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FCL and AS were supported by the Swedish Research Council (Vetenskapsrådet, grant no. 2018-01272). FCL conducted the work with this article as a Pro Futura Scientia XIII Fellow funded by the Swedish Collegium for Advanced Study through Riksbankens Jubileumsfond. WT was supported by the German Research Foundation (DFG, TE 613/3-1). AD received funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme (grant agreement no. 677152). AH was supported by Riksbankens Jubileumsfond (grant no. IN20-0026). MD-D was funded by the Dutch Research Council (Nederlandse organisatie voor Wetenschappelijk Onderzoek, grant no. 016.Veni.195.502). TK, MR, and UB were supported the SustES project – "Adaptation strategies for sustainable ecosystem services and food security under adverse environmental conditions" (CZ.02.1.01/0.0/0.0/16_019/0000797). LS was supported by Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany's Excellence Strategy – EXC 2150 ROOTS – 390870439. FL was supported by a European Research Council (ERC) Synergy Grant (4-OCEANS; grant agreement no. 951649) under the European Union's Horizon 2020 research and innovation programme. ; Although variations in building activity are a useful indicator of societal well-being and demographic development, historical datasets for larger regions and longer periods are still rare. Here, we present 54,045 annually precise dendrochronological felling dates from historical construction timber from across most of Europe between 1250 and 1699 CE to infer variations in building activity. We use geostatistical techniques to compare spatiotemporal dynamics in past European building activity against independent demographic, economic, social and climatic data. We show that the felling dates capture major geographical patterns of demographic trends, especially in regions with dense data coverage. A particularly strong negative association is found between grain prices and the number of felling dates. In addition, a significant positive association is found between the number of felling dates and mining activity. These strong associations, with well-known macro-economic indicators from pre-industrial Europe, corroborate the use of felling dates as an independent source for exploring large-scale fluctuations of societal well-being and demographic development. Three prominent examples are the building boom in the Hanseatic League region of northeastern Germany during the 13th century, the onset of the Late Medieval Crisis in much of Europe c. 1300, and the cessation of building activity in large parts of central Europe during armed conflicts such as the Thirty Years' War (1618–1648 CE). Despite new insights gained from our European-wide felling date inventory, further studies are needed to investigate changes in construction activity of high versus low status buildings, and of urban versus rural buildings, and to compare those results with a variety of historical documentary sources and natural proxy archives. ; Publisher PDF ; Peer reviewed