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The emergence of specialized markets has profoundly improved the means of market access, enriched the driving forces of value chains, and changed the business environment for small firms in the developing world. This ground-breaking book summarizes the experience of specialized markets in a systematic manner. Specialized markets are a unique product of China's economic transition. They are marketplaces located in industrial clusters, specializing in the wholesale of local commodities and related goods. Ding Ke reveals that despite their seemingly primitive form, specialized markets appeared in

Food, energy, and water (FEW) are primary resources required for human populations and ecosystems. Availability of the raw resources is essential, but equally important are the services that deliver resources to human populations, such as adequate access to safe drinking water, electricity, and sufficient food. Any failures in either resource availability or FEW resources-related services will have an impact on human health. The ability of countries to intervene and overcome the challenges in the FEW domain depends on governance, education, and economic capacities. We distinguish between FEW resources, FEW services, and FEW health outcomes to develop an analysis framework for evaluating interrelationships among these critical resources. The framework is applied using a data-driven approach for sub-Saharan African countries, a region with notable FEW insecurity challenges. The data-driven approach using a cross-validated stepwise regression analysis indicates that limited governance and socioeconomic capacity in sub-Saharan African countries, rather than lack of the primary resources, more significantly impact access to FEW services and associated health outcomes. The proposed framework helps develop a cohesive approach for evaluating FEW metrics and could be applied to other regions of the world to continue improving our understanding of the FEW nexus. ; This work was supported in part by funding from NSF-EAR 1416964. Sandia National Laboratories is a multimission laboratory managed and operated by the National Technology and Engineering Solutions of Sandia, LLC, a wholly owned subsidiary of Honeywell International, Inc., for the U.S. Department of Energy's National Nuclear Security Administration under contract DE-NA0003525. The views expressed in the article do not necessarily represent the views of the U.S. Department of Energy or the U.S. Government. All the data are from databases published online as cited in Tables S1 and S2. The compiled data set and code used in the CVSRA are available in the following GitHub repository (https://github.com/ding-k/Earth-s-Future-Supporting-Information-Code-and-Data.git).

AbstractThis study presents a state‐level systematic review of geospatial representation of Community Water Systems (CWSs) in the United States. We conducted online searches and contacted government, water industry, and academic representatives to obtain these data. CWS geospatial data were characterized by vector type, methodological approaches, data sources, availability to the public, entities involved in creation and maintenance of data, and CWS map requirements by primacy agency. We found that 24 states and the District of Columbia had geospatial representation of CWS estimated service area boundary (ESAB) (i.e., polygons), which were harmonized to construct a geospatial database representative of available CWS ESABs. Our findings aim to prompt discussion among myriad stakeholders on the need to create, standardize, and maintain CWS ESABs to ensure water justice for all communities.

BACKGROUND: The severities of human adenovirus (HAdV) infection are diverse in different areas of Tibet, China, where a large altitude span emerges. Serious consequences may be caused by medical staff if the clinical stages and immunological conditions of patients in high-altitude areas are misjudged. However, the clinical symptoms, immunological characteristics, and environmental factors of HAdV infection patients at different altitude areas have not been well described. METHODS: In this retrospective, multicenter cohort study, we analyzed the data of patients who were confirmed HAdV infection by PCR tests in the General Hospital of Tibet Military Command or CDC (the Center for Disease Control and Prevention) of Tibet Military Command from January 1, 2019, to December 31, 2020. Demographic, clinical, laboratory, radiological, and epidemiological data were collected from medical records system and compared among different altitude areas. The inflammatory cytokines as well as the subsets of monocytes and regulatory T cells of patients were also obtained and analyzed in this study. RESULTS: Six hundred eighty-six patients had been identified by laboratory-confirmed HAdV infection, including the low-altitude group (n = 62), medium-altitude group (n = 206), high-altitude group (n = 230), and ultra-high-altitude group (n = 188). Referring to the environmental factors regression analysis, altitude and relative humidity were tightly associated with the number of infected patients (P < 0.01). A higher incidence rate of general pneumonia (45.7%) or severe pneumonia (8.0%) occurred in the ultra-high-altitude group (P < 0.05). The incubation period, serial interval, course of the disease, and PCR-positive duration were prolonged to various extents compared with the low-altitude group (P < 0.05). Different from those in low-altitude areas, the levels of IL-1β, IL-2, IL-4, IL-6, IL-8, IL-10, G-CSF, GM-CSF, IFN-γ, IP-10, MCP-1, TNF-α, TNF-β, and VEGF in the plasma of the ultra-high-altitude group were increased (P ...