Chapter 1. A Brilliant Chapter in the Fight against Poverty: China's Road -- Chapter 2. The Evolution and Historical Mission of Anti-Poverty in China -- Chapter 3. China's Anti-poverty: Exploration since the 18th CPC National Congress -- Chapter 4. China's Anti-poverty Experience: Economic Growth and Regional Equilibrium -- Chapter 5. China's Experience in Anti-poverty: Industrial Development and Ecological Protection -- Chapter 6. China's Experience in Combating Poverty: Culture, Education and Guarantee Mechanism.
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In: World development: the multi-disciplinary international journal devoted to the study and promotion of world development, Band 26, Heft 8, S. 1413-1429
We investigated the mediating effect of trait self-control in the relationship between Internet altruistic behavior (IAB) and subjective well-being (SWB) in Chinese adolescents. Participants were 179 boys and 236 girls (N = 415), who completed the Internet Altruistic Behavior Scale, the Chinese Self-Control Scale, and the Index of Well-Being in one sitting. The correlation analysis results reveal that IAB had a positive correlation with trait self-control and SWB, trait self-control was positively correlated with SWB, and the combined effect of IAB and trait self-control positively affected SWB. Additionally, IAB had an indirect positive effect on SWB via trait self-control, which indicates that trait self-control partially mediated the relationship between IAB and SWB. These results offer insight into the underlying mechanisms of how IAB may promote SWB in adolescents.
In: Ecotoxicology and environmental safety: EES ; official journal of the International Society of Ecotoxicology and Environmental safety, Band 209, S. 111800
Abstract Endometriosis (EMS) is an estrogen-dependent disease. However, little is known about the regulation of estrogen, a potential therapeutic target, in EMS, which remains very poorly managed in the clinic. We hypothesized that microRNAs (miRNAs) can be exploited therapeutically to regulate transcription factor 21 (TCF21) and steroidogenic factor-1 (SF-1) gene expression. In our study, paired eutopic and ectopic endometrial samples were obtained from women with EMS and processed by a standard protocol to obtain human endometrial stromal cells (EMs) for in vitro studies. We found that miR-92a-3p levels were decreased in ectopic endometrium and ectopic stromal cells (ESCs) compared with paired eutopic lesions. miR-92a-3p overexpression significantly suppressed the proliferation and migration of ESCs, whereas a decreased level of miR-92a-3p generated the opposite results. Next, we identified TCF21 as a candidate target gene of miR-92a-3p. In vitro cell experiments showed that miR-92a-3p negatively regulated the expression of TCF21 and its downstream target gene SF-1. Moreover, cell proliferation and invasion ability decreased after the silencing of SF-1 and increased after SF-1 overexpression. We also observed that silencing SF-1 while inhibiting miR-92a-3p partially blocked the increase in cell proliferation and invasion ability caused by miR-92a-3p knockdown while overexpressing both SF-1 and miR-92a-3p mitigated the impairment in cell proliferation and invasion ability caused by miR-92a-3p overexpression. Our results may provide a novel potential therapeutic target for the treatment of EMS.
