Suchergebnisse

El presente artículo pretende una aproximación al sistema de comunicación que emplea el sector público de vivienda en Venezuela, con la población objetivo que le es pertinente. Esta se hace desde la perspectiva futurista con el fin de explorar el universo de posibilidades a desarrollar en este campo. En este sentido, se caracterizan las organizaciones emergentes y se esboza la comunicación que el sector público tiene actualmente con su población a la par que se plantea una nueva manera de comunicación que contribuya a lograr los objetivos del sector. El fundamento del trabajo fue una revisión estrictamente bibliográfica que permite concluir que la comunicación actual es unidireccional y restringida.

Este trabajo presenta una visión general de la actividad que en el campo educativo ha desarrollado la radio enAmérica Latina, destacando el modelo puesto en práctica porACPOen Sutatenza, Colombia, imitado por otras emisoras católicas latinoamericanas que posteriormente se constituyeron en el eje fundamental para la creación de la Asociación Latinoamérica de EducaciónRadiofónica, ALER, convertida hoy en el sistema satelital más importante de América y del cual forma parte el Instituto Radiofónico Fe y Alegría (IRFA), organismo que con su red de emisoras, ha llevado adelante una serie de estrategias comunicacionales que le han servido para enfrentar los retos y exigencias de su acción en la educación popular. Para lograr el objetivo propuesto se hizo una revisión de varios investigadores que se han dedicado al estudio de este tema, entre los que se cuentan Lewis y Booth, Bernal, Figueroa, Geerts y Van Oeyen, García, O"™Sullivan y Correa. Los resultados permiten concluir que ha sido muy importante la labor de las emisoras para la educación en América Latina.

Este artículo constituye un adelanto de investigación de los aspectos teóricos sobre la relación del sujeto productor que hace uso de las Tecnologías de la Información y la Comunicación (TIC"™s), y en especial de la radio multimedia, para conectarse con el usuario oyente, y establecer interacciones comunicativas a distancia. El trabajo se sustenta en el análisis cualitativo de los conceptos de midiación de Muniz Sodré; de comunidades de comunicación de Galindo Cáceres y de globalización de Mato y Colina; para ofrecer desde la perspectiva postmoderna de Lyotard, cuál es el rol del sujeto contemporáneo que se vincula con los demás a través de la radio multimedia, para conformar un espacio de alteridad mediada. Metodológicamente, trabajamos con Vassalo de Lopes y la visión transdiciplinaria sugerida por Pineda.

Background: Mobile phone health apps are increasingly gaining attention in oncological care as potential tools for supporting cancer patients. Although the number of publications and health apps focusing on cancer is increasing, there are still few specifically designed for the most prevalent cancers diagnosed: breast and prostate cancers. There is a need to review the effect of these apps on breast and prostate cancer patients' quality of life (QoL) and well-being. Objective: The purposes of this study were to review the scientific literature on mobile phone apps targeting breast or prostate cancer patients and involving QoL and well-being (anxiety and depression symptoms) and analyze the clinical and technological characteristics, strengths, and weaknesses of these apps, as well as patients' user experience with them. Methods: We conducted a systematic review of peer-reviewed literature from The Cochrane Library, Excerpta Medica Database, PsycINFO, PubMed, Scopus, and MEDLINE to identify studies involving apps focused on breast and/or prostate cancer patients and QoL and/or well-being published between January 1, 2000, and July 12, 2017. Only trial studies which met the inclusion criteria were selected. The systematic review was completed with a critical analysis of the apps previously identified in the health literature research that were available from the official app stores. Results: The systematic review of the literature yielded 3862 articles. After removal of duplicates, 3229 remained and were evaluated on the basis of title and abstract. Of these, 3211 were discarded as not meeting the inclusion criteria, and 18 records were selected for full text screening. Finally, 5 citations were included in this review, with a total of 644 patients, mean age 52.16 years. Four studies targeted breast cancer patients and 1 focused on prostate cancer patients. Four studies referred to apps that assessed QoL. Only 1 among the 5 analyzed apps was available from the official app store. In 3 studies, an app-related intervention was carried out, and 2 of them reported an improvement on QoL. The lengths of the app-related interventions varied from 4 to 12 weeks. Because 2 of the studies only tracked use of the app, no effect on QoL or well-being was found. Conclusions: Despite the existence of hundreds of studies involving cancer-focused mobile phone apps, there is a lack of rigorous trials regarding the QoL and/or well-being assessment in breast and/or prostate cancer patients. A strong and collective effort should be made by all health care providers to determine those cancer-focused apps that effectively represent useful, accurate, and reliable tools for cancer patients' disease management. ; European Union's Horizon 2020 No 722012

Oncolytic virotherapy represents a promising alternative for cancer treatment; however, viral delivery to the tumor represents a major challenge. Mesenchymal stem cells (MSCs) chemotax to tumors, and can serve as a viral delivery tool. Previously, we demonstrated antitumor therapeutic efficacy for mesenchymal stem cells (MSCs) infected with the oncolytic human adenovirus ICOVIR5 (Celyvir) for treatment of neuroblastoma patients. Given the lack of suitable immunocompetent preclinical models, the mechanism underlying Celyvir antitumor activity remains unknown. In this study, we used the syngeneic murine CMT64 cell line as a human adenovirus-semi-permissive tumor model and demonstrate the homing capacity of mouse Celyvir (mCelyvir) to CMT64 tumors. We found that the combined treatment of mCelyvir and intratumoral injections (i.t.) of ICOVIR5 was more effective than treatment with i.t. ICOVIR5 alone. Interestingly, the superior therapeutic effect of the combined therapy was associated with a higher tumor infiltration of CD8+ and CD4+ T cells. Our findings suggest that the use of MSCs as carriers of oncolytic adenovirus can improve the clinical efficacy of anti-cancer virotherapy, not only by driving the adenovirus to tumors, but also through their potential to recruit T cells. ; This work was supported by grants from the Fondo de Investigaciones Sanitarias (PI05/2217; PI08/0029; PI14CIII/00005), RTICC (RD12/0036/0015; RD12/0036/0027) and the Madrid Regional Government (S-BIO-0204-2006, MesenCAM; P2010/BMD-2420, CellCAM) in Spain to JG-C. ER and TC are supported by the "Sara Borrell" program of the Instituto de Salud Carlos III. The experiments were approved by the appropriate committees. ; Sí