League Trust. The National Institute for Health Research Public Health Research Programme funded the assessment (09/3010/06). © 2014 Hunt et al.