The relevance of the article is substantiated by the development of intercultural competence which is assumed to be the required quality for military personnel nowadays.The article considers the analysis of features and prospects of "dialogue of cultures" educational approach application through the intercultural competence development among military students of higher military educational institutions in the course of foreign language training. The concept of dialogue and its role in the development of foreign language and intercultural competence is defined. The necessity to develop the dialogic speech competence with the use of other cultures interaction is substantiated.The article analyzes the basic principles of "dialogue of cultures" approach, which were established in the late 20th century based on the ideas of dialogue of cultures school by the philosopher B. Bibler. The article elicits a number of modern teaching approaches, which in combination with the technology of "dialogue of cultures" will help to form the necessary competencies of cadets of higher military educational institutions for professional communication. The algorithm of introduction of technology of "dialogue of cultures" provided in four stages is offered: diagnostics of readiness of cadets for communication, search of motivating factors, application of system of exercises for communicative interaction between cadets in the form of dialogue, providing feedback.It was found that the use of "dialogue of cultures" approach promotes developing a number of key competencies, i.e. the development of speech skills and critical thinking, the ability to search for information and use it in the speech, the enhancement of teamwork skills, and training through dialogue. Such competencies development is the condition to form intercultural competence, which enables servicemen to solve their professional tasks, as they affect the formation of cultural policy during international communication with representatives of various strata of society.
The relevance of the article is substantiated by the development of intercultural competence which is assumed to be the required quality for military personnel nowadays.The article considers the analysis of features and prospects of "dialogue of cultures" educational approach application through the intercultural competence development among military students of higher military educational institutions in the course of foreign language training. The concept of dialogue and its role in the development of foreign language and intercultural competence is defined. The necessity to develop the dialogic speech competence with the use of other cultures interaction is substantiated.The article analyzes the basic principles of "dialogue of cultures" approach, which were established in the late 20th century based on the ideas of dialogue of cultures school by the philosopher B. Bibler. The article elicits a number of modern teaching approaches, which in combination with the technology of "dialogue of cultures" will help to form the necessary competencies of cadets of higher military educational institutions for professional communication. The algorithm of introduction of technology of "dialogue of cultures" provided in four stages is offered: diagnostics of readiness of cadets for communication, search of motivating factors, application of system of exercises for communicative interaction between cadets in the form of dialogue, providing feedback.It was found that the use of "dialogue of cultures" approach promotes developing a number of key competencies, i.e. the development of speech skills and critical thinking, the ability to search for information and use it in the speech, the enhancement of teamwork skills, and training through dialogue. Such competencies development is the condition to form intercultural competence, which enables servicemen to solve their professional tasks, as they affect the formation of cultural policy during international communication with representatives of various strata of society.
Присвячено аналізові стану реформування фінансової системи України в частині ефективного функціонування місцевої влади. Установлено, що, незважаючи на законодавче закріплення відповідних повноважень, невирішеними залишаються питання фінансової децентралізації. Потребує подальшого розвитку методологія вирівнювання податкоспроможності територій в умовах трансформації державних ресурсів. Визначено, що для удосконалення фінансового забезпечення видаткових повноважень, які передані місцевому самоврядуванню, слід переглянути нормативи відрахувань до місцевих бюджетів.Доцільним є перегляд методики розрахунку і використання коштів освітньої та медичної субвенцій. Установлено, що розподіл обсягу цих субвенцій між місцевими бюджетами повинен ураховувати чисельність населення внаслідок змін в адміністративно-територіальному устрої окремих територій за рішенням Верховної Ради України, а також кількість внутрішньо переміщених осіб із територій, на яких тимчасово не здійснюються повноваження органів державної влади. Доведено, що розширенню можливостей органів місцевого самоврядування сприятиме запровадження нового механізму розрахунку горизонтального вирівнювання місцевих бюджетів, згідно з яким реверсна дотація визначалася за групами бюджетів: окремо за бюджетами міст обласного значення, окремо за зведеними бюджетами районів та окремо за бюджетами об'єднаних територіальних громад.Запропоновано створити оптимальний перелік повноважень місцевого самоврядування, упорядкувати обсяги видатків на виконання повноважень, які передаються на місцевий рівень. Це сприятиме забезпеченню стабільності міжбюджетних відносин, удосконаленню системи оподаткування, позитивно вплине на фінансову спроможність місцевого самоврядування і надасть можливість зміцнити їхню ресурсну базу. ; The article is devoted to the analysis of the state of reforming the financial system of Ukraine in terms of effective functioning of local authorities. It is established that, despite the legislative consolidation of the certain powers, the issues of financial decentralization remain unsolved. Further development of the methodology of equalizing the tax capacity of territories in the conditions of transformation of state resources is needed. It is determined that in order to improve the financial support of the expenditure capacity transferred to local self-government bodies, it is necessary to revise the rates of deductions to local budgets. It is advised to review the methodology for calculating and using educational and medical subventions. It was found out that during distribution of the volume of these subventions between local budgets one must take into account the quantity of population as a result of changes in the administrative and territorial structure of certain areas by the decision of the Verkhovna Rada of Ukraine, as well as the number of internally displaced persons from territories where the powers of state authorities are temporarily not carried out. It is proved that the extension of capacities of local self-government bodies will be facilitated by the introduction of a new mechanism for calculating the horizontal alignment of local budgets, according to which the reverse subsidy is allocated by groups of budgets: separately for budgets of regional cities, separately for consolidated budgets of districts and separately for budgets of united territorial communities. It is proposed to create an optimal list of powers of local self-government, to organize the volume of expenditures for the implementation of powers transferred to the local level. This will promote stability of inter-budgetary relations, improve the taxation system, have a positive impact on the financial capacity of local self-government and will provide an opportunity to strengthen their resource base. ; Посвящено анализу состояния реформирования финансовой системы Украины в части эффективного функционирования местной власти. Установлено, что, несмотря на законодательное закрепление соответствующих полномочий, нерешенными остаются вопросы финансовой децентрализации. Требует дальнейшего развития методология выравнивания налогоспособности территорий в условиях трансформации государственных ресурсов. Определено, что для совершенствования финансового обеспечения расходных полномочий, переданных местному самоуправлению, следует пересмотреть нормативы отчислений в местные бюджеты. Доказано, что расширению возможностей органов местного самоуправления будет способствовать введение нового механизма расчета горизонтального выравнивания местных бюджетов. Предложено создать оптимальный перечень полномочий местного самоуправления, упорядочить объемы расходов на выполнение полномочий, которые передаются на местный уровень. Это будет способствовать обеспечению стабильности межбюджетных отношений, совершенствованию системы налогообложения, положительно повлияет на финансовую состоятельность местного самоуправления и позволит укрепить их ресурсную базу.
Human beta-defensins (hBDs) are small cationic antimicrobial peptides with multiple biologic activities. The aim of the study was cloning, expression in E.coli, purification and in vitro analysis of biological activity of recombinant human beta-defensin-3 (rec-hBD-3). hBD-3 cDNA was cloned into pGEX-2T vector, and recombinant plasmid was transformed into E.coli BL21(DE3) cells. Rec-hBD-3 was expressed in bacterial cells as GST-hBD-3 fusion protein, and purified by 3-step procedure via affine chromatography on glutathione-agarose, cleavage of fusion protein by thrombin, and reverse phase chromatography on Sep-Pack C18. Analysis of biological activity of rec-hBD-3 has shown that the peptide is active against Pseudomonas aeruginosa in micromolar concentrations in radial diffusion test. Rec-hBD-3 did not affect proliferation and viability of cultured human cancer cells of A431, A549, and TPC-1 lines, but was capable to potentiate cytotoxic effects of rec-hBD-2 and docetaxel in vitro.
The method of complex surface hardening of steel detailswas designed. The method is a compound of two processes of hardening: chemical heat treatment and physical vapor deposition (PVD) of the coating. The result, achieved in this study is much higher, than in other work on this topic and is cumulative. The method designed can be used in mechanical engineering, medicine, energetics and is perspective for military and space technologies. ; Разработан способ комплексного поверхностного упрочнения стальных изделий, представляющий собой сочетание двух методик упрочнения: химико-термической обработки и нанесения PVD-покрытия. Достигнутый в результате эффект значительно превосходит известные аналоги и является кумулятивным. Способ может использоваться в машиностроении, медицине, энергетике, перспективен для военной и космической техники.
