Gene-expression profiling of breast cells purified with laser microdissection: identification of genes associated with tumor development
In: Zentralblatt für Gynäkologie, Band 127, Heft 4
ISSN: 1438-9762
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In: Zentralblatt für Gynäkologie, Band 127, Heft 4
ISSN: 1438-9762
In: Zentralblatt für Gynäkologie, Band 122, Heft 9, S. 476-482
ISSN: 1438-9762
In: Zentralblatt für Gynäkologie, Band 126, Heft 4, S. 275-279
ISSN: 1438-9762
In: Zentralblatt für Gynäkologie, Band 122, Heft 10, S. 514-518
ISSN: 1438-9762
In: Zentralblatt für Gynäkologie, Band 127, Heft 3
ISSN: 1438-9762
The Patient Reported Outcomes Measurement System (PROMIS) offers standardized assessment measures of clinically relevant patient reported outcomes. This study evaluated the reliability and validity of select PROMIS measures with United States Military Veterans following orthopedic surgery. Data for the current study were collected as part of a pilot randomized control trial assessing the efficacy of a one day Acceptance and Commitment Therapy workshop on persistent post-surgical pain in at-risk Veterans undergoing orthopedic surgery. Sixty-seven participants completed surveys three months after surgery. Participants completed the following PROMIS instruments: PROMIS Anxiety Short Form 8a, PROMIS Depression Short Form 8b, and PROMIS pain interference short form 8a. PROMIS measures were compared to the Generalized Anxiety Disorder 7-item scale (GAD-7), the Patient Health Questionnaire 9-item scale (PHQ-9), and the Brief Pain Inventory (BPI) pain interference subscale (respectively). All three PROMIS measures demonstrated excellent internal consistency (Cronbach's alphas ranged from .93 - .96) and each loaded onto a single factor. The PROMIS measures were moderately correlated with their respective comparison measures (r = .69 - .76). The PROMIS anxiety and PROMIS depression measures were highly correlated to one another (r = .91). Findings highlight the potential utility of these PROMIS measures in Veterans following orthopedic surgery and the overlap between the PROMIS depression and anxiety measures in this sample.
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