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Open Access#12020

Trodusquemine displaces protein misfolded oligomers from cell membranes and abrogates their cytotoxicity through a generic mechanism

10 pags., 5 figs. ; The onset and progression of numerous protein misfolding diseases are associated with the presence of oligomers formed during the aberrant aggregation of several different proteins, including amyloid-β (Aβ) in Alzheimer's disease and α-synuclein (αS) in Parkinson's disease. These small, soluble aggregates are currently major targets for drug discovery. In this study, we show that trodusquemine, a naturally-occurring aminosterol, markedly reduces the cytotoxicity of αS, Aβ and HypF-N oligomers to human neuroblastoma cells by displacing the oligomers from cell membranes in the absence of any substantial morphological and structural changes to the oligomers. These results indicate that the reduced toxicity results from a mechanism that is common to oligomers from different proteins, shed light on the origin of the toxicity of the most deleterious species associated with protein aggregation and suggest that aminosterols have the therapeutically-relevant potential to protect cells from the oligomer-induced cytotoxicity associated with numerous protein misfolding diseases. ; This work was supported by the Cambridge Centre for Misfolding Diseases (R.L., B.M., F.S.R., C.K.X., M.P., S.C., S.W.C., J.H., T.K., J.R.K., T.P.J.K., M.V., and C.M.D.), the UK Biotechnology and Biochemical Sciences Research Council (M.V. and C.M.D.), the Wellcome Trust (203249/Z/16/Z to T.P.J.K and M.V.), the Frances and Augustus Newman Foundation (T.P.J.K.), the Regione Toscana – FAS Salute, project SUPREMAL (R.C., A.B., C.C., and F.C.), the Gates Cambridge Trust and St. John's College Cambridge (R.L.), Darwin College Cambridge (F.S.R.), the Herchel Smith Fund (C.K.X.), a Faculty Development Research Fund grant from the United States Military Academy, West Point (R.L.) and a DTRA Service Academy Research Initiative grant (HDTRA1033862 to R.L.).

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Open Access

Open Access#22018

Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine

12 pags, 3 figs. -- The Supporting Information is available free of charge on the ACS Publications website at DOI:10.1021/acschembio.8b00466. ; The aggregation of α-synuclein, an intrinsically disordered protein that is highly abundant in neurons, is closely associated with the onset and progression of Parkinson's disease. We have shown previously that the aminosterol squalamine can inhibit the lipid induced initiation process in the aggregation of α-synuclein, and we report here that the related compound trodusquemine is capable of inhibiting not only this process but also the fibril-dependent secondary pathways in the aggregation reaction. We further demonstrate that trodusquemine can effectively suppress the toxicity of α-synuclein oligomers in neuronal cells, and that its administration, even after the initial growth phase, leads to a dramatic reduction in the number of α-synuclein inclusions in a Caenorhabditis elegans model of Parkinson's disease, eliminates the related muscle paralysis, and increases lifespan. On the basis of these findings, we show that trodusquemine is able to inhibit multiple events in the aggregation process of α-synuclein and hence to provide important information about the link between such events and neurodegeneration, as it is initiated and progresses. Particularly in the light of the previously reported ability of trodusquemine to cross the blood-brain barrier and to promote tissue regeneration, the present results suggest that this compound has the potential to be an important therapeutic candidate for Parkinson's disease and related disorders. ; This work was supported by the Boehringer Ingelheim Fonds (P.F.), the Studienstiftung des Deutschen Volkes (P.F.), Gates Cambridge Scholarships (R.L. and G.T.H) and a St. John's College Benefactors' Scholarship (R.L.), the UK Biotechnology and Biochemical Sciences Research Council (M.V. and C.M.D.), a Senior Research Fellowship award from the Alzheimer's Society, UK, grant number (317, AS-SF-16-003) (F.A.A.), the Wellcome Trust (C.M.D., M.V., and T.P.J.K.), the Frances and Augustus Newman Foundation (T.P.J.K.), the Regione Toscana—FAS Salute—Supremal project (R.C., C.C., and F.C.), a Marie Skłodowska-Curie Actions—Individual Fellowship (C.G.), Sidney Sussex College Cambridge (G.M.), the Spanish Government—MINECO (N.C.), and by the Cambridge Centre for Misfolding Diseases (M.P., P.F., R.L., F.A.A., C.G., G.T.H., S.W.C., J.R.K., T.P.J.K., M.V., and C.M.D).

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Open Access

Open Access#32019

An embedding technique to determine tau tau backgrounds in proton-proton collision data

Sirunyan, A. M; Tumasyan, A; Adam, W; Ambrogi, F; Asilar, E; Bergauer, T; Brandstetter, J; Dragicevic, M

Sirunyan, A. M; Tumasyan, A; Adam, W; Ambrogi, F; Asilar, E; Bergauer, T; Brandstetter, J; Dragicevic, M; Eroe, J; Del Valle, A. Escalante; Flechl, M; Fruehwirth, R; Ghete, V. M; Hrubec, J; Jeitler, M; Krammer, N; Kraetschmer, I; Liko, D; Madlener, T; Mikulec, I; Rad, N; Rohringer, H; Schieck, J; Schoefbeck, R; Spanring, M; Spitzbart, D; Taurok, A; Waltenberger, W; Wittmann, J; Wulz, C-E; Zarucki, M; Chekhovsky, V; Mossolov, V; Gonzalez, J. Suarez; De Wolf, E. A; Di Croce, D; Janssen, X; Lauwers, J; Pieters, M; Van Haevermaet, H; Van Mechelen, P; Van Remortel, N; Blekman, F; D'Hondt, J; De Clercq, J; Deroover, K; Flouris, G; Lontkovskyi, D; Lowette, S; Marchesini, I; Moortgat, S; Moreels, L; Python, Q; Skovpen, K; Tavernier, S; Van Doninck, W; Van Mulders, P; Van Parijs, I; Beghin, D; Bilin, B; Brun, H; Clerbaux, B; De Lentdecker, G; Delannoy, H; Dorney, B; Fasanella, G; Favart, L; Goldouzian, R; Grebenyuk, A; Kalsi, A. K; Luetic, J; Popov, A; Postiau, N; Starling, E; Thomas, L; Vander Velde, C; Vanlaer, P; Vannerom, D; Wang, Q; Cornelis, T; Dobur, D; Fagot, A; Gul, M; Khvastunov, I; Roskas, C; Trocino, D; Tytgat, M; Verbeke, W; Vermassen, B; Vit, M; Zaganidis, N; Bakhshiansohi, H; Bondu, O; Bruno, G; Caputo, C; David, P; Delaere, C; Delcourt, M; Giammanco, A; Krintiras, G; Lemaitre, V; Magitteri, A; Piotrzkowski, K; Saggio, A; Marono, M. Vidal; Vischi, P; Zobec, J; Alves, F. L; Alves, G. A; Correia Silva, G; Hensel, C; Moraes, A; Pol, M. E; Rebello Teles, P; Belchior Batista Das Chagas, E; Carvalho, W; Chinellato, J; Coelho, E; Da Costa, E. M; Da Silveira, G. G; De Jesus Damiao, D; De Oliveira Martins, C; Fonseca De Souza, S; Malbouisson, H; Matos Figueiredo, D; Melo De Almeida, M; Mora Herrera, C; Mundim, L; Nogima, H; Prado Da Silva, W. L; Sanchez Rosas, L. J; Santoro, A; Sznajder, A; Thiel, M; Tonelli Manganote, E. J; Torres Da Silva De Araujo, F; Vilela Pereira, A; Ahuja, S; Bernardes, C. A; Calligaris, L; Fernandez Perez Tomei, T. R; Gregores, E. M; Mercadante, P. G; Novaes, S. F; Padula, Sandra S; Aleksandrov, A; Hadjiiska, R; Iaydjiev, P; Marinov, A; Misheva, M; Rodozov, M; Shopova, M; Sultanov, G; Dimitrov, A; Litov, L; Pavlov, B; Petkov, P; Fang, W; Gao, X; Yuan, L; Ahmad, M; Bian, J. G; Chen, G. M; Chen, H. S; Chen, M; Chen, Y; Jiang, C. H; Leggat, D; Liao, H; Liu, Z; Shaheen, S. M; Spiezia, A; Tao, J; Yazgan, E; Zhang, H; Zhang, S; Zhao, J; Ban, Y; Chen, G; Levin, A; Li, J; Li, L; Li, Q; Mao, Y; Qian, S. J; Wang, D; Wang, Y; Avila, C; Cabrera, A; Carrillo Montoya, C. A; Chaparro Sierra, L. F; Florez, C; Gonzalez Hernandez, C. F; Segura Delgado, M. A; Godinovic, N; Lelas, D; Puljak, I; Sculac, T; Antunovic, Z; Kovac, M; Brigljevic, V; Ferencek, D; Kadija, K; Mesic, B; Starodumov, A; Susa, T; Ather, M. W; Attikis, A; Kolosova, M; Mavromanolakis, G; Mousa, J; Nicolaou, C; Ptochos, F; Razis, P. A; Rykaczewski, H; Finger, M; Finger Jr, M. Jr; Ayala, E; Carrera Jarrin, E; Ellithi Kamel, A; Mahmoud, M. A; Salama, E; Bhowmik, S; De Oliveira, A. Carvalho Antunes; Dewanjee, R. K; Ehataht, K; Kadastik, M; Raidal, M; Veelken, C; Eerola, P; Kirschenmann, H; Pekkanen, J; Voutilainen, M; Havukainen, J; Heikkila, J. K; Jarvinen, T; Karimaki, V; Kinnunen, R; Lampen, T; Lassila-Perini, K; Laurila, S; Lehti, S; Linden, T; Luukka, P; Maenpaa, T; Siikonen, H; Tuominen, E; Tuominiemi, J; Tuuva, T; Besancon, M; Couderc, F; Dejardin, M; Denegri, D; Faure, J. L; Ferri, F; Ganjour, S; Givernaud, A; Gras, P; Monchenault, G. Hamel de; Jarry, P; Leloup, C; Locci, E; Malcles, J; Negro, G; Rander, J; Rosowsky, A; Sahin, M. O; Titov, M; Abdulsalam, A; Amendola, C; Antropov, I; Beaudette, F; Busson, P; Charlot, C; Diab, B; Cassagnac, R. Granier de; Kucher, I; Lobanov, A; Blanco, J. Martin; Nguyen, M; Ochando, C; Ortona, G; Paganini, P; Pigard, P; Salerno, R; Sauvan, J. B; Sirois, Y; Leiton, A. G. 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P; Schomakers, C; Schulz, J; Teroerde, M; Wittmer, B; Albert, A; Erdmann, M; Erdweg, S; Fischer, R; Fischer, S; Guth, A; Hebbeker, T; Heidemann, C; Hoepfner, K; Keller, H; Mastrolorenzo, L; Merschmeyer, M; Meyer, A; Millet, P; Mukherjee, S; Pook, T; Radziej, M; Reithler, H; Rieger, M; Scheuch, F; Schmidt, A; Teyssier, D; Thueer, S; Fluegge, G; Hlushchenko, O; Kress, T; Mueller, T; Nehrkorn, A; Nowack, A; Pistone, C; Pooth, O; Roy, D; Sert, H; Stahl, A; Martin, M. Aldaya; Arndt, T; Asawatangtrakuldee, C; Babounikau, I; Beernaert, K; Behnke, O; Behrens, U; Martinez, A. Bermudez; Bertsche, D; Bin Anuar, A. A; Borras, K; Botta, V; Campbell, A; Connor, P; Contreras-Campana, C; Danilov, V; De Wit, A; Defranchis, M. M; Pardos, C. Diez; Damiani, D. Dominguez; Eckerlin, G; Eichhorn, T; Elwood, A; Eren, E; Gallo, E; Geiser, A; Luyando, J. M. Grados; Grohsjean, A; Guthoff, M; Haranko, M; Harb, A; Jung, H; Kasemann, M; Keaveney, J; Kleinwort, C; Knolle, J; Kruecker, D; Lange, W; Lenz, T; Lipka, K; Lohmann, W; Mankel, R; Melzer-Pellmann, I-A; Meyer, A. B; Meyer, M; Missiroli, M; Mittag, G; Mnich, J; Myronenko, V; Pflitsch, S. K; Pitzl, D; Raspereza, A; Savitskyi, M; Saxena, P; Schuetze, P; Schwanenberger, C; Shevchenko, R; Singh, A; Tholen, H; Turkot, O; Vagnerini, A; Van Onsem, G. P; Walsh, R; Wen, Y; Wichmann, K; Wissing, C; Zenaiev, O; Aggleton, R; Bein, S; Benato, L; Benecke, A; Blobel, V; Dreyer, T; Ebrahimi, A; Garutti, E; Gonzalez, D; Haller, J; Hinzmann, A; Karavdina, A; Kasieczka, G; Klanner, R; Kogler, R; Kovalchuk, N; Kurz, S; Kutzner, V; Lange, J; Marconi, D; Multhaup, J; Niedziela, M; Niemeyer, C. E. N; Nowatschin, D; Perieanu, A; Reimers, A; Rieger, O; Scharf, C; Schleper, P; Schumann, S; Schwandt, J; Sonneveld, J; Stadie, H; Steinbrueck, G; Stober, F. M; Stoever, M; Vormwald, B; Zoi, I; Akbiyik, M; Barth, C; Baselga, M; Baur, S; Bechtel, J; Brommer, S; Butz, E; Caspart, R; Chwalek, T; Colombo, F; De Boer, W; Dierlamm, A; El Morabit, K; Faltermann, N; Freund, B; Giffels, M; Gottmann, A; Harrendorf, M. A; Hartmann, F; Heindl, S. M; Husemann, U; Katkov, I; Kudella, S; Mitra, S; Mozer, M. U; Mueller, Th; Plagge, M; Quast, G; Rabbertz, K; Schroeder, M; Shvetsov, I; Simonis, H. J; Ulrich, R; Wayand, S; Weber, M; Weiler, T; Williamson, S; Woehrmann, C; Wolf, R; Anagnostou, G; Daskalakis, G; Geralis, T; Kyriakis, A; Loukas, D; Paspalaki, G; Karathanasis, G; Kesisoglou, S; Kontaxakis, P; Panagiotou, A; Papavergou, I; Saoulidou, N; Vellidis, K; Kousouris, K; Papakrivopoulos, I; Tsipolitis, G; Evangelou, I; Foudas, C; Gianneios, P; Katsoulis, P; Kokkas, P; Mallios, S; Manthos, N; Papadopoulos, I; Paradas, E; Strologas, J; Triantis, F. A; Tsitsonis, D; Bartok, M; Csanad, M; Filipovic, N; Major, P; Nagy, M; Pasztor, G; Suranyi, O; Veres, G; Bencze, G; Hajdu, C; Horvath, D; Hunyadi, A; Sikler, F; Vami, T. A; Veszpremi, V; Vesztergombi, G; Beni, N; Czellar, S; Karancsi, J; Makovec, A; Molnar, J; Szillasi, Z; Raics, P; Trocsanyi, Z. L; Ujvari, B; Choudhury, S; Komaragiri, J. R; Tiwari, P. C; Bahinipati, S; Kar, C; Mal, P; Nayak, A; Chowdhury, S. Roy; Sahoo, D. K; Swain, S. K; Bansal, S; Beni, S. B; Bhatnagar, V; Chauhan, S; Chawla, R; Dhingra, N; Gupta, R; Kaur, A; Kaur, M; Kaur, S; Kumar, R; Kumari, P; Lohan, M; Mehta, A; Sandeep, K; Sharma, S; Singh, J. B; Walia, G; Bhardwaj, A; Choudhary, B. C; Garg, R. B; Gola, M; Keshri, S; Kumar, Ashok; Malhotra, S; Naimuddin, M; Priyanka, P; Ranjan, K; Shah, Aashaq; Sharma, R; Bhardwaj, R; Bharti, M; Bhattacharya, R; Bhattacharya, S; Bhawandeep, U; Bhowmik, D; Dey, S; Dutt, S; Dutta, S; Mondal, K; Nandan, S; Purohit, A; Rout, P. K; Roy, A; Saha, G; Sarkar, S; Sharan, M; Singh, B; Thakur, S; Behera, P. K; Muhammad, A; Woods, N; Chudasama, R; Dutta, D; Jha, V; Kumar, V; Netrakanti, P. K; Pant, L. M; Shukla, P; Suggisetti, P; Aziz, T; Bhat, M. A; Dugad, S; Mohanty, G. B; Sur, N; Verma, RavindraKumar; Banerjee, S; Chatterjee, S; Das, P; Guchait, M; Jain, Sa; Karmakar, S; Kumar, S; Majumder, G; Mazumdar, K; Sahoo, N; Dube, S; Hegde, V; Kapoor, A; Kothekar, K; Pandey, S; Rane, A; Rastogi, A; Chenarani, S; Tadavani, E. Eskandari; Etesami, S. M; Khakzad, M; Najafabadi, M. Mohammadi; Naseri, M; Hosseinabadi, F. Rezaei; Safarzadeh, B; Zeinali, M; Felcini, M; Grunewald, M; Abbrescia, M; Calabria, C; Colaleo, A; Creanza, D; Cristella, L; De Filippis, N; De Palma, M; Di Florio, A; Errico, F; Fiore, L; Gelmi, A; Iaselli, G; Ince, M; Lezki, S; Maggi, G; Maggi, M; Miniello, G; My, S; Nuzzo, S; Pompili, A; Pugliese, G; Radogna, R; Ranieri, A; Selvaggi, G; Sharma, A; Silvestris, L; Venditti, R; Verwilligen, P; Abbiendi, G; Battilana, C; Bonacorsi, D; Borgonovi, L; Braibant-Giacomelli, S; Campanini, R; Capiluppi, P; Castro, A; Cavallo, F. R; Chhibra, S. S; Ciocca, C; Codispoti, G; Cuffiani, M; Dallavalle, G. M; Fabbri, F; Fanfani, A; Giacomelli, P; Grandi, C; Guiducci, L; Iemmi, F; Marcellini, S; Masetti, G; Montanari, A; Navarria, F. L; Perrotta, A; Primavera, F; Rossi, A. M; Rovelli, T; Siroli, G. P; Tosi, N; Albergo, S; Di Mattia, A; Potenza, R; Tricomi, A; Tuve, C; Barbagli, G; Chatterjee, K; Ciulli, V; Civinini, C; D'Alessandro, R; Focardi, E; Latino, G; Lenzi, P; Meschini, M; Paoletti, S; Russo, L; Sguazzoni, G; Strom, D; Viliani, L; Benussi, L; Bianco, S; Piccolo, D; Ferro, F; Mulargia, R; Robutti, E; Tosi, S; Benaglia, A; Beschi, A; Brivio, F; Ciriolo, V; Di Guida, S; Dinardo, M. E; Fiorendi, S; Gennai, S; Ghezzi, A; Govoni, R; Malberti, M; Malvezzi, S; Massironi, A; Menasce, D; Moroni, L; Paganoni, M; Pedrini, D; Ragazzi, S; Fatis, T. Tabarelli de; Zuolo, D; Buontempo, S; Cavallo, N; Di Crescenzo, A; Fabozzi, F; Fienga, F; Galati, G; Iorio, A. O. M; Lista, L; Meola, S; Paolucci, P; Sciacca, C; Voevodina, E; Azzi, P; Bacchetta, N; Bisello, D; Boletti, A; Bragagnolo, A; Carlin, R; Checchia, P; Dall'Osso, M; Manzano, P. De Castro; Dorigo, T; Dosselli, U; Gasparini, F; Gasparini, U; Gozzelino, A; Hoh, S. Y; Lacaprara, S; Lujan, P; Margoni, M; Meneguzzo, A. T; Pazzini, J; Ronchese, P; Rossin, R; Simonetto, F; Tiko, A; Torassa, E; Zanetti, M; Zotto, P; Zumerle, G; Braghieri, A; Magnani, A; Montagna, P; Ratti, S. P; Re, V; Ressegotti, M; Riccardi, C; Salvini, P; Vai, I; Vitulo, P; Biasini, M; Bilei, G. M; Cecchi, C; Ciangottini, D; Fano, L; Lariccia, P; Leonardi, R; Manoni, E; Mantovani, G; Mariani, V; Menichelli, M; Rossi, A; Santocchia, A; Spiga, D; Androsov, K; Azzurri, P; Bagliesi, G; Bianchini, L; Boccali, T; Borrello, L; Castaldi, R; Ciocci, M. A; Dell'Orso, R; Fedi, G; Fiori, F; Giannini, L; Giassi, A; Grippo, M. T; Ligabue, F; Manca, E; Mandorli, G; Messineo, A; Palla, F; Rizzi, A; Spagnolo, P; Tenchini, R; Tonelli, G; Venturi, A; Verdini, P. 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Austrian Federal Ministry of Education, Science and Research ; Austrian Science Fund ; Belgian Fonds de la Recherche Scientifique ; Fonds voor Wetenschappelijk Onderzoek ; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) ; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) ; Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ) ; FAPERGS ; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) ; Bulgarian Ministry of Education and Science ; CERN ; Chinese Academy of Sciences ; Ministry of Science and Technology ; National Natural Science Foundation of China ; Colombian Funding Agency (COLCIENCIAS) ; Croatian Ministry of Science, Education and Sport ; Croatian Science Foundation ; Research Promotion Foundation, Cyprus ; Secretariat for Higher Education, Science, Technology and Innovation, Ecuador ; Ministry of Education and Research, Estonia ; Estonian Research Council, Estonia ; European Regional Development Fund, Estonia ; Academy of Finland ; Finnish Ministry of Education and Culture ; Helsinki Institute of Physics ; Institut National de Physique Nucleaire et de Physique des Particules / CNRS, France ; Commissariat a l'Energie Atomique et aux Energies Alternatives / CEA, France ; Bundesministerium fur Bildung und Forschung, Germany ; Deutsche Forschungsgemeinschaft, Germany ; Helmholtz-Gemeinschaft Deutscher Forschungszentren, Germany ; General Secretariat for Research and Technology, Greece ; National Research, Development and Innovation Fund, Hungary ; Department of Atomic Energy, India ; Department of Science and Technology, India ; Institute for Studies in Theoretical Physics and Mathematics, Iran ; Science Foundation, Ireland ; Istituto Nazionale di Fisica Nucleare, Italy ; Ministry of Science, ICT and Future Planning, Republic of Korea ; National Research Foundation (NRF), Republic of Korea ; Ministry of Education and Science of the Republic of Latvia ; Lithuanian Academy of Sciences ; Ministry of Education ; University of Malaya (Malaysia) ; Ministry of Science of Montenegro ; BUAP ; CINVESTAV ; CONACYT ; LNS ; SEP ; UASLP-FAI ; Ministry of Business, Innovation and Employment, New Zealand ; Pakistan Atomic Energy Commission ; Ministry of Science and Higher Education, Poland ; National Science Center, Poland ; Fundacao para a Ciencia e a Tecnologia, Portugal ; JINR, Dubna ; Ministry of Education and Science of the Russian Federation ; Federal Agency of Atomic Energy of the Russian Federation ; Russian Academy of Sciences ; Russian Foundation for Basic Research ; National Research Center Kurchatov Institute ; Ministry of Education, Science and Technological Development of Serbia ; Secretaria de Estado de Investigacion, Desarrollo e Innovacion, Programa Consolider-Ingenio 2010, Plan Estatal de Investigacion Cientifica y Tecnica y de Innovacion 2013-2016, Plan de Ciencia, Tecnologia e Innovacion 2013-2017 del Principado de Asturias, S ; Fondo Europeo de Desarrollo Regional, Spain ; Ministry of Science, Technology and Research, Sri Lanka ; ETH Board ; PSI ; SNF ; UniZH ; Canton Zurich ; SER ; Ministry of Science and Technology, Taipei ; Thailand Center of Excellence in Physics ; Institute for the Promotion of Teaching Science and Technology of Thailand ; Special Task Force for Activating Research ; National Science and Technology Development Agency of Thailand ; Scientific and Technical Research Council of Turkey ; Turkish Atomic Energy Authority ; National Academy of Sciences of Ukraine, Ukraine ; State Fund for Fundamental Researches, Ukraine ; Science and Technology Facilities Council, U.K. ; US Department of Energy ; US National Science Foundation ; Marie-Curie program (European Union) ; European Research Council (European Union) ; Horizon 2020 (European Union) ; Leventis Foundation ; A. P. Sloan Foundation ; Alexander von Humboldt Foundation ; Belgian Federal Science Policy Office ; Fonds pour la Formation a la Recherche dans l'Industrie et dans l'Agriculture (FRIA-Belgium) ; Agentschap voor Innovatie door Wetenschap en Technologie (IWT-Belgium) ; F.R.S.-FNRS (Belgium) ; FWO (Belgium) ; Ministry of Education, Youth and Sports (MEYS) of the Czech Republic ; Hungarian Academy of Sciences (Hungary) ; New National Excellence Program UNKP (Hungary) ; NKFIA (Hungary) ; Council of Scientific and Industrial Research, India ; HOMING PLUS program of the Foundation for Polish Science ; European Union, Regional Development Fund ; Mobility Plus program of the Ministry of Science and Higher Education ; National Science Center (Poland) ; National Priorities Research Program by Qatar National Research Fund ; Programa de Excelencia Maria de Maeztu ; Programa Severo Ochoa del Principado de Asturias ; Thalis program ; Aristeia program ; EU-ESF ; Greek NSRF ; Rachadapisek Sompot Fund for Postdoctoral Fellowship, Chulalongkorn University (Thailand) ; Chulalongkorn Academic into Its 2nd Century Project Advancement Project (Thailand) ; Welch Foundation ; Weston Havens Foundation (U.S.A.) ; Estonian Research Council, Estonia: IUT23-4 ; Estonian Research Council, Estonia: IUT23-6 ; Horizon 2020 (European Union): 675440 ; FWO (Belgium): 30820817 ; NKFIA (Hungary): 123842 ; NKFIA (Hungary): 123959 ; NKFIA (Hungary): 124845 ; NKFIA (Hungary): 124850 ; NKFIA (Hungary): 125105 ; National Science Center (Poland): Harmonia 2014/14/M/ST2/00428 ; National Science Center (Poland): Opus 2014/13/B/ST2/02543 ; National Science Center (Poland): 2014/15/B/ST2/03998 ; National Science Center (Poland): 2015/19/B/ST2/02861 ; National Science Center (Poland): Sonata-bis 2012/07/E/ST2/01406 ; Welch Foundation: C-1845 ; An embedding technique is presented to estimate standard model tau tau backgrounds from data with minimal simulation input. In the data, the muons are removed from reconstructed mu mu events and replaced with simulated tau leptons with the same kinematic properties. In this way, a set of hybrid events is obtained that does not rely on simulation except for the decay of the tau leptons. The challenges in describing the underlying event or the production of associated jets in the simulation are avoided. The technique described in this paper was developed for CMS. Its validation and the inherent uncertainties are also discussed. The demonstration of the performance of the technique is based on a sample of proton-proton collisions collected by CMS in 2017 at root s = 13 TeV corresponding to an integrated luminosity of 41.5 fb(-1).

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Open Access

Open Access#42018

Search for Higgsino pair production in pp collisions at root s=13 TeV in final states with large missing transverse momentum and two Higgs bosons decaying via H -> b(b)over bar

Sirunyan, A. M; Tumasyan, A; Adam, W; Ambrogi, F; Asilar, E; Bergauer, T; Brandstetter, J; Brondolin, E

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FWO (Belgium) ; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) ; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) ; Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ) ; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) ; MES (Bulgaria) ; CERN (China) ; CAS (China) ; MoST (China) ; NSFC (China) ; COLCIENCIAS (Colombia) ; MSES (Croatia) ; CSF (Croatia) ; RPF (Cyprus) ; SENESCYT (Ecuador) ; MoER (Estonia) ; ERC IUT (Estonia) ; ERDF (Estonia) ; Academy of Finland (Finland) ; MEC (Finland) ; HIP (Finland) ; CEA (France) ; CNRS/IN2P3 (France) ; BMBF (Germany) ; DFG (Germany) ; HGF (Germany) ; GSRT (Greece) ; OTKA (Hungary) ; NIH (Hungary) ; DAE (India) ; DST (India) ; IPM (Iran) ; SFI (Ireland) ; INFN (Italy) ; MSIP (Republic of Korea) ; NRF (Republic of Korea) ; LAS (Lithuania) ; MOE (Malaysia) ; UM (Malaysia) ; BUAP (Mexico) ; CINVESTAV (Mexico) ; CONACYT (Mexico) ; LNS (Mexico) ; SEP (Mexico) ; UASLP-FAI (Mexico) ; MBIE (New Zealand) ; PAEC (Pakistan) ; MSHE (Poland) ; NSC (Poland) ; FCT (Portugal) ; JINR (Dubna) ; MON (Russia) ; RosAtom (Russia) ; RAS (Russia) ; RFBR (Russia) ; RAEP (Russia) ; MESTD (Serbia) ; SEIDI (Spain) ; CPAN (Spain) ; PCTI (Spain) ; FEDER (Spain) ; Swiss Funding Agencies (Switzerland) ; MST (Taipei) ; ThEPCenter (Thailand) ; IPST (Thailand) ; STAR (Thailand) ; NSTDA (Thailand) ; TAEK (Turkey) ; NASU (Ukraine) ; SFFR (Ukraine) ; STFC (United Kingdom) ; DOE (USA) ; NSF (USA) ; Marie-Curie program ; European Research Council and Horizon Grant (European Union) ; Leventis Foundation ; A. P. Sloan Foundation ; Alexander von Humboldt Foundation ; Belgian Federal Science Policy Office ; Fonds pour la Formation a la Recherche dans l'Industrie et dans l'Agriculture (FRIA-Belgium) ; Ministry of Education, Youth and Sports (MEYS) of the Czech Republic ; Council of Science and Industrial Research, India ; HOMING PLUS program of the Foundation for Polish Science ; European Union ; Regional Development Fund (Poland) ; Mobility Plus program of the Ministry of Science and Higher Education ; National Science Center (Poland) ; National Priorities Research Program by Qatar National Research Fund ; Program a Clarin-COFUND del Principado de Asturias ; Thalis and Aristeia programs ; Greek NSRF ; Rachadapisek Sompot Fund for Postdoctoral Fellowship ; Chulalongkorn University ; Chulalongkorn Academic into Its 2nd Century Project Advancement Project (Thailand) ; Welch Foundation ; Weston Havens Foundation (USA) ; TUBITAK (Turkey) ; Agentschap voor Innovatie door Wetenschap en Technologie (IWT-Belgium) ; EU-ESF ; BMWFW (Austria) ; FWF (Austria) ; FNRS (Belgium) ; European Research Council and Horizon Grant (European Union): 675440 ; National Science Center (Poland): 2014/14/M/ST2/00428 ; National Science Center (Poland): Opus 2014/13/B/ST2/02543 ; National Science Center (Poland): 2014/15/B/ST2/03998 ; National Science Center (Poland): 2015/19/B/ST2/02861 ; National Science Center (Poland): Sonata-bis 2012/07/E/ST2/01406 ; Welch Foundation: C-1845 ; Results are reported from a search for new physics in 13 TeV proton-proton collisions in the final state with large missing transverse momentum and two Higgs bosons decaying via H -> b(b)over bar. The search uses a data sample accumulated by the CMS experiment at the LHC in 2016, corresponding to an integrated luminosity of 35.9 fb(-1). The search is motivated by models based on gauge-mediated supersymmetry breaking, which predict the electroweak production of a pair of Higgsinos, each of which can decay via a cascade process to a Higgs boson and an undetected lightest supersymmetric particle. The observed event yields in the signal regions are consistent with the standard model background expectation obtained from control regions in data. Higgsinos in the mass range 230-770 GeV are excluded at 95% confidence level in the context of a simplified model for the production and decay of approximately degenerate Higgsinos.

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Open Access

Open Access#52018

Search for resonant and nonresonant Higgs boson pair production in the b(b)over-barl nu l nu final state in proton-proton collisions at root s=13 TeV

Sirunyan, A. M; Tumasyan, A; Adam, W; Ambrogi, F; Asilar, E; Bergauer, T; Brandstetter, J; Brondolin, E

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Open Access#62018

Pseudorapidity distributions of charged hadrons in proton-lead collisions at root s(NN)=5:02 and 8.16 TeV

Sirunyan, A. M; Tumasyan, A; Adam, W; Ambrogi, F; Asilar, E; Bergauer, T; Brandstetter, J; Brondolin, E

Sirunyan, A. M; Tumasyan, A; Adam, W; Ambrogi, F; Asilar, E; Bergauer, T; Brandstetter, J; Brondolin, E; Dragicevic, M; Eroe, J; Flechl, M; Friedl, M; Fruehwirth, R; Ghete, V. M; Grossmann, J; Hrubec, J; Jeitler, M; Koeonig, A; Krammer, N; Kraetschmer, I; Liko, D; Madlener, T; Mikulec, I; Pree, E; Rad, N; Rohringer, H; Schieck, J; Schoefbeck, R; Spanring, M; Spitzbart, D; Waltenberger, W; Wittmann, J; Wulz, C. -E; Zarucki, M; Chekhovsky, V; Mossolov, V; Gonzalez, J. Suarez; De Wolf, E. 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BMWFW (Austria) ; FWF (Austria) ; FNRS (Belgium) ; FWO (Belgium) ; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) ; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) ; Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ) ; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) ; MES (Bulgaria) ; CERN ; CAS (China) ; MoST (China) ; NSFC (China) ; COLCIENCIAS (Colombia) ; MSES (Croatia) ; CSF (Croatia) ; RPF (Cyprus) ; SENESCYT (Ecuador) ; MoER (Estonia) ; ERC IUT (Estonia) ; ERDF (Estonia) ; Academy of Finland (Finland) ; MEC (Finland) ; HIP (Finland) ; CEA (France) ; CNRS/IN2P3 (France) ; BMBF (Germany) ; DFG (Germany) ; HGF (Germany) ; GSRT (Greece) ; OTKA (Hungary) ; NIH (Hungary) ; DAE (India) ; DST (India) ; IPM (Iran) ; SFI (Ireland) ; INFN (Italy) ; MSIP (Republic of Korea) ; NRF (Republic of Korea) ; LAS (Lithuania) ; MOE (Malaysia) ; UM (Malaysia) ; BUAP (Mexico) ; CINVESTAV (Mexico) ; CONACYT (Mexico) ; LNS (Mexico) ; SEP (Mexico) ; UASLP-FAI (Mexico) ; MBIE (New Zealand) ; PAEC (Pakistan) ; MSHE (Poland) ; NSC (Poland) ; FCT (Portugal) ; JINR (Dubna) ; MON (Russia) ; RosAtom (Russia) ; RAS (Russia) ; RFBR (Russia) ; RAEP (Russia) ; MESTD (Serbia) ; SEIDI (Spain) ; CPAN (Spain) ; PCTI (Spain) ; FEDER (Spain) ; Swiss Funding Agencies (Switzerland) ; MST (Taipei) ; ThEPCenter (Thailand) ; IPST (Thailand) ; STAR (Thailand) ; NSTDA (Thailand) ; TUBITAK (Turkey) ; TAEK (Turkey) ; NASU (Ukraine) ; SFFR (Ukraine) ; STFC (United Kingdom) ; DOE (U.S.A.) ; NSF (U.S.A.) ; Marie-Curie program ; European Research Council ; Horizon Grant ; Leventis Foundation ; A. P. Sloan Foundation ; Alexander von Humboldt Foundation ; Belgian Federal Science Policy Office ; Fonds pour la Formation a la Recherche dans l'Industrie et dans l'Agriculture (FRIA-Belgium) ; Agentschap voor Innovatie door Wetenschap en Technologie (IWT-Belgium) ; Ministry of Education, Youth and Sports (MEYS) of the Czech Republic ; Council of Science and Industrial Research, India ; HOMING PLUS program of the Foundation for Polish Science ; European Union ; Regional Development Fund ; Mobility Plus program of the Ministry of Science and Higher Education ; National Science Center (Poland) ; National Priorities Research Program by Qatar National Research Fund ; Programa Severo Ochoa del Principado de Asturias ; Thalis program - EU-ESF ; Aristeia program - EU-ESF ; Greek NSRF ; Rachadapisek Sompot Fund for Postdoctoral Fellowship ; Chulalongkorn University ; Chulalongkorn Academic into Its 2nd Century Project Advancement Project (Thailand) ; Welch Foundation ; Weston Havens Foundation (U.S.A.) ; Horizon Grant: 675440 ; National Science Center (Poland): Harmonia 2014/14/M/ST2/00428 ; National Science Center (Poland): Opus 2014/13/B/ST2/02543 ; National Science Center (Poland): 2014/15/B/ST2/03998 ; National Science Center (Poland): 2015/19/B/ST2/02861 ; National Science Center (Poland): Sonata-bis 2012/07/E/ST2/01406 ; Welch Foundation: C-1845 ; The pseudorapidity distributions of charged hadrons in proton-lead collisions at nucleon-nucleon center-of-mass energies root s(NN) = 5.02 and 8.16 TeV are presented. The measurements are based on data samples collected by the CMS experiment at the LHC. The number of primary charged hadrons produced in non-single-diffractive proton-lead collisions is determined in the pseudorapidity range vertical bar eta(lab)vertical bar vertical bar(vertical bar eta cm vertical bar) < 0.5 are 17.1 +/- 0.01 (stat) +/- 0.59 (syst) and 20.10 +/- 0.01 (stat) +/- 0.5(syst) at root s(NN) = 5.02 and 8.16 TeV, respectively. The particle densities per participant nucleon are compared to similar measurements in proton-proton, proton-nucleus, and nucleus-nucleus collisions.

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Open Access

Open Access#72018

Constraintson the double-parton scattering cross section from same-sign W boson pair production in proton-proton collisions at root s=8TeV

Sirunyan, A. M; Tumasyan, A; Adam, W; Ambrogi, F; Asilar, E; Bergauer, T; Brandstetter, J; Brondolin, E

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Gomez; Halkiadakis, E; Heindl, M; Hughes, E; Kaplan, S; Elayavalli, R. Kunnawalkam; Kyriacou, S; Lath, A; Montalvo, R; Nash, K; Osherson, M; Saka, H; Salur, S; Schnetzer, S; Sheffield, D; Somalwar, S; Stone, R; Thomas, S; Thomassen, P; Walker, M; Delannoy, A. G; Foerster, M; Heideman, J; Riley, G; Rose, K; Spanier, S; Thapa, K; Bouhali, O; Hernandez, A. Castaneda; Celik, A; Dalchenko, M; De Mattia, M; Delgado, A; Dildick, S; Eusebi, R; Gilmore, J; Huang, T; Kamon, T; Mueller, R; Pakhotin, Y; Patel, R; Perloff, A; Pernie, L; Rathjens, D; Safonov, A; Tatarinov, A; Ulmer, K. A; Akchurin, N; Damgov, J; De Guio, F; Dudero, P. R; Faulkner, J; Gurpinar, E; Kunori, S; Lamichhane, K; Libeiro, T; Peltola, T; Undleeb, S; Volobouev, I; Greene, S; Gurrola, A; Janjam, R; Johns, W; Maguire, C; Melo, A; Ni, H; Padeken, K; Sheldon, P; Tuo, S; Velkovska, J; Xu, Q; Arenton, M. W; Barria, P; Cox, B; Hirosky, R; Joyce, M; Ledovskoy, A; Li, H; Neu, C; Sinthuprasith, T; Wang, Y; Wolfe, E; Xia, F; Harr, R; Karchin, P. E; Sturdy, J; Zaleski, S; Brodski, M; Buchanan, J; Caillol, C; Dasu, S; Dodd, L; Duric, S; Gomber, B; Grothe, M; Herndon, M; Herve, A; Hussain, U; Klabbers, P; Lanaro, A; Levine, A; Long, K; Loveless, R; Polese, G; Ruggles, T; Savin, A; Smith, N; Smith, W. H; Taylor, D; Woods, N; CMS Collaboration

BMWFW (Austria) ; FWF (Austria) ; FNRS (Belgium) ; FWO (Belgium) ; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) ; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) ; Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ) ; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) ; MES (Bulgaria) ; CERN ; CAS (China) ; MoST (China) ; NSFC (China) ; COLCIENCIAS (Colombia) ; MSES (Croatia) ; CSF (Croatia) ; RPF (Cyprus) ; SENESCYT (Ecuador) ; MoER (Estonia) ; ERC IUT (Estonia) ; ERDF (Estonia) ; Academy of Finland (Finland) ; MEC (Finland) ; HIP (Finland) ; CEA (France) ; CNRS/IN2P3 (France) ; BMBF (Germany) ; DFG (Germany) ; HGF (Germany) ; GSRT (Greece) ; OTKA (Hungary) ; NIH (Hungary) ; DAE (India) ; DST (India) ; IPM (Iran) ; SFI (Ireland) ; INFN (Italy) ; MSIP (Republic of Korea) ; NRF (Republic of Korea) ; LAS (Lithuania) ; MOE (Malaysia) ; UM (Malaysia) ; BUAP (Mexico) ; CINVESTAV (Mexico) ; CONACYT (Mexico) ; LNS (Mexico) ; SEP (Mexico) ; UASLP-FAI (Mexico) ; MBIE (New Zealand) ; PAEC (Pakistan) ; MSHE (Poland) ; NSC (Poland) ; FCT (Portugal) ; JINR (Dubna) ; MON (Russia) ; RosAtom (Russia) ; RAS (Russia) ; RFBR (Russia) ; RAEP (Russia) ; MESTD (Serbia) ; SEIDI (Spain) ; CPAN (Spain) ; PCTI (Spain) ; FEDER (Spain) ; Swiss Funding Agencies (Switzerland) ; MST (Taipei) ; ThEPCenter (Thailand) ; IPST (Thailand) ; STAR (Thailand) ; NSTDA (Thailand) ; TUBITAK (Turkey) ; TAEK (Turkey) ; NASU (Ukraine) ; SFFR (Ukraine) ; STFC (United Kingdom) ; DOE (U.S.A.) ; NSF (U.S.A.) ; Marie-Curie programme ; European Research Council ; Horizon Grant ; Leventis Foundation ; A. P. Sloan Foundation ; Alexander von Humboldt Foundation ; Belgian Federal Science Policy Office ; Fonds pour la Formation a la Recherche dans l'Industrie et dans l'Agriculture (FRIA-Belgium) ; Agentschap voor Innovatie door Wetenschap en Technologie (IWT-Belgium) ; Ministry of Education, Youth and Sports (MEYS) of the Czech Republic ; Council of Science and Industrial Research, India ; HOMING PLUS programme of the Foundation for Polish Science ; European Union, Regional Development Fund ; Mobility Plus programme of the Ministry of Science and Higher Education ; National Science Center (Poland) ; National Priorities Research Program by Qatar National Research Fund ; Programa Severo Ochoa del Principado de Asturias ; Aristeia programme - EU-ESF ; Thalis programme - EU-ESF ; Rachadapisek Sompot Fund for Postdoctoral Fellowship (Thailand) ; Chulalongkorn University (Thailand) ; Chulalongkorn Academic into Its 2nd Century Project Advancement Project (Thailand) ; Welch Foundation (U.S.A.) ; Weston Havens Foundation (U.S.A.) ; Greek NSRF ; Horizon Grant: 675440 ; National Science Center (Poland): Harmonia 2014/14/M/ST2/00428 ; National Science Center (Poland): Opus 2014/13/B/ST2/02543 ; National Science Center (Poland): 2014/15/B/ST2/03998 ; National Science Center (Poland): 2015/19/B/ST2/02861 ; National Science Center (Poland): Sonata-bis 2012/07/E/ST2/01406 ; Welch Foundation (U.S.A.): C-1845 ; A first search for same-sign WW production via double-parton scattering is performed based on proton-proton collision data at a center-of-mass energy of 8TeV using dimuon and electron-muon final states. The search is based on the analysis of data corresponding to an integrated luminosity of 19.7 fb(-1). No significant excess of events is observed above the expected single-parton scattering yields. A 95% confidence level upper limit of 0.32 pb is set on the inclusive cross section for same-sign WW production via the double-parton scattering process. This upper limit is used to place a 95% confidence level lower limit of 12.2mb on the effective double-parton cross section parameter, closely related to the transverse distribution of partons in the proton. This limit on the effective cross section is consistent with previous measurements as well as with Monte Carlo event generator predictions.

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Open Access

Open Access#82018

Search for the pair production of third-generation squarks with two-body decays to a bottom or charm quark and a neutralino in proton-proton collisions at root s=13 TeV

Sirunyan, A. M; Tumasyan, A; Adam, W; Ambrogi, F; Asilar, E; Bergauer, T; Brandstetter, J; Brondolin, E

Sirunyan, A. M; Tumasyan, A; Adam, W; Ambrogi, F; Asilar, E; Bergauer, T; Brandstetter, J; Brondolin, E; Dragicevic, M; Eroe, J; Flechl, M; Friedl, M; Fruehwirth, R; Ghete, V. M; Grossmann, J; Hrubec, J; Jeitler, M; Koenig, A; Krammer, N; Kraetschmer, I; Liko, D; Madlener, T; Mikulec, I; Pree, E; Rabady, D; Rad, N; Rohringer, H; Schieck, J; Schoefbeck, R; Spanring, M; Spitzbart, D; Strauss, J; Waltenberger, W; Wittmann, J; Wulz, C. -E; Zarucki, M; Chekhovsky, V; Gonzalez, J. Suarez; De Wolf, E. A; Di Croce, D; Janssen, X; Lauwers, J; Van Haevermaet, H; Van Mechelen, P; Van Remortel, N; Abu Zeid, S; Blekman, F; D'Hondt, J; De Bruyn, I; De Clercq, J; Deroover, K; Flouris, G; Lontkovskyi, D; Lowette, S; Moortgat, S; Moreels, L; Olbrechts, A; Python, Q; Skovpen, K; Tavernier, S; Van Doninck, W; Van Mulders, P; Van Parijs, I; Brun, H; Clerbaux, B; De Lentdecker, G; Delannoy, H; Fasanella, G; Favart, L; Goldouzian, R; Grebenyuk, A; Karapostoli, G; Lenzi, T; Luetic, J; Maerschalk, T; Marinov, A; Randle-Conde, A; Seva, T; Velde, C. Vander; Vanlaer, P; Vannerom, D; Yonamine, R; Zenoni, F; Zhang, F; Cimmino, A; Cornelis, T; Dobur, D; Fagot, A; Gul, M; Khvastunov, I; Poyraz, D; Roskas, C; Salva, S; Tytgat, M; Verbeke, W; Zaganidis, N; Bakhshiansohi, H; Bondu, O; Brochet, S; Bruno, G; Caudron, A; De Visscher, S; Delaere, C; Delcourt, M; Francois, B; Giammanco, A; Jafari, A; Komm, M; Krintiras, G; Lemaitre, V; Magitteri, A; Mertens, A; Musich, M; Piotrzkowski, K; Quertenmont, L; Marono, M. Vidal; Wertz, S; Beliy, N; Alda Junior, W. L; Alves, F. L; Alves, G. A; Brito, L; Correa Martins Junior, M; Hensel, C; Moraes, A; Pol, M. E; Rebello Teles, P; Belchior Batista Das Chagas, E; Carvalho, W; Chinellato, J; Custodio, A; Da Costa, E. M; Da Silveira, G. G; De Jesus Damiao, D; Fonseca De Souza, S; Huertas Guativa, L. M; Malbouisson, H; Melo De Almeida, M; Mora Herrera, C; Mundim, L; Nogima, H; Santoro, A; Sznajder, A; Tonelli Manganote, E. J; Torres Da Silva De Araujo, F; Vilela Pereira, A; Ahuja, S; Bernardes, C. A; Fernandez Perez Tomei, T. R; Gregores, E. M; Mercadante, P. G; Novaes, S. F; Padula, SandraS; Romero Abad, D; Ruiz Vargas, J. C; Aleksandrov, A; Hadjiiska, R; Iaydjiev, P; Misheva, M; Rodozov, M; Shopova, M; Stoykova, S; Sultanov, G; Dimitrov, A; Glushkov, I; Litov, L; Pavlov, B; Petkov, P; Fang, W; Gao, X; Ahmad, M; Bian, J. G; Chen, G. M; Chen, H. S; Chen, M; Chen, Y; Jiang, C. H; Leggat, D; Liao, H; Liu, Z; Romeo, F; Shaheen, S. M; Spiezia, A; Tao, J; Wang, C; Wang, Z; Yazgan, E; Zhang, H; Zhao, J; Ban, Y; Chen, G; Li, Q; Liu, S; Mao, Y; Qian, S. J; Wang, D; Xu, Z; Avila, C; Cabrera, A; Chaparro Sierra, L. F; Florez, C; Gonzalez Hernandez, C. F; Ruiz Alvarez, J. D; Courbon, B; Godinovic, N; Lelas, D; Puljak, I; Cipriano, P. M. Ribeiro; Sculac, T; Antunovic, Z; Kovac, M; Brigljevic, V; Ferencek, D; Kadija, K; Mesic, B; Starodumov, A; Susa, T; Ather, M. W; Attikis, A; Mavromanolakis, G; Mousa, J; Nicolaou, C; Ptochos, F; Razis, P. A; Rykaczewski, H; Finger, M; Carrera Jarrin, E; Abdelalim, A. A; Mohammed, Y; Salama, E; Dewanjee, R. K; Kadastik, M; Perrini, L; Raidal, M; Tiko, A; Veelken, C; Eerola, P; Pekkanen, J; Voutilainen, M; Harkonen, J; Jarvinen, T; Karimaki, V; Kinnunen, R; Lampen, T; Lassila-Perini, K; Lehti, S; Linden, T; Luukka, P; Tuominen, E; Tuominiemi, J; Tuovinen, E; Talvitie, J; Tuuva, T; Besancon, M; Couderc, F; Dejardin, M; Denegri, D; Faure, J. L; Ferri, F; Ganjour, S; Ghosh, S; Givernaud, A; Gras, P; Monchenault, G. Hamel de; Jarry, P; Kucher, I; Locci, E; Machet, M; Malcles, J; Negro, G; Rander, J; Rosowsky, A; Sahin, M. O; Titov, M; Abdulsalam, A; Antropov, I; Baffioni, S; Beaudette, F; Busson, P; Cadamuro, L; Charlot, C; Cassagnac, R. Granier de; Jo, M; Lisniak, S; Lobanov, A; Blanco, J. Martin; Nguyen, M; Ochando, C; Ortona, G; Paganini, P; Pigard, P; Regnard, S; Salerno, R; Sauvan, J. B; Sirois, Y; Leiton, A. G. Stahl; Strebler, T; Yilmaz, Y; Zabi, A; Zghiche, A; Agram, J. -L; Andrea, J; Bloch, D; Brom, J. -M; Buttignol, M; Chabert, E. C; Chanon, N; Collard, C; Conte, E; Coubez, X; Fontaine, J. -C; Gele, D; Goerlach, U; Jansova, M; Le Bihan, A. -C; Tonon, N; Van Hove, P; Gadrat, S; Beauceron, S; Bernet, C; Boudoul, G; Chierici, R; Contardo, D; Depasse, P; El Mamouni, H; Fay, J; Finco, L; Gascon, S; Gouzevitch, M; Grenier, G; Ille, B; Lagarde, F; Laktineh, I. B; Lethuillier, M; Mirabito, L; Pequegnot, A. L; Perries, S; Popov, A; Sordini, V; Donckt, M. Vander; Viret, S; Toriashvili, T; Lomidze, D; Autermann, C; Beranek, S; Feld, L; Kiesel, M. 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Grados; Grohsjean, A; Gunnellini, P; Harb, A; Hauk, J; Hempel, M; Jung, H; Kalogeropoulos, A; Kasemann, M; Keaveney, J; Kleinwort, C; Korol, I; Kruecker, D; Lange, W; Lelek, A; Lenz, T; Leonard, J; Lipka, K; Lohmann, W; Mankel, R; Melzer-Pellmann, I. -A; Meyer, A. B; Mittag, G; Mnich, J; Mussgiller, A; Ntomari, E; Pitzl, D; Placakyte, R; Raspereza, A; Roland, B; Savitskyi, M; Saxena, P; Shevchenko, R; Spannagel, S; Stefaniuk, N; Van Onsem, G. P; Walsh, R; Wen, Y; Wichmann, K; Wissing, C; Zenaiev, O; Bein, S; Blobel, V; Vignali, M. Centis; Draeger, A. R; Dreyer, T; Garutti, E; Gonzalez, D; Haller, J; Hinzmann, A; Hoffmann, M; Karavdina, A; Klanner, R; Kogler, R; Kovalchuk, N; Kurz, S; Lapsien, T; Marchesini, I; Marconi, D; Meyer, M; Niedziela, M; Nowatschin, D; Pantaleo, F; Peiffer, T; Perieanu, A; Scharf, C; Schleper, P; Schmidt, A; Schumann, S; Schwandt, J; Sonneveld, J; Stadie, H; Steinbrueck, G; Stober, F. M; Stoever, M; Tholen, H; Troendle, D; Usai, E; Vanelderen, L; Vanhoefer, A; Vormwald, B; Akbiyik, M; Barth, C; Baur, S; Butz, E; Caspart, R; Chwalek, T; Colombo, F; De Boer, W; Dierlamm, A; Freund, B; Friese, R; Giffels, M; Gilbert, A; Haitz, D; Hartmann, F; Heindl, S. M; Husemann, U; Kassel, F; Kudella, S; Mildner, H; Mozer, M. U; Mueller, Th; Plagge, M; Quast, G; Rabbertz, K; Schroeder, M; Shvetsov, I; Sieber, G; Simonis, H. J; Ulrich, R; Wayand, S; Weber, M; Weiler, T; Williamson, S; Woehrmann, C; Wolf, R; Anagnostou, G; Daskalakis, G; Geralis, T; Giakoumopoulou, V. A; Kyriakis, A; Loukas, D; Topsis-Giotis, I; Kesisoglou, S; Panagiotou, A; Saoulidou, N; Evangelou, I; Foudas, C; Kokkas, P; Mallios, S; Manthos, N; Papadopoulos, I; Paradas, E; Strologas, J; Triantis, F. A; Csanad, M; Filipovic, N; Pasztor, G; Bencze, G; Hajdu, C; Horvath, D; Hunyadi, A; Sikler, F; Veszpremi, V; Vesztergombi, G; Zsigmond, A. J; Beni, N; Czellar, S; Karancsi, J; Makovec, A; Molnar, J; Szillasi, Z; Bartok, M; Raics, P; Trocsanyi, Z. L; Ujvari, B; Choudhury, S; Komaragiri, J. R; Bahinipati, S; Bhowmik, S; Mal, P; Mandal, K; Nayak, A; Sahoo, D. K; Sahoo, N; Swain, S. K; Bansal, S; Beri, S. B; Bhatnagar, V; Bhawandeep, U; Chawla, R; Dhingra, N; Kalsi, A. K; Kaur, A; Kaur, M; Kumar, R; Kumari, P; Mehta, A; Singh, J. B; Walia, G; Kumar, Ashok; Shah, Aashaq; Bhardwaj, A; Chauhan, S; Choudhary, B. C; Garg, R. B; Keshri, S; Kumar, A; Malhotra, S; Naimuddin, M; Ranjan, K; Sharma, R; Sharma, V; Bhardwaj, R; Bhattacharya, R; Bhattacharya, S; Dey, S; Dutt, S; Dutta, S; Majumdar, N; Modak, A; Mondal, K; Mukhopadhyay, S; Nandan, S; Purohit, A; Roy, A; Roy, D; Chowdhury, S. Roy; Sarkar, S; Sharan, M; Thakur, S; Behera, P. K; Chudasama, R; Dutta, D; Jha, V; Kumar, V; Mohanty, A. K; Netrakanti, P. K; Pant, L. M; Shukla, P; Topkar, A; Aziz, T; Dugad, S; Mahakud, B; Mitra, S; Mohanty, G. 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Austrian Federal Ministry of Science, Research and Economy ; Austrian Science Fund ; Belgian Fonds De La Recherche Scientifique - FNRS ; Fonds Wetenschappelijk Onderzoek ; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) ; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) ; Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ) ; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) ; Bulgarian Ministry of Education and Science ; CERN ; Chinese Academy of Sciences ; Ministry of Science and Technology of the People's Republic of China ; National Natural Science Foundation of China ; Colombian Funding Agency (COLCIENCIAS) ; Croatian Ministry of Science, Education and Sports ; Croatian Science Foundation ; Research Promotion Foundation, Cyprus ; National Secretary of Higher Education, Science, Technology and Innovation, Ecuador ; Ministry of Education and Research, Estonian Research Council ; European Regional Development Fund, Estonia ; Academy of Finland ; Ministry of Education and Culture, Finland ; Helsinki Institute of Physics ; Institut National de Physique Nucleaire et de Physique des Particules/CNRS ; Commissariat a l'Energie Atomique et aux Energies Alternatives, France ; Bundesministerium fur Bildung und Forschung ; Deutsche Forschungsgemeinschaft ; Helmholtz Gemeinschaft Deutscher Forschungszentren, Germany ; General Secretariat for Research and Technology, Greece ; National Scientific Research Foundation ; National Innovation Office, Hungary ; Department of Atomic Energy, Government of India ; Department of Science and Technology, India ; Institute for Studies in Theoretical Physics and Mathematics, Iran ; Science Foundation Ireland ; Istituto Nazionale di Fisica Nucleare, Italy ; Ministry of Science, ICT and Future Planning ; National Research Foundation of Korea (NRF), Republic of Korea ; Lithuanian Academy of Sciences ; Ministry of Education ; University of Malaya (Malaysia) ; BUAP ; CINVESTAV ; CONACYT ; LNS ; SEP ; UASLP-FAI ; Ministry of Business, Innovation and Employment, New Zealand ; Pakistan Atomic Energy Commission ; Ministry of Science and Higher Education ; National Science Centre, Poland ; Fundacao para a Ciencia e a Tecnologia, Portugal ; JINR, Dubna ; Ministry of Education and Science of the Russian Federation ; Federal Agency of Atomic Energy of the Russian Federation ; Russian Academy of Sciences ; Russian Foundation for Basic Research ; Russian Competitiveness Program of NRNU MEPhI ; Ministry of Education, Science and Technological Development of Serbia ; Secretaria de Estado de Investigacion, Desarrollo e Innovacion, Programa Consolider-Ingenio ; Plan de Ciencia, Tecnologia e Innovacion ; Fondo Europeo de Desarrollo Regional, Spain ; ETH Board ; ETH Zurich ; PSI ; SNF ; UniZH ; Canton Zurich ; SER ; Ministry of Science and Technology of Taiwan, Taipei ; Thailand Center of Excellence in Physics ; Institute for the Promotion of Teaching Science and Technology of Thailand ; Special Task Force for Activating Research ; National Science and Technology Development Agency of Thailand ; Scientific and Technical Research Council of Turkey ; Turkish Atomic Energy Authority ; National Academy of Sciences of Ukraine ; State Fund for Fundamental Researches, Ukraine ; Science and Technology Facilities Council, UK ; U.S. Department of Energy ; US National Science Foundation ; Marie-Curie programme ; European Research Council and Horizon (European Union) ; Leventis Foundation ; Alfred P. Sloan Foundation ; Alexander von Humboldt Foundation ; Belgian Federal Science Policy Office ; Fonds pour la Formation a la Recherche dans l'Industrie et dans l'Agriculture (FRIA-Belgium) ; Agentschap voor Innovatie door Wetenschap en Technologie (IWT-Belgium) ; Ministry of Education, Youth and Sports (MEYS) of the Czech Republic ; Council of Scientific and Industrial Research, India ; HOMING PLUS programme of the Foundation for Polish Science ; European Union ; Regional Development Fund ; Mobility Plus programme of the Ministry of Science and Higher Education ; National Science Centre (Poland) ; National Priorities Research Program by Qatar National Research Fund ; Programa Clarin-COFUND del Principado de Asturias ; Thalis programme ; Aristeia programme ; EU-ESF ; Greek NSRF ; Rachadapisek Sompot Fund for Postdoctoral Fellowship ; Chulalongkorn University ; Chulalongkorn Academic into Its 2nd Century Project Advancement Project (Thailand) ; Welch Foundation ; Ministry of Education and Research, Estonian Research Council: IUT23-4 ; Ministry of Education and Research, Estonian Research Council: IUT23-6 ; European Research Council and Horizon (European Union): 675440 ; National Science Centre (Poland): Harmonia 2014/14/M/ST2/00428 ; National Science Centre (Poland): Opus 2014/13/B/ST2/02543 ; National Science Centre (Poland): 2014/15/B/ST2/03998 ; National Science Centre (Poland): 2015/19/B/ST2/02861 ; National Science Centre (Poland): Sonata-bis 2012/07/E/ST2/01406 ; Welch Foundation: C-1845 ; Results are presented from a search for the pair production of third-generation squarks in proton-proton collision events with two-body decays to bottom or charm quarks and a neutralino, which produces a significant imbalance in the transverse momentum. The search is performed using a sample of proton-proton collision data at root s = 13 TeV recorded by the CMS experiment at the LHC, corresponding to an integrated luminosity of 35.9fb(-1). No statistically significant excess of events is observed beyond the expected contribution from standard model processes. Exclusion limits are set in the context of simplified models of bottom or top squark pair production. Models with bottom squark masses up to 1220 GeV are excluded at 95% confidence level for light neutralinos, and models with top squark masses of 510 GeV are excluded assuming that the mass splitting between the top squark and the neutralino is small. (C) 2018 The Author. Published by Elsevier B.V.

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Open Access

Open Access#92018

Measurements of the pp -> ZZ production cross section and the Z -> 4l branching fraction, and constraints on anomalous triple gauge couplings at root s=13TeV

Sirunyan, A. M; Tumasyan, A; Adam, W; Ambrogi, F; Asilar, E; Bergauer, T; Brandstetter, J; Brondolin, E

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T; Ferbel, T; Galanti, M; Garcia-Bellido, A; Han, J; Hindrichs, O; Khukhunaishvili, A; Lo, K. H; Tan, P; Verzetti, M; Ciesielski, R; Goulianos, K; Mesropian, C; Agapitos, A; Chou, J. P; Gershtein, Y; Espinosa, T. A. Gomez; Halkiadakis, E; Heindl, M; Hughes, E; Kaplan, S; Elayavalli, R. Kunnawalkam; Kyriacou, S; Lath, A; Montalvo, R; Nash, K; Osherson, M; Saka, H; Salur, S; Schnetzer, S; Sheffield, D; Somalwar, S; Stone, R; Thomas, S; Thomassen, P; Walker, M; Delannoy, A. G; Foerster, M; Heideman, J; Riley, G; Rose, K; Spanier, S; Thapa, K; Bouhali, O; Hernandez, A. Castaneda; Celik, A; Dalchenko, M; De Mattia, M; Delgado, A; Dildick, S; Eusebi, R; Gilmore, J; Huang, T; Kamon, T; Mueller, R; Pakhotin, Y; Patel, R; Perloff, A; Pernie, L; Rathjens, D; Safonov, A; Tatarinov, A; Ulmer, K. A; Akchurin, N; Damgov, J; De Guio, F; Dudero, P. 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Open Access

Open Access#102018

Search for electroweak production of charginos and neutralinos in multilepton final states in proton-proton collisions at root s=13 TeV

Sirunyan, A. M; Tumasyan, A; Adam, W; Ambrogi, F; Asilar, E; Bergauer, T; Brandstetter, J; Brondolin, E

Sirunyan, A. M; Tumasyan, A; Adam, W; Ambrogi, F; Asilar, E; Bergauer, T; Brandstetter, J; Brondolin, E; Dragicevic, M; Eroe, J; Flechl, M; Friedl, M; Fruehwirth, R; Ghete, V. M; Grossmann, J; Hrubec, J; Jeitler, M; Koenig, A; Krammer, N; Kraetschmer, I; Liko, D; Madlener, T; Mikulec, I; Pree, E; Rabady, D; Rad, N; Rohringer, H; Schieck, J; Schoefbeck, R; Spanring, M; Spitzbart, D; Strauss, J; Waltenberger, W; Wittmann, J; Wulz, C. -E; Zarucki, M; Chekhovsky, V; Mossolov, V; Gonzalez, J. Suarez; De Wolf, E. 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BMWFW (Austria) ; FWF (Austria) ; FNRS (Belgium) ; FWO (Belgium) ; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) ; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) ; Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ) ; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) ; MES (Bulgaria) ; CERN ; CAS (China) ; MoST (China) ; NSFC (China) ; COLCIENCIAS (Colombia) ; MSES (Croatia) ; CSF (Croatia) ; RPF (Cyprus) ; SENESCYT (Ecuador) ; MoER (Estonia) ; ERC IUT (Estonia) ; ERDF (Estonia) ; Academy of Finland (Finland) ; MEC (Finland) ; HIP (Finland) ; CEA (France) ; CNRS/IN2P3 (France) ; BMBF (Germany) ; DFG (Germany) ; HGF (Germany) ; GSRT (Greece) ; OTKA (Hungary) ; NIH (Hungary) ; DAE (India) ; DST (India) ; IPM (Iran) ; SFI (Ireland) ; INFN (Italy) ; MSIP (Republic of Korea) ; NRF (Republic of Korea) ; LAS (Lithuania) ; MOE (Malaysia) ; UM (Malaysia) ; BUAP (Mexico) ; CINVESTAV (Mexico) ; CONACYT (Mexico) ; LNS (Mexico) ; SEP (Mexico) ; UASLP-FAI (Mexico) ; MBIE (New Zealand) ; PAEC (Pakistan) ; MSHE (Poland) ; NSC (Poland) ; FCT (Portugal) ; JINR (Dubna) ; MON (Russia) ; RosAtom (Russia) ; RAS (Russia) ; RFBR (Russia) ; RAEP (Russia) ; MESTD (Serbia) ; SEIDI (Spain) ; CPAN (Spain) ; PCTI (Spain) ; FEDER (Spain) ; Swiss Funding Agencies (Switzerland) ; MST (Taipei) ; ThEPCenter (Thailand) ; IPST (Thailand) ; STAR (Thailand) ; NSTDA (Thailand) ; TUBITAK (Turkey) ; TAEK (Turkey) ; NASU (Ukraine) ; SFFR (Ukraine) ; STFC (United Kingdom) ; DOE (U.S.A.) ; NSF (U.S.A.) ; Marie-Curie program ; European Research Council ; Horizon Grant ; Leventis Foundation ; A. P. Sloan Foundation ; Alexander von Humboldt Foundation ; Belgian Federal Science Policy Office ; Fonds pour la Formation a la Recherche dans l'Industrie et dans l'Agriculture (FRIA-Belgium) ; Agentschap voor Innovatie door Wetenschap en Technologie (IWT-Belgium) ; Ministry of Education, Youth and Sports (MEYS) of the Czech Republic ; Council of Science and Industrial Research, India ; HOMING PLUS program of the Foundation for Polish Science ; European Union ; Regional Development Fund ; Mobility Plus program of the Ministry of Science and Higher Education ; National Science Center (Poland) ; National Priorities Research Program by Qatar National Research Fund ; Programa Clarin-COFUND del Principado de Asturias ; Thalis program ; Aristeia program ; EU-ESF ; Greek NSRF ; Rachadapisek Sompot Fund for Postdoctoral Fellowship, Chulalongkorn University ; Chulalongkorn Academic into Its 2nd Century Project Advancement Project (Thailand) ; Welch Foundation ; Weston Havens Foundation (U.S.A.) ; Horizon Grant: 675440 ; National Science Center (Poland): Harmonia 2014/14/M/ST2/00428 ; National Science Center (Poland): Opus 2014/13/B/ST2/02543 ; National Science Center (Poland): 2014/15/B/ST2/03998 ; National Science Center (Poland): 2015/19/B/ST2/02861 ; National Science Center (Poland): Sonata-bis 2012/07/E/ST2/01406 ; Welch Foundation: C-1845 ; Results are presented from a search for the direct electroweak production of charginos and neutralinos in signatures with either two or more leptons (electrons or muons) of the same electric charge, or with three or more leptons, which can include up to two hadronically decaying tau leptons. The results are based on a sample of proton proton collision data collected at root s = 13 TeV, recorded with the CMS detector at the LHC, corresponding to an integrated luminosity of 35.9 fb(-1). The observed event yields are consistent with the expectations based on the standard model. The results are interpreted in simplified models of supersymmetry describing various scenarios for the production and decay of charginos and neutralinos. Depending on the model parameters chosen, mass values between 180 GeV and 1150 GeV are excluded at 95% CL. These results significantly extend the parameter space probed for these particles in searches at the LHC. In addition, results are presented in a form suitable for alternative theoretical interpretations.

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Open Access

Open Access#112017

Search for direct production of super symmetric partners of the top quark in the all-jets final state in proton-proton collisions at root s=13 TeV

Sirunyan, A. M; Tumasyan, A; Adam, W; Ambrogi, F; Asilar, E; Bergauer, T; Brandstetter, J; Brondolin, E

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BMWFW (Austria) ; FWF (Austria) ; FNRS (Belgium) ; FWO (Belgium) ; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) ; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) ; Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ) ; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) ; MES (Bulgaria) ; CERN ; CAS (China) ; MoST (China) ; NSFC (China) ; COLCIENCIAS (Colombia) ; MSES (Croatia) ; CSF (Croatia) ; RPF (Cyprus) ; SENESCYT (Ecuador) ; MoER (Estonia) ; ERC IUT (Estonia) ; ERDF (Estonia) ; Academy of Finland (Finland) ; MEC (Finland) ; HIP (Finland) ; CEA (France) ; CNRS/IN2P3 (France) ; BMBF (Germany) ; DFG (Germany) ; HGF (Germany) ; GSRT (Greece) ; OTKA (Hungary) ; NIH (Hungary) ; DAE (India) ; DST (India) ; IPM (Iran) ; SFI (Ireland) ; INFN (Italy) ; MSIP (Republic of Korea) ; NRF (Republic of Korea) ; LAS (Lithuania) ; MOE (Malaysia) ; UM (Malaysia) ; BUAP (Mexico) ; CINVESTAV (Mexico) ; CONACYT (Mexico) ; LNS (Mexico) ; SEP (Mexico) ; UASLP-FAI (Mexico) ; MBIE (New Zealand) ; PAEC (Pakistan) ; MSHE (Poland) ; NSC (Poland) ; FCT (Portugal) ; JINR (Dubna) ; MON (Russia) ; RosAtom (Russia) ; RAS (Russia) ; RFBR (Russia) ; RAEP (Russia) ; MESTD (Serbia) ; SEIDI (Spain) ; CPAN (Spain) ; PCTI (Spain) ; FEDER (Spain) ; Swiss Funding Agencies (Switzerland) ; MST (Taipei) ; ThEPCenter (Thailand) ; IPST (Thailand) ; STAR (Thailand) ; NSTDA (Thailand) ; TUBITAK (Turkey) ; TAEK (Turkey) ; NASU (Ukraine) ; SFFR (Ukraine) ; STFC (United Kingdom) ; DOE (U.S.A.) ; NSF (U.S.A.) ; Marie-Curie program ; European Research Council ; Leventis Foundation ; A. P. Sloan Foundation ; Alexander von Humboldt Foundation ; Belgian Federal Science Policy Office ; Fonds pour la Formation a la Recherche dans l'Industrie et dans l'Agriculture (FRIA-Belgium) ; Agentschap voor Innovatie door Wetenschap en Technologie (IWT-Belgium) ; Ministry of Education, Youth and Sports (MEYS) of the Czech Republic ; Council of Science and Industrial Research, India ; HOMING PLUS of the Foundation for Polish Science ; European Union ; Ministry of Science and Higher Education ; National Science Center (Poland) ; National Priorities Research Program by Qatar National Research Fund ; Programa Clarin-COFUND del Principado de Asturias ; Thalis Program ; EU-ESF ; Greek NSRF ; Rachadapisek Sompot Fund for Postdoctoral Fellowship ; Chulalongkorn University ; Chulalongkorn Academic into Its 2nd Century Project Advancement Project (Thailand) ; Welch Foundation ; Aristeia program ; National Science Center (Poland): Harmonia 2014/14/M/ST2/00428 ; National Science Center (Poland): Opus 2014/13/B/ST2/02543 ; National Science Center (Poland): 2014/15/B/ST2/03998 ; National Science Center (Poland): 2015/19/B/ST2/02861 ; National Science Center (Poland): Sonata-bis 2012/07/E/ST2/01406 ; Welch Foundation: C-1845 ; European Union: 675440 ; A search for direct production of top squark pairs in events with jets and large transverse momentum imbalance is presented. The data are based on proton-proton collisions at a center-of-mass energy of 13 TeV, collected with the CMS detector in 2016 at the CERN LHC, and correspond to an integrated luminosity of 35.9 fb(-1). The search considers a variety of R-parity conserving supersymmetric models, including ones for which the top squark and neutralino masses are nearly degenerate. Specialized jet reconstruction tools are developed to exploit the unique characteristics of the signal topologies. With no significant excess of events observed above the standard model expectations, upper limits are set on the direct top squark pair production cross section in the context of simplified supersymmetric models for various decay hypotheses. Models with larger differences in mass between the top squark and neutralino are probed for masses up to 1040 and 500 GeV, respectively, whereas models with a more compressed mass hierarchy are probed up to 660 and 610 GeV, respectively. The smallest mass difference probed is for masses near to 550 and 540 GeV, respectively.

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Open Access

Open Access#122017

Constraints on anomalous Higgs boson couplings using production and decay information in the four-lepton final state

Sirunyan, A. M; Collaboration, C. M. S; Tumasyan, A; Adam, W; Ambrogi, F; Asilar, E; Bergauer, T; Brandstetter, J

Sirunyan, A. M; Collaboration, C. M. S; Tumasyan, A; Adam, W; Ambrogi, F; Asilar, E; Bergauer, T; Brandstetter, J; Brondolin, E; Dragicevic, M; Ero, J; Flechl, M; Friedl, M; Fruhwirth, R; Ghete, V. M; Grossmann, J; Hrubec, J; Jeitler, M; Konig, A; Krammer, N; Kratschmer, I; Liko, D; Madlener, T; Mikulec, I; Pree, E; Rabady, D; Rad, N; Rohringer, H; Schieck, J; Schofbeck, R; Spanring, M; Spitzbart, D; Waltenberger, W; Wittmann, J; Wulz, C. E; Zarucki, M; Chekhovsky, V; Mossolov, V; Gonzalez, J. Suarez; DeWolf, E. 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Open Access#132017

Search for heavy resonances that decay into a vector boson and a Higgs boson in hadronic final states at root s=13TeV

Sirunyan, A. M; Tumasyan, A; Adam, W; Ambrogi, E; Asilar, E; Bergauer, T; Brandstetter, J; Brondolin, E

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BMWFW (Austria) ; FWF (Austria) ; FNRS (Belgium) ; FWO(Belgium) ; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) ; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) ; Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ) ; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) ; MES (Bulgaria) ; CERN (China) ; CAS (China) ; MoST (China) ; NSFC (China) ; COLCIENCIAS (Colombia) ; MSES (Croatia) ; CSF (Croatia) ; RPF (Cyprus) ; SENESCYT (Ecuador) ; MoER (Estonia) ; ERC IUT (Estonia) ; ERDF (Estonia) ; Academy of Finland (Finland) ; MEC (Finland) ; HIP (Finland) ; CEA (France) ; CNRS/IN2P3 (France) ; BMBF (Germany) ; DFG (Germany) ; HGF (Germany) ; GSRT (Greece) ; OTKA (Hungary) ; NIH (Hungary) ; DAE (India) ; DST (India) ; IPM (Iran) ; SFI (Ireland) ; INFN (Italy) ; MSIP (Republic of Korea) ; NRF (Republic of Korea) ; LAS (Lithuania) ; MOE (Malaysia) ; UM(Malaysia) ; BUAP (Mexico) ; CINVESTAV (Mexico) ; CONACYT (Mexico) ; LNS (Mexico) ; SEP (Mexico) ; UASLP-FAI (Mexico) ; MBIE(New Zealand) ; PAEC(Pakistan) ; MSHE (Poland) ; NSC (Poland) ; FCT (Portugal) ; JINR (Dubna) ; MON (Russia) ; RosAtom (Russia) ; RAS (Russia) ; RFBR (Russia) ; RAEP (Russia) ; MESTD (Serbia) ; SEIDI (Spain) ; CPAN (Spain) ; PCTI (Spain) ; FEDER (Spain) ; Swiss Funding Agency (Switzerland) ; MST (Taipei) ; ThEPCenter (Thailand) ; IPST (Thailand) ; STAR (Thailand) ; NSTDA (Thailand) ; TUBITAK (Turkey) ; TAEK (Turkey) ; NASU (Ukraine) ; SFFR (Ukraine) ; STFC (UK) ; DOE (USA) ; NSF (USA) ; European Research Council and Horizon ; European Union, Regional Development Fund ; Mobility Plus program of the Ministry of Science and Higher Education ; National Science Center (Poland) ; National Priorities Research Program by Qatar National Research Fund ; Programa Clarin-COFUND del Principado de Asturias ; Thalis program ; Aristeia program ; EUESF ; Greek NSRF ; Rachadapisek Sompot Fund for Postdoctoral Fellowship ; Chulalongkorn University ; Chulalongkorn Academic into its 2nd Century Project Advancement Project (Thailand) ; Welch Foundation ; Marie-Curie program ; Leventis Foundation ; A. P. Sloan Foundation ; Alexander von Humboldt Foundation ; Belgian Federal Science Policy Office ; Fonds pour la Formation a la Recherche dans l'Industrie et dans l'Agriculture (FRIA-Belgium) ; Agentschap voor Innovatie door Wetenschap en Technologie (IWT-Belgium) ; Ministry of Education, Youth and Sports (MEYS) of the Czech Republic ; Council of Science and Industrial Research, India ; HOMING PLUS program of the Foundation for Polish Science ; European Research Council and Horizon: 675440 ; National Science Center (Poland): Harmonia 2014/14/M/ST2/00428 ; National Science Center (Poland): Opus 2014/13/B/ST2/02543 ; National Science Center (Poland): 2014/15/B/ST2/03998 ; National Science Center (Poland): 2015/19/B/ST2/02861 ; National Science Center (Poland): Sonata-bis 2012/07/ E/ST2/01406 ; Welch Foundation: C-1845 ; A search for heavy resonances with masses above 1 TeV, decaying to final states containing a vector boson and a Higgs boson, is presented. The search considers hadronic decays of the vector boson, and Higgs boson decays to b quarks. The decay products are highly boosted, and each collimated pair of quarks is reconstructed as a single, massive jet. The analysis is performed using a data sample collected in 2016 by the CMS experiment at the LHC in proton-proton collisions at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 35.9 fb(-1). The data are consistent with the background expectation and are used to place limits on the parameters of a theoretical model with a heavy vector triplet. In the benchmark scenario with mass-degenerate W' and Z' bosons decaying predominantly to pairs of standard model bosons, for the first time heavy resonances for masses as high as 3.3 TeV are excluded at 95% confidence level, setting the most stringent constraints to date on such states decaying into a vector boson and a Higgs boson.

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Open Access

Open Access#142017

Search for electroweak production of charginos and neutralinos in WH events in proton-proton collisions at root s=13 TeV

Sirunyan, A. M; Tumasyan, A; Adam, W; Ambrogi, F; Asilar, E; Bergauer, T; Brandstetter, J; Brondolin, E

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BMWFW (Austria) ; FWF (Austria) ; FNRS (Belgium) ; FWO (Belgium) ; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) ; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) ; Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ) ; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) ; MES (Bulgaria) ; CERN (China) ; CAS (China) ; MoST (China) ; NSFC (China) ; COLCIENCIAS (Colombia) ; MSES (Croatia) ; CSF (Croatia) ; RPF (Cyprus) ; SENESCYT (Ecuador) ; MoER (Estonia) ; ERC IUT (Estonia) ; ERDF (Estonia) ; Academy of Finland (Finland) ; MEC (Finland) ; HIP (Finland) ; CEA (France) ; CNRS/IN2P3 (France) ; BMBF (Germany) ; DFG (Germany) ; HGF (Germany) ; GSRT (Greece) ; OTKA (Hungary) ; NIH (Hungary) ; DAE (India) ; DST (India) ; IPM (Iran) ; SFI (Ireland) ; INFN (Italy) ; MSIP (Republic of Korea) ; NRF (Republic of Korea) ; LAS (Lithuania) ; MOE (Malaysia) ; UM (Malaysia) ; BUAP (Mexico) ; CINVESTAV (Mexico) ; CONACYT (Mexico) ; LNS (Mexico) ; SEP (Mexico) ; UASLP-FAI (Mexico) ; MBIE (New Zealand) ; PAEC (Pakistan) ; MSHE (Poland) ; NSC (Poland) ; FCT (Portugal) ; JINR (Dubna) ; MON (Russia) ; RosAtom (Russia) ; RAS (Russia) ; RFBR (Russia) ; RAEP (Russia) ; MESTD (Serbia) ; SEIDI (Spain) ; CPAN (Spain) ; PCTI (Spain) ; FEDER (Spain) ; Swiss Funding Agencies (Switzerland) ; MST (Taipei) ; ThEPCenter (Thailand) ; IPST (Thailand) ; STAR (Thailand) ; NSTDA (Thailand) ; TUBITAK (Turkey) ; TAEK (Turkey) ; NASU (Ukraine) ; SFFR (Ukraine) ; STFC (United Kingdom) ; DOE (U.S.A.) ; NSF (U.S.A.) ; Marie-Curie program (European Union) ; European Research Council (European Union) ; Horizon 2020 Grant (European Union) ; Leventis Foundation ; A.P. Sloan Foundation ; Alexander von Humboldt Foundation ; Belgian Federal Science Policy Office ; Fonds pour la Formation a la Recherche dans l'Industrie et dans l'Agriculture (FRIA-Belgium) ; Agentschap voor Innovatie door Wetenschap en Technologie (IWT-Belgium) ; Ministry of Education, Youth and Sports (MEYS) of the Czech Republic ; Council of Science and Industrial Research, India ; HOMING PLUS program of the Foundation ; European Union ; Regional Development Fund ; Mobility Plus program of the Ministry of Science and Higher Education ; National Science Center (Poland) ; National Priorities Research Program by Qatar National Research Fund ; Programa Clarin-COFUND del Principado de Asturias ; Thalis ; Aristeia programs ; EU-ESF ; Greek NSRF ; Rachadapisek Sompot Fund ; Chulalongkorn University ; Chulalongkorn Academic into Its 2nd Century Project Advancement Project (Thailand) ; Welch Foundation ; Horizon 2020 Grant (European Union): 675440 ; National Science Center (Poland): Harmonia 2014/14/M/ST2/00428 ; National Science Center (Poland): Opus 2014/13/B/ST2/02543 ; National Science Center (Poland): 2014/15/B/ST2/03998 ; National Science Center (Poland): 2015/19/B/ST2/02861 ; National Science Center (Poland): Sonata-bis 2012/07/E/ST2/01406 ; Welch Foundation: C-1845 ; Results are reported from a search for physics beyond the standard model in proton-proton collision events with a charged lepton (electron or muon), two jets identi fi ed as originating from a bottom quark decay, and signi fi cant imbalance in the transverse momentum. The search was performed using a data sample corresponding to 35.9 fb(-1), collected by the CMS experiment in 2016 at root s = 13 TeV. Events with this signature can arise, for example, from the electroweak production of gauginos, which are predicted in models based on supersymmetry. The event yields observed in data are consistent with the estimated standard model backgrounds. Limits are obtained on the cross sections for chargino-neutralino ((chi) over tilde (+/-)(1) (chi) over tilde (0)(2)) production in a simplified model of supersymmetry with the decays (chi) over tilde (+/-)(1) -> W-(chi) over tilde1(+/-)0 and (chi) over tilde (0)(2) -> H-(chi) over tilde1(0). Values of m((chi) over tilde1 +/-) between 220 and 490 GeV are excluded at 95% confidence level by this search when the (chi) over tilde (0)(1) is massless, and values of m((chi) over tilde 10) are excluded up to 110 GeV for m((chi) over tilde1 +/-) approximate to 450 GeV.

BASE

Open Access

Open Access#152019

Search for top quark partners with charge 5/3 in the same-sign dilepton and single-lepton final states in proton-proton collisions at root s=13 TeV

Sirunyan, A. M; Tumasyan, A; Adam, W; Ambrogi, F; Asilar, E; Bergauer, T; Brandstetter, J; Dragicevic, M

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BMWFW (Austria) ; FWF (Austria) ; FNRS (Belgium) ; FWO (Belgium) ; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) ; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) ; Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ) ; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) ; MES (Bulgaria) ; CERN ; CAS (China) ; MoST (China) ; NSFC (China) ; COLCIENCIAS (Colombia) ; MSES (Croatia) ; CSF (Croatia) ; RPF (Cyprus) ; SENESCYT (Ecuador) ; MoER (Estonia) ; ERC IUT (Estonia) ; ERDF (Estonia) ; Academy of Finland (Finland) ; MEC (Finland) ; HIP (Finland) ; CEA (France) ; CNRS/IN2P3 (France) ; BMBF (Germany) ; DFG (Germany) ; HGF (Germany) ; GSRT (Greece) ; NKFIA (Hungary) ; DAE (India) ; DST (India) ; IPM (Iran) ; SFI (Ireland) ; INFN (Italy) ; MSIP (Republic of Korea) ; NRF (Republic of Korea) ; LAS (Lithuania) ; MOE (Malaysia) ; UM (Malaysia) ; BUAP (Mexico) ; CINVESTAV (Mexico) ; CONACYT (Mexico) ; LNS (Mexico) ; SEP (Mexico) ; UASLP-FAI (Mexico) ; MBIE (New Zealand) ; PAEC (Pakistan) ; MSHE (Poland) ; NSC (Poland) ; FCT (Portugal) ; JINR (Dubna) ; MON (Russia) ; RosAtom (Russia) ; RAS (Russia) ; RFBR (Russia) ; MESTD (Serbia) ; SEIDI (Spain) ; CPAN (Spain) ; PCTI (Spain) ; FEDER (Spain) ; Swiss Funding Agencies (Switzerland) ; MST (Taipei) ; ThEPCenter (Thailand) ; IPST (Thailand) ; STAR (Thailand) ; NSTDA (Thailand) ; TUBITAK (Turkey) ; TAEK (Turkey) ; NASU (Ukraine) ; SFFR (Ukraine) ; STFC (United Kingdom) ; DOE (U.S.A.) ; NSF (U.S.A.) ; Marie-Curie programme (European Union) ; European Research Council (European Union) ; Horizon 2020 Grant (European Union) ; Leventis Foundation ; A. P. Sloan Foundation ; Alexander von Humboldt Foundation ; Belgian Federal Science Policy Office ; Fonds pour la Formation a la Recherche dans l'Industrie et dans l'Agriculture (FRIA-Belgium) ; Agentschap voor Innovatie door Wetenschap en Technologie (IWT-Belgium) ; F.R.S.-FNRS (Belgium) under the Excellence of Science - EOS - be.h project ; FWO (Belgium) under the Excellence of Science - EOS - be.h project ; Ministry of Education, Youth and Sports (MEYS) of the Czech Republic ; Lendulet (Momentum) Programme of the Hungarian Academy of Sciences ; Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences ; New National Excellence Program UNKP ; NKFIA research grants (Hungary) ; Council of Science and Industrial Research, India ; HOMING PLUS programme of the Foundation for Polish Science ; European Union, Regional Development Fund ; Mobility Plus programme of the Ministry of Science and Higher Education ; National Science Center (Poland) ; National Priorities Research Program by Qatar National Research Fund ; Programa Estatal de Fomento de la Investigacion Cientifica y Tecnica de Excelencia Maria de Maeztu ; Programa Severo Ochoa del Principado de Asturias ; Thalis programme - EU-ESF ; Aristeia programme - EU-ESF ; Greek NSRF ; Rachadapisek Sompot Fund for Postdoctoral Fellowship, Chulalongkorn University (Thailand) ; Chulalongkorn Academic into Its 2nd Century Project Advancement Project (Thailand) ; Welch Foundation ; Weston Havens Foundation (U.S.A.) ; European Research Council (European Union): 675440 ; Horizon 2020 Grant (European Union): 675440 ; F.R.S.-FNRS (Belgium) under the Excellence of Science - EOS - be.h project: 30820817 ; FWO (Belgium) under the Excellence of Science - EOS - be.h project: 30820817 ; NKFIA research grants (Hungary): 123842 ; NKFIA research grants (Hungary): 123959 ; NKFIA research grants (Hungary): 124845 ; NKFIA research grants (Hungary): 124850 ; NKFIA research grants (Hungary): 125105 ; National Science Center (Poland): Harmonia 2014/14/M/ST2/00428 ; National Science Center (Poland): Opus 2014/13/B/ST2/02543 ; National Science Center (Poland): 2014/15/B/ST2/03998 ; National Science Center (Poland): 2015/19/B/ST2/02861 ; National Science Center (Poland): Sonata-bis 2012/07/E/ST2/01406 ; Programa Estatal de Fomento de la Investigacion Cientifica y Tecnica de Excelencia Maria de Maeztu: MDM-2015-0509 ; Welch Foundation: C-1845 ; A search for the pair production of heavy fermionic partners of the top quark with charge 5/3 (X-5/3) is performed in proton-proton collisions at a center-of-mass energy of 13 TeV with the CMS detector at the CERN LHC. The data sample analyzed corresponds to an integrated luminosity of 35.9 fb(-1). The X-5/3 quark is assumed always to decay into a top quark and a W boson. Both the right-handed and left-handed X-5/3 couplings to the W boson are considered. Final states with either a pair of same-sign leptons or a single lepton are studied. No significant excess of events is observed above the expected standard model background. Lower limits at 95% confidence level on the X-5/3 quark mass are set at 1.33 and 1.30 TeV respectively for the case of right-handed and left-handed couplings to W bosons in a combination of the same-sign dilepton and single-lepton final states.

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