Risk Factors for Regrowth of Intracranial Meningiomas after Gamma Knife Radiosurgery: Importance of the Histopathological Grade and MIB-1 Index
In: Minimally invasive neurosurgery, Band 52, Heft 5/06, S. 216-221
ISSN: 1439-2291
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In: Minimally invasive neurosurgery, Band 52, Heft 5/06, S. 216-221
ISSN: 1439-2291
In: Minimally invasive neurosurgery, Band 51, Heft 3, S. 140-146
ISSN: 1439-2291
Optimal management of cavernous sinus hemangiomas remains unclear. Total microsurgical removal of these neoplasms may be extremely difficult due to their rich vascularization. Three cases of cavernous sinus hemangioma treated with low-dose Gamma Knife radiosurgery are presented. Marginal dose varied from 10 to 13 Gy. Treatment planning and radiation dosimetry were done with a goal of conformal and selective coverage of the lesion with 50% prescription isodose line using multiisocenter technique. In all cases significant shrinkage of the neoplasm was marked at 3 months after treatment. Mean volume reduction at 12 months after radiosurgery was 60% (range: 45-75%). In all patients the shrinkage of the neoplasm was accompanied by notable improvement of the preexistent oculomotor nerve palsy. No radiosurgery-related complications were met during follow-up. In conclusion, low-dose Gamma Knife radiosurgery seems to be very effective for management of cavernous sinus hemangiomas, and can be considered as a treatment modality of choice for these lesions.
In: Minimally invasive neurosurgery, Band 50, Heft 4, S. 233-238
ISSN: 1439-2291