Open Access#12010
Changing epidemiology of human parvovirus 4 infection in sub-Saharan Africa
Sharp, Colin P; Vermeulen, Marion; Nébié, Yacouba; Djoko, Cyrille F; LeBreton, Matthew; Tamoufe, Ubald; Rimoin, Anne W; Kayembe, Patrick K
Sharp, Colin P; Vermeulen, Marion; Nébié, Yacouba; Djoko, Cyrille F; LeBreton, Matthew; Tamoufe, Ubald; Rimoin, Anne W; Kayembe, Patrick K; Carr, Jean K; Servant-Delmas, Annabelle; Laperche, Syria; Harrison, GL Abby; Pybus, Oliver G; Delwart, Eric; Wolfe, Nathan D; Saville, Andrew; Lefrère, Jean Jacques; Simmonds, Peter
Human parvovirus 4 infections are primarily associated with parenteral exposure in western countries. By ELISA, we demonstrate frequent seropositivity for antibody to parvovirus 4 viral protein 2 among adult populations throughout sub-Saharan Africa (Burkina Faso, 37%; Cameroon, 25%; Democratic Republic of the Congo, 35%; South Africa, 20%), which implies existence of alternative transmission routes.