Suchergebnisse

Researcher: Kanak K Khan, Suman Chib. Presentation Title: Opinion of students of Lovely Professional University on Hijab Controversy. Research Focus: Social and Ethics. The Karnataka High Court has taken up the case of Muslim women students at a Government College in the town of Udupi who were denied access into their class because they wore Hijab, a head scarf, a covering to which they were accustomed. Initially, there were just six of these kids, but their numbers grew exponentially over time. They did not revolt suddenly; this was a practice that other female members of their families were also used to, and they just followed after understanding that it was part of their faith and belief. Despite students' protests, the college management relented on its decision to prohibit hijab in government college classrooms. They and their parents argued with college officials that it is their constitutional right to dress according to their religious practice. The educational institution cited a government directive mandating all students to wear a set uniform, and hijab is not part of the uniform. Resham, a student, sought the Karnataka High Court to seek redress, and three other students joined in the case known as Resham v State of Karnataka and Ors. As a result, the case is presently in court. We have all heard the negative and positive comments delivered by some well known politicians and other dignitaries. As we all know that Lovely Professional University has a diversity of students studying from different states and countries. This project is based on what do students of LPU think about the ongoing hot topic of the Hijab Controversy.

Abstract
Extracellular vesicles (EVs) transfer bioactive molecules between cells in a process reminiscent of enveloped viruses. EV cargo delivery is thought to occur by protein-mediated and pH-dependent membrane fusion of the EV and the cellular membrane. However, there is a lack of methods to identify the fusion proteins and resolve their mechanism. We developed and benchmarked an in vitro biophysical assay to investigate EV membrane fusion. The assay was standardized by directly comparing EV and viral fusion with liposomes. We show that EVs and retroviruses fuse with liposomes mimicking the membrane composition of the late endosome in a pH- and protein-dependent manner. Moreover, we directly visualize the stages of membrane fusion using cryo-electron tomography. We find that, unlike most retroviruses, EVs remain fusogenic after acidification and reneutralization. These results provide novel insights into the EV cargo delivery mechanism and an experimental approach to identify the EV fusion machinery.