Open Science calls for transparent science and involvement of various stakeholders. Here are examples of and advice for meaningful stakeholder engagement. ; Ana Lúcia Mena was funded by the Portuguese Foundation for Science and Technology—FCT. The Soy-in-1000-gardens project and the Liver project were funded within the Grand Challenges Program of VIB. This VIB Program received support from the Flemish Government under the Management Agreement 2017–2021 (VR 2016 2312 Doc.1521/4). Inês Pinheiro funded by ANR LabEx DEEP (11-LBX-0044, ANR-10-IDEX-0001-02) and by Institut Curie. We acknowledge support of the Spanish Ministry of Science and Innovation to the EMBL partnership, the Centro de Excelencia Severo Ochoa and the CERCA Programme/Generalitat de Catalunya. We acknowledge funding from European Commission (EC): 741527
In: Auffray , C , Balling , R , Barroso , I , Bencze , L , Benson , M , Bergeron , J , Bernal-Delgado , E , Blomberg , N , Bock , C , Conesa , A , Del Signore , S , Delogne , C , Devilee , P , Di Meglio , A , Eijkemans , M , Flicek , P , Graf , N , Grimm , V , Guchelaar , H J , Guo , Y K , Gut , I G , Hanbury , A , Hanif , S , Hilgers , R D , Honrado , Á , Hose , D R , Houwing-Duistermaat , J , Hubbard , T , Janacek , S H , Karanikas , H , Kievits , T , Kohler , M , Kremer , A , Lanfear , J , Lengauer , T , Maes , E , Meert , T , Müller , W , Nickel , D , Oledzki , P , Pedersen , B , Petkovic , M , Pliakos , K , Rattray , M , i Màs , J R , Schneider , R , Sengstag , T , Serra-Picamal , X , Spek , W , Vaas , L A I , van Batenburg , O , Vandelaer , M , Varnai , P , Villoslada , P , Vizcaíno , J A , Wubbe , J P M & Zanetti , G 2016 , ' Making sense of big data in health research : Towards an EU action plan ' , Genome medicine , vol. 8 , no. 1 , 71 . https://doi.org/10.1186/s13073-016-0323-y
Medicine and healthcare are undergoing profound changes. Whole-genome sequencing and high-resolution imaging technologies are key drivers of this rapid and crucial transformation. Technological innovation combined with automation and miniaturization has triggered an explosion in data production that will soon reach exabyte proportions. How are we going to deal with this exponential increase in data production? The potential of "big data" for improving health is enormous but, at the same time, we face a wide range of challenges to overcome urgently. Europe is very proud of its cultural diversity; however, exploitation of the data made available through advances in genomic medicine, imaging, and a wide range of mobile health applications or connected devices is hampered by numerous historical, technical, legal, and political barriers. European health systems and databases are diverse and fragmented. There is a lack of harmonization of data formats, processing, analysis, and data transfer, which leads to incompatibilities and lost opportunities. Legal frameworks for data sharing are evolving. Clinicians, researchers, and citizens need improved methods, tools, and training to generate, analyze, and query data effectively. Addressing these barriers will contribute to creating the European Single Market for health, which will improve health and healthcare for all Europeans.
Medicine and healthcare are undergoing profound changes. Whole-genome sequencing and high-resolution imaging technologies are key drivers of this rapid and crucial transformation. Technological innovation combined with automation and miniaturization has triggered an explosion in data production that will soon reach exabyte proportions. How are we going to deal with this exponential increase in data production? The potential of "big data" for improving health is enormous but, at the same time, we face a wide range of challenges to overcome urgently. Europe is very proud of its cultural diversity; however, exploitation of the data made available through advances in genomic medicine, imaging, and a wide range of mobile health applications or connected devices is hampered by numerous historical, technical, legal, and political barriers. European health systems and databases are diverse and fragmented. There is a lack of harmonization of data formats, processing, analysis, and data transfer, which leads to incompatibilities and lost opportunities. Legal frameworks for data sharing are evolving. Clinicians, researchers, and citizens need improved methods, tools, and training to generate, analyze, and query data effectively. Addressing these barriers will contribute to creating the European Single Market for health, which will improve health and healthcare for all Europeans.
In: Auffray , C , Balling , R , Barroso , I , Bencze , L , Benson , M , Bergeron , J , Bernal-Delgado , E , Blomberg , N , Bock , C , Conesa , A , Del Signore , S , Delogne , C , Devilee , P , Di Meglio , A , Eijkemans , M , Flicek , P , Graf , N , Grimm , V , Guchelaar , H-J , Guo , Y-K , Gut , I G , Hanbury , A , Hanif , S , Hilgers , R-D , Honrado , Á , Hose , D R , Houwing-Duistermaat , J , Hubbard , T , Janacek , S H , Karanikas , H , Kievits , T , Kohler , M , Kremer , A , Lanfear , J , Lengauer , T , Maes , E , Meert , T , Müller , W , Nickel , D , Oledzki , P , Pedersen , B , Petkovic , M , Pliakos , K , Rattray , M , I Màs , J R , Schneider , R , Sengstag , T , Serra-Picamal , X , Spek , W , Vaas , L A I , van Batenburg , O , Vandelaer , M , Varnai , P , Villoslada , P , Vizcaíno , J A , Wubbe , J P M & Zanetti , G 2016 , ' Making sense of big data in health research : Towards an EU action plan ' Genome Medicine , vol 8 , no. 1 , pp. 71 . DOI:10.1186/s13073-016-0323-y
Medicine and healthcare are undergoing profound changes. Whole-genome sequencing and high-resolution imaging technologies are key drivers of this rapid and crucial transformation. Technological innovation combined with automation and miniaturization has triggered an explosion in data production that will soon reach exabyte proportions. How are we going to deal with this exponential increase in data production? The potential of "big data" for improving health is enormous but, at the same time, we face a wide range of challenges to overcome urgently. Europe is very proud of its cultural diversity; however, exploitation of the data made available through advances in genomic medicine, imaging, and a wide range of mobile health applications or connected devices is hampered by numerous historical, technical, legal, and political barriers. European health systems and databases are diverse and fragmented. There is a lack of harmonization of data formats, processing, analysis, and data transfer, which leads to incompatibilities and lost opportunities. Legal frameworks for data sharing are evolving. Clinicians, researchers, and citizens need improved methods, tools, and training to generate, analyze, and query data effectively. Addressing these barriers will contribute to creating the European Single Market for health, which will improve health and healthcare for all Europeans.
In: Auffray , C , Balling , R , Barroso , I , Bencze , L , Benson , M , Bergeron , J , Bernal-Delgado , E , Blomberg , N , Bock , C , Conesa , A , Del Signore , S , Delogne , C , Devilee , P , Di Meglio , A , Eijkemans , M , Flicek , P , Graf , N , Grimm , V , Guchelaar , H J , Guo , Y K , Gut , I G , Hanbury , A , Hanif , S , Hilgers , R D , Honrado , Á , Hose , D R , Houwing-Duistermaat , J , Hubbard , T , Janacek , S H , Karanikas , H , Kievits , T , Kohler , M , Kremer , A , Lanfear , J , Lengauer , T , Maes , E , Meert , T , Müller , W , Nickel , D , Oledzki , P , Pedersen , B , Petkovic , M , Pliakos , K , Rattray , M , i Màs , J R , Schneider , R , Sengstag , T , Serra-Picamal , X , Spek , W , Vaas , L A I , van Batenburg , O , Vandelaer , M , Varnai , P , Villoslada , P , Vizcaíno , J A , Wubbe , J P M & Zanetti , G 2016 , ' Erratum to : Making sense of big data in health research: Towards an EU action plan [Genome Med., 8 (2016) (71)] ' , Genome medicine , vol. 8 , no. 1 , 118 . https://doi.org/10.1186/s13073-016-0376-y
The published article [1] has two points of confusion in the section entitled "Technical challenges related to the management of electronic health records". Firstly, the International Rare Diseases Research Consortium (IRDiRC) has developed policies and guidelines on approaches to data sharing meant to enable and improve the development of diagnoses and therapies for rare diseases. However, at present, IRDiRC has not developed best practices for the management of electronic health records (EHRs). Secondly, RARE-Bestpractices is a European Commission 7th Framework Programme (FP7) funded initiative, independent of IRDiRC. RARE-Bestpractices contributes to IRDiRC goals and objectives; however the initiative itself is not sponsored nor connected to IRDiRC.
Medicine and healthcare are undergoing profound changes. Whole-genome sequencing and high-resolution imaging technologies are key drivers of this rapid and crucial transformation. Technological innovation combined with automation and miniaturization has triggered an explosion in data production that will soon reach exabyte proportions. How are we going to deal with this exponential increase in data production? The potential of "big data" for improving health is enormous but, at the same time, we face a wide range of challenges to overcome urgently. Europe is very proud of its cultural diversity; however, exploitation of the data made available through advances in genomic medicine, imaging, and a wide range of mobile health applications or connected devices is hampered by numerous historical, technical, legal, and political barriers. European health systems and databases are diverse and fragmented. There is a lack of harmonization of data formats, processing, analysis, and data transfer, which leads to incompatibilities and lost opportunities. Legal frameworks for data sharing are evolving. Clinicians, researchers, and citizens need improved methods, tools, and training to generate, analyze, and query data effectively. Addressing these barriers will contribute to creating the European Single Market for health, which will improve health and healthcare for all Europeans.
