Suchergebnisse

H. te Velde, Stijlen van leiderschap. Persoon en politiek van Thorbecke tot Den Uyl Jac Bosmans, The political culture between political history and the history of civilizationIn principle, the author agrees with Te Velde's choice of Thorbecke, Kuyper, Colijn, Drees and Den Uyl as examples of styles of policy-making which, with the benefit of hindsight, seem to be an apt expression of the political spirit of their days, though he does place a few question marks against the choice of Colijn and Drees. In addition, he advocates the establishment of a mutually beneficial co-operative relationship between tfiose political historians who focus in particular on investigating the cultural aspects of politics and those who are more interested in examining the actual results. He argues that this kind of co-operation is necessary in order to withstand the tendency of many cultural historians to claim almost the entire past as the focus of their research, a claim which leaves no room for political history as a separate field of study. This review is part of the discussion forum 'Stijlen van leiderschap' (H. te Velde).

Background: Effective, accessible, and affordable depression treatment is of high importance considering the large personal and economic burden of depression. Internet-based treatment is considered a promising clinical and cost-effective alternative to current routine depression treatment strategies such as face-to-face psychotherapy. However, it is not clear whether research findings translate to routine clinical practice such as primary or specialized mental health care. The E-COMPARED project aims to gain knowledge on the clinical and cost-effectiveness of blended depression treatment compared to treatment-as-usual in routine care. Methods/design: E-COMPARED will employ a pragmatic, multinational, randomized controlled, non-inferiority trial in eight European countries. Adults diagnosed with major depressive disorder (MDD) will be recruited in primary care (Germany, Poland, Spain, Sweden, and the United Kingdom) or specialized mental health care (France, The Netherlands, and Switzerland). Regular care for depression is compared to "blended" service delivery combining mobile and Internet technologies with face-to-face treatment in one treatment protocol. Participants will be followed up at 3, 6, and 12 months after baseline to determine clinical improvements in symptoms of depression (primary outcome: Patient Health Questionnaire-9), remission of depression, and cost-effectiveness. Main analyses will be conducted on the pooled data from the eight countries (n = 1200 in total, 150 participants in each country). Discussion: The E-COMPARED project will provide mental health care stakeholders with evidence-based information and recommendations on the clinical and cost-effectiveness of blended depression treatment. Trial Registration: France: ClinicalTrials.gov NCT02542891 . Registered on 4 September 2015; Germany: German Clinical Trials Register DRKS00006866 . Registered on 2 December 2014; The Netherlands: Netherlands Trials Register NTR4962 . Registered on 5 January 2015; Poland: ClinicalTrials.Gov NCT02389660 . Registered on 18 February 2015; Spain: ClinicalTrials.gov NCT02361684 . Registered on 8 January 2015; Sweden: ClinicalTrials.gov NCT02449447 . Registered on 30 March 2015; Switzerland: ClinicalTrials.gov NCT02410616 . Registered on 2 April 2015; United Kingdom: ISRCTN registry, ISRCTN12388725 . Registered on 20 March 2015. ; Funding agencies: European Commission [603098] ; E-COMPARED