Suchergebnisse

El concepto de Constitución remite al estudio del Control Político. El problema del control político del Gobierno es la actual piedra angular de cualquier sistema de Gobierno. Este artículo rastrea el tema desde la Antigüedad hasta el Estado de Derecho, pasando por el medioevo, la edad moderna y la edad contemporánea. ; The concept of constitution sends to the study about the political control. The question of the government political control is, actually, the base of any government system. This article searches for the topic since the ancient times to the Entitlement State, passing across the middle age, the modern age and the contemporary age.

El concepto de Constitución remite al estudio del Control Político. El problema del control político del Gobierno es la actual piedra angular de cualquier sistema de Gobierno. Este artículo rastrea el tema desde la Antigüedad hasta el Estado de Derecho, pasando por el medioevo, la edad moderna y la edad contemporánea.The concept of constitution sends to the study about the political control. The question of the government political control is, actually, the base of any government system. This article searches for the topic since the ancient times to the Entitlement State, passing across the middle age, the modern age and the contemporary age.

SUMARIO: 1. INTRODUCCIÓN. 2. LA FUNCIÓN DE CONTROL DEL PARLAMENTO Y SU SUPUESTA CRISIS. 3. EL CONCEPTO «AMPLIO» DE CONTROL PARLAMENTARIO. 4. LA RACIONALIZACIÓN DEL PODER Y LA CIRCULACIÓN DE MODELOS COMO MEDIOS PARA LA REVALORACIÓN DEL CONTROL PARLAMENTARIO EN EL SISTEMA PRESIDENCIAL MEXICANO. 5. BREVES OBSERVACIONES METODOLÓGICAS PARA UNA OPERACIÓN DE TRANSPLANTE INSTITUCIONAL EN EL SISTEMA PRESIDENCIAL MEXICANO. 6. LÍMITES A LA REVALORACIÓN DEL CONTROL PARLAMENTARIO: LA INTANGIBILIDAD DE LAS FORMAS DE GOBIERNO. 7. A MODO DE CONCLUSIÓN. 8. BIBLIOGRAFÍA.

El presente artículo examina los alcances y límites que ha tenido la figura del matrimonio homosexual en el marco de los sistemas interamericano y europeo de derechos humanos en relación con el margen de apreciación nacional de sus Estados miembros, y cómo la Suprema Corte de Justicia de la Nación mexicana (SCJN) ha adoptado una doctrina de reconocimiento pleno a esa institución civil como un Derecho Humano y desplazando dicho margen en detrimento del principio democrático. La Corte mexicana ha sido quizá el único tribunal en el mundo en obligar a todos los Estados de la Federación a reconocer por la vía jurisprudencial la institución del matrimonio de forma igualitaria (matrimonio igualitario) lo cual ha planteado una serie de consecuencias teóricas difícilmente superables, además de una distorsión del principio democrático en México.

This paper analyzes constitutional scopes and limits about Same-Sex marriage in the frame of Interamerican and European Human Rights Systems regarding the margin of state discretion, and how Mexican Supreme Court has adopted full recognition of that civil institution as a human right shifting on democratic principle. Perhaps, this national Supreme Court has been almost the only Court in the world that recognizes in its jurisprudence Same-Sex marriage based on equal protection clause. Therefore, it has proposed several theoretical consequences hardly to overcome. Besides that situation, it had also modified the scope of the constitutional democratic principles in México. ; El presente artículo examina los alcances y límites que ha tenido la figura del matrimonio homosexual en el marco de los sistemas interamericano y europeo de derechos humanos en relación con el margen de apreciación nacional de sus Estados miembros, y cómo la Suprema Corte de Justicia de la Nación mexicana (SCJN) ha adoptado una doctrina de reconocimiento pleno a esa institución civil como un Derecho Humano y desplazando dicho margen en detrimento del principio democrático. La Corte mexicana ha sido quizá el único tribunal en el mundo en obligar a todos los Estados de la Federación a reconocer por la vía jurisprudencial la institución del matrimonio de forma igualitaria (matrimonio igualitario) lo cual ha planteado una serie de consecuencias teóricas difícilmente superables, además de una distorsión del principio democrático en México.

Producción Científica ; Hydrophilic composites of poly (acrylamide-co-2-hydroxyethyl methacrylate) reinforced with hydroxyapatite were synthesized, characterized and evaluated as drug delivery systems. The results show a strong dependence of the polymer composition, the degree of crosslinking and the homogeneity of the particles dispersion (filler or the mixed drug) in the characteristics that were analyzed. The mechanical properties were better while the swelling and the diffusion coefficient were worse than hydrogels with cefazolin of similar compositions. Additionally, a new information criterion was used to elucidate the best fit. The drug diffusion into the medium was anomalous with a tendency towards Case II transport, indicating that under certain conditions zero-order diffusion could be achieved. This fact suggests that these materials could be used in the manufacture of medical devices for the controlled delivery of drugs and active or biological principles, significantly improving therapeutic procedures today. ; 2020-12-06 ; 2020-12-06 ; European Union (Erasmus PLUS project NL01-KA 107-008639; Erasmus MUNDUS LINDO ML14PD1157)

Producción Científica ; Cartilage diseases currently affect a high percentage of the world's population. Almost all of these diseases, such as osteoarthritis (OA), cause inflammation of this soft tissue. However, this could be controlled with biomaterials that act as an anti-inflammatory delivery system, capable of dosing these drugs over time in a specific area. The objective of this study was to incorporate etanercept (ETA) into porous three-layer scaffolds to decrease the inflammatory process in this soft tissue. ETA is a blocker of pro-inflammatory cytokines, such as tumour necrosis factor alpha (TNF-α) and interleukin 6 (IL-6). For this reason, the scaffold was built based on natural polymers, including chitosan and type I collagen. The scaffold was grafted next to subchondral bone using hydroxyapatite as filler. One of the biomaterials obtained was also crosslinked to compare its mechanical properties with the non-treated one. Both samples' physicochemical properties were studied with SEM, microCT and photoacoustic imaging, and their rheological properties were also compared. The cell viability and proliferation of the human chondrocyte C28/I2 cell line were studied in vitro. An in vitro and in vivo controlled release study was evaluated in both specimens. The ETA anti-inflammatory effect was also studied by in vitro TNF-α and IL-6 production. The crosslinked and non-treated scaffolds had rheological properties suitable for this application. They were non-cytotoxic and favoured the in vitro growth of chondrocytes. The in vitro and in vivo ETA release showed desirable results for a drug delivery system. The TNF-α and IL-6 production assay showed that this drug was effective as an anti-inflammatory agent. In an in vivo OA mice model, safranin-O and fast green staining was carried out. The OA cartilage tissue improved when the scaffold with ETA was grafted in the damaged area. These results demonstrate that this type of biomaterial has high potential for clinical applications in tissue engineering and as a controlled drug delivery system in OA articular cartilage. ; European Union through the Erasmus PLUS doctoral fellowship (project 2015-1-NL01-KA 107-008639) ; VIDI personal grant (project 723.012.110)