Suchergebnisse

La responsabilidad asignada a la educación para cumplir sus objetivos sociales requiere perfeccionar la preparación de los directores escolares. En la práctica escolar existen debilidades en la dirección del proceso de preparación de estos directivos para el trabajo en red y aporte al desarrollo local. Esta investigación tiene como objetivo proponer una estrategia de preparación de los directores de instituciones educativas de Santa Clara para el trabajo en red que contribuya a elevar la calidad de la educación, en función del desarrollo local. Se emplean métodos empíricos como el análisis de documentos, la observación y la entrevista. En las conclusiones se plantea que la estrategia elaborada se corresponde con el diagnóstico realizado y los especialistas consideran factible su aplicación.

Limbal stem cells (LSCs) are a quiescent cell population responsible for the renewal of the corneal epithelium. Their deficiency is responsible for the conjunctivization of the cornea that is seen in different ocular pathologies, both in humans and in the canine species. The canine species represents an interesting preclinical animal model in ocular surface pathologies. However, the role of LSCs in physiological and pathological conditions in canine species is not well understood. Our objective was to characterize for the first time the soluble factors and the proteomic profile of the secretome and exosomes of canine LSCs (cLSCs). In addition, given the important role that fibroblasts play in the repair of the ocular surface, we evaluated the influence of the secretome and exosomes of cLSCs on their proliferation in vitro. Our results demonstrated a secretory profile of cLSCs with high concentrations of MCP-1, IL-8, VEGF-A, and IL-10, as well as significant production of exosomes. Regarding the proteomic profile, 646 total proteins in the secretome and 356 in exosomes were involved in different biological processes. Functionally, the cLSC secretome showed an inhibitory effect on the proliferation of fibroblasts in vitro, which the exosomes did not. These results open the door to new studies on the possible use of the cLSC secretome or some of its components to treat certain pathologies of the ocular surface in canine species. ; GR was supported by the RD16/0011/ 0022 grant of the Spanish Network on Cell Therapy (TerCel). AV and VF were supported by the Contract Aljama Gestión SL-University of Malaga (8.06/5.02.5013). MM was supported by the UMA18-FEDERJA-133 grant of the Operational programme FEDER Andalucía 2014-2020. CA was supported by the Promotion of Youth Employment and implementation of the Youth Guarantee in R&D&I, 2018 (PEJ2018-004785-A) grant of the Ministry of Science, Innovation and University. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. VI National R&D&I Plan 2008– 2011, Iniciativa Ingenio 2010, Consolider Program, CIBER Actions, Instituto de Salud Carlos III with assistance from the European Regional Development Fund and Regional Government of Andalusia (Junta de Andalucia, PAIDI (BIO217), provided support in the form of materials, but did not have any additional role in the study design, data Cover Letter collection and analysis, decision to publish, or preparation of the manuscript. ; Yes

PurposeThis paper aims to describe an evaluation instrument designed to detect physical barriers and risks in basic activities of daily living (BADLs) performance by senior citizens and presents findings obtained in a representative sample of older persons living in housing programs provided by the State of Chile. Its aim is to develop an objective instrument which can serve as reference point for housing adaptations and improvement or for the use in new designs, appropriate to the changing functional capacities of this age group.Design/methodology/approachThe research is broadly framed in an ecological perspective. It draws on an empirical study, observing older people's BADLs performance in selected State provided housing in the Santiago area. The approach includes some quantitative but mainly qualitative aspects from a descriptive, explanatory and cross sectional perspective. Objective observation of functional BADLs performance, as well as subjective users' perspectives, is compared.FindingsState housing design is significant in BADLs performance, limiting functionality in one third of associated operations observed. These mainly concerned demanding reaching requirements associated with height, but also extended to other inadequacies in design or lack of elements in different situations, which act as barriers or bring potential risks.Research limitations/implicationsHeterogeneity in the functional conditions of older people regardless of age and gender, as well as different housing types makes it difficult to develop standardized recommendations, requiring a tailored approach in the case of adaptations, thus limiting coverage. Further research should be carried out after performing corrective adaptations to evaluate the impact of these interventions.Practical implicationsThe paper prompts a reassessment, by State housing providers, of the architectural design of housing types for older people as well as the adaptation of existing units to extend independence in time rather than undermine it.Social implicationsThe study of the effects of architectural design of housing on older people's independence when performing BADLs is underdeveloped and should be increased in order to promote a better quality of life for this age group through a more friendly and inclusive environment.Originality/valueThis research attempts to generate an objective instrument, useful to provide evidence for architects, designers and policy makers and suitable to be applied in other housing contexts in order to improve the habitat and older people's quality of life.

La evaluación de impacto reviste particular importancia en las organizaciones. Es objetivo de este trabajo proponer un procedimiento para evaluar el impacto de la preparación medioambiental de los directivos en Villa Clara, Cuba, mediante el análisis de un caso de estudio. La metodología empleada parte de una concepción dialéctica materialista, articulando la teoría y práctica sistematizada. Se utilizan como métodos: el análisis de documentos, la entrevista y la encuesta. La muestra estuvo conformada por 15 sujetos. Los resultados revelan las potencialidades y limitaciones que presenta: La evaluación del impacto en preparación medioambiental de directivos, derivándose un procedimiento para perfeccionar este proceso. El estudio culmina con consideraciones finales y recomendaciones que solicitan profundizar en aristas claves del tema poco investigadas.