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This longitudinal study explored how the relationship-building behavior of new employees induces career success. First, we proposed and tested a model based on mentoring and social capital theories, using mentor tie strength as a mediator to explain the association between relationship-building behavior and career success (career satisfaction and promotion). Next, we examined the moderating role of social network density and the moderated mediation effect. Survey data were collected at two time points from 252 new employees of a Chinese company. The results indicate that mentor tie strength mediated the association between relationship-building behavior and subjective career success (career satisfaction), and that social network density moderated the relationship between mentor tie strength and career satisfaction. Further, mentor tie strength mediated the association between relationship-building behavior and subjective career success (career satisfaction) when social network density was low; however, the mediation effect was nonsignificant when social network density was high. We discuss the theoretical and practical implications.

PurposeDrawing on social exchange theory and a cultural perspective, this study examines the relationship between workplace ostracism and job engagement by focusing on the mediating role of felt obligation and the moderating role of collectivism.Design/methodology/approachA two-wave survey was conducted over four months in a private service business in China. The participants comprised 108 Chinese employees.FindingsThe results indicate that workplace ostracism has a negative relationship with job engagement through a reduced sense of felt obligation. Collectivism strengthens the main effect of workplace ostracism on felt obligation and its indirect effect on job engagement via felt obligation.Research limitations/implicationsThis study contributes to understanding of the internal mechanism of the workplace ostracism–job engagement model by identifying the mediating role of felt obligation. It also emphasizes that collectivist cultures can enhance the effects of workplace ostracism. However, the generalizability of our findings may be limited due to this cultural factor.Practical implicationsOur findings show that workplace ostracism plays a significant role in reducing job engagement. Therefore, it is essential to reduce the incidence of ostracism in the workplace.Originality/valueBy addressing the previously unexplored mechanism that mediates the relationship between workplace ostracism and job engagement, this study provides new directions for research on workplace ostracism and job engagement.

Wheat beer would be a desirable source of quality soluble dietary fibre (SDF). The effects of wort preparing parameters on SDF in wheat beer were investigated in the present work. Non-starch polysaccharides and polyphenols were greatly influenced by wheat malt percentage (WMP), while resistant protein (RP) was augmented by extending resting at 63°C. By verification test, the optimised parameters for high SDF wheat beer were WMP 55%, resting for 20 min at 43°C, 20 min at 50°C, and 20 min at 63°C, in which SDF was 2,178 mg/L. Most of SDF in wheat wort were retained in beer during fermentation and maturation (R = 0.561*). And SDF of wheat beer contained more RP and polyphenols. The present work contributes in controlling SDF content in wheat beer. It also has important guiding significance for beer brewing enterprises to develop new products rich in SDF.

<b><i>Objective:</i></b> Accumulated evidence suggests that ATP-binding cassette A1 transporter (ABCA1) contributes to secreting insulin in pancreatic β-cells and amyloid beta formation. This study aimed to investigate the association between three single nucleotide polymorphisms (SNPs) of ABCA1 and susceptibility to type 2 diabetes mellitus (T2DM) in a Han Chinese population. <b><i>Methods:</i></b> A total of 996 T2DM patients and 1,002 controls were included in the study. Three SNPs in the <i>ABCA1</i> gene, i.e., rs2230806 (R219K), rs1800977 (C69T), and rs9282541 (R230C), were genotyped by SNaPshot. A genotype model, an allele model, a dominant model, and a recessive model were used to assess susceptibility to T2DM. <b><i>Results:</i></b> There were significant associations between rs1800977 and T2DM in different genetic models (TT vs. CC, OR = 0.591 [0.446–0.793], <i>p</i> &#x3c; 0.001; T vs. C, OR = 0.835 [0.735–0.949], <i>p</i> = 0.006; recessive model, OR = 0.583 [0.449–0.756], <i>p</i> &#x3c; 0.001). There were also significant associations between rs9282541 and T2DM in different genetic models (CT vs. CC, OR = 1.690 [0.807–1.005], <i>p</i> = 0.048; T vs. C, OR = 1.756 [0.694–1.060], <i>p</i> = 0.029; dominant model, OR = 1.735 [0.715–1.034], <i>p</i> = 0.037). <b><i>Conclusion:</i></b> Our case-control study showed that the two SNPs rs1800977 and rs9282541 in the <i>ABCA1</i> gene are significantly associated with susceptibility to T2DM in our Han Chinese population. Study of further mechanisms should be performed before application to clinical therapy.

BACKGROUND: Myopia is the most common visual impairment in children and adolescents worldwide. This study described an economical and effective population-based screening pipeline and performed the project of a million scale children and adolescents myopia survey (CAMS), which will shed light on the further study of myopia from the level of epidemiology and precision medicine. METHODS: We developed a novel population-based screening pattern, an intelligent screening process and internet-based information transmission and analysis system to carry out the survey consisting of school children in Wenzhou, China. The examination items include unaided distance visual acuity, presenting distance visual acuity, and non-cycloplegic autorefraction. Myopia and high myopia were defined as spherical equivalent (SE) ≤ − 1.00 diopters (D) and SE ≤ − 6.00 D, respectively. Next, the reports of the vision checking were automatically sent to parents and the related departments. The CAMS project will be done two to four times annually with the support of the government. An online eyesight status information management system (OESIMS) was developed to construct comprehensive and efficient electronic vision health records (EVHRs) for myopia information inquiry, risk pre-warning, and further study. RESULTS: The CAMS completed the first-round of screening within 30 days for 99.41% of Wenzhou students from districts and counties, in June 2019. A total of 1,060,925 participants were eligible for CAMS and 1,054,251 (99.37% participation rate) were selected through data quality control, which comprised 1305 schools, and 580,609, 251,050 and 170,967 elementary, middle, and high school students. The mean age of participants was 12.21 ± 3.32 years (6–20 years), the female-to-male ratio was 0.82. The prevalence of myopia in elementary, middle, and high school students was 38.16%, 77.52%, and 84.00%, respectively, and the high myopia incidence was 0.95%, 6.90%, and 12.98%. CONCLUSIONS: The CAMS standardized myopia screening model involves ...