Suchergebnisse

This study aimed to carry out a retrospective study of vagal indigestion cases diagnosed in cattle admitted at the Garanhuns Bovine Clinic, Federal Rural University of Pernambuco campus. This syndrome, caused by dysfunctions of the vagus nerve and characterized by motility disorders of the pre-stomachs and abomasum, represented 5.5% (70/1279) of digestive cases diagnosed in a period of 10 years and had an unfavorable prognosis in 78.3% of cases. Type II vagal indigestion was the most prevalent, accounting for 40% of cases, followed by type I (24.3%) and types III and IV, which accounted for 18.6% and 10.0% of cases, respectively. Vagal indigestion in 67.1% (47/70) of cases occurred as a result of other illnesses, such as traumatic reticuloperitonitis (27.7%), lung diseases (12.8%), gastric impaction (10.6%), abomasal ulcer (10.6%), lymphosarcoma (6.4%), and liver abscesses (6.4%). Motor changes in the gastrointestinal tract, such as hypomotility, abdominal distension, and bloat, as well as their consequences, were the most frequent clinical signs. Laboratory, ultrasonographic, and anatomopathological alterations mainly originate from the primary illnesses present in each case. The approach of this disease is essential due to its clinical and economic importance for livestock to expand the knowledge of its etiopathogenesis, thus contributing to a more accurate diagnosis by veterinarians working in the field of internal medicine for cattle.

The increase in energy imbalance at the beginning of lactation leads to metabolic disorders, especially clinical ketosis, in highly productive dairy cows. The objective of this study is to evaluate the clinical characteristics, biochemical parameters, and cardiac biomarkers creatine kinase MB isoenzyme (CK-MB) and cardiac troponin I (cTnI) of 15 cows diagnosed with clinical ketosis treated at the Bovine Clinic of Garanhuns at the Federal Rural University of Pernambuco. Nine of the 15 cows were diagnosed with primary ketosis and six had concomitant diseases, including left abomasal displacement, metritis, pneumonia, and renal failure. The observed clinical signs were non-specific and included decreased appetite and milk production and weight loss. Approximately 53% of the animals had central nervous system involvement. For biochemical evaluation, 15 high-production healthy dairy cows at the initial stage of lactation served as the control group. The data were subjected to analysis of variance for simultaneous comparison between two means allowing testing the hypothesis on the means of the different groups and subjected to Pearson correlation at a level of significance of 5%. The levels of ?-hydroxybutyrate (BHB), non-esterified fatty acids (NEFA), glucose, fructosamine, total protein, albumin, creatinine, aspartate aminotransferase, creatine kinase, CK-MB, and cTnI were higher in the group with ketosis. The diseased animals presented changes in glycemia, reduction in tissue sensitivity to insulin, and a lower RQUICKI-BHB index, especially hyperglycemic animals. The increase in the levels of cardiac biomarkers suggests the occurrence of myocardial injury associated with bovine ketosis.

This study aimed to evaluate the hematologic response and the serum and peritoneal fluid (PF) proteinogram of cattle affected by digestive diseases. Twenty-seven animals were distributed in two groups: GI (intestinal diseases) and GII (traumatic reticuloperitonitis, TRP). The animals were previously submitted to a physical exam. Subsequently, blood samples were collected to perform the complete blood count, determine the plasma protein and fibrinogen, and obtain the serum for proteinogram in polyacrylamide gel (SDS-PAGE). Simultaneously, PF was collected to perform physical and chemical evaluation and the electrophoretic profile (SDS-PAGE). ANOVA at the 5% probability level was used to compare the groups. The animals showed signs of apathy, dehydration, and gastrointestinal hypomotility in both groups. However, GI animals showed more significant clinical changes. The blood count of both groups (P > 0.05) showed leukocytosis due to neutrophilia and a regenerative left shift with hyperfibrinogenemia. The proteinogram of both body fluids allowed the identification of proteins albumin (ALB), transferrin (TRF), ceruloplasmin, haptoglobin, ?1-acid glycoprotein (?1-AGP), MW 23000 Da, ?1-antitrypsin, IgA, and IgG. The [PT] PF/[PT] blood serum ratio of each of the identified proteins increased, showing statistical differences between groups (P < 0.05) regarding PT, ALB, TRF, ?1-AGP, and IgG values, with GI animals showing the highest ratio. Intestinal diseases and TRP triggered a systemic and local response characterized by clinical, hematological, and serum and PF proteinogram alterations. The proteins ?1-GPA, haptoglobin, and TRF measured in PF were good inflammation biomarkers and useful as an auxiliary tool for the diagnosis and prognosis of digestive diseases in cattle.