Suchergebnisse

TaiNan Lin,1 Ling Su,2 JinHua Lin,1 Hong Qiu1 1Department of Ophthalmology, Fujian Provincial Governmental Hospital, Fuzhou, People's Republic of China; 2School Health Department, Fujian Center for Disease Control and Prevention, Fuzhou, People's Republic of ChinaCorrespondence: TaiNan LinDepartment of Ophthalmology, Fujian Provincial Governmental Hospital, No. 67 of Gupin Street, Gulou District, Fuzhou, 350003, People's Republic of ChinaTel +86 591 88013047Fax +86 591 88013003Email lintainandr@163.comObjective: The present study aims to observe the optic nerve fiber layer thickness and blood flow density in the papillary area and investigate the effects of axial length (AL) and the refractive state of the optic papilla blood flow density in children with different refractive conditions.Methods: The present study was a clinical control study. The right eyes of 204 minors aged 6– 17 years were studied. The eyes were divided into four groups according to myopic refractive states. OCTA analyzed the data to compare the radial peripapillary capillary (RPC) density and the difference in the retinal nerve fiber layer (RNFL) thickness adjacent to the optic papilla between the four refraction groups.Results: The intra-optic disc blood flow density was significantly and negatively correlated with the AL and was negatively correlated with the AL in the inferior temporal quadrants. The RNFL in the superior, nasal, and inferior quadrants was negatively correlated with the AL. The RNFL in the temporal quadrant was positively correlated with the AL.Conclusion: Our present study revealed that aAs myopia increased and the AL grew in children, the blood density of the entire image of the optic papilla, in the optic disc, and the retinal capillaries in the inferior parapapillary and temporal quadrant would change significantly. With increasing AL, a significant decrease in the intra-disc and para-disc RNFL was observed in the superior, nasal, and inferior quadrants, while a substantial increase in RNFL was observed in the temporal quadrant.Keywords: myopic, optic nerve, fiber layer, blood flow, OCTA

TaiNan Lin,1,* Yan Yang,2,* JinHua Lin,1 JiHui Zhang,1 Qian Wen,1 XiaoLu He,1 GuoQing Chen1 1Department of Ophthalmology, Fujian Provincial Governmental Hospital, Fuzhou, 350003, People's Republic of China; 2Fujian Center for Disease Control and Prevention, Fuzhou, 350001, People's Republic of China*These authors contributed equally to this workCorrespondence: TaiNan LinDepartment of Ophthalmology, Fujian Provincial Governmental Hospital, No. 67 of Gupin Street, Gulou District, Fuzhou, 350003, People's Republic of ChinaTel +86 591 88013047Fax +86 591 88013003Email lintainandr@163.comObjective: This study aimed to compare the macular and choroidal thicknesses and blood-flow parameters of patients with intermediate and simple juvenile moderate myopia in order to provide a greater understanding of the pathogenesis of myopia and a basis for its prevention.Methods: Participants were selected from patients under the age of 18 with moderate myopia who were treated in our ophthalmic clinic between June and December 2019. Seventy-five right eyes were selected from participants with a mean spherical equivalent ranging from − 6.0 to − 3.0 D. These samples were divided into two groups based on eye axial length (AL). The thicknesses of the macula and choroid, the area of the foveal avascular zone (FAZ), and the blood flow density of the macular capillaries were measured, intergroup comparison was conducted.Results: The average area of the FAZ was larger in the intermediate group than in the simple group. PERIM in the upper half was lower in the intermediate group than in the simple group, and the blood-flow density in the lower half of the macular area was higher in the simple group than in the intermediate group. The blood-flow density within 1 mm of the fovea centralis and the downward blood-flow density were higher in the intermediate group than in the simple group. The thicknesses of the lower part of the FAZ, the choroid of the fovea centralis, and the choroid under the retina were all larger in the intermediate group than in the simple group.Conclusion: The area of the FAZ in patients with intermediate juvenile moderate myopia is larger than that in patients with simple myopia; the choroid in the fovea of macula compensatorily increases, and blood flow density also increases; the thickness of the choroid under the retina increases with myopia.Keywords: choroidal blood flow, choroidal thickness, myopic adolescents, moderate myopia, optical coherence tomography angiography