Suchergebnisse

Part-1: Concepts, definitions and historical perspectives -- Chapter-01: Defining, re-defining, and understanding the brain and mental health during ageing -- Chapter-02: Social, historical and anthropological aspects of research on the brain and ental health in aging -- Chapter-03: Understanding hormesis for optimizing brain health -- Part-2: Biological modulators of the ageing brain -- Chapter-04: Dietary constituents for mental health promotion and healthy ageing -- Chapter-05: Physical activity and dietary interventions for mental health in ageing and longevity -- Chapter-06: Immunity, immunosenescence, brain and cognitive/mental health -- Chapter-07 Neurovirology and Brain Health – A Microglial Perspective -- Chapter-08: Gut microbiota-brain axis in healthy aging -- Chapter-09: Connexin-mediated nuroglial gap Junction communication: Unravelling its significance in brain health and aging -- Chapter-10: Maintenance of mitochondrial dynamics for healthy brain aging -- Part-3: Brain health maintenance, promotion and recovery in ageing -- Chapter-11: Phytochemicals and vitagenes for a healthy brain -- Chapter-12: Infection, neuroinflammation and interventions for healthy brain and longevity -- Chapter-13: Nutraceuticals as an intervention for healthy brain aging -- Chapter-14: Pharmacological interventions for maintaining brain health in ageing -- Chapter-15: Sleep and circadian rhythms as modulators of mental health in Ageing -- Part-4: Mental health maintenance, promotion and recovery in ageing -- Chapter-16: The impact of psychopathology and psychological well-being on cognitive health -- Chapter-17: The neuroscience of positive emotions and gratitude in healthy ageing and longevity -- Chapter-18: Cognitive profiles across normal and unhealthy ageing -- Chapter-19: Sleep and Mental Health in the Aging Population -- Chapter-20: Brain health of women beyond middle age: hormonal and non-hormonal perspective -- Chapter-21: Psychobiotics: a restorative intervention for lifestyle-induced deteriorations of mental health -- Chapter-22: Autism and ADHD in old age -- Chapter-23: Epigenetic regulation of age-associated neuropsychiatric disorders.

Dietary proteins: functions and health benefits -- Fats and oils in healthy ageing and longevity -- Micronutrients in ageing and longevity -- Prebiotics and probiotics in ageing and longevity -- Nutritional hormetins in ageing and longevity -- Nutritional regulation of ageing and longevity (Alexey Moskalev, Moscow Institute of Physics and Technology -- Animal- and plant-based food for health and longevity (AzzaSilotry Naik, Food BioSciences Department, Teagasc Food Research Centre. .

This book argues that a narrow policy on successful ageing excludes a large portion of ageing individuals from the quest for a good life in old age. It explores various models defining successful ageing and argues that successful ageing in guiding policy will profit by following a pluralistic and holistic view.

Human longevity continues to increase world-wide, often accompanied by decreasing birth rates. As a larger fraction of the population thus gets older, the number of people suffering from disease or disability increases dramatically, presenting a major societal challenge. Healthy ageing has therefore been selected by EU policy makers as an important priority ; it benefits not only the elderly but also their direct environment and broader society, as well as the economy. The theme of healthy ageing figures prominently in the Horizon 2020 programme , which has launched several research and innovation actions (RIA), like "Understanding health, ageing and disease: determinants, risk factors and pathways" in the work programme on "Personalising healthcare". Here we present our research proposal entitled "ageing with elegans" (AwE), funded by this RIA, which aims for better understanding of the factors causing health and disease in ageing, and to develop evidence-based prevention, diagnostic, therapeutic and other strategies. The aim of this article, authored by the principal investigators of the 17 collaborating teams, is to describe briefly the rationale, aims, strategies and work packages of AwE for the purposes of sharing our ideas and plans with the biogerontological community in order to invite scientific feedback, suggestions, and criticism. ; Peer reviewed