Suchergebnisse

Approximately 4-11% of children suffer from sleep-disordered breathing (SDB), and children with obesity are at increased risk. Both obesity and SDB have been separately associated with poorer brain health, yet whether SDB severity affects brain health in children with obesity remains unanswered. This study aimed to examine associations of SDB severity with academic performance and brain structure (i.e., total brain and gray and white matter volumes and gray matter volume in the hippocampus) in children with overweight/obesity. One hundred nine children aged 8-12 years with overweight/obesity were included. SDB severity and its subscales (i.e., snoring, daytime sleepiness, and inattention/hyperactivity) were evaluated via the Pediatric Sleep Questionnaire (PSQ), and academic performance was evaluated with the Woodcock-Munoz standardized test and school grades. Brain structure was assessed by magnetic resonance imaging. SDB severity was not associated with academic performance measured by the standardized test (all vertical bar beta vertical bar> 0.160, P > 0.076), yet it was associated with the school grade point average (beta = -0.226, P = 0.007) and natural and social science grades (beta = -0.269, P = 0.024). Intention/hyperactivity seemed to drive these associations. No associations were found between SDB severity and the remaining school grades (all beta 0.065) or brain volumes (all P > 0.05). Conclusion: Our study shows that SDB severity was associated with lower school grades, yet it was not associated with the standardized measurement of academic performance or with brain volumes in children with overweight/obesity. SDB severity may add to academic problems in children beyond the effects contributed by overweight/obesity status alone. ; Funding Agencies|Universidad de Granada/CBUA; Spanish Ministry of Economy and CompetitivenessSpanish Government; Fondo Europeo de Desarrollo Regional (FEDER)European CommissionSpanish Government [DEP201347540, DEP2016-79512-R, DEP2017-91544-EXP, RYC-201109011]; Spanish Ministry of Science, Innovation and UniversitiesSpanish Government [FPU17/04802]; Spanish Ministry of Education, Culture and SportSpanish Government [FPU15/02645]; Spanish Ministry of Science and InnovationSpanish Government [FJC2018-037925-I, RYC2019-027287-I]; University of Granada, Plan Propio de Investigacion 2016, Excellence actions: Units of Excellence, Scientific Excellence Unit on Exercise and Health (UCEES); Junta de Andalucia, Consejeria de Conocimiento, Investigacion y UniversidadesJunta de Andalucia; European Regional Development FundsEuropean Commission [SOMM17/6107/UGR]; SAMID III network, RETICS - PNI + D + I 2017-2021 (Spain); ISCIII-Sub-Directorate General for Research Assessment and Promotion; European Regional Development Fund (ERDF)European Commission [RD16/0022]; EXERNET Research Network on Exercise and Health [DEP2005-00046/ACTI, 09/UPB/19, 45/UPB/20, 27/UPB/21]; European UnionEuropean Commission [667302]; HL-PIVOT network-Healthy Living for Pandemic Event Protection; Andalusian Operational Programme; European Regional Development Funds (ERDF in English, FEDER in Spanish) [B-CTS-355-UGR18]