This book compiles recent research on the modification of nucleic acids. It covers backbone modifications and conjugation of lipids, peptides and proteins to oligonucleotides and their therapeutic use. Synthesis and application in biomedicine and nanotechnology of aptamers, fluorescent and xeno nucleic acids, DNA repair and artificial DNA are discussed as well
Zugriffsoptionen:
Die folgenden Links führen aus den jeweiligen lokalen Bibliotheken zum Volltext:
5480 5482 49 48 ; S ; An aptamer-capped mesoporous material for the selective and sensitive detection of &-thrombin in human plasma and serum has been prepared and characterised. The authors thank the Spanish Government (project MAT2012-38429-C04-01, CTQ2010-20541) the Generalitat Valenciana (project PROMETEO/2009/016) and the CIBER-BBN for their support. C. C. thanks the Universitat Politecnica de Valencia (UPV PAID-06-11) for support. M.O. is grateful to the Universitat Politecnica de Valencia for her grant. Oroval Cucarella, MDM.; Climent Terol, E.; Coll Merino, MC.; Eritja, R.; Aviñó, A.; Marcos Martínez, MD.; Sancenón Galarza, F. (2013). An aptamer-gated silica mesoporous material for thrombin detection. Chemical Communications. 49(48):5480-5482. https://doi.org/10.1039/c3cc42157k Patel, K., Angelos, S., Dichtel, W. R., Coskun, A., Yang, Y.-W., Zink, J. I., & Stoddart, J. F. (2008). Enzyme-Responsive Snap-Top Covered Silica Nanocontainers. Journal of the American Chemical Society, 130(8), 2382-2383. doi:10.1021/ja0772086 Schlossbauer, A., Kecht, J., & Bein, T. (2009). Biotin-Avidin as a Protease-Responsive Cap System for Controlled Guest Release from Colloidal Mesoporous Silica. Angewandte Chemie International Edition, 48(17), 3092-3095. doi:10.1002/anie.200805818 Bernardos, A., Aznar, E., Marcos, M. D., Martínez-Máñez, R., Sancenón, F., Soto, J., … Amorós, P. (2009). Enzyme-Responsive Controlled Release Using Mesoporous Silica Supports Capped with Lactose. Angewandte Chemie International Edition, 48(32), 5884-5887. doi:10.1002/anie.200900880 Park, C., Kim, H., Kim, S., & Kim, C. (2009). Enzyme Responsive Nanocontainers with Cyclodextrin Gatekeepers and Synergistic Effects in Release of Guests. Journal of the American Chemical Society, 131(46), 16614-16615. doi:10.1021/ja9061085 Thornton, P. D., & Heise, A. (2010). Highly Specific Dual Enzyme-Mediated Payload Release from Peptide-Coated Silica Particles. Journal of the American Chemical Society, 132(6), 2024-2028. doi:10.1021/ja9094439 ...
An aptamer-capped mesoporous material for the selective and sensitive detection of &-thrombin in human plasma and serum has been prepared and characterised. ; The authors thank the Spanish Government (project MAT2012-38429-C04-01, CTQ2010-20541) the Generalitat Valenciana (project PROMETEO/2009/016) and the CIBER-BBN for their support. C. C. thanks the Universitat Politecnica de Valencia (UPV PAID-06-11) for support. M.O. is grateful to the Universitat Politecnica de Valencia for her grant. ; Oroval Cucarella, MDM.; Climent Terol, E.; Coll Merino, MC.; Eritja, R.; Aviñó, A.; Marcos Martínez, MD.; Sancenón Galarza, F. (2013). An aptamer-gated silica mesoporous material for thrombin detection. Chemical Communications. 49(48):5480-5482. https://doi.org/10.1039/c3cc42157k ; S ; 5480 ; 5482 ; 49 ; 48 ; Patel, K., Angelos, S., Dichtel, W. R., Coskun, A., Yang, Y.-W., Zink, J. I., & Stoddart, J. F. (2008). Enzyme-Responsive Snap-Top Covered Silica Nanocontainers. Journal of the American Chemical Society, 130(8), 2382-2383. doi:10.1021/ja0772086 ; Schlossbauer, A., Kecht, J., & Bein, T. (2009). Biotin-Avidin as a Protease-Responsive Cap System for Controlled Guest Release from Colloidal Mesoporous Silica. Angewandte Chemie International Edition, 48(17), 3092-3095. doi:10.1002/anie.200805818 ; Bernardos, A., Aznar, E., Marcos, M. D., Martínez-Máñez, R., Sancenón, F., Soto, J., … Amorós, P. (2009). Enzyme-Responsive Controlled Release Using Mesoporous Silica Supports Capped with Lactose. Angewandte Chemie International Edition, 48(32), 5884-5887. doi:10.1002/anie.200900880 ; Park, C., Kim, H., Kim, S., & Kim, C. (2009). Enzyme Responsive Nanocontainers with Cyclodextrin Gatekeepers and Synergistic Effects in Release of Guests. Journal of the American Chemical Society, 131(46), 16614-16615. doi:10.1021/ja9061085 ; Thornton, P. D., & Heise, A. (2010). Highly Specific Dual Enzyme-Mediated Payload Release from Peptide-Coated Silica Particles. Journal of the American Chemical Society, 132(6), 2024-2028. ...