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Electric vehicles (EVs) have the advantages of low pollution, low energy consumption, and high energy efficiency, so they are highly valued by governments, enterprises, and consumers. However, the promotion and use of electric vehicles is restricted to a certain extent because of their limited range. This paper selects electric vehicle intercity medium- and long-distance travel as the research object, and takes the classical flow-capturing location problem as the theoretical basis for the expressway network or national highway network. This paper also considers the driver's charging choice behavior and range anxiety, studies the electric vehicle charging station location problem, establishes the charging station location model, and uses the Tabu search algorithm to solve the problem. Finally, the effectiveness of the model and algorithm is verified by empirical analysis. The results show that the charging station location model considering the driver's charging choice behavior and range anxiety performs better.

"With digital media becoming ever more prevalent, it is essential to study policy and marketing strategies tailored to this new development. In this volume, contributors examine government policy for a range of media, including digital television, IPTV, mobile TV, and OTT TV. They also address marketing strategies that can harness the unique nature of digital media's innovation, production design, and accessibility. They draw on case studies in Asia, North America, and Europe to offer best practices for both policy and marketing strategies"--Publisher's description

Pharmacogenomics is research to study the drug treatment responses in subgroups of patients according to their genetic variants or genetic expression information. Methadone maintenance treatment, which is usually prescribed for patients with heroin dependence, was launched in Taiwan by the government in 2006. In this study, 366 patients who had taken methadone continually in the previous 7 days were examined. Data from administration of the Treatment Outcomes Profile (TOP), Severity of Dependence Scale (SDS), Clinical Opioid Withdrawal Scale (COWS), and Treatment Emergent Symptoms Scale (TESS) were obtained from patients' report records. Genes encoding the liver cytochrome P-450 (CYP) enzymes that are involved with the metabolism of methadone (CYP2B6, 3A4 and 2C19) were selected and genotyped in this cohort. We found that the SNPs on CYP2B6 were associated with plasma S-methadone concentration; SNPs on CYP3A4 were associated with withdrawal symptoms and side effects; and SNPs on CYP2C19 were associated with methadone dose. SNPs in the genes encoding the morphine phase II metabolic enzyme, UGT2B7, were associated with withdrawal symptom scores. In pharmacodynamic genes, the SNPs on OPRM1 were associated with insomnia and change in libido side effects. We conclude that SNP markers may be useful for future methadone dosage adjustment and to reduce adverse reactions.