External Quality Assessment for Zika Virus Molecular Diagnostic Testing, Brazil
We conducted an external quality assessment of Zika virus molecular diagnostic tests in Brazil using a new Zika virus standard. Of 15 laboratories, 73% showed limited sensitivity and specificity. Viral load estimates varied significantly. Continuous quality assurance is required for adequate estimates of Zika virus-associated disease and determination of patient care. ; German Centre for Infection Research ; European Union's Horizon research and innovation program (ZIKAlliance) ; EVAg ; Charite, German Ctr Infect Res, Berlin, Germany ; Hosp Univ Prof Edgard Santos, LAPI, Salvador, BA, Brazil ; Fdn Prosangue Hemoctr Sao Paulo, Sao Paulo, Brazil ; Inst Oswaldo Cruz, Rio De Janeiro, Brazil ; Fed Univ Para, Belem, Para, Brazil ; Univ Brasilia, Brasilia, DF, Brazil ; Univ Sao Paulo, Sao Paulo, Brazil ; Fundacao Oswaldo Cruz, Pernambuco, Brazil ; Univ Fed Bahia, Salvador, BA, Brazil ; Diagnost Amer DASA, Sao Paulo, Brazil ; Hosp Israelita Albert Einstein, Sao Paulo, Brazil ; Fac Med Sao Jose do Rio Preto, Sao Jose De Rio Preto, Brazil ; Fdn Med Trop Dr Heitor Vieira Dourado, Manaus, Amazonas, Brazil ; Fundacao Oswaldo Cruz, Salvador, BA, Brazil ; Univ Fed Sao Paulo, Sao Paulo, Brazil ; Aix Marseille Univ, Marseille, France ; Assistance Publ Hop Marseille, Marseille, France ; Univ Bonn, Med Ctr, Bonn, Germany ; Robert Koch Inst, Berlin, Germany ; Univ Fed Sao Paulo, Sao Paulo, Brazil ; ZIKAlliance: 734548 ; EVAg: 653316 ; Web of Science