The aim of the Global Genome Biodiversity Network (GGBN, http://www.ggbn.org) is to foster collaboration among biodiversity biobanks on a global scale in order to further compliance with standards, best practices, and to secure interoperability and exchange of material in accordance with national and international legislation and conventions. Thus, key aspects of GGBN's mission are to develop a network of trusted collections, establishing standards, and identifying best practices by reaching out to other communities. This is especially critical in the light of new international legislation such as the recent Nagoya Protocol on Access and Benefit Sharing (ABS). Biological repositories such as but not limited to natural history collections, botanic gardens, culture collections and zoos are facing a series of challenges triggered by the rapid acceleration in sequencing technology that has put added pressure on the use of samples, which just a few years ago were considered inaccessible for sequencing. ABS legislation applies to nearly all collection types, and with biodiversity biobanks increasing in number worldwide, there is an urgent need to streamline procedures and to ensure legislative compliance. Within Europe it is necessary to 1) reach common standards for biodiversity and environmental biobanks; 2) define best practices for the use of molecular collections; and 3) try to ease exchange of samples and related information, while staying compliant with legislation and conventions. Within the EU funded SYNTHESYS+ project (http://www.synthesys.info), GGBN is leading Network Activity 3 (NA3). An overview of planned activities and tasks will be given here with special emphasis on linkages within and beyond SYNTHESYS+.
The aim of the Global Genome Biodiversity Network (GGBN, http://www.ggbn.org) is to foster collaboration among biodiversity biobanks on a global scale in order to further compliance with standards, best practices, and to secure interoperability and exchange of material in accordance with national and international legislation and conventions. Thus, key aspects of GGBN's mission are to develop a network of trusted collections, establishing standards, and identifying best practices by reaching out to other communities. This is especially critical in the light of new international legislation such as the recent Nagoya Protocol on Access and Benefit Sharing (ABS). Biological repositories such as but not limited to natural history collections, botanic gardens, culture collections and zoos are facing a series of challenges triggered by the rapid acceleration in sequencing technology that has put added pressure on the use of samples, which just a few years ago were considered inaccessible for sequencing. ABS legislation applies to nearly all collection types, and with biodiversity biobanks increasing in number worldwide, there is an urgent need to streamline procedures and to ensure legislative compliance. Within Europe it is necessary to 1) reach common standards for biodiversity and environmental biobanks; 2) define best practices for the use of molecular collections; and 3) try to ease exchange of samples and related information, while staying compliant with legislation and conventions. Within the EU funded SYNTHESYS+ project (http://www.synthesys.info), GGBN is leading Network Activity 3 (NA3). An overview of planned activities and tasks will be given here with special emphasis on linkages within and beyond SYNTHESYS+.
Transparency as well as complete and traceable documentation of specimens, samples and associated information are prerequisites to comply with laws and regulations in Provider and User Countries to ensure benefits of utilised genetic resources are shared. Besides legal compliance, these measures should also help to build trust among users, suppliers and collaborators. This concerns for example laws of providing countries that have established access laws under the Nagoya Protocol, such as Mexico's Ley General de la Vida Silvestre, or under the Convention of Biological Diversity (CBD), such as the Brazil Law No. 13,123, regulating access to the country's genetic heritage. On the other hand there are laws and regulations in user countries that ensure compliance with access laws of providing countries under the Nagoya protocol (e. g. Regulation (EU) No 511/2014 of the European Parliament and of the Council of 16. April 2014, which has to be implemented at national level in the EU member states). As an institution holding genetic resources as living collections (including seeds), herbarium specimens and DNA and tissue samples as well as a wealth of associated data, the Botanic Garden and Botanical Museum Berlin (BGBM) aims at creating transparency on the processes associated with the handling of these materials and data, such as metadata or associated analytical research results (Fig. 1). As a member of CETAF (Consortium of European Taxonomic Facilities), IPEN (International Plant Exchange Network), and GGBN (Global Genome Biodiversity Network) the workflows and documentation of biological collections at BGBM are in compliance with CETAF's Code of Conduct on Access and Benefit Sharing (https://www.cetaf.org/services/natural-science-collections-and-access-and-benefit-sharing) for herbarium specimens including algae, IPEN´s Code of Conduct (http://www.bgci.org/policy/ipen) for living plants and seeds, and GGBN's (https://library.ggbn.org/share/s/UM5JietQR9aevtYDymHbjw) code of conduct (CoC) for DNA and tissue samples. A major challenge was to ensure the comprehensive, transparent, and traceable documentation of specimens and associated material and information along our internal workflows that have evolved with the development of a manifold of protocols. However, this challenge presented the opportunity to revise the existing protocols that cover the handling, collecting, and processing of the specimens, which had accumulated over the long history of our collections and our databases, into a consistent set of workflows (Stevens et al. 2019). A key component is the Collection Data Form (CDF) which guarantees that all necessary documentation will be imported into our collection management systems, including potential restriction of destructive sampling or loaning. The latest version of the CDF as wells as other information about BGBM's collection and data workflows can be found at https://wiki.bgbm.org/collectionworkflows. This site has been created in late 2018 to be used by everyone to explore BGBM's routines and examples. All legal and formal documents, such as collecting permits, Prior Informed Consent (PIC), CITES documentation, phytosanitary documents, Material Transfer Agreement (MTA), long term agreements with partner institutions, project agreements etc., are digitized and managed using a digital asset management software (Alfresco, an open source document management system, www.alfresco.com. The challenge is to link all this information unambiguously. To achieve this, all of BGBM's collections (tissue and DNA-samples as well as living plants, seeds and diatom cultures) must have, whenever possible, a herbarium specimen that can be permanently stored and that allows a correct taxonomic identification of the material. These voucher specimens shall be digitized. Therefore, all data and all documentation can be traced back to identifiers referring to a herbarium specimen or living accession. The other collections (e. g. DNA and tissue samples) also get unique identifiers that are cross-referenced with each other. By this process we ensure that genetic material is identified by collecting number (assigned by the collector), as well as accession number and barcodes (assigned by BGBM according to type of material such as plant tissue, DNA, sample, seed lot, plant accession number of living plants, environmental sample, culture strain or herbarium specimen), and, most importantly in this regard, the document number/identifier of the legal or formal documents issued by the national legal entity or signed by a partner institution (assigned by the documentation office at BGBM when digitized). All these identifiers or numbers must refer to the respective material and as such allow BGBM to trace back the material at all stages of processing. This is of vital importance when genetic material is exchanged with partners. If there are any restrictions or any requirements for the further processing, use or exchange of plant material this is documented and flagged in all database modules and accession numbers.
Transparency as well as complete and traceable documentation of specimens, samples and associated information are prerequisites to comply with laws and regulations in Provider and User Countries to ensure benefits of utilised genetic resources are shared. Besides legal compliance, these measures should also help to build trust among users, suppliers and collaborators. This concerns for example laws of providing countries that have established access laws under the Nagoya Protocol, such as Mexico's Ley General de la Vida Silvestre, or under the Convention of Biological Diversity (CBD), such as the Brazil Law No. 13,123, regulating access to the country's genetic heritage. On the other hand there are laws and regulations in user countries that ensure compliance with access laws of providing countries under the Nagoya protocol (e. g. Regulation (EU) No 511/2014 of the European Parliament and of the Council of 16. April 2014, which has to be implemented at national level in the EU member states). As an institution holding genetic resources as living collections (including seeds), herbarium specimens and DNA and tissue samples as well as a wealth of associated data, the Botanic Garden and Botanical Museum Berlin (BGBM) aims at creating transparency on the processes associated with the handling of these materials and data, such as metadata or associated analytical research results (Fig. 1). As a member of CETAF (Consortium of European Taxonomic Facilities), IPEN (International Plant Exchange Network), and GGBN (Global Genome Biodiversity Network) the workflows and documentation of biological collections at BGBM are in compliance with CETAF's Code of Conduct on Access and Benefit Sharing (https://www.cetaf.org/services/natural-science-collections-and-access-and-benefit-sharing) for herbarium specimens including algae, IPEN´s Code of Conduct (http://www.bgci.org/policy/ipen) for living plants and seeds, and GGBN's (https://library.ggbn.org/share/s/UM5JietQR9aevtYDymHbjw) code of conduct (CoC) for DNA and tissue samples. ...
Many institutions harbor living collections in the form of living plants, animals, microrganisms or seeds. In the framework of the TDWG collections and specimen descriptions standards, it has become important to align exisiting standards for living collections and specimens or to identify where concepts or controlled vocabularies would be needed in the current TDWG standards. In September 2021 a workshop was organized in the framework of the COST Action Mobilise (https://www.mobilise-action.eu/) to get a better common understanding of the different types of living collections to consider and set the scene for further work on standards alignments. The EU COST Action CA17106 on "Mobilising Data, Experts and Policies in Scientific Collections". Invited experts to these workshop were representatives of the TDWG Collection Description Group, the GGBN and TDWG molecular collections group, living plants collections and seed banks (Botanic Gardens Conservation International: BGCI, https://www.bgci.org/), living animal and biobanks (European Association of Zoos and Aquaria: EAZA, https://www.eaza.net/) and the culture collections (World Federation for Culture Collections: WFCC, http://www.wfcc.info/), who gave presentations on their currently used standards and challenges.The second day was devoted to break out sessions to brainstorm the specific needs for the different living collections with the aim to check and update the controlled vocabularies and concepts as needed.Identified topics were : Session 1: Voucher specimens of living accessions.Session 2: Living collections and GBIF.Session 3: How do we compare botanical gardens with herbaria?Session 4: How do we compare zoos and aquaria with natural history collections?Session 5: Culture collections: best practices and guidelines.The goal of this presentation is to address the outcome of these sessions and recommend future steps in collaboration with TDWG and the different identified stakeholders.
Many institutions harbor living collections in the form of living plants, animals, microrganisms or seeds. In the framework of the TDWG collections and specimen descriptions standards, it has become important to align exisiting standards for living collections and specimens or to identify where concepts or controlled vocabularies would be needed in the current TDWG standards. In September 2021 a workshop was organized in the framework of the COST Action Mobilise (https://www.mobilise-action.eu/) to get a better common understanding of the different types of living collections to consider and set the scene for further work on standards alignments. The EU COST Action CA17106 on "Mobilising Data, Experts and Policies in Scientific Collections". Invited experts to these workshop were representatives of the TDWG Collection Description Group, the GGBN and TDWG molecular collections group, living plants collections and seed banks (Botanic Gardens Conservation International: BGCI, https://www.bgci.org/), living animal and biobanks (European Association of Zoos and Aquaria: EAZA, https://www.eaza.net/) and the culture collections (World Federation for Culture Collections: WFCC, http://www.wfcc.info/), who gave presentations on their currently used standards and challenges.The second day was devoted to break out sessions to brainstorm the specific needs for the different living collections with the aim to check and update the controlled vocabularies and concepts as needed.Identified topics were : Session 1: Voucher specimens of living accessions.Session 2: Living collections and GBIF.Session 3: How do we compare botanical gardens with herbaria?Session 4: How do we compare zoos and aquaria with natural history collections?Session 5: Culture collections: best practices and guidelines.The goal of this presentation is to address the outcome of these sessions and recommend future steps in collaboration with TDWG and the different identified stakeholders.
