Suchergebnisse

The introduction and analysis of a simple idealized model enables basic insights into how military characteristics and recruitment strategies affect the dynamics of armed conflicts, even in the complex case of three or more fighting groups. In particular, the model shows when never ending wars (stalemates) are possible and how initial conditions and interventions influence a conflict's fate. The analysis points out that defensive recruitment policies aimed at compensating for suffered losses lead to conflicts with simple dynamics, while attack groups sensitive to the damages they inflict onto their enemies can give rise to conflicts with turbulent behaviours. Since non-governmental groups often follow attack strategies, the conclusion is that the evolution of conflicts involving groups of that kind can be expected to be difficult to forecast.

The introduction and analysis of a simple idealized model enables basic insights into how military characteristics and recruitment strategies affect the dynamics of armed conflicts, even in the complex case of three or more fighting groups. In particular, the model shows when never ending wars (stalemates) are possible and how initial conditions and interventions influence a conflict's fate. The analysis points out that defensive recruitment policies aimed at compensating for suffered losses lead to conflicts with simple dynamics, while attack groups sensitive to the damages they inflict onto their enemies can give rise to conflicts with turbulent behaviours. Since non-governmental groups often follow attack strategies, the conclusion is that the evolution of conflicts involving groups of that kind can be expected to be difficult to forecast.

The introduction and analysis of a simple idealized model enables basic insights into how military characteristics and recruitment strategies affect the dynamics of armed conflicts, even in the complex case of three or more fighting groups. In particular, the model shows when never ending wars (stalemates) are possible and how initial conditions and interventions influence a conflict's fate. The analysis points out that defensive recruitment policies aimed at compensating for suffered losses lead to conflicts with simple dynamics, while attack groups sensitive to the damages they inflict onto their enemies can give rise to conflicts with turbulent behaviours. Since non-governmental groups often follow attack strategies, the conclusion is that the evolution of conflicts involving groups of that kind can be expected to be difficult to forecast.

The introduction and analysis of a simple idealized model enables basic insights into how military characteristics and recruitment strategies affect the dynamics of armed conflicts, even in the complex case of three or more fighting groups. In particular, the model shows when never ending wars (stalemates) are possible and how initial conditions and interventions influence a conflict's fate. The analysis points out that defensive recruitment policies aimed at compensating for suffered losses lead to conflicts with simple dynamics, while attack groups sensitive to the damages they inflict onto their enemies can give rise to conflicts with turbulent behaviours. Since non-governmental groups often follow attack strategies, the conclusion is that the evolution of conflicts involving groups of that kind can be expected to be difficult to forecast.

PURPOSE: To revise and systematize scientific knowledge of the experimental model for cutaneous burns in rats. METHODS: A bibliographical review from 2008 up to January 2011 in PubMed, EMBASE and LILACS was undertaken. Were used the keywords: animal models, burns and rats. 221 studies were identified, and 116 were selected. RESULTS: It was found that: 54/86 (62.7%) had third degree burns; 55/73 (75.3%) studied the back; 45/78 (57.6%) used heated water and 27/78 (35.9%) incandescent instruments; 39/78 (50%) studied systemic effects; 22/71 (31%) used ketamine associated with xylazine; 61/64 (95.3%) performed depilation with appropriate equipment; 36/72 (50%) used microscopy; more than 50% did not describe analgesia or antibiotics during the postoperative period; in 42/116 (36.2%) postoperative fluid therapy was performed; and the time interval after the burn, up to the beginning of the results analysis varied from 7s up to four weeks. Legislation issues on burn experiments are discussed. CONCLUSION: The hot water was the main method to induce burns those of third degree on the back, with anesthesia using ketamine and xylazine, after depilation. These were evaluated microscopically, without using analgesia or an antibiotic during the postoperative period. The studies were not very reproducible. ; OBJETIVO: Revisar e sistematizar o conhecimento científico do modelo experimental em queimadura da pele em ratos. MÉTODOS: Revisão da literatura foi realizada de 2008 a Janeiro de 2011 na PubMed, EMBASE e LILACS. Os descritores usados foram: modelo animal, queimadura e ratos. 221 estudos foram identificados e 116 foram selecionados. RESULTADOS: Foi encontrado que: 54/86 (62,7%) tinham queimadura de terceiro grau; 55/73 (75,3%) estudaram o dorso; 45/78 (57.6%) usaram líquido aquecido e 27/78 (35,9%) usaram instrumento incandescente; 39/78 (50%) estudaram efeitos sistêmicos; 22/71 (31%) usaram ketamina associada a xilazina; 61/64 (95,3%) realizaram depilação com equipamento apropriado; 36/72 (50%) usaram microscopia; mais de 50% não descreveram uso de analgésicos ou antibióticos durante o período pós-operatório; em 42/116 (36,2%) foi realizada reposição hídrica pós-operatória; e o intervalo de tempo após a queimadura e a análise variou de 7s a quatro semanas. Aspectos legais sobre experimentos em queimaduras foram discutidos. CONCLUSÃO: Líquido aquecido foi o principal método para induzir queimadura de terceiro grau no dorso do animal, com anestesia usando quetamina e xilazina, após depilação, avaliados por microscopia, sem uso de analgesia ou antibióticos. Os estudos não são reprodutíveis. ; UNIFESP-EPM ; UNIFESP, EPM ; SciELO