A bioelectronic sensor based on canine olfactory nanovesicle-carbon nanotube hybrid structures for the fast assessment of food quality
We developed an olfactory-nanovesicle-fused carbon-nanotube-transistor biosensor (OCB) that mimics the responses of a canine nose for the sensitive and selective detection of hexanal, an indicator of the oxidation of food. OCBs allowed us to detect hexanal down to 1 fM concentration in real-time. Significantly, we demonstrated the detection of hexanal with an excellent selectivity capable of discriminating hexanal from analogous compounds such as pentanal, heptanal, and octanal. Furthermore, we successfully detected hexanal in spoiled milk without any pretreatment processes. Considering these results, our sensor platform should offer a new method for the assessment of food quality and contribute to the development of portable sensing devices. ; This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MEST) (2011-0000390) and the Conversing Research Center Program (2011K000683). SH acknowledges the support from the NBIT program (2011-00240) and the NRF grant (2011-0020984). THP thanks the support from the NRF grant (no. 2011-0000331, 2011K000682, and 2011-0020984). ; OAIID:oai:osos.snu.ac.kr:snu2012-01/102/0000002410/12 ; SEQ:12 ; PERF_CD:SNU2012-01 ; EVAL_ITEM_CD:102 ; USER_ID:0000002410 ; ADJUST_YN:Y ; EMP_ID:A002014 ; DEPT_CD:458 ; CITE_RATE:4.23 ; DEPT_NM:화학생물공학부 ; EMAIL:thpark@snu.ac.kr ; SCOPUS_YN:N ; CONFIRM:Y