Infectious Diseases in Solid-Organ Transplant Recipients: A Practical Approach
Intro -- Contents -- Part I: General Transplant Infectious Diseases -- 1: The Epidemiology of Infection in Solid Organ Transplant Recipients: A Practical Timeline -- 1.1 Definitions and Concepts -- 1.2 Timetable of Infections -- 1.3 Period 1: Transplantation to 30 Days -- 1.4 Period 2: 1 Month Posttransplant to 12 Months Posttransplant -- 1.5 Period 3: Beyond 12 Months -- 1.6 Assessment and Management of a Recipient with Suspected Infection -- 1.7 Recent Changes in the Timeline -- 1.8 Current Challenges and Future Developments -- 1.9 Conclusion -- References -- 2: Risk Assessment of Infections in SOT Recipients -- 2.1 Introduction -- 2.2 Time from Transplant -- 2.3 Pre-transplant Recipient Factors -- 2.3.1 Donor Factors -- 2.3.2 Surgical Factors -- 2.4 Post-transplant Factors -- 2.4.1 Community and Healthcare-Associated Exposures -- 2.4.2 Net State of Immunosuppression -- 2.4.3 Strategies for Immune Monitoring -- 2.4.4 Antimicrobial Prophylaxis -- 2.4.5 Antirejection Therapy -- References -- 3: Pre- and Peri-transplant Period: Screening and Treatment of Infections in the Pretransplant Period, Donor-Derived Infection -- 3.1 Introduction -- 3.2 Definitions and Epidemiology -- 3.3 Timelines -- 3.4 Diagnosis and Screening -- 3.4.1 Clinical Screening -- 3.4.2 Required Donor Laboratory Screening -- 3.4.3 Geographically or Seasonally Limited Infections -- 3.5 General Approach -- 3.5.1 Bacterial Organisms -- 3.5.1.1 Routine Bacterial Infections -- 3.5.1.2 Multidrug-Resistant Bacteria -- 3.5.2 Fungal Organisms -- 3.5.2.1 Candida -- 3.5.2.2 Endemic Fungi and Cryptococcus -- 3.5.3 Environmental Molds -- 3.5.4 Mycobacteria -- 3.5.5 Viral Infections -- 3.5.5.1 Human Immunodeficiency Virus -- 3.5.5.2 Hepatitis B and Hepatitis C -- 3.5.5.3 Other Viruses -- 3.5.6 Selected Parasitic Infections.