Suchergebnisse

In recent years, the shift to Distributed Generation (DG) and the use of smarter domestic appliances has led to an increasing integration of power electronics (active infeed converters,power drive systems etc.) at the household level. However, the use of more power electronics results in the generation of highly distorted currents entering the distribution grid. Previous research shows that such current waveforms can cause large errors in static electricity meters. Thus, there is an imperative need to study the characteristics of these current waveforms and their impact on meter readings by performing extended measurements in households. Since it is not practical to store all the high granularity waveform data of such measurements, suitable detection methods and trigger levels need to be defined to only capture the potentially problematic current waveforms. In this paper, signal processing techniques (differentiation, Short Time Fourier Transform and Wavelet Transform) are applied to current signals in order to extract features suitable for use as a trigger. Results show that the Discrete Wavelet Transform and the filter with derivative method give the most promising results and work reliably even for very noisy signals. ; This work is part of the EU joint research project "17NRM02, MeterEMI, Electromagnetic Interference on Static Electricity Meters" which has received funding from the EMPIR programme co-financed by the Participating States and from the European Union's Horizon 2020 research and innovation programme.

Abstract. The outcome of the results of some analyses of electromagnetic emissions recorded by VLF receivers at 6 kHz and 9 kHz over Agartala, Tripura, the North-Eastern state of India (Lat. 23° N, Long. 91.4° E) during the large earthquake at Muzaffarabad (Lat. 34.53° N, Long. 73.58° E) at Kashmir under Pakistan have been presented here. Spiky variations in integrated field intensity of atmospherics (IFIA) at 6 and 9 kHz have been observed 10 days prior (from midnight of 28 September 2005) to the day of occurrence of the earthquake on 8 October 2005 and the effect continued, decayed gradually and eventually ceased on 16 October 2005. The spikes distinctly superimposed on the ambient level with mutual separation of 2–5 min. Occurrence number of spikes per hour and total duration of their occurrence have been found remarkably high on the day of occurrence of the earthquake. The spike heights are higher at 6 kHz than at 9 kHz. The results have been explained on the basis of generation of electromagnetic radiation associated with fracture of rocks, their subsequent penetration into the Earth's atmosphere and finally their propagation between Earth-ionosphere waveguide. The present observation shows that VLF anomaly is well-confined between 6 and 9 kHz.

IntroductionFalls in older adults are associated with increased healthcare costs. Falls may be prevented or minimised with multifactorial interventions including exercise and behavioural modification.
Objectives and ApproachTo describe the reach of the scale-up of Stepping On, a fall prevention program targeting community-dwellers aged 65 years and older in NSW, Australia; and fall-related ambulance service use and fall-related hospitalisations after scale-up. Routinely-collected data on program reach, fall-related ambulance usage and fall-related hospital admissions in NSW residents aged ≥65 years between 2009 and 2015 were compared within Statistical Local Areas prior to and following implementation of Stepping On using multilevel models.
ResultsFrom 2009 to 2014 the program was delivered in 1,077 sites to 10,096 people with an average (SD) age of 81.0 (7.2) years. Rates of fall-related ambulance use and hospital admissions per 100-person-years were 1-2 in people aged 66-74, 4-5 in people aged 75-84 and 12-13 in people aged ≥85. These rates increased over time (p<.001). Overall, the interaction between time and program delivery was not significant for fall-related ambulance use or hospital admissions. The time-related increase in fall-related ambulance usage in people aged 75-84 years may have been moderated by Stepping On (RR 0.97, 95% CI 0.93–1.00, p=.045).
Conclusion / ImplicationsThere was no indication of either a reduced rate of fall-related ambulance use or hospital admissions across the entire sample. There was a suggestion of a reduction in ambulance call-outs for falls in people aged 75-84. The lack of a detectable impact on fall-related health service usage may be due to the use of routinely collected data not intended for research purposes or inability to remove those who would be ineligible for Stepping On from the data analyses. Increasing the program reach and targeting groups contributing most to health service utilisation may improve program outcomes.

OBJECTIVE--To assess the efficacy of a short course chemotherapy regimen for treating tuberculosis of the lymph nodes in children. DESIGN--Open, collaborative, outpatient clinical trial. SETTING--Outpatient department of the Tuberculosis Research Centre, paediatric surgery departments of the Institute of Child Health and Hospital for Children and the Government Stanley Hospital, Madras, South India. PATIENTS--Children aged 1-12 years with extensive, multiple site, superficial tuberculous lymphadenitis confirmed by biopsy (histopathology or culture). INTERVENTIONS--Patients were treated with a fully supervised intermittent chemotherapy regimen consisting of streptomycin, rifampicin, isoniazid, and pyrazinamide three times a week for two months followed by streptomycin and isoniazid twice a week for four months on an outpatient basis. Surgery was limited to biopsy of nodes for diagnosis and assessment. MAIN OUTCOME MEASURES--Response to chemotherapy was assessed by regression of lymph nodes and healing of sinuses and abscesses during treatment and follow up. Compliance with treatment and frequency of adverse reactions were also estimated. RESULTS--197 Patients were admitted to the study and 168 into the analysis. The regimen was well tolerated and compliance was good with 101 (60%) patients receiving the prescribed chemotherapy within 15 days of the stipulated period of six months. Those whose chemotherapy extended beyond that period received the same total number of doses. Clinical response was favourable in most patients at the end of treatment. Sinuses and abscesses healed rapidly. Residual lymphadenopathy (exceeding 10 mm diameter) was present in 50 (30%) patients at the end of treatment; these nodes were biopsied. Fresh nodes, increase in size of nodes, and sinuses and abscesses occurred both during treatment and follow up. After 36 months of follow up after treatment only 5 (3%) patients required retreatment for tuberculosis. CONCLUSION--Tuberculous lymphadenitis in children can be successfully treated with ...

We present first results from radio observations with the Murchison Widefield Array seeking to constrain the power spectrum of 21 cm brightness temperature fluctuations between the redshifts of 11.6 and 17.9 (113 and 75 MHz). Three hours of observations were conducted over two nights with significantly different levels of ionospheric activity. We use these data to assess the impact of systematic errors at low frequency, including the ionosphere and radio-frequency interference, on a power spectrum measurement. We find that after the 1-3 hours of integration presented here, our measurements at the Murchison Radio Observatory are not limited by RFI, even within the FM band, and that the ionosphere does not appear to affect the level of power in the modes that we expect to be sensitive to cosmology. Power spectrum detections, inconsistent with noise, due to fine spectral structure imprinted on the foregrounds by reflections in the signal-chain, occupy the spatial Fourier modes where we would otherwise be most sensitive to the cosmological signal. We are able to reduce this contamination using calibration solutions derived from autocorrelations so that we achieve an sensitivity of 10 mK⁴ on comoving scales k ≲ 0.5 h Mpc⁻¹. This represents the first upper limits on the 21 cm power spectrum fluctuations at redshifts 12 ≲ z ≲ 18 but is still limited by calibration systematics. While calibration improvements may allow us to further remove this contamination, our results emphasize that future experiments should consider carefully the existence of and their ability to calibrate out any spectral structure within the EoR window. ; This work was supported by NSF Grants AST-0457585, AST-0821321, AST-1105835, AST-1410719, AST-1410484, AST- 1411622, and AST-1440343, by the MIT School of Science, by the Marble Astrophysics Fund, and by generous donations from Jonathan Rothberg and an anonymous donor. AEW acknowledges support from the National Science Foundation Graduate Research Fellowship under Grant No. 1122374. AM acknowledges support from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation program (grant agreement No 638809 – AIDA). Support for the MWA comes from the U.S. National Science Foundation (grants AST-0457585, PHY-0835713, CAREER- 0847753, and AST-0908884), the Australian Research Council (LIEF grants LE0775621 and LE0882938), the U.S. Air Force Of- fice of Scientific Research (grant FA9550-0510247), and the Centre for All-sky Astrophysics (an Australian Research Council Centre of Excellence funded by grant CE110001020). Support is also provided by the Smithsonian Astrophysical Observatory, the Raman Research Institute, the Australian National University, and the Victoria University of Wellington (via grant MED-E1799 from the New Zealand Ministry of Economic Development and an IBM Shared University Research Grant). The Australian Federal government provides additional support via the Commonwealth Scientific and Industrial Research Organisation (CSIRO), National Collaborative Research Infrastructure Strategy, Education Investment Fund, and the Australia India Strategic Research Fund, and Astronomy Australia Limited, under contract to Curtin University.

We present first results from radio observations with the Murchison Widefield Array seeking to constrain the power spectrum of 21 cm brightness temperature fluctuations between the redshifts of 11.6 and 17.9 (113 and 75 MHz). Three hours of observations were conducted over two nights with significantly different levels of ionospheric activity. We use these data to assess the impact of systematic errors at low frequency, including the ionosphere and radio-frequency interference, on a power spectrum measurement. We find that after the 1-3 hours of integration presented here, our measurements at the Murchison Radio Observatory are not limited by RFI, even within the FM band, and that the ionosphere does not appear to affect the level of power in the modes that we expect to be sensitive to cosmology. Power spectrum detections, inconsistent with noise, due to fine spectral structure imprinted on the foregrounds by reflections in the signal-chain, occupy the spatial Fourier modes where we would otherwise be most sensitive to the cosmological signal. We are able to reduce this contamination using calibration solutions derived from autocorrelations so that we achieve an sensitivity of 10 mK⁴ on comoving scales k ≲ 0.5 h Mpc⁻¹. This represents the first upper limits on the 21 cm power spectrum fluctuations at redshifts 12 ≲ z ≲ 18 but is still limited by calibration systematics. While calibration improvements may allow us to further remove this contamination, our results emphasize that future experiments should consider carefully the existence of and their ability to calibrate out any spectral structure within the EoR window. ; This work was supported by NSF Grants AST-0457585, AST-0821321, AST-1105835, AST-1410719, AST-1410484, AST- 1411622, and AST-1440343, by the MIT School of Science, by the Marble Astrophysics Fund, and by generous donations from Jonathan Rothberg and an anonymous donor. AEW acknowledges support from the National Science Foundation Graduate Research Fellowship under Grant No. 1122374. AM acknowledges support from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation program (grant agreement No 638809 – AIDA). Support for the MWA comes from the U.S. National Science Foundation (grants AST-0457585, PHY-0835713, CAREER- 0847753, and AST-0908884), the Australian Research Council (LIEF grants LE0775621 and LE0882938), the U.S. Air Force Of- fice of Scientific Research (grant FA9550-0510247), and the Centre for All-sky Astrophysics (an Australian Research Council Centre of Excellence funded by grant CE110001020). Support is also provided by the Smithsonian Astrophysical Observatory, the Raman Research Institute, the Australian National University, and the Victoria University of Wellington (via grant MED-E1799 from the New Zealand Ministry of Economic Development and an IBM Shared University Research Grant). The Australian Federal government provides additional support via the Commonwealth Scientific and Industrial Research Organisation (CSIRO), National Collaborative Research Infrastructure Strategy, Education Investment Fund, and the Australia India Strategic Research Fund, and Astronomy Australia Limited, under contract to Curtin University.

Background: Low-risk limits recommended for alcohol consumption vary substantially across different national guidelines. To define thresholds associated with lowest risk for all-cause mortality and cardiovascular disease, we studied individual-participant data from 599 912 current drinkers without previous cardiovascular disease. Methods: We did a combined analysis of individual-participant data from three large-scale data sources in 19 high-income countries (the Emerging Risk Factors Collaboration, EPIC-CVD, and the UK Biobank). We characterised dose–response associations and calculated hazard ratios (HRs) per 100 g per week of alcohol (12·5 units per week) across 83 prospective studies, adjusting at least for study or centre, age, sex, smoking, and diabetes. To be eligible for the analysis, participants had to have information recorded about their alcohol consumption amount and status (ie, non-drinker vs current drinker), plus age, sex, history of diabetes and smoking status, at least 1 year of follow-up after baseline, and no baseline history of cardiovascular disease. The main analyses focused on current drinkers, whose baseline alcohol consumption was categorised into eight predefined groups according to the amount in grams consumed per week. We assessed alcohol consumption in relation to all-cause mortality, total cardiovascular disease, and several cardiovascular disease subtypes. We corrected HRs for estimated long-term variability in alcohol consumption using 152 640 serial alcohol assessments obtained some years apart (median interval 5·6 years [5th–95th percentile 1·04–13·5]) from 71 011 participants from 37 studies. Findings: In the 599 912 current drinkers included in the analysis, we recorded 40 310 deaths and 39 018 incident cardiovascular disease events during 5·4 million person-years of follow-up. For all-cause mortality, we recorded a positive and curvilinear association with the level of alcohol consumption, with the minimum mortality risk around or below 100 g per week. Alcohol consumption was roughly linearly associated with a higher risk of stroke (HR per 100 g per week higher consumption 1·14, 95% CI, 1·10–1·17), coronary disease excluding myocardial infarction (1·06, 1·00–1·11), heart failure (1·09, 1·03–1·15), fatal hypertensive disease (1·24, 1·15–1·33); and fatal aortic aneurysm (1·15, 1·03–1·28). By contrast, increased alcohol consumption was log-linearly associated with a lower risk of myocardial infarction (HR 0·94, 0·91–0·97). In comparison to those who reported drinking >0–≤100 g per week, those who reported drinking >100–≤200 g per week, >200–≤350 g per week, or >350 g per week had lower life expectancy at age 40 years of approximately 6 months, 1–2 years, or 4–5 years, respectively. Interpretation: In current drinkers of alcohol in high-income countries, the threshold for lowest risk of all-cause mortality was about 100 g/week. For cardiovascular disease subtypes other than myocardial infarction, there were no clear risk thresholds below which lower alcohol consumption stopped being associated with lower disease risk. These data support limits for alcohol consumption that are lower than those recommended in most current guidelines. Funding: UK Medical Research Council, British Heart Foundation, National Institute for Health Research, European Union Framework 7, and European Research Council.

BACKGROUND: Low-risk limits recommended for alcohol consumption vary substantially across different national guidelines. To define thresholds associated with lowest risk for all-cause mortality and cardiovascular disease, we studied individual-participant data from 599 912 current drinkers without previous cardiovascular disease. METHODS: We did a combined analysis of individual-participant data from three large-scale data sources in 19 high-income countries (the Emerging Risk Factors Collaboration, EPIC-CVD, and the UK Biobank). We characterised dose-response associations and calculated hazard ratios (HRs) per 100 g per week of alcohol (12·5 units per week) across 83 prospective studies, adjusting at least for study or centre, age, sex, smoking, and diabetes. To be eligible for the analysis, participants had to have information recorded about their alcohol consumption amount and status (ie, non-drinker vs current drinker), plus age, sex, history of diabetes and smoking status, at least 1 year of follow-up after baseline, and no baseline history of cardiovascular disease. The main analyses focused on current drinkers, whose baseline alcohol consumption was categorised into eight predefined groups according to the amount in grams consumed per week. We assessed alcohol consumption in relation to all-cause mortality, total cardiovascular disease, and several cardiovascular disease subtypes. We corrected HRs for estimated long-term variability in alcohol consumption using 152 640 serial alcohol assessments obtained some years apart (median interval 5·6 years [5th-95th percentile 1·04-13·5]) from 71 011 participants from 37 studies. FINDINGS: In the 599 912 current drinkers included in the analysis, we recorded 40 310 deaths and 39 018 incident cardiovascular disease events during 5·4 million person-years of follow-up. For all-cause mortality, we recorded a positive and curvilinear association with the level of alcohol consumption, with the minimum mortality risk around or below 100 g per week. Alcohol consumption was roughly linearly associated with a higher risk of stroke (HR per 100 g per week higher consumption 1·14, 95% CI, 1·10-1·17), coronary disease excluding myocardial infarction (1·06, 1·00-1·11), heart failure (1·09, 1·03-1·15), fatal hypertensive disease (1·24, 1·15-1·33); and fatal aortic aneurysm (1·15, 1·03-1·28). By contrast, increased alcohol consumption was log-linearly associated with a lower risk of myocardial infarction (HR 0·94, 0·91-0·97). In comparison to those who reported drinking >0-≤100 g per week, those who reported drinking >100-≤200 g per week, >200-≤350 g per week, or >350 g per week had lower life expectancy at age 40 years of approximately 6 months, 1-2 years, or 4-5 years, respectively. INTERPRETATION: In current drinkers of alcohol in high-income countries, the threshold for lowest risk of all-cause mortality was about 100 g/week. For cardiovascular disease subtypes other than myocardial infarction, there were no clear risk thresholds below which lower alcohol consumption stopped being associated with lower disease risk. These data support limits for alcohol consumption that are lower than those recommended in most current guidelines. FUNDING: UK Medical Research Council, British Heart Foundation, National Institute for Health Research, European Union Framework 7, and European Research Council.