Acknowledgements A full list of acknowledgments appears in the Supplementary Note 4. Co-author A.J.M.d.C. recently passed away while this work was in process. This work was performed under the auspices of the Genetic Investigation of ANthropometric Traits (GIANT) consortium. We acknowledge the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium for encouraging CHARGE studies to participate in this effort and for the contributions of CHARGE members to the analyses conducted for this research. Funding for this study was provided by the Aase and Ejner Danielsens Foundation; Academy of Finland (41071, 77299, 102318, 110413, 117787, 121584, 123885, 124243, 124282, 126925, 129378, 134309, 286284); Accare Center for Child and Adolescent Psychiatry; Action on Hearing Loss (G51); Agence Nationale de la 359 Recherche; Agency for Health Care Policy Research (HS06516); ALF/LUA research grant in Gothenburg; ALFEDIAM; ALK-Abelló A/S; Althingi; American Heart Association (13POST16500011); Amgen; Andrea and Charles Bronfman Philanthropies; Ardix Medical; Arthritis Research UK; Association Diabète Risque Vasculaire; Australian National Health and Medical Research Council (241944, 339462, 389875, 389891, 389892, 389927, 389938, 442915, 442981, 496739, 552485, 552498); Avera Institute; Bayer Diagnostics; Becton Dickinson; BHF (RG/14/5/30893); Boston Obesity Nutrition Research Center (DK46200), Bristol-Myers Squibb; British Heart Foundation (RG/10/12/28456, RG2008/08, RG2008/014, SP/04/002); Medical Research Council of Canada; Canadian Institutes for Health Research (FRCN-CCT-83028); Cancer Research UK; Cardionics; Cavadis B.V., Center for Medical Systems Biology; Center of Excellence in Genomics; CFI; CIHR; City of Kuopio; CNAMTS; Cohortes Santé TGIR; Contrat de Projets État-Région; Croatian Science Foundation (8875); Danish Agency for Science, Technology and Innovation; Danish Council for Independent Research (DFF-1333-00124, DFF-1331-00730B); County Council of Dalarna; Dalarna University; Danish Council for Strategic Research; Danish Diabetes Academy; Danish Medical Research Council; Department of Health, UK; Development Fund from the University of Tartu (SP1GVARENG); Diabetes Hilfs- und Forschungsfonds Deutschland; Diabetes UK; Diabetes Research and Wellness Foundation Fellowship; Donald W. Reynolds Foundation; Dr Robert Pfleger-Stiftung; Dutch Brain Foundation; Dutch Diabetes Research Foundation; Dutch Inter University Cardiology Institute; Dutch Kidney Foundation (E033); Dutch Ministry of Justice; the DynaHEALTH action No. 633595, Economic Structure Enhancing Fund of the Dutch Government; Else Kröner-Fresenius-Stiftung (2012_A147, P48/08//A11/08); Emil Aaltonen Foundation; Erasmus University Medical Center Rotterdam; Erasmus MC and Erasmus University Rotterdam; the Municipality of Rotterdam; Estonian Government (IUT20-60, IUT24-6); Estonian Research Roadmap through the Estonian Ministry of Education and Research (3.2.0304.11-0312); European Research Council (ERC Starting Grant and 323195:SZ-245 50371-GLUCOSEGENES-FP7-IDEAS-ERC); European Regional Development Fund; European Science Foundation (EU/QLRT-2001-01254); European Commission (018947, 018996, 201668, 223004, 230374, 279143, 284167, 305739, BBMRI-LPC-313010, HEALTH-2011.2.4.2-2-EU-MASCARA, HEALTH-2011-278913, HEALTH-2011-294713-EPLORE, HEALTH-F2-2008-201865-GEFOS, HEALTH-F2-2013-601456, HEALTH-F4-2007-201413, HEALTH-F4-2007-201550-HYPERGENES, HEALTH-F7-305507 HOMAGE, IMI/115006, LSHG-CT-2006-018947, LSHG-CT-2006-01947, LSHM-CT-2004-005272, LSHM-CT-2006-037697, LSHM-CT-2007-037273, QLG1-CT-2002-00896, QLG2-CT-2002-01254); Faculty of Biology and Medicine of Lausanne; Federal Ministry of Education and Research (01ZZ0103, 01ZZ0403, 01ZZ9603, 03IS2061A, 03ZIK012); Federal State of Mecklenburg-West Pomerania; Fédération Française de Cardiologie; Finnish Cultural Foundation; Finnish Diabetes Association; Finnish Foundation of Cardiovascular Research; Finnish Heart Association; Fondation Leducq; Food Standards Agency; Foundation for Strategic Research; French Ministry of Research; FRSQ; Genetic Association Information Network (GAIN) of the Foundation for the NIH; German Federal Ministry of Education and Research (BMBF, 01ER1206, 01ER1507); GlaxoSmithKline; Greek General Secretary of Research and Technology; Göteborg Medical Society; Health and Safety Executive; Healthcare NHS Trust; Healthway; Western Australia; Heart Foundation of Northern Sweden; Helmholtz Zentrum München—German Research Center for Environmental Health; Hjartavernd; Ingrid Thurings Foundation; INSERM; InterOmics (PB05 MIUR-CNR); INTERREG IV Oberrhein Program (A28); Interuniversity Cardiology Institute of the Netherlands (ICIN, 09.001); Italian Ministry of Health (ICS110.1/RF97.71); Italian Ministry of Economy and Finance (FaReBio di Qualità); Marianne and Marcus Wallenberg Foundation; the Ministry of Health, Welfare and Sports, the Netherlands; J.D.E. and Catherine T, MacArthur Foundation Research Networks on Successful Midlife Development and Socioeconomic Status and Health; Juho Vainio Foundation; Juvenile Diabetes Research Foundation International; KfH Stiftung Präventivmedizin e.V.; King's College London; Knut and Alice Wallenberg Foundation; Kuopio University Hospital; Kuopio, Tampere and Turku University Hospital Medical Funds (X51001); La Fondation de France; Leenaards Foundation; Lilly; LMUinnovativ; Lundberg Foundation; Magnus Bergvall Foundation; MDEIE; Medical Research Council UK (G0000934, G0601966, G0700931, MC_U106179471, MC_UU_12019/1); MEKOS Laboratories; Merck Santé; Ministry for Health, Welfare and Sports, The Netherlands; Ministry of Cultural Affairs of Mecklenburg-West Pomerania; Ministry of Economic Affairs, The Netherlands; Ministry of Education and Culture of Finland (627;2004-2011); Ministry of Education, Culture and Science, The Netherlands; Ministry of Science, Education and Sport in the Republic of Croatia (108-1080315-0302); MRC centre for Causal Analyses in Translational Epidemiology; MRC Human Genetics Unit; MRC-GlaxoSmithKline pilot programme (G0701863); MSD Stipend Diabetes; National Institute for Health Research; Netherlands Brain Foundation (F2013(1)-28); Netherlands CardioVascular Research Initiative (CVON2011-19); Netherlands Genomics Initiative (050-060-810); Netherlands Heart Foundation (2001 D 032, NHS2010B280); Netherlands Organization for Scientific Research (NWO) and Netherlands Organisation for Health Research and Development (ZonMW) (56-464-14192, 60-60600-97-118, 100-001-004, 261-98-710, 400-05-717, 480-04-004, 480-05-003, 481-08-013, 904-61-090, 904-61-193, 911-11-025, 985-10-002, Addiction-31160008, BBMRI–NL 184.021.007, GB-MaGW 452-04-314, GB-MaGW 452-06-004, GB-MaGW 480-01-006, GB-MaGW 480-07-001, GB-MW 940-38-011, Middelgroot-911-09-032, NBIC/BioAssist/RK 2008.024, Spinozapremie 175.010.2003.005, 175.010.2007.006); Neuroscience Campus Amsterdam; NHS Foundation Trust; National Institutes of Health (1RC2MH089951, 1Z01HG000024, 24152, 263MD9164, 263MD821336, 2R01LM010098, 32100-2, 32122, 32108, 5K99HL130580-02, AA07535, AA10248, AA11998, AA13320, AA13321, AA13326, AA14041, AA17688, AG13196, CA047988, DA12854, DK56350, DK063491, DK078150, DK091718, DK100383, DK078616, ES10126, HG004790, HHSN268200625226C, HHSN268200800007C, HHSN268201200036C, HHSN268201500001I, HHSN268201100046C, HHSN268201100001C, HHSN268201100002C, HHSN268201100003C, HHSN268201100004C, HHSN271201100004C, HL043851, HL45670, HL080467, HL085144, HL087660, HL054457, HL119443, HL118305, HL071981, HL034594, HL126024, HL130114, KL2TR001109, MH66206, MH081802, N01AG12100, N01HC55015, N01HC55016, N01C55018, N01HC55019, N01HC55020, N01HC55021, N01HC55022, N01HC85079, N01HC85080, N01HC85081, N01HC85082, N01HC85083, N01HC85086, N01HC95159, N01HC95160, N01HC95161, N01HC95162, N01HC95163, N01HC95164, N01HC95165, N01HC95166, N01HC95167, N01HC95168, N01HC95169, N01HG65403, N01WH22110, N02HL6‐4278, N01-HC-25195, P01CA33619, R01HD057194, R01HD057194, R01AG023629, R01CA63, R01D004215701A, R01DK075787, R01DK062370, R01DK072193, R01DK075787, R01DK089256, R01HL53353, R01HL59367, R01HL086694, R01HL087641, R01HL087652, R01HL103612, R01HL105756, R01HL117078, R01HL120393, R03 AG046389, R37CA54281, RC2AG036495, RC4AG039029, RPPG040710371, RR20649, TW008288, TW05596, U01AG009740, U01CA98758, U01CA136792, U01DK062418, U01HG004402, U01HG004802, U01HG007376, U01HL080295, UL1RR025005, UL1TR000040, UL1TR000124, UL1TR001079, 2T32HL007055-36, T32GM074905, HG002651, HL084729, N01-HC-25195, UM1CA182913); NIH, National Institute on Aging (Intramural funding, NO1-AG-1-2109); Northern Netherlands Collaboration of Provinces; Novartis Pharma; Novo Nordisk; Novo Nordisk Foundation; Nutricia Research Foundation (2016-T1); ONIVINS; Parnassia Bavo group; Pierre Fabre; Province of Groningen; Päivikki and Sakari Sohlberg Foundation; Påhlssons Foundation; Paavo Nurmi Foundation; Radboud Medical Center Nijmegen; Research Centre for Prevention and Health, the Capital Region of Denmark; the Research Institute for Diseases in the Elderly; Research into Ageing; Robert Dawson Evans Endowment of the Department of Medicine at Boston University School of Medicine and Boston Medical Center; Roche; Royal Society; Russian Foundation for Basic Research (NWO-RFBR 047.017.043); Rutgers University Cell and DNA Repository (NIMH U24 MH068457-06); Sanofi-Aventis; Scottish Government Health Directorates, Chief Scientist Office (CZD/16/6); Siemens Healthcare; Social Insurance Institution of Finland (4/26/2010); Social Ministry of the Federal State of Mecklenburg-West Pomerania; Société Francophone du 358 Diabète; State of Bavaria; Stiftelsen för Gamla Tjänarinnor; Stockholm County Council (560183, 592229); Strategic Cardiovascular and Diabetes Programmes of Karolinska Institutet and Stockholm County Council; Stroke Association; Swedish Diabetes Association; Swedish Diabetes Foundation (2013-024); Swedish Foundation for Strategic Research; Swedish Heart-Lung Foundation (20120197, 20150711); Swedish Research Council (0593, 8691, 2012-1397, 2012-1727, and 2012-2215); Swedish Society for Medical Research; Swiss Institute of Bioinformatics; Swiss National Science Foundation (3100AO-116323/1, 31003A-143914, 33CSCO-122661, 33CS30-139468, 33CS30-148401, 51RTP0_151019); Tampere Tuberculosis Foundation; Technology Foundation STW (11679); The Fonds voor Wetenschappelijk Onderzoek Vlaanderen, Ministry of the Flemish Community (G.0880.13, G.0881.13); The Great Wine Estates of the Margaret River Region of Western Australia; Timber Merchant Vilhelm Bangs Foundation; Topcon; Tore Nilsson Foundation; Torsten and Ragnar Söderberg's Foundation; United States – Israel Binational Science Foundation (Grant 2011036), Umeå University; University Hospital of Regensburg; University of Groningen; University Medical Center Groningen; University of Michigan; University of Utrecht; Uppsala Multidisciplinary Center for Advanced Computational Science (UPPMAX) (b2011036); Velux Foundation; VU University's Institute for Health and Care Research; Västra Götaland Foundation; Wellcome Trust (068545, 076113, 079895, 084723, 088869, WT064890, WT086596, WT098017, WT090532, WT098051, 098381); Wissenschaftsoffensive TMO; Yrjö Jahnsson Foundation; and Åke Wiberg Foundation. The views expressed in this manuscript are those of the authors and do not necessarily represent the views of the National Heart, Lung, and Blood Institute (NHLBI); the National Institutes of Health (NIH); or the U.S. Department of Health and Human Services. ; Peer reviewed ; Publisher PDF
Few genome-wide association studies (GWAS) account for environmental exposures, like smoking, potentially impacting the overall trait variance when investigating the genetic contribution to obesity-related traits. Here, we use GWAS data from 51,080 current smokers and 190,178 nonsmokers (87% European descent) to identify loci influencing BMI and central adiposity, measured as waist circumference and waist-to-hip ratio both adjusted for BMI. We identify 23 novel genetic loci, and 9 loci with convincing evidence of gene-smoking interaction (GxSMK) on obesity-related traits. We show consistent direction of effect for all identified loci and significance for 18 novel and for 5 interaction loci in an independent study sample. These loci highlight novel biological functions, including response to oxidative stress, addictive behaviour, and regulatory functions emphasizing the importance of accounting for environment in genetic analyses. Our results suggest that tobacco smoking may alter the genetic susceptibility to overall adiposity and body fat distribution. ; A full list of acknowledgments appears in the Supplementary Note 4. Co-author A.J.M.d.C. recently passed away while this work was in process. This work was performed under the auspices of the Genetic Investigation of ANthropometric Traits (GIANT) consortium. We acknowledge the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium for encouraging CHARGE studies to participate in this effort and for the contributions of CHARGE members to the analyses conducted for this research. Funding for this study was provided by the Aase and Ejner Danielsens Foundation; Academy of Finland (41071, 77299, 102318, 110413, 117787, 121584, 123885, 124243, 124282, 126925, 129378, 134309, 286284); Accare Center for Child and Adolescent Psychiatry; Action on Hearing Loss (G51); Agence Nationale de la 359 Recherche; Agency for Health Care Policy Research (HS06516); ALF/LUA research grant in Gothenburg; ALFEDIAM; ALK-Abelló A/S; Althingi; American Heart Association (13POST16500011); Amgen; Andrea and Charles Bronfman Philanthropies; Ardix Medical; Arthritis Research UK; Association Diabète Risque Vasculaire; Australian National Health and Medical Research Council (241944, 339462, 389875, 389891, 389892, 389927, 389938, 442915, 442981, 496739, 552485, 552498); Avera Institute; Bayer Diagnostics; Becton Dickinson; BHF (RG/14/5/30893); Boston Obesity Nutrition Research Center (DK46200), Bristol-Myers Squibb; British Heart Foundation (RG/10/12/28456, RG2008/08, RG2008/014, SP/04/002); Medical Research Council of Canada; Canadian Institutes for Health Research (FRCN-CCT-83028); Cancer Research UK; Cardionics; Cavadis B.V., Center for Medical Systems Biology; Center of Excellence in Genomics; CFI; CIHR; City of Kuopio; CNAMTS; Cohortes Santé TGIR; Contrat de Projets État-Région; Croatian Science Foundation (8875); Danish Agency for Science, Technology and Innovation; Danish Council for Independent Research (DFF-1333-00124, DFF-1331-00730B); County Council of Dalarna; Dalarna University; Danish Council for Strategic Research; Danish Diabetes Academy; Danish Medical Research Council; Department of Health, UK; Development Fund from the University of Tartu (SP1GVARENG); Diabetes Hilfs- und Forschungsfonds Deutschland; Diabetes UK; Diabetes Research and Wellness Foundation Fellowship; Donald W. Reynolds Foundation; Dr Robert Pfleger-Stiftung; Dutch Brain Foundation; Dutch Diabetes Research Foundation; Dutch Inter University Cardiology Institute; Dutch Kidney Foundation (E033); Dutch Ministry of Justice; the DynaHEALTH action No. 633595, Economic Structure Enhancing Fund of the Dutch Government; Else Kröner-Fresenius-Stiftung (2012_A147, P48/08//A11/08); Emil Aaltonen Foundation; Erasmus University Medical Center Rotterdam; Erasmus MC and Erasmus University Rotterdam; the Municipality of Rotterdam; Estonian Government (IUT20-60, IUT24-6); Estonian Research Roadmap through the Estonian Ministry of Education and Research (3.2.0304.11-0312); European Research Council (ERC Starting Grant and 323195:SZ-245 50371-GLUCOSEGENES-FP7-IDEAS-ERC); European Regional Development Fund; European Science Foundation (EU/QLRT-2001-01254); European Commission (018947, 018996, 201668, 223004, 230374, 279143, 284167, 305739, BBMRI-LPC-313010, HEALTH-2011.2.4.2-2-EU-MASCARA, HEALTH-2011-278913, HEALTH-2011-294713-EPLORE, HEALTH-F2-2008-201865-GEFOS, HEALTH-F2-2013-601456, HEALTH-F4-2007-201413, HEALTH-F4-2007-201550-HYPERGENES, HEALTH-F7-305507 HOMAGE, IMI/115006, LSHG-CT-2006-018947, LSHG-CT-2006-01947, LSHM-CT-2004-005272, LSHM-CT-2006-037697, LSHM-CT-2007-037273, QLG1-CT-2002-00896, QLG2-CT-2002-01254); Faculty of Biology and Medicine of Lausanne; Federal Ministry of Education and Research (01ZZ0103, 01ZZ0403, 01ZZ9603, 03IS2061A, 03ZIK012); Federal State of Mecklenburg-West Pomerania; Fédération Française de Cardiologie; Finnish Cultural Foundation; Finnish Diabetes Association; Finnish Foundation of Cardiovascular Research; Finnish Heart Association; Fondation Leducq; Food Standards Agency; Foundation for Strategic Research; French Ministry of Research; FRSQ; Genetic Association Information Network (GAIN) of the Foundation for the NIH; German Federal Ministry of Education and Research (BMBF, 01ER1206, 01ER1507); GlaxoSmithKline; Greek General Secretary of Research and Technology; Göteborg Medical Society; Health and Safety Executive; Healthcare NHS Trust; Healthway; Western Australia; Heart Foundation of Northern Sweden; Helmholtz Zentrum München—German Research Center for Environmental Health; Hjartavernd; Ingrid Thurings Foundation; INSERM; InterOmics (PB05 MIUR-CNR); INTERREG IV Oberrhein Program (A28); Interuniversity Cardiology Institute of the Netherlands (ICIN, 09.001); Italian Ministry of Health (ICS110.1/RF97.71); Italian Ministry of Economy and Finance (FaReBio di Qualità); Marianne and Marcus Wallenberg Foundation; the Ministry of Health, Welfare and Sports, the Netherlands; J.D.E. and Catherine T, MacArthur Foundation Research Networks on Successful Midlife Development and Socioeconomic Status and Health; Juho Vainio Foundation; Juvenile Diabetes Research Foundation International; KfH Stiftung Präventivmedizin e.V.; King's College London; Knut and Alice Wallenberg Foundation; Kuopio University Hospital; Kuopio, Tampere and Turku University Hospital Medical Funds (X51001); La Fondation de France; Leenaards Foundation; Lilly; LMUinnovativ; Lundberg Foundation; Magnus Bergvall Foundation; MDEIE; Medical Research Council UK (G0000934, G0601966, G0700931, MC_U106179471, MC_UU_12019/1); MEKOS Laboratories; Merck Santé; Ministry for Health, Welfare and Sports, The Netherlands; Ministry of Cultural Affairs of Mecklenburg-West Pomerania; Ministry of Economic Affairs, The Netherlands; Ministry of Education and Culture of Finland (627;2004-2011); Ministry of Education, Culture and Science, The Netherlands; Ministry of Science, Education and Sport in the Republic of Croatia (108-1080315-0302); MRC centre for Causal Analyses in Translational Epidemiology; MRC Human Genetics Unit; MRC-GlaxoSmithKline pilot programme (G0701863); MSD Stipend Diabetes; National Institute for Health Research; Netherlands Brain Foundation (F2013(1)-28); Netherlands CardioVascular Research Initiative (CVON2011-19); Netherlands Genomics Initiative (050-060-810); Netherlands Heart Foundation (2001 D 032, NHS2010B280); Netherlands Organization for Scientific Research (NWO) and Netherlands Organisation for Health Research and Development (ZonMW) (56-464-14192, 60-60600-97-118, 100-001-004, 261-98-710, 400-05-717, 480-04-004, 480-05-003, 481-08-013, 904-61-090, 904-61-193, 911-11-025, 985-10-002, Addiction-31160008, BBMRI–NL 184.021.007, GB-MaGW 452-04-314, GB-MaGW 452-06-004, GB-MaGW 480-01-006, GB-MaGW 480-07-001, GB-MW 940-38-011, Middelgroot-911-09-032, NBIC/BioAssist/RK 2008.024, Spinozapremie 175.010.2003.005, 175.010.2007.006); Neuroscience Campus Amsterdam; NHS Foundation Trust; National Institutes of Health (1RC2MH089951, 1Z01HG000024, 24152, 263MD9164, 263MD821336, 2R01LM010098, 32100-2, 32122, 32108, 5K99HL130580-02, AA07535, AA10248, AA11998, AA13320, AA13321, AA13326, AA14041, AA17688, AG13196, CA047988, DA12854, DK56350, DK063491, DK078150, DK091718, DK100383, DK078616, ES10126, HG004790, HHSN268200625226C, HHSN268200800007C, HHSN268201200036C, HHSN268201500001I, HHSN268201100046C, HHSN268201100001C, HHSN268201100002C, HHSN268201100003C, HHSN268201100004C, HHSN271201100004C, HL043851, HL45670, HL080467, HL085144, HL087660, HL054457, HL119443, HL118305, HL071981, HL034594, HL126024, HL130114, KL2TR001109, MH66206, MH081802, N01AG12100, N01HC55015, N01HC55016, N01C55018, N01HC55019, N01HC55020, N01HC55021, N01HC55022, N01HC85079, N01HC85080, N01HC85081, N01HC85082, N01HC85083, N01HC85086, N01HC95159, N01HC95160, N01HC95161, N01HC95162, N01HC95163, N01HC95164, N01HC95165, N01HC95166, N01HC95167, N01HC95168, N01HC95169, N01HG65403, N01WH22110, N02HL6‐4278, N01-HC-25195, P01CA33619, R01HD057194, R01HD057194, R01AG023629, R01CA63, R01D004215701A, R01DK075787, R01DK062370, R01DK072193, R01DK075787, R01DK089256, R01HL53353, R01HL59367, R01HL086694, R01HL087641, R01HL087652, R01HL103612, R01HL105756, R01HL117078, R01HL120393, R03 AG046389, R37CA54281, RC2AG036495, RC4AG039029, RPPG040710371, RR20649, TW008288, TW05596, U01AG009740, U01CA98758, U01CA136792, U01DK062418, U01HG004402, U01HG004802, U01HG007376, U01HL080295, UL1RR025005, UL1TR000040, UL1TR000124, UL1TR001079, 2T32HL007055-36, T32GM074905, HG002651, HL084729, N01-HC-25195, UM1CA182913); NIH, National Institute on Aging (Intramural funding, NO1-AG-1-2109); Northern Netherlands Collaboration of Provinces; Novartis Pharma; Novo Nordisk; Novo Nordisk Foundation; Nutricia Research Foundation (2016-T1); ONIVINS; Parnassia Bavo group; Pierre Fabre; Province of Groningen; Päivikki and Sakari Sohlberg Foundation; Påhlssons Foundation; Paavo Nurmi Foundation; Radboud Medical Center Nijmegen; Research Centre for Prevention and Health, the Capital Region of Denmark; the Research Institute for Diseases in the Elderly; Research into Ageing; Robert Dawson Evans Endowment of the Department of Medicine at Boston University School of Medicine and Boston Medical Center; Roche; Royal Society; Russian Foundation for Basic Research (NWO-RFBR 047.017.043); Rutgers University Cell and DNA Repository (NIMH U24 MH068457-06); Sanofi-Aventis; Scottish Government Health Directorates, Chief Scientist Office (CZD/16/6); Siemens Healthcare; Social Insurance Institution of Finland (4/26/2010); Social Ministry of the Federal State of Mecklenburg-West Pomerania; Société Francophone du 358 Diabète; State of Bavaria; Stiftelsen för Gamla Tjänarinnor; Stockholm County Council (560183, 592229); Strategic Cardiovascular and Diabetes Programmes of Karolinska Institutet and Stockholm County Council; Stroke Association; Swedish Diabetes Association; Swedish Diabetes Foundation (2013-024); Swedish Foundation for Strategic Research; Swedish Heart-Lung Foundation (20120197, 20150711); Swedish Research Council (0593, 8691, 2012-1397, 2012-1727, and 2012-2215); Swedish Society for Medical Research; Swiss Institute of Bioinformatics; Swiss National Science Foundation (3100AO-116323/1, 31003A-143914, 33CSCO-122661, 33CS30-139468, 33CS30-148401, 51RTP0_151019); Tampere Tuberculosis Foundation; Technology Foundation STW (11679); The Fonds voor Wetenschappelijk Onderzoek Vlaanderen, Ministry of the Flemish Community (G.0880.13, G.0881.13); The Great Wine Estates of the Margaret River Region of Western Australia; Timber Merchant Vilhelm Bangs Foundation; Topcon; Tore Nilsson Foundation; Torsten and Ragnar Söderberg's Foundation; United States – Israel Binational Science Foundation (Grant 2011036), Umeå University; University Hospital of Regensburg; University of Groningen; University Medical Center Groningen; University of Michigan; University of Utrecht; Uppsala Multidisciplinary Center for Advanced Computational Science (UPPMAX) (b2011036); Velux Foundation; VU University's Institute for Health and Care Research; Västra Götaland Foundation; Wellcome Trust (068545, 076113, 079895, 084723, 088869, WT064890, WT086596, WT098017, WT090532, WT098051, 098381); Wissenschaftsoffensive TMO; Yrjö Jahnsson Foundation; and Åke Wiberg Foundation. The views expressed in this manuscript are those of the authors and do not necessarily represent the views of the National Heart, Lung, and Blood Institute (NHLBI); the National Institutes of Health (NIH); or the U.S. Department of Health and Human Services. ; Peer Reviewed
[SEPTEMBER 1896 - MAI 1906] [Anzeigen von Aufführungen des Landschaftlichen Theaters in Linz aus dem Vergnügungsanzeiger der "Tagespost" 1896-1927] (-) [September 1896 - Mai 1906] (1 / 1996 - Mai 1906) ( - ) Einband ( - ) I. Saison 1896 - 1897 (1.) 1. Zwei glückliche Tage. 2. Der Talisman. 3. Gebildete Menschen. (3.) 4. Das Bild der Signorelli. 5. Ein Rabenvater. 6. Die schöne Helena. (4.) 7. Die Zauberflöte. 8. Martha. 9. Die Schmetterlingsschlacht. (5.) 10. Martha. 11. Die Karlsschülerin. 12. Wettrennen. (6.) 13. Der Veilchenfreffer. 14. Der letzte Brief. 15. Carmen. 16. Der Meineidbauer. (7.) 17. Ouverture zur Oper "Mignon". Cavalleria rusticana. Ein Zündhölzchen zwischen zwei Feuer. 18. Die Orientreise. 19. Der Prophet. (8.) 20. Der Fechter von Ravenna. 21. Der Doppelhofbauer. 22. Der Widerspänstigen Zähmung. (9.) 23. Lolos Vater. 24. Die Hochzeit des Figaro. 25. Die Orientreise. (10.) 26. Dilettanten-Vorstellung. Eine Tasse Thee. 27. Yelva, die russische Waise. Die schöne Galathée. 28. Die Haubenlerche. (11.) 29. Circusleute. 30. Orpheus in der Unterwelt. 31. Circusleute. 32. Liebelei. (12.) 33. Aida. 34. Liebelei. Ein Zündhölzchen zweischen zwei Feuer. 35. Der Feldprediger. (13.) 36. Ein Böhm in Amerika. 37. Die lustigen Weiber von Windsor. 38. Die goldene Eva. (14.) 39. Wilhelm Tell. 40. Heimat. 41. Ein kecker Schnabel. (15.) 42. Der ledige Hof. 43. Othello, der Mohr von Venedig. 44. Der Evangelimann. 45. Die goldene Eva. (16.) 46. Trilby. 47. Die Zauberflöte. 48. Der Evangelimann. (17.) 49. Blaubart. 50. Der Heiratsschwindler. 51. Waldmeister. (18.) 52. Dinorah, oder: Die Wallfahrt nach Ploërmel. 53. Der Hüttenbesitzer (Le Maître de forges). 54. Mamsel Angot, die Tochter der Halle. (19.) 55. Der Nazi. 56. Das grobe Hemd. 57. Der Heiratsschwindler. 58. Die Zauberin am Stein. (20.) 59. Carmen. 60. Das grobe Hemd. 61. Die officielle Frau. 62. Aschenbrödel, oder: Der gläserne Pantoffel. (21.) 63. Der Richter von Zalamea. 64. Der Bajazzo (II Pagliacci). 65. Der Herr Ministerialdirector. 66. Des Meeres und der Liebe Wellen. (22.) 67. Die Jüdin von Toldeo. 68. Künstlernamen. 69. Tata-Toto. (23.) 70. Trilby-Parodie (Tripstrilby). Ein toller Tag, oder: Ein einsamer Spatz. 71. Der Herr Expositus. 72. Bocksprünge. (24.) 73. Jägerblut. 74. 's Lieserl von Schliersee. 75. Die Wildschützen. (25.) 76. Königskinder. (26.) 77. Die Kreuzelschreiber. (26.) II. Saison 1897 - 1898 (27.) 1. Kabale und Liebe. 2. Ernani. 3. Vasantasena. (29.) 4. Mignon. 5. Mit Vergnügen. 6. Dorf und Stadt. (30.) 7. Der Carneval in Rom. 8. Gefallene Engel. 9. Margarethe (Faust). (31.) 10. Die Leibrente. 11. Hans Huckebein. 12. Heimchen am Herd. (32.) 13. Heimchen am Herd. 14. Das Käthchen von Heilbronn oder Die Feuerprobe. 15. Der Waffenschmied von Worms. (33.) 16. Heirat auf Probe. Die Chansannette. 17. Das Tschaperl. 18. Der Freischütz. (34.) 19. Die versunkene Glocke. 20. Max und Moritz. 21. Der verwunschene Prinz. Der Präsident. (35.) 22. Die kleinen Lämmer (Schäfchen) (Les petites brebis.) 23. Der Alpenkönig und der Menschenfeind. 24. Die kleinen Lämmer (Schäfchen). (Les petites brebis.) Die Zaubergeige. (36.) 25. Goldene Herzen. 26. Romeo und Julia. 27. Der G'wissenswurm. (37.) 28. Hänsel und Gretel. 29. Eine tolle Nacht. 30. Der Postillon von Lonjumeau. (38.) 31. Frou-Frou. 32. Die Entführung aus dem Serail. 33. Andrea. (39.) 34. Die Entführung aus dem Serail. 35. Die Großherzogin von Gerolstein. 36. 's Katherl. (40.) 37. Wildfeuer. 38. Die Chansonnette. 39. Der Salontiroler. (41.) 40. Der Struwelpeter. 41. Von Cesar. 42. Der Schelm vom Kahlenberg. (42.) 43. Eine tolle Nacht. 44. Der Betrogene Kadi. Flotte Bursche. (42.) 45. Königskinder. 46. Anonyme Briefe. 47. Die wilde Jagd. (44.) 48. Ihr Corporal. 49. Anonyme Briefe. 50. Renaissance. (45.) 51. Der Schlagring. 52. Der Hergottschnitzer von Ammergau. (46.) III. Saison 1898 - 1899 (47.) 1. Die Logenbrüder. 2. Ein Blitzmädel. 3. Der Königslieutenant. (49.) 4. Minna von Barnhelm oder Das Soldatenglück. 5. Ein Judas von anno neun. (50.) 6. Der Traum ein Leben. 7. Der Barbier von Sevilla. 8. Circusleute. (51.) 9. Hofgunst. 10. Mädchentraum. 11. Lohengrin. (52.) 12. Im weißen Rössl. 13. Die Räuber. 14. Im weißen Rössl. (52.) 15. Der Opernball. 16. Die Walküre. (54.) 17. König Ottokars Glück und Ende. 18. König Ottokars Glück und Ende. (55.) 19. Die Walküre. 20. Einer von der Burgmusik. 21. Das Erbe. (56.) 22. Die Walküre. 23. Die Walküre. 24. Die Regimentstochter. Die Schulreiterin. (57.) 25. Mutter Erde. 26. Die Geisha oder Die Geschichte eines japanischen Theehauses. (58.) 27. Die Geisha oder Die Geschichte eines japanischen Theehauses. 28. Der Pariser Taugenichts. (59.) 29. Der Bibliothekar. 30. Der Vogelhändler. 31. Der Raub der Sabinerinnen. (60.) 32. Die Geisha oder Die Geschichte eines japanischen Theehauses. 33. Hofgunst. (61.) 34. Doctor Wespe. 35. Die Geisha oder Die Geschichte eines japanischen Theehauses. 36. Ein deutscher Krieger. (62.) 37. Lügenmäulchen und Wahrheitsmündchen. 38. Der Troubadour (Il Trovatore). 39. Der Opernball. 40. Robinsons Eiland. (63.) 41. Pariser leben. 42. Der Vogelhändler. 43. Fuhrmann Heuschel. (64.) 44. Die Walküre. 45. Fuhrmann Heuschel. 46. Mutter Erde. (65.) 66. Die Afrikanerin. 48. Waldmeister. 49. Kosmos. (66.) 50. Die zweite Frau (The Second Mrs. Tanqueray). 51. Der Schlafwagen-Controlor. (67.) 52. Die zärtlichen Verwandten. 53. Die Geisha oder Die Geschichte eines japanischen Theehauses. (68.) 54. Die Afrikareise. 55. Die sieben Schwaben. 56. Flitterwochen. (69.) 57. Der Protzenbauer von Tegernsee. 58. 's Haberfeldtreiben. 59. Der Amerika-Seppl. (70.) 60. (Wohltätigkeits-Akademie im landschaftlichen Theater.) (71.) IV. Saison 1899 - 1900 (73.) 1. Das Heiratsnest. 2. Mauerblümchen. 3. Die lieben Kinder. (75.) 4. Mauerblümchen. 5. Die Journalisten. 6. Hans. (76.) 7. Der Troubadour. 8. Der Schlafwagen-Controlor. 9. Des Meeres und der Liebe Wellen. (77.) 10. Die Anna-Lise. 11. Die Jüdin. 12. Der lustige Krieg. (78.) 13. Faust. 14. Zaza. 15. Das vierte Gebot. (79.) 16. Zaza. 17. Undine. 18. Boccaccio. (80.) 19. Zaza. 20. Maria Stuart. (81.) 21. Tell. 22. 's Katherl. (82.) 23. Ewige Liebe. 24. Als ich wiederkam. 25. Hand und Herz. (83.) 26. Der Ring des Nibelungen. Das Rheingold. 27. Charleys Tante. (84.) 28. Hans. 29. Ungelöste Fragen. Des Löwen Erwachen. 30. Hoffmanns Erzählungen. (85.) 31. Der Ring des Nibelungen. Das Rheingold. 32. Hoffmanns Erzählungen. (86.) 33. Die Zauberflöte. 34. Der Ring der Nibelungen. Das Rheingold. (87.) 35. Der Bettelstudent. 36. Der Athlet. (88.) 37. Der kleine Zuckerbäcker. 38. Philippine Welser oder Die schöne Augsburgerin. 39. Cabale und Liebe. (89.) 40. Die Puppe. 41. Das Rheingold. (90.) 42. Die Geisha oder Die Geschichte eines japanischen Theehauses. 43. Der Wildschütz. 44. Die Puppe. (91.) 45. Linzer Vereinsbrüder. 46. Das Rheingold. 47. Philemon und Baucis. (92.) 48. Der Sohn der Wildnis. 49. Der Freischütz. 50. Das Rheingold. (93.) 51. Schneewittchen und die Zwerge. 52. Goldfische. 53. Linzer Vereinsbrüder. (94.) 54. Der Evangelimann. 55. Die Puppe. 56. Die Geisha oder Die Geschichte eines japanischen Theehauses. (95.) 57. Die Kreuzelschreiber. 58. Othello. 59. Der Athlet. (96.) 60. Urania-Theater. 61. Der Mikado oder Ein Tag in Titipu. 62. Eine Musikstunde. La Sorpresa. - La Varietà. Sinfonia Cosmopolita. Ich heirate meine Tochter. (97.) 63. Eine ruhige Partei. Mansieur Herkules. Eine Musikstunde. - La Sorpresa. - Restaurant fin de sièole. - Sinfonia Cosmopolita. - Vorführung des Kinematographen (Bernardographen). 64. Die Puppe. 65. Der Freischütz. (98.) 66. Das fünfte Rad. 67. Des Meeres und der Liebe Wellen. 68. Der kleine Zuckerbäcker. (99.) 69. Frühling. 70. O diese Schwiegermütter. 71. Großstadtluft. (100.) 72. Zwei Wappen. 73. Um Haus und Hof. 74. Als ich wiederkam. (101.) 75. Dilettanten-Vorstellung. Lebende Bilder. Ehrung Bruckners. Aus der komischen Oper. Wiener Walzer. 76. 's Lieserl von Schliersee. (102.) 77. Almenrausch und Edelweiß. 78. D' Schatzgraber. (103.) V. Saison 1900 - 1901 (105.) 1. Gretes Glück. 2. Emilia Galotti. 3. Die Badesaison. (107.) 4. Festvorstellung. Ouverture zur Oper "Euryante". Der Kaisertag in Lohndorf. 5. Der Troubadour. (108.) 6. Abschied vom Regiment. Die Bildschnitzer. 7. Renaissance. (109.) 8. Prinz Methusalem. 9. Die Dame von Maxim. (110.) 10. Die Haubenlerche. 11. Der zerstreute Herr Professor. Unter falscher Flagge. 12. Die Jugend von heute. (111.) 13. Hamlet, Prinz von Dänemark. 14. Der Wunderknabe. 15. Die Verschwörung des Fiesco zu Genua. (112.) 16. Die Bildschnitzer. Cavalleria rusticana. 17. Wienerinnen. 18. Das vierte Gebot. (113.) 19. Der Barbier von Sevilla. 20. Eva. 21. Die Fledermaus. (114.) 22. Die sittliche Forderung. Die Bildschnitzer. Abschied vom Regiment. 23. Das Heimchen am Herd. 24. Die Meistersinger von Nürnberg. (115.) 25. Die Prinzessin von Trapezunt. 26. Mutter Sorge. 27. Mutter Sorge. (116.) 28. Die Meistersinger von Nürnberg. 29. Wienerinnen. (117.) 30. Der Freischütz. 31. Der Störenfried. 32. Eine reiche Frau. (118.) 33. Der Franzl. 34. Die Brautwerbung. (119.) 35. Flachsmann als Erzieher. 36. Die Stumme von Portici. 37. Flachsmann als Erzieher. (120.) 38. Donna Diana. 39. Wohltäter der Menschheit. 40. Die Landstreicher. (121.) 41. Linzer Drahrer. 42. Don Juan. 43. Das Glück im Winkel. (122.) 44. Rosenmontag. 45. Klein Rothkäppchen. (123.) 46. Der Verschwender. 47. Die Feldermaus. (124.) 48. Onkel Bräsig. 49. Die Landstreicher. (123. [125].) 50. Die Afrikanerin. 51. Die Meistersinger von Nürnberg. (126.) 52. Flachsmann als Erzieher. 53. Donna Juanita. 54. Coralie & Cie (127.) 55. Tannhäuser und der Sängerkrieg auf der Wartburg. 56. Die Puppe. 57. Ein armes Mädel. (128.) 58. Franz Benus. 59. Gasparone. (129.) 60. Coralie & Cie. 61. Drei Paar Schuhe. (130.) 62. Josef Lanner. 63. Die versunkene Glocke. 64. Orpheus in der Unterwelt. (131.) 65. "Ein Blick in die Tiefen des Meeres" 66., 67. Urania 7./8. V. 68. Frou-Frou. (132.) 69. Renaissance. 70. Hedda Gabler. (133.) VI. Saison 1901 - 1902 (135.) 1. Die rothe Robe. 2. Die Unehrlichen. Zu Befehl, Herr Lieutenant! 3. Die Herren Söhne. (137.) 4. Ein Fallissement. 5. Der Bettelstudent. (138.) 6. Lohengrin. 7. Die berühmte Frau. 8. Die Herren Söhne. (139.) 9. Der Schmetterling. 10. Die Zwillingsschwester. 11. Leontines Ehemänner (Les Maris de Leontine.) (140.) 12. Noth kennt kein Gebot. 13. Undine. 14. Der Freischütz. (141.) 15. Zwei glückliche Tage. 16. Der Hypochonder. 17. Der Evangelimann. (142.) 18. Der letzte Kreuzer. 19. Der Troubadour. 20. Maria Stuart. (143.) 21. Figaros Hochzeit. 22. Der neue Simson. 23. Leontines Ehemänner. (144.) 24. Rübezahl. 25. Der Krampus. 26. Der Ring des Nibelungen. Siegfried. (145.) 27. Ein toller Einfall. 28. Don Carlos. Infant von Spanien. 29. Der Jourfix. (146.) 30. Orpheus in der Unterwelt. 31. "Ein "braver" Ehemann oder Drah'n ma um und drah'n ma auf". 32. Der Opernball. (147.) 33. Bruder Martin. 34. Zu Befehl, Herr Lieutenant. Zwischen zwei Feuer. Ein Stündchen auf dem Comptoir. 35. Sein Doppelgänger. (148.) 36. Der Ring des Nibelungen. Die Walküre. 37. Im Zeichen des Kreuzes. 38. Czar und Zimmermann. (149.) 39. Der Star. 40. Goldfische. 41. Das süße Mädel. (150.) 42. Cavalleria rusticana. Der Bajazzo. 43. Kean oder Genie und Leidenschaft. (151.) 44. Mignon. (152.) 45. Liselott' 46. Galeotto. (153.) 47. Das süße Mädel. 48. Am Nikolotage. (154.) 49. Die Jüdin. 50. Die Schneeflocke. Liebelei. 51. (155.) 52. Alt-Heidelberg. 53. Der fliegende Holländer. (156.) 54. Marie oder Die Regimentstochter. 55. Die Landstreicher. (157.) 56. Die drei Wünsche. 57. Fra Diavolo. (158.) 58. Hänsel und Gretel. 59. Der Ring des Nibelungen. Das Rheingold. (159.) 60. Carmen. 61. Die Großstadtluft. 62. Die drei Wünsche. (160.) 63. Der Sängerkrieg auf der Wartburg. 64. Der Kaufmann von Venedig. (161.) 65. Der lustige Kuchelbäcker oder Der Mehlspeismacher Zweckerl oder: Ein Freund in der Noth. Hedwig, die Banditenbraut. Der Dorfbarbier. (162.) 66. Große musikalische Akademie. Franz Stelzhamer. Ballet-Vorstellung. Die Zaubergeige. Der Veilchentreffer. Die Feldermaus. Die Walküre. Der Sohn der Wildnis. (163.) 67. Der kleine Lord. Mein neuer Hut. 68. Das Mädel mit Talent. (164.) 69. Der Carneval in Rom. 70. Der kleine Mann. (165.) 71. Der Waldmeister. 72. Das süße Mädel. 73. Johannisfeuer. (166.) 74. Der Feldprediger. 75. Der Obersteiger. 76. Bürgermeister Bojer. (167.) 77. Weh' dem, der lügt! 78. Die goldene Eva. 79. Die schöne Millibäuerin vom Tegernsee. (168.) 80. Der Dorfbader. (169.) 81. Wiener Humor. Ein pensionierter Amstdiener. Vierzehn Tage im Arrest. Linzer Firmlinge. 82. Die Z'widerwurz'n. (170.) 83. Nora oder Ein Puppenheim. 84. Die Schulreiterin. (171.) Oleander und Angelmunde. (uncounted.) VII. Saison 1902 - 1903 (173.) Vom landschaftl. Theater in Linz. 1902. (175.) 1. Die Nibelungen. Der gehörnte Siegfried. Siegfrieds Tod. 2. Die Nibelungen. Kriemhilds Rache. (176.) 3. Die Zwillingsschwester. 4. Der Vogelhändler. 5. Aida. (177.) 6. Das Stiftungsfest. 7. Die Hochzeit von Valeni. 8. Der Freischütz. (178.) 9. Die Schmetterlingsschlacht. 10. Krieg im Frieden. 11. Aida. (179.) 12. Die Hoffnung. 13. Alt-Heidelberg. (180.) 14. Heilmar. 15. Die Ahnfrau. (181.) 16. Der Opernball. 17. Der Probekandidat. 18. Die lustigen Weiber von Windsor. (182.) 19. Boccaccio. 20. Der Kreuzwegstürmer. (183.) 21. Der Burengeneral. 22. Mignon. 23. Im bunten Rock. (184.) 24. Stelzhamer-Feier. 25. Die drei Wünsche. 26. Das süße Mädel. (185.) 27. Im bunten Rock. 28. Martha, oder Der Markt zu Richmond. 29. Philippine Welser. (186.) 30. Madame Sans-Gêne. 31. Das Krippenspiel von der glorreichen Geburt unseres Heilands. (187.) 32. Die Geisha oder die Geschichte eines japanischen Teehauses. 33. Ein Ehrenwort. 34. Das Aschenbrödel. (188.) 35. Die Puppe. 36. Norma. 37. Es lebe das Leben. (189.) 38. Der liebe Schatz. 39. Der Trompeter von Säkkingen. 40. Der Sängerkrieg auf der Wartburg. (190.) 41. Die Logenbücher. 42. Othello. 43. Der Waldmeister. (191.) 44. Die Einquartierung. 45. Othello. 46. Hofgunst. (192.) 47. Francillon. 48. Monna Vanna. 49. Der Gottlose. (193.) 50. Zehn Mädchen und kein Mann. 51. Die Puppenfee. 52. Rigoletto. 53. Der Probepfeil. (194.) 54. Die Afrikanerin. 55. Johannisfeuer. 56. Die versunkene Glocke. 57. Familie Schneck. (195.) 58. Angot, die Tochter der Halle. 59. Der Maskenball. (196.) 60. Hutmacher und Strumpfwirker oder Die Ahnfrau im Gemeindestadel. 61. Cosi fan tutte oder Die Schule der Liebenden. 62. Das große Licht. 63. Alessandro Stradella. (197.) 64. Die Wildente. 65. Der Pfarrer von Kirchfeld. 66. Die schöne Galathée. (198.) 67. Anno neun. Feenhände. 68. Stephan Fadinger. (199.) 69. Der Erbförster. 70. Bessere Menschen. Die Tochter. Zweierlei Tuch. 71. Jugend. (200.) 72. Der arme Heinrich. (201.) VIII. Saison 1903 - 1904 (203.) Theaternachricht. (203.) 1. Der blinde Passagier. 2. Der arme Jonathan. (204.) 3. Habsburg. 4. Lutti. 5. Der Rastelbinder. (205.) 6. Margarete. (Faust.) 7. Der Postillon von Lonjumeau. (206.) 8. Egmont. 9. Der Hochtourist. (207.) 10. Die Hugenotten. 11. Nacht und Morgen. (208.) 12. Nacht und Morgen. 13. Das Ewig-Weibliche. 14. Der Rastelbinder. 15. Cavalleria rusticana. Der Bajazzo. (209.) 16. Die Jugend von heute. 17. Der Kellermeister. (210.) 18. Wiener Blut. 19. Der Verschwender. 20. Der Strom. (211.) 21. Der Meineidbauer. 22. Götterdämmerung. (212.) 23. Der Herr Gemeinderat. 24. Die weiße Dame. 25. Die Tragödie des Menschen. (213.) 26. Die Tyrannei der Tränen. 27. Barfüßchen oder Die drei Männlein im Walde. (214.) 28. Der Kaufmann von Venedig. 29. Carmen. 30. Bruder Straubinger. (215.) 31. Queretaro. 32. Festvorstellung (216.) 33. Die Fee Caprice. 34. Robert der Teufel. 35. Sodoms Ende. (217.) 38. Der polnische Jude. 36. Der zündende Funke. (218.) 37. Er und seine Schwester. 39. Boccaccio. 40. Die schöne Helena. (219.) 41. Drei Paar Schuhe. 42. Frühlingslust. 43. Heißes Blut. (220.) 44. Figaros Hochzeit. 45. Zapfenstreich. (221.) 46. Die Einquartierung (Le billet de logement). 47. Die Journalisten. (222.) 48. Unter vier Augen. Der verwunschene Prinz. 49. Der Evangelimann. (223.) 50. Die Heimat. 51. Wiener Frauen. 52. Die Notbrücke. (224.) 53. Tonietta. 54. Bruder Straubinger. 55. Monna Vanna. (225.) 56. Seine Kammerjungfer. 57. Die Jakobsleiter. 58. Der Raub der Sabinerinnen. (226.) 59. Die Landstreicher. 60. Die Freunde. (227.) 61. Die drei Wünsche. 62. Zaza. (228.) 63. Fromont jun. und Risler sen. 64. Comtesse Guckerl. 65. Servus, Brzezina oder Indien in Wien. (229.) 66. Die tote Stadt. (230.) 67. Der Damenkrieg. (231.) Frühlingsluft. (232.) Pater Jakob. (233.) IX. Saison 1904 - 1905 (235.) Die Theaterspielzeit 1904/1905 wird von der Direktion Oskar Schramm und Karl Wallner am Samstag den 24. September mit der Neuheit "Der Meister", Komödie in drei Akten von Hermann Bahr, eröffnet werden. (235.) 1. Der Meister. 2. Der Veilchenfreffer. 3. Fidelio. (236.) 4. König Ottokars Glück und Ende. 5. Rose Bernd. 6. Orpheus in der Unterwelt. (237.) 7. Tannhäuser und der Sängerkrieg auf der Wartburg. 8. Das Veilchenmädel. 9. Wilhelm Tell. (238.) 10. Familie Schimek. 11. Zar und Zimmermann. (239.) 12. Die Glocken von Corneville. 13. Traviata. (240.) 14. Die 300 Tage. 15. s' Franzerl. (241.) 16. Götz von Berlichingen. (242.) 17. In der Sommerfrisch'n. (243.) 18. Cyrano von Bergerac. (243.) 19. Götz von Berlichingen. 20. Madame Sherry. 21. Die Ehre. (244.) 22. Ariel Acosta. 23. Madame Sherry. 24. Rosenmontag. (245.) 25. Fedora. 26. Der Wildschütz. 27. Die drei Tannen. (246.) 28. Rienzi der letzte der Tribunen. 29. Der Familientag. (247.) 30. Doktor Klaus. 31. Der Zigeunerbaron. 32. Bartel Turaser. (248.) 33. Traumulus. 34. Rienzi, der letzte der Tribunen. (249.) 35. Narciß. 36. Jung-Heidelberg. 37. Hänsel und Gretel. (250.) 38. Cavalleria rusticana. Bajazzo. 39. Pater Jakob. 40. Der Schlafwagen-Kontrollor. (251.) 41. Gyges und sein Ring. 42. Die Zauberflöte. 43. Die Herren Söhne. 44. Nachtasyl. (252.) 45. Der Evangelimann. 46. Maskerade. 47. Hoffmanns Erzählungen. (253.) 48. Zwei Wappen. 49. Der selige Toupinel. 50. Carmen. (254.) 51. Der Fremdenführer. 52. Die lustigen Weiber von Windsor. (255.) 53. Im weißen Rößl. 54. Die Gigerln von Wien. 55. Hoffmanns Erzählungen. (256.) 56. Fatinitza. 57. Der Trompeter von Säkkingen. 58. Wilhelm Tell. (257.) 59. Der Bann. 60. Des Teufels Antheil. (258.) 61. Turandot. (259.) 62. Die Zerstörung Trojas. (259.) Prinz Rosenroth und Prinzessin Lilienweiß oder Die bezauberte Lilie. Feenliebe und Ritterdumm oder Die beleidigte Rebelrose. (uncounted.) Ein Lustspiel. Die Dienstboten. (260.) X. Saison 1905 - 1906 (261.) Die Theaterspielzeit 1905/1906 wird von der Direktion Oskar Schramm und Karl Wallner am Samstag den 23. September mit dem Schauspiel "Morituri" von Hermann Sudermann eröffnet werden. (261.) 1. Morituri. 2. Cyprienne. (262.) 3. Ein nasses Abenteuer. 4. Figaros Hochzeit. (263.) 5. Maria Theresia. 6. Der Generalkonsul. 7. Helden. (264.) 8. Der Waffenschmied. 9. Prinz Methusalem. 10. Marie oder die Tochter des Regiments. 11. Ein Sommernachtstraum. (265.) 12. Orpheus in der Unterwelt. 13. Der Kilometerfresser. 14. Das Wäschermädel. (266.) 15. Die Ahnfrau. 16. Margarete (Faust). 17. Wiener Blut. (267.) 18. Die Jungfrau von Orleans. 19. Bruder Straubinger. (268.) 20. Wiener Blut. 21. Klein Dorrit. 22. Nora oder: Ein Puppenheim. (269.) 23. "Pufferl." 24. Die große Leidenschaft. (270.) 15. Pufferl. 26. "Pufferl." 27. Kettenglieder. (271.) 28. Am Tage des Gerichts. 29. Hans Heiling. (272.) 30. Die Brüder von St. Bernhard. 31. Hänsel und Gretel. 32. Die Schützenliesel. (273.) 33. Der Schwur der Treue. 34. Das süße Mädel. 35. Gummiradler. (274.) 36. Ninon von Lenclos. 37. Rigoletto. (275.) 38. Die Hugenotten. 39. Der Privatdozent. 40. Die Hochzeit von Valeni. (276.) 41. Frühlingsluft. 42. Johann Philipp Palm. (277.) 43. Die dritte Eskadron. 44. Der Barbier von Sevilla. 45. Gunther der Minnesänger. (278.) 46. Romeo und Julia. 47. Der Fall Clemenceau. 48. Das verwunschene Schloß. (279.) 49. Die Brüder von St. Bernhard. 50. Die Weber. (280.) 51. Josef und seine Brüder in Egypten. 52. Das Heiratsnest. (281.) 53. Die Logenbrüder. 54. Die lustigen Weiber von Windsor. 55. Mamselle Tourbillon. (282.) 56. Die Sittennote. 57. Die neugierigen Frauen. (283.) 58. Giroflé-Girofla 59. Carmen. (284.) 60. Der Meineidbauer. 61. Moschus. (285.) 62. Der Schätzmeister. 63. Genußmenschen. Die Sirene. Satisfaktion. (286.) 64. Das Käthchen von Heilbronn oder: Die Feuerprobe. 65. Drei Erlebnisse eines englischen Detektivs. (287.) 66. Die Schützenliesel. 67. Flachsmann als Erzieher. (288.) 68. Deutsche Bauern. (289.) Jubiläums-Wohltätigkeitsfest. (289.) Rückblick auf die Opernvorstellungen von 1896 angefangen. (291.) Einband (uncounted.) Einband (uncounted.)
This is the second volume of the Advances in Global Services and Retail Management Book Series. This volume has the following parts: Part 1: Hospitality and Tourism Part 2: Marketing, E-marketing, and Consumer Behavior Part 3: Management Part 4: Human Resources Management Part 5: Retail Management Part 6: Economics Part 7: Accounting and Finance Part 8: Sustainability and Environmental Issues Part 9: Information Technology ISBN: 978-1-955833-03-5 Hospitality and Tourism Significance of VR in the spa: A spatial analysis Irini Lai Fun Tang, Schultz Zhi Bin Xu, and Eric Chan Social media marketing in rural hospitality and tourism destination research Samuel Adeyinka-Ojo and Shamsul Kamariah Abdullah All aboard! Is space tourism still a fantasy or a reality: An investigation on Turkish market Emrah Tasarer, Vahit Oguz Kiper, Orhan Batman, and Oguz Turkay Strategic consciousness and business performance relationship of open innovation strategies in food and beverage businesses Muhsin Halis, Kazim Ozan Ozer, Hasan Cinnioglu, and Zafer Camlibel The effects of COVID-19 epidemic on guided tours and alternative tour samples from Turkey Bayram Akay The effect of COVID-19 phobia on holiday intention Halil Akmese and Ali Ilgaz The effect of the usage of virtual reality in tourism education on learning motivation Sarp Tahsin Kumlu and Emrah Ozkul The impact of effective implementation of customer relationship management to the success of hotels in Afikpo North local government of Ebonyi State, Nigeria Ogboagha Callister and Managwu Lilian The influence of study travel on quality-oriented education: The case of Handan, China Wang Jingya and Alaa Nimer Abukhalifeh The impact of U.S. Cuba policies on Cuban tourism industry: Focus on the Obama and Trump Administration Jukka M. Laitamaki, Antonio Diaz Medina, and Lisandra Torres Hechavarria Determination of students' characteristics and perspectives about social entrepreneurship: A case of Anadolu University Muhammed Kavak, Ipek Itir Can, and Emre Ozan Aksoz The place of Kazakhstan tourism sector in the countries of the region in terms of transportation infrastructure Maiya Myrzabekova, Muhsin Halis, and Zafer Camlibel What are tour guides most praised for? A sharing economy perspective Derya Demirdelen-Alrawadieh and Ibrahim Cifci An examination of representations for USA in tourism brochures for Chinese market Yasong Wang An exploratory study on cognitive internship perception of tourism students Ozge Buyuk and Gulsah Akkus Are you afraid to travel during COVID-19? Gulsum Tabak, Sibel Canik, and Ebru Guneren Destination management during the health emergency: A bibliometric analysis Valentina Della Corte, Giovanna Del Gaudio, Giuliana Nevola, Enrico Di Taranto, and Simone Luongo Determination of food neophobia levels of International Mersin Citrus Festival participants Sevda Sahilli Birdir, Nurhayat Iflazoglu, and Kemal Birdir Analysis of effectiveness of industrial exposure training undertaken by students of hospitality management in star hotels G. Saravana Kumar Conceptualization of ecotourism service experiences framework from the dimensions of motivation and quality of experiences: Four realms of experience approach Jennifer Kim Lian Chan Does Coronavirus (COVID-19) transform travel and tourism to automation (robots)? M. Omar Parvez, Ali Ozturen, and Cihan Cobanoglu Efficiency of internal control systems and the effect of organizational structure and culture on internal control systems in accommodation industry Kadriye Alev Akmese and Ali Ilgaz Ethical perceptions of housekeeping department employees: A study in Izmir Province Tuba Turkmendag and Bayram Sahin Factors that prevent participation of tourists in online co-creation activities Resat Arica, Feridun Duman, and Abdulkadir Corbaci Health sector after COVID-19: Salt thermal facilities example Azize Serap Tuncer and Sinan Bulut PRISMA statement and thematic analysis framework in hospitality and tourism research Samuel Adeyinka-Ojo Evaluation of Turkish nights as a tourism product: The case of Cappadocia Meral Buyukkuru, Eda Ozgul Katlav, and Firdevs Yonet Eren Customer perceptions against COVID-19 precautionary measures of the restaurants: The case of Istanbul-Turkey Elif Kaymaz and Sevki Ulema Analysis of e-complaints regarding hotel restaurants during COVID-19 process: The case of Antalya Sevim Usta and Serkan Sengul Marketing, E-marketing, and Consumer Behavior Materialistic social consumption amidst COVID-19 pandemic: Terror management theory in the Malaysia context Seong-Yuen Toh and Siew-Wai Yuan A conceptual framework for the mediating role of the flow experience between destination brand experience and destination loyalty Ipek Kazancoglu and Taskin Dirsehan Investigating drivers influencing choice behaviour of Islamic investment products Hanudin Amin Local food festivals within the scope of destination branding Hatice Akturk and Atilla Akbaba Marketing a destination on social media: Case of three municipalities of Izmir Huseyin Ozan Altin and Ige Pirnar Perceived usefulness, ease of use, online trust and online purchase intention: Mediating role of attitude towards online purchase Muhammed Yazeed, Mohammed Aliyu Dantsoho, and Adamu Ado Abubakar Social media framework for businesses Nawel Amrouche Social media marketing the African door of return experience in Badagry-Nigeria Huseyin Arasli, Maryam Abdullahi, and Tugrul Gunay The effect of corporate social responsibility on consumer-based brand equity: A research on automobile brands Ali Koroglu and Ibrahim Avci The effect of superstitions on consumer luck, horoscope and evil eye-oriented purchasing behavior: A study in Turkey Ibrahim Avci and Salih Yildiz The evaluation of S-D orientation on service innovation and performance of airline Inci Polat and Ozlem Atalik Brand new leisure constraint: COVID-19 Guliz Coskun The impact of consumers price level perception on emotions towards supermarkets Abdulcelil Cakici and Sena Tekeli The impact of TikTok's plastic surgery content on adolescents' self-perception and purchase intention Markus Rach Accelerated modernity: What are the social media stories undergraduate students engage with? Pericles Asher Rospigliosi and Sebastian Raza-Mejia Virtual influencer as celebrity endorsers Fanny Cheung and Wing-Fai Leung Does millennial shopping orientation using augmented reality enabled mobile applications really impact product purchase intention? Anil Kumar Exposure to e-cigarette marketing and product use among highly educated adults Onur Sahin Extending the theory of planned behavior to explain intention to use online food delivery services in the context of COVID -19 pandemic Ahmed Chemseddine Bouarar, Smail Mouloudj, and Kamel Mouloudj Factors affecting investors' buying decision in real estate market in Northern Cyprus Gurkan Arslan and Karen Howells From home to the store: Combined effect of music and traffic on consumers shopping behaviour Luigi Piper, Lucrezia Maria de Cosmo, Maria Irene Prete, and Gianluigi Guido Market expansion and business growth from the perspective of resources and capabilities: The case of a micro-enterprise Jose G. Vargas-Hernandez and Omar C. Vargas-Gonzalez How learning style interacts with voice-assisted technology (VAT) in consumer task evaluation Bonnie Canziani and Sara MacSween Effect of brand credibility and innovation on customer based brand equity and overall brand equity in Turkey: An investigation of GSM operators Suphan Nasir and Ozge Guvendik Value chain for a B school in India Vimal Chandra Verma and Devashish Das Gupta Management AI as a boost for startups companies: Evidence from Italy Irene Di Bernardo, Marco Tregua, Greco Fabio, and Ruggiero Andrea The role of quality management applications for corporate reputations Ibrahim Sapaloglu and Isik Cicek Toxicity in organizations: A sample study on the perceived toxicity in Turkish academicians Mustafa Hakan Atasoy and Muhsin Halis Which resources are matter to healthcare performance? A case study on Bahrain Mahmood Asad Ali and Mohamed Sayed Abou Elseoud Case study: HereWay Inc. European expansion: A facility location problem Mikhail M. Sher, Michael T. Paz, and Donald R. (Bob) Smith In search of the effective mission statement: Structural support of the firm's culture to augment financial performance Seong-Yuen Toh Innovation labs to support tourism organization in transforming crisis into opportunities: Insight from a case study Francesco Santarsiero, Daniela Carlucci, and Giovanni Schiuma Novelty and success of healthcare service innovation: A comparison between China and the Netherlands Yu Mu, Rujun Wang and Ying Huang Public private partnership in selected countries: A comparative analysis Bekir Parlak and Abdullahi Suleiman Hashi Strategic orientation of service enterprises towards customers Korhan Arun and Saniye Yildirim Ozmutlu The effects of organizational culture on information sharing attitude Mohammadi Lanbaran Nasrin and Cicek Isik The impact of industry 4.0 strategy on the work-life balance of employees Ali Sukru Cetinkaya The mediating effect of psychological empowerment on inclusive leadership and innovative work behaviour: A research in hotels Emete Toros, Ahmet Maslakci, and Lutfi Surucu Assessment of industry 4.0 on manufacturing enterprises: Demographic perspective Ali Sukru Cetinkaya and M. Kemal Unsacar Human Resources Management Affective commitment in new hires' onboarding? The role of organizational socialization in the fashion retail industry Pui Sze Chan, Ho Ching Ching, Pui Yi Ng, and Annie Ko Do burnout perception levels of nurses working in the health sector differ according to demographic characteristics? Irfan Akkoc and Korhan Arun Examining a moderating effect of employee turnover between recruitment and selection practice and organizational performance in Maldives civil service sector Fathmath Muna, Azam S. M. Ferdous, and Ahmad Albattat Personnel relationships in the workplace Ali Sukru Cetinkaya, Shafiq Habibi, and Umut Yavuz The evolution of human resources empowerment theory: A literature review (1970–2020) Theodoros Stavrinoudis and Moschos Psimoulis Teamwork, satisfaction and mediating effect of affective, continuance and normative commitments on employee's loyalty Thalita Aparecida Costa Nicolleti, Eduardo Roque Mangini, Leonardo Aureliano-Silva, Cristiane Sales Pires, and Carolina Aparecida de Freitas Dias Perceptions of teachers in educational institutions regarding the principles of teaching professional ethics Gulsah Aki, Nejat Ira, and Hasan Arslan Influence of psychological empowerment on employee competence in Nigerian universal basic education system: The mediating role of work engagement Isah Sani, Rashidah Binti Mohammad Ibrahim, and Fazida Karim Retail Management Artificial intelligence in retailing Ibrahim Kircova, Munise Hayrun Saglam, and Sirin Gizem Kose Customer value in retailing (2000-2020): A narrative review and future research directions Rajat Gera and Ashish Pruthi Effect of social media marketing on online retail performance of Konga Nigeria LTD Abubakar Ado Adamu, Muhammed Yazeed, Mohammed Aliyu Dantsoho, Jamilu Abdulkadir, and Aliyu Audu Gemu Employment of blue-collar workers in organized retail sector: The case of Turkey Inci Kayhan-Kuzgun Saving grace: Digitization to stay or address crisis? Smitha Vasudevan Inclusion of disabled consumers in online retail landscape: Web accessibility conformance of Turkish organized food retailers' web sites Asiye Ayben Celik A customer segmentation model proposal for retailers: RFM-V Pinar Ozkan and Ipek Deveci Kocakoc Economics Nigeria's economic management: Reflections through monthly interest rate movement from 1996 to 2020 and beyond Job Nmadu, Halima Sallawu, and Yebosoko Nmadu A qualitative study of perceptions of the residents of Sidon, Lebanon regarding the economic effect on Sidon with reference to repatriation of the Palestinian refugees Raja El Majzoub and Karen Howells Three keys of development: Knowledge, efficiency and innovative entrepreneurship Irfan Kalayci, Ali Soylu, and Baris Aytekin Tourism and women empowerment: Empirical findings from past experience and predictions for the post-COVID era Burcu Turkcan COVID-19 effect on FDI motivation and their impact on service sector: Case of Georgia Vakhtang Charaia and Mariam Lashkhi Economic cooperation between Central Caucasus, China, and EU, under COVID-19 challenges Vakhtang Charaia and Mariam Lashkhi Effect of real exchange rate and income on international tourist arrivals for Turkey Erhan Aslanoglu, Oral Erdogan, and Yasin Enes Aksu Innovative entrepreneurship in Turkey: Micro and macro perspectives Irfan Kalayci, Baris Aytekin, and Ali Soylu Optimal fiscal and price stability in Germany: Autoregressive distributed lags (ARDL) cointegration relationship Ergin Akalpler and Dahiru Alhaji Birnintsabas Struggle with COVID-19 crisis within the scope of financial national security: The example of the Republic of Turkey Silacan Karakus The nexus between fiscal freedom and investment freedom: The case of E7 countries Mehmet Bolukbas To be or not to be a female entrepreneur in the Mexicali Valley Roberto Burgueno Romero and Jose David Ledezma Torrez Accounting and Finance Comparative measurement of working capital efficiency for Borsa Istanbul restaurants and hotels for the COVID-19 period and previous quarters Fatih Gunay and Gary Cokins Relationship between business confidence index and non-financial firms foreign exchange assets and liabilities: Evidence from ARDL bound approach Ilkut Elif Kandil-Goker The impact of RTGS on internal control - A comparative study between some Iraqi banks Salowan H. Al Taee and Noor A. Radhi The impact of working capital on cash management under IAS 7 framework: An examination of tourism listed companies in Indonesia and Turkey Tri Damayanti and Tuba Derya Baskan A nexus between mergers & acquisitions and financial performance of firms: A study of industrial sector of Pakistan Fiza Quareshi, Mukhtiar Ali, and Salar Hussain Decentralized approach to deep-learning based asset allocation Sarthak Sengupta, Priyanshu Priyam, and Anurika Vaish Sustainability and Environmental Issues Blockchain technology applied to the Consortium Etna DOC to avoid counterfeiting Matarazzo Agata, Edoardo Carmelo Spampinato, Sergio Arfo, Ugo Sinigaglia, Antonino Bajeli, and Salvino Benanti Eco-label certification, hotel performance and customer satisfaction: Analysis of a case study and future developments Michele Preziosi, Alessia Acampora, Roberto Merli, and Maria Claudia Lucchetti The integration of circular economy in the tourism industry: A framework for the implementation of circular hotels Martina Sgambati, Alessia Acampora, Olimpia Martucci, and Maria Claudia Lucchetti Using the theory of planned behavior to explore green food purchase intentions Katrina Anna Auza and Kamel Mouloudj Survey on purchasing methods of food products in Tarragona and Catania Matarazzo Agata, Vazzano Tommaso Alberto, and Squillaci Carmelo Information Technology Comparative analysis of tools for matching work-related skill profiles with CV data and other unstructured data Florian Beuttiker, Stefan Roth, Tobias Steinacher, and Thomas Hanne State-of-the-art next generation open innovation platforms Murielle De Roche, Monika Blaser, Patrick Hollinger, and Thomas Hanne The coverage of AIOT based functional service: Case study of Asian futuristic hotel Gege Wang, Irini Lai Fun Tang, Eric Chan, and Wai Hung Wilco Chan The effect of the blockchain technology on service companies and food retailers: An overview of the blockchain use cases and applications Gokhan Kirbac and Erkut Ergenc The regulation problem of cryptocurrencies Lamiha Ozturk and Ece Sulungur Understanding information technology acceptance by physicians: Testing technology acceptance model Anuruddha Indika Jagoda
This is the second volume of the Advances in Global Services and Retail Management Book Series. This volume has the following parts: Part 1: Hospitality and Tourism Part 2: Marketing, E-marketing, and Consumer Behavior Part 3: Management Part 4: Human Resources Management Part 5: Retail Management Part 6: Economics Part 7: Accounting and Finance Part 8: Sustainability and Environmental Issues Part 9: Information Technology ISBN: 978-1-955833-03-5 Hospitality and Tourism Significance of VR in the spa: A spatial analysis Irini Lai Fun Tang, Schultz Zhi Bin Xu, and Eric Chan Social media marketing in rural hospitality and tourism destination research Samuel Adeyinka-Ojo and Shamsul Kamariah Abdullah All aboard! Is space tourism still a fantasy or a reality: An investigation on Turkish market Emrah Tasarer, Vahit Oguz Kiper, Orhan Batman, and Oguz Turkay Strategic consciousness and business performance relationship of open innovation strategies in food and beverage businesses Muhsin Halis, Kazim Ozan Ozer, Hasan Cinnioglu, and Zafer Camlibel The effects of COVID-19 epidemic on guided tours and alternative tour samples from Turkey Bayram Akay The effect of COVID-19 phobia on holiday intention Halil Akmese and Ali Ilgaz The effect of the usage of virtual reality in tourism education on learning motivation Sarp Tahsin Kumlu and Emrah Ozkul The impact of effective implementation of customer relationship management to the success of hotels in Afikpo North local government of Ebonyi State, Nigeria Ogboagha Callister and Managwu Lilian The influence of study travel on quality-oriented education: The case of Handan, China Wang Jingya and Alaa Nimer Abukhalifeh The impact of U.S. Cuba policies on Cuban tourism industry: Focus on the Obama and Trump Administration Jukka M. Laitamaki, Antonio Diaz Medina, and Lisandra Torres Hechavarria Determination of students' characteristics and perspectives about social entrepreneurship: A case of Anadolu University Muhammed Kavak, Ipek Itir Can, and Emre Ozan Aksoz The place of Kazakhstan tourism sector in the countries of the region in terms of transportation infrastructure Maiya Myrzabekova, Muhsin Halis, and Zafer Camlibel What are tour guides most praised for? A sharing economy perspective Derya Demirdelen-Alrawadieh and Ibrahim Cifci An examination of representations for USA in tourism brochures for Chinese market Yasong Wang An exploratory study on cognitive internship perception of tourism students Ozge Buyuk and Gulsah Akkus Are you afraid to travel during COVID-19? Gulsum Tabak, Sibel Canik, and Ebru Guneren Destination management during the health emergency: A bibliometric analysis Valentina Della Corte, Giovanna Del Gaudio, Giuliana Nevola, Enrico Di Taranto, and Simone Luongo Determination of food neophobia levels of International Mersin Citrus Festival participants Sevda Sahilli Birdir, Nurhayat Iflazoglu, and Kemal Birdir Analysis of effectiveness of industrial exposure training undertaken by students of hospitality management in star hotels G. Saravana Kumar Conceptualization of ecotourism service experiences framework from the dimensions of motivation and quality of experiences: Four realms of experience approach Jennifer Kim Lian Chan Does Coronavirus (COVID-19) transform travel and tourism to automation (robots)? M. Omar Parvez, Ali Ozturen, and Cihan Cobanoglu Efficiency of internal control systems and the effect of organizational structure and culture on internal control systems in accommodation industry Kadriye Alev Akmese and Ali Ilgaz Ethical perceptions of housekeeping department employees: A study in Izmir Province Tuba Turkmendag and Bayram Sahin Factors that prevent participation of tourists in online co-creation activities Resat Arica, Feridun Duman, and Abdulkadir Corbaci Health sector after COVID-19: Salt thermal facilities example Azize Serap Tuncer and Sinan Bulut PRISMA statement and thematic analysis framework in hospitality and tourism research Samuel Adeyinka-Ojo Evaluation of Turkish nights as a tourism product: The case of Cappadocia Meral Buyukkuru, Eda Ozgul Katlav, and Firdevs Yonet Eren Customer perceptions against COVID-19 precautionary measures of the restaurants: The case of Istanbul-Turkey Elif Kaymaz and Sevki Ulema Analysis of e-complaints regarding hotel restaurants during COVID-19 process: The case of Antalya Sevim Usta and Serkan Sengul Marketing, E-marketing, and Consumer Behavior Materialistic social consumption amidst COVID-19 pandemic: Terror management theory in the Malaysia context Seong-Yuen Toh and Siew-Wai Yuan A conceptual framework for the mediating role of the flow experience between destination brand experience and destination loyalty Ipek Kazancoglu and Taskin Dirsehan Investigating drivers influencing choice behaviour of Islamic investment products Hanudin Amin Local food festivals within the scope of destination branding Hatice Akturk and Atilla Akbaba Marketing a destination on social media: Case of three municipalities of Izmir Huseyin Ozan Altin and Ige Pirnar Perceived usefulness, ease of use, online trust and online purchase intention: Mediating role of attitude towards online purchase Muhammed Yazeed, Mohammed Aliyu Dantsoho, and Adamu Ado Abubakar Social media framework for businesses Nawel Amrouche Social media marketing the African door of return experience in Badagry-Nigeria Huseyin Arasli, Maryam Abdullahi, and Tugrul Gunay The effect of corporate social responsibility on consumer-based brand equity: A research on automobile brands Ali Koroglu and Ibrahim Avci The effect of superstitions on consumer luck, horoscope and evil eye-oriented purchasing behavior: A study in Turkey Ibrahim Avci and Salih Yildiz The evaluation of S-D orientation on service innovation and performance of airline Inci Polat and Ozlem Atalik Brand new leisure constraint: COVID-19 Guliz Coskun The impact of consumers price level perception on emotions towards supermarkets Abdulcelil Cakici and Sena Tekeli The impact of TikTok's plastic surgery content on adolescents' self-perception and purchase intention Markus Rach Accelerated modernity: What are the social media stories undergraduate students engage with? Pericles Asher Rospigliosi and Sebastian Raza-Mejia Virtual influencer as celebrity endorsers Fanny Cheung and Wing-Fai Leung Does millennial shopping orientation using augmented reality enabled mobile applications really impact product purchase intention? Anil Kumar Exposure to e-cigarette marketing and product use among highly educated adults Onur Sahin Extending the theory of planned behavior to explain intention to use online food delivery services in the context of COVID -19 pandemic Ahmed Chemseddine Bouarar, Smail Mouloudj, and Kamel Mouloudj Factors affecting investors' buying decision in real estate market in Northern Cyprus Gurkan Arslan and Karen Howells From home to the store: Combined effect of music and traffic on consumers shopping behaviour Luigi Piper, Lucrezia Maria de Cosmo, Maria Irene Prete, and Gianluigi Guido Market expansion and business growth from the perspective of resources and capabilities: The case of a micro-enterprise Jose G. Vargas-Hernandez and Omar C. Vargas-Gonzalez How learning style interacts with voice-assisted technology (VAT) in consumer task evaluation Bonnie Canziani and Sara MacSween Effect of brand credibility and innovation on customer based brand equity and overall brand equity in Turkey: An investigation of GSM operators Suphan Nasir and Ozge Guvendik Value chain for a B school in India Vimal Chandra Verma and Devashish Das Gupta Management AI as a boost for startups companies: Evidence from Italy Irene Di Bernardo, Marco Tregua, Greco Fabio, and Ruggiero Andrea The role of quality management applications for corporate reputations Ibrahim Sapaloglu and Isik Cicek Toxicity in organizations: A sample study on the perceived toxicity in Turkish academicians Mustafa Hakan Atasoy and Muhsin Halis Which resources are matter to healthcare performance? A case study on Bahrain Mahmood Asad Ali and Mohamed Sayed Abou Elseoud Case study: HereWay Inc. European expansion: A facility location problem Mikhail M. Sher, Michael T. Paz, and Donald R. (Bob) Smith In search of the effective mission statement: Structural support of the firm's culture to augment financial performance Seong-Yuen Toh Innovation labs to support tourism organization in transforming crisis into opportunities: Insight from a case study Francesco Santarsiero, Daniela Carlucci, and Giovanni Schiuma Novelty and success of healthcare service innovation: A comparison between China and the Netherlands Yu Mu, Rujun Wang and Ying Huang Public private partnership in selected countries: A comparative analysis Bekir Parlak and Abdullahi Suleiman Hashi Strategic orientation of service enterprises towards customers Korhan Arun and Saniye Yildirim Ozmutlu The effects of organizational culture on information sharing attitude Mohammadi Lanbaran Nasrin and Cicek Isik The impact of industry 4.0 strategy on the work-life balance of employees Ali Sukru Cetinkaya The mediating effect of psychological empowerment on inclusive leadership and innovative work behaviour: A research in hotels Emete Toros, Ahmet Maslakci, and Lutfi Surucu Assessment of industry 4.0 on manufacturing enterprises: Demographic perspective Ali Sukru Cetinkaya and M. Kemal Unsacar Human Resources Management Affective commitment in new hires' onboarding? The role of organizational socialization in the fashion retail industry Pui Sze Chan, Ho Ching Ching, Pui Yi Ng, and Annie Ko Do burnout perception levels of nurses working in the health sector differ according to demographic characteristics? Irfan Akkoc and Korhan Arun Examining a moderating effect of employee turnover between recruitment and selection practice and organizational performance in Maldives civil service sector Fathmath Muna, Azam S. M. Ferdous, and Ahmad Albattat Personnel relationships in the workplace Ali Sukru Cetinkaya, Shafiq Habibi, and Umut Yavuz The evolution of human resources empowerment theory: A literature review (1970–2020) Theodoros Stavrinoudis and Moschos Psimoulis Teamwork, satisfaction and mediating effect of affective, continuance and normative commitments on employee's loyalty Thalita Aparecida Costa Nicolleti, Eduardo Roque Mangini, Leonardo Aureliano-Silva, Cristiane Sales Pires, and Carolina Aparecida de Freitas Dias Perceptions of teachers in educational institutions regarding the principles of teaching professional ethics Gulsah Aki, Nejat Ira, and Hasan Arslan Influence of psychological empowerment on employee competence in Nigerian universal basic education system: The mediating role of work engagement Isah Sani, Rashidah Binti Mohammad Ibrahim, and Fazida Karim Retail Management Artificial intelligence in retailing Ibrahim Kircova, Munise Hayrun Saglam, and Sirin Gizem Kose Customer value in retailing (2000-2020): A narrative review and future research directions Rajat Gera and Ashish Pruthi Effect of social media marketing on online retail performance of Konga Nigeria LTD Abubakar Ado Adamu, Muhammed Yazeed, Mohammed Aliyu Dantsoho, Jamilu Abdulkadir, and Aliyu Audu Gemu Employment of blue-collar workers in organized retail sector: The case of Turkey Inci Kayhan-Kuzgun Saving grace: Digitization to stay or address crisis? Smitha Vasudevan Inclusion of disabled consumers in online retail landscape: Web accessibility conformance of Turkish organized food retailers' web sites Asiye Ayben Celik A customer segmentation model proposal for retailers: RFM-V Pinar Ozkan and Ipek Deveci Kocakoc Economics Nigeria's economic management: Reflections through monthly interest rate movement from 1996 to 2020 and beyond Job Nmadu, Halima Sallawu, and Yebosoko Nmadu A qualitative study of perceptions of the residents of Sidon, Lebanon regarding the economic effect on Sidon with reference to repatriation of the Palestinian refugees Raja El Majzoub and Karen Howells Three keys of development: Knowledge, efficiency and innovative entrepreneurship Irfan Kalayci, Ali Soylu, and Baris Aytekin Tourism and women empowerment: Empirical findings from past experience and predictions for the post-COVID era Burcu Turkcan COVID-19 effect on FDI motivation and their impact on service sector: Case of Georgia Vakhtang Charaia and Mariam Lashkhi Economic cooperation between Central Caucasus, China, and EU, under COVID-19 challenges Vakhtang Charaia and Mariam Lashkhi Effect of real exchange rate and income on international tourist arrivals for Turkey Erhan Aslanoglu, Oral Erdogan, and Yasin Enes Aksu Innovative entrepreneurship in Turkey: Micro and macro perspectives Irfan Kalayci, Baris Aytekin, and Ali Soylu Optimal fiscal and price stability in Germany: Autoregressive distributed lags (ARDL) cointegration relationship Ergin Akalpler and Dahiru Alhaji Birnintsabas Struggle with COVID-19 crisis within the scope of financial national security: The example of the Republic of Turkey Silacan Karakus The nexus between fiscal freedom and investment freedom: The case of E7 countries Mehmet Bolukbas To be or not to be a female entrepreneur in the Mexicali Valley Roberto Burgueno Romero and Jose David Ledezma Torrez Accounting and Finance Comparative measurement of working capital efficiency for Borsa Istanbul restaurants and hotels for the COVID-19 period and previous quarters Fatih Gunay and Gary Cokins Relationship between business confidence index and non-financial firms foreign exchange assets and liabilities: Evidence from ARDL bound approach Ilkut Elif Kandil-Goker The impact of RTGS on internal control - A comparative study between some Iraqi banks Salowan H. Al Taee and Noor A. Radhi The impact of working capital on cash management under IAS 7 framework: An examination of tourism listed companies in Indonesia and Turkey Tri Damayanti and Tuba Derya Baskan A nexus between mergers & acquisitions and financial performance of firms: A study of industrial sector of Pakistan Fiza Quareshi, Mukhtiar Ali, and Salar Hussain Decentralized approach to deep-learning based asset allocation Sarthak Sengupta, Priyanshu Priyam, and Anurika Vaish Sustainability and Environmental Issues Blockchain technology applied to the Consortium Etna DOC to avoid counterfeiting Matarazzo Agata, Edoardo Carmelo Spampinato, Sergio Arfo, Ugo Sinigaglia, Antonino Bajeli, and Salvino Benanti Eco-label certification, hotel performance and customer satisfaction: Analysis of a case study and future developments Michele Preziosi, Alessia Acampora, Roberto Merli, and Maria Claudia Lucchetti The integration of circular economy in the tourism industry: A framework for the implementation of circular hotels Martina Sgambati, Alessia Acampora, Olimpia Martucci, and Maria Claudia Lucchetti Using the theory of planned behavior to explore green food purchase intentions Katrina Anna Auza and Kamel Mouloudj Survey on purchasing methods of food products in Tarragona and Catania Matarazzo Agata, Vazzano Tommaso Alberto, and Squillaci Carmelo Information Technology Comparative analysis of tools for matching work-related skill profiles with CV data and other unstructured data Florian Beuttiker, Stefan Roth, Tobias Steinacher, and Thomas Hanne State-of-the-art next generation open innovation platforms Murielle De Roche, Monika Blaser, Patrick Hollinger, and Thomas Hanne The coverage of AIOT based functional service: Case study of Asian futuristic hotel Gege Wang, Irini Lai Fun Tang, Eric Chan, and Wai Hung Wilco Chan The effect of the blockchain technology on service companies and food retailers: An overview of the blockchain use cases and applications Gokhan Kirbac and Erkut Ergenc The regulation problem of cryptocurrencies Lamiha Ozturk and Ece Sulungur Understanding information technology acceptance by physicians: Testing technology acceptance model Anuruddha Indika Jagoda
BACKGROUND: Low-risk limits recommended for alcohol consumption vary substantially across different national guidelines. To define thresholds associated with lowest risk for all-cause mortality and cardiovascular disease, we studied individual-participant data from 599 912 current drinkers without previous cardiovascular disease. METHODS: We did a combined analysis of individual-participant data from three large-scale data sources in 19 high-income countries (the Emerging Risk Factors Collaboration, EPIC-CVD, and the UK Biobank). We characterised dose-response associations and calculated hazard ratios (HRs) per 100 g per week of alcohol (12·5 units per week) across 83 prospective studies, adjusting at least for study or centre, age, sex, smoking, and diabetes. To be eligible for the analysis, participants had to have information recorded about their alcohol consumption amount and status (ie, non-drinker vs current drinker), plus age, sex, history of diabetes and smoking status, at least 1 year of follow-up after baseline, and no baseline history of cardiovascular disease. The main analyses focused on current drinkers, whose baseline alcohol consumption was categorised into eight predefined groups according to the amount in grams consumed per week. We assessed alcohol consumption in relation to all-cause mortality, total cardiovascular disease, and several cardiovascular disease subtypes. We corrected HRs for estimated long-term variability in alcohol consumption using 152 640 serial alcohol assessments obtained some years apart (median interval 5·6 years [5th-95th percentile 1·04-13·5]) from 71 011 participants from 37 studies. FINDINGS: In the 599 912 current drinkers included in the analysis, we recorded 40 310 deaths and 39 018 incident cardiovascular disease events during 5·4 million person-years of follow-up. For all-cause mortality, we recorded a positive and curvilinear association with the level of alcohol consumption, with the minimum mortality risk around or below 100 g per week. Alcohol consumption was roughly linearly associated with a higher risk of stroke (HR per 100 g per week higher consumption 1·14, 95% CI, 1·10-1·17), coronary disease excluding myocardial infarction (1·06, 1·00-1·11), heart failure (1·09, 1·03-1·15), fatal hypertensive disease (1·24, 1·15-1·33); and fatal aortic aneurysm (1·15, 1·03-1·28). By contrast, increased alcohol consumption was log-linearly associated with a lower risk of myocardial infarction (HR 0·94, 0·91-0·97). In comparison to those who reported drinking >0-≤100 g per week, those who reported drinking >100-≤200 g per week, >200-≤350 g per week, or >350 g per week had lower life expectancy at age 40 years of approximately 6 months, 1-2 years, or 4-5 years, respectively. INTERPRETATION: In current drinkers of alcohol in high-income countries, the threshold for lowest risk of all-cause mortality was about 100 g/week. For cardiovascular disease subtypes other than myocardial infarction, there were no clear risk thresholds below which lower alcohol consumption stopped being associated with lower disease risk. These data support limits for alcohol consumption that are lower than those recommended in most current guidelines. FUNDING: UK Medical Research Council, British Heart Foundation, National Institute for Health Research, European Union Framework 7, and European Research Council.
Background: In all societies, the burden and cost of allergic and chronic respiratory diseases are increasing rapidly. Most economies are struggling to deliver modern health care effectively. There is a need to support the transformation of the health care system into integrated care with organizational health literacy. Main body: As an example for chronic disease care, MASK (Mobile Airways Sentinel NetworK), a new project of the ARIA (Allergic Rhinitis and its Impact on Asthma) initiative, and POLLAR (Impact of Air POLLution on Asthma and Rhinitis, EIT Health), in collaboration with professional and patient organizations in the field of allergy and airway diseases, are proposing real-life ICPs centred around the patient with rhinitis, and using mHealth to monitor environmental exposure. Three aspects of care pathways are being developed: (i) Patient participation, health literacy and self-care through technology-assisted "patient activation", (ii) Implementation of care pathways by pharmacists and (iii) Next-generation guidelines assessing the recommendations of GRADE guidelines in rhinitis and asthma using real-world evidence (RWE) obtained through mobile technology. The EU and global political agendas are of great importance in supporting the digital transformation of health and care, and MASK has been recognized by DG Sante as a Good Practice in the field of digitally-enabled, integrated, person-centred care. Conclusion: In 20 years, ARIA has considerably evolved from the first multimorbidity guideline in respiratory diseases to the digital transformation of health and care with a strong political involvement.
Background In all societies, the burden and cost of allergic and chronic respiratory diseases are increasing rapidly. Most economies are struggling to deliver modern health care effectively. There is a need to support the transformation of the health care system into integrated care with organizational health literacy. Main body As an example for chronic disease care, MASK (Mobile Airways Sentinel NetworK), a new project of the ARIA (Allergic Rhinitis and its Impact on Asthma) initiative, and POLLAR (Impact of Air POLLution on Asthma and Rhinitis, EIT Health), in collaboration with professional and patient organizations in the field of allergy and airway diseases, are proposing real-life ICPs centred around the patient with rhinitis, and using mHealth to monitor environmental exposure. Three aspects of care pathways are being developed: (i) Patient participation, health literacy and self-care through technology-assisted "patient activation", (ii) Implementation of care pathways by pharmacists and (iii) Next-generation guidelines assessing the recommendations of GRADE guidelines in rhinitis and asthma using real-world evidence (RWE) obtained through mobile technology. The EU and global political agendas are of great importance in supporting the digital transformation of health and care, and MASK has been recognized by DG Santé as a Good Practice in the field of digitally-enabled, integrated, person-centred care. Conclusion In 20 years, ARIA has considerably evolved from the first multimorbidity guideline in respiratory diseases to the digital transformation of health and care with a strong political involvement.
Abstract Background In all societies, the burden and cost of allergic and chronic respiratory diseases are increasing rapidly. Most economies are struggling to deliver modern health care effectively. There is a need to support the transformation of the health care system into integrated care with organizational health literacy. Main body As an example for chronic disease care, MASK (Mobile Airways Sentinel NetworK), a new project of the ARIA (Allergic Rhinitis and its Impact on Asthma) initiative, and POLLAR (Impact of Air POLLution on Asthma and Rhinitis, EIT Health), in collaboration with professional and patient organizations in the field of allergy and airway diseases, are proposing real-life ICPs centred around the patient with rhinitis, and using mHealth to monitor environmental exposure. Three aspects of care pathways are being developed: (i) Patient participation, health literacy and self-care through technology-assisted "patient activation", (ii) Implementation of care pathways by pharmacists and (iii) Next-generation guidelines assessing the recommendations of GRADE guidelines in rhinitis and asthma using real-world evidence (RWE) obtained through mobile technology. The EU and global political agendas are of great importance in supporting the digital transformation of health and care, and MASK has been recognized by DG Santé as a Good Practice in the field of digitally-enabled, integrated, person-centred care. Conclusion In 20 years, ARIA has considerably evolved from the first multimorbidity guideline in respiratory diseases to the digital transformation of health and care with a strong political involvement.
The COVIDiSTRESS global survey collects data on early human responses to the 2020 COVID-19 pandemic from 173 429 respondents in 48 countries. The open science study was co-designed by an international consortium of researchers to investigate how psychological responses differ across countries and cultures, and how this has impacted behaviour, coping and trust in government efforts to slow the spread of the virus. Starting in March 2020, COVIDiSTRESS leveraged the convenience of unpaid online recruitment to generate public data. The objective of the present analysis is to understand relationships between psychological responses in the early months of global coronavirus restrictions and help understand how different government measures succeed or fail in changing public behaviour. There were variations between and within countries. Although Western Europeans registered as more concerned over COVID-19, more stressed, and having slightly more trust in the governments' efforts, there was no clear geographical pattern in compliance with behavioural measures. Detailed plots illustrating between-countries differences are provided. Using both traditional and Bayesian analyses, we found that individuals who worried about getting sick worked harder to protect themselves and others. However, concern about the coronavirus itself did not account for all of the variances in experienced stress during the early months of COVID-19 restrictions. More alarmingly, such stress was associated with less compliance. Further, those most concerned over the coronavirus trusted in government measures primarily where policies were strict. While concern over a disease is a source of mental distress, other factors including strictness of protective measures, social support and personal lockdown conditions must also be taken into consideration to fully appreciate the psychological impact of COVID-19 and to understand why some people fail to follow behavioural guidelines intended to protect themselves and others from infection. The Stage 1 manuscript associated with this submission received in-principle acceptance (IPA) on 18 May 2020. Following IPA, the accepted Stage 1 version of the manuscript was preregistered on the Open Science Framework at https://osf.io/g2t3b. This preregistration was performed prior to data analysis. ; Peer reviewed
High-resolution estimates of HIV burden across space and time provide an important tool for tracking and monitoring the progress of prevention and control efforts and assist with improving the precision and efficiency of targeting efforts. We aimed to assess HIV incidence and HIV mortality for all second-level administrative units across sub-Saharan Africa. ; his work was primarily supported by the Bill & Melinda Gates Foundation (grant OPP1132415). Additionally, O Adetokunboh acknowledges the support of the Department of Science and Innovation, and National Research Foundation of South Africa. M Ausloos, A Pana, and C Herteliu are partially supported by a grant of the Romanian National Authority for Scientific Research and Innovation, Executive Agency for Higher Education, Research, Development and Innovation Funding (Romania; project number PN-III-P4-ID-PCCF-2016-0084). T W Bärnighausen was supported by the Alexander von Humboldt Foundation through the Alexander von Humboldt Professor award, funded by the German Federal Ministry of Education and Research. M J Bockarie is supported by the European and Developing Countries Clinical Trials Partnership. F Carvalho and E Fernandes acknowledge support from Portuguese national funds (Fundação para a Ciência e Tecnologia and Ministério da Ciência, Tecnologia e Ensino Superior; UIDB/50006/2020, UIDB/04378/2020, and UIDP/04378/2020. K Deribe is supported by the Wellcome Trust (grant 201900/Z/16/Z) as part of his International Intermediate Fellowship. B-F Hwang was partially supported by China Medical University (CMU107-Z-04), Taichung, Taiwan. M Jakovljevic acknowledges support of the Serbia Ministry of Education Science and Technological Development (grant OI 175 014). M N Khan acknowledges the support of Jatiya Kabi Kazi Nazrul Islam University, Bangladesh. Y J Kim was supported by the Research Management Centre, Xiamen University Malaysia, Malaysia, (XMUMRF/2020-C6/ITCM/0004). K Krishnan is supported by University Grants Commission Centre of Advanced Study, (CAS II), awarded to the Department of Anthropology, Panjab University, Chandigarh, India. M Kumar would like to acknowledge National Institutes of Health and Fogarty International Cente (K43TW010716). I Landires is a member of the Sistema Nacional de Investigación, which is supported by the Secretaría Nacional de Ciencia, Tecnología e Innovación, Panama. W Mendoza is a program analyst in population and development at the UN Population Fund Country Office in Peru, which does not necessarily endorse this study. M Phetole received institutional support from the Grants, Innovation and Product Development Unit, South African Medical Research Council. O Odukoya acknowledges support from the Fogarty International Center of the US National Institutes of Health (K43TW010704). The content is solely the responsibility of the authors and does not necessarily represent the official views of the US National Institutes of Health. O Oladimeji is grateful for the support from Walter Sisulu University, Eastern Cape, South Africa, the University of Botswana, Botswana, and the University of Technology of Durban, Durban, South Africa. J R Padubidri acknowledges support from Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, India. G C Patton is supported by an Australian Government National Health and Medical Research Council research fellowship. P Rathi acknowledges Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal India. A I Ribeiro was supported by National Funds through Fundação para a Ciência e Tecnologia, under the programme of Stimulus of Scientific Employment–Individual Support (CEECIND/02386/2018). A M Samy acknowledges the support of the Egyptian Fulbright Mission Program. F Sha was supported by the Shenzhen Social Science Fund (SZ2020C015) and the Shenzhen Science and Technology Program (KQTD20190929172835662). A Sheikh is supported by Health Data Research UK. N Taveira acknowledges partial funding by Fundação para a Ciência e Tecnologia, Portugal, and Aga Khan Development Network—Portugal Collaborative Research Network in Portuguese-speaking countries in Africa (332821690), and by the European and Developing Countries Clinical Trials Partnership (RIA2016MC-1615). C S Wiysonge is supported by the South African Medical Research Council. Y Zhang was supported by the Science and Technology Research Project of Hubei Provincial Department of Education (Q20201104) and Open Fund Project of Hubei Province Key Laboratory of Occupational Hazard Identification and Control (OHIC2020Y01).Editorial note: the Lancet Group takes a neutral position with respect to territorial claims in published maps and institutional affiliations
High-resolution estimates of HIV burden across space and time provide an important tool for tracking and monitoring the progress of prevention and control efforts and assist with improving the precision and efficiency of targeting efforts. We aimed to assess HIV incidence and HIV mortality for all second-level administrative units across sub-Saharan Africa. ; his work was primarily supported by the Bill & Melinda Gates Foundation (grant OPP1132415). Additionally, O Adetokunboh acknowledges the support of the Department of Science and Innovation, and National Research Foundation of South Africa. M Ausloos, A Pana, and C Herteliu are partially supported by a grant of the Romanian National Authority for Scientific Research and Innovation, Executive Agency for Higher Education, Research, Development and Innovation Funding (Romania; project number PN-III-P4-ID-PCCF-2016-0084). T W Bärnighausen was supported by the Alexander von Humboldt Foundation through the Alexander von Humboldt Professor award, funded by the German Federal Ministry of Education and Research. M J Bockarie is supported by the European and Developing Countries Clinical Trials Partnership. F Carvalho and E Fernandes acknowledge support from Portuguese national funds (Fundação para a Ciência e Tecnologia and Ministério da Ciência, Tecnologia e Ensino Superior; UIDB/50006/2020, UIDB/04378/2020, and UIDP/04378/2020. K Deribe is supported by the Wellcome Trust (grant 201900/Z/16/Z) as part of his International Intermediate Fellowship. B-F Hwang was partially supported by China Medical University (CMU107-Z-04), Taichung, Taiwan. M Jakovljevic acknowledges support of the Serbia Ministry of Education Science and Technological Development (grant OI 175 014). M N Khan acknowledges the support of Jatiya Kabi Kazi Nazrul Islam University, Bangladesh. Y J Kim was supported by the Research Management Centre, Xiamen University Malaysia, Malaysia, (XMUMRF/2020-C6/ITCM/0004). K Krishnan is supported by University Grants Commission Centre of Advanced Study, (CAS II), awarded to the Department of Anthropology, Panjab University, Chandigarh, India. M Kumar would like to acknowledge National Institutes of Health and Fogarty International Cente (K43TW010716). I Landires is a member of the Sistema Nacional de Investigación, which is supported by the Secretaría Nacional de Ciencia, Tecnología e Innovación, Panama. W Mendoza is a program analyst in population and development at the UN Population Fund Country Office in Peru, which does not necessarily endorse this study. M Phetole received institutional support from the Grants, Innovation and Product Development Unit, South African Medical Research Council. O Odukoya acknowledges support from the Fogarty International Center of the US National Institutes of Health (K43TW010704). The content is solely the responsibility of the authors and does not necessarily represent the official views of the US National Institutes of Health. O Oladimeji is grateful for the support from Walter Sisulu University, Eastern Cape, South Africa, the University of Botswana, Botswana, and the University of Technology of Durban, Durban, South Africa. J R Padubidri acknowledges support from Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, India. G C Patton is supported by an Australian Government National Health and Medical Research Council research fellowship. P Rathi acknowledges Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal India. A I Ribeiro was supported by National Funds through Fundação para a Ciência e Tecnologia, under the programme of Stimulus of Scientific Employment–Individual Support (CEECIND/02386/2018). A M Samy acknowledges the support of the Egyptian Fulbright Mission Program. F Sha was supported by the Shenzhen Social Science Fund (SZ2020C015) and the Shenzhen Science and Technology Program (KQTD20190929172835662). A Sheikh is supported by Health Data Research UK. N Taveira acknowledges partial funding by Fundação para a Ciência e Tecnologia, Portugal, and Aga Khan Development Network—Portugal Collaborative Research Network in Portuguese-speaking countries in Africa (332821690), and by the European and Developing Countries Clinical Trials Partnership (RIA2016MC-1615). C S Wiysonge is supported by the South African Medical Research Council. Y Zhang was supported by the Science and Technology Research Project of Hubei Provincial Department of Education (Q20201104) and Open Fund Project of Hubei Province Key Laboratory of Occupational Hazard Identification and Control (OHIC2020Y01).Editorial note: the Lancet Group takes a neutral position with respect to territorial claims in published maps and institutional affiliations
BACKGROUND: Comprehensive and comparable estimates of health spending in each country are a key input for health policy and planning, and are necessary to support the achievement of national and international health goals. Previous studies have tracked past and projected future health spending until 2040 and shown that, with economic development, countries tend to spend more on health per capita, with a decreasing share of spending from development assistance and out-of-pocket sources. We aimed to characterise the past, present, and predicted future of global health spending, with an emphasis on equity in spending across countries. METHODS: We estimated domestic health spending for 195 countries and territories from 1995 to 2016, split into three categories-government, out-of-pocket, and prepaid private health spending-and estimated development assistance for health (DAH) from 1990 to 2018. We estimated future scenarios of health spending using an ensemble of linear mixed-effects models with time series specifications to project domestic health spending from 2017 through 2050 and DAH from 2019 through 2050. Data were extracted from a broad set of sources tracking health spending and revenue, and were standardised and converted to inflation-adjusted 2018 US dollars. Incomplete or low-quality data were modelled and uncertainty was estimated, leading to a complete data series of total, government, prepaid private, and out-of-pocket health spending, and DAH. Estimates are reported in 2018 US dollars, 2018 purchasing-power parity-adjusted dollars, and as a percentage of gross domestic product. We used demographic decomposition methods to assess a set of factors associated with changes in government health spending between 1995 and 2016 and to examine evidence to support the theory of the health financing transition. We projected two alternative future scenarios based on higher government health spending to assess the potential ability of governments to generate more resources for health. FINDINGS: Between 1995 and 2016, health spending grew at a rate of 4·00% (95% uncertainty interval 3·89-4·12) annually, although it grew slower in per capita terms (2·72% [2·61-2·84]) and increased by less than $1 per capita over this period in 22 of 195 countries. The highest annual growth rates in per capita health spending were observed in upper-middle-income countries (5·55% [5·18-5·95]), mainly due to growth in government health spending, and in lower-middle-income countries (3·71% [3·10-4·34]), mainly from DAH. Health spending globally reached $8·0 trillion (7·8-8·1) in 2016 (comprising 8·6% [8·4-8·7] of the global economy and $10·3 trillion [10·1-10·6] in purchasing-power parity-adjusted dollars), with a per capita spending of US$5252 (5184-5319) in high-income countries, $491 (461-524) in upper-middle-income countries, $81 (74-89) in lower-middle-income countries, and $40 (38-43) in low-income countries. In 2016, 0·4% (0·3-0·4) of health spending globally was in low-income countries, despite these countries comprising 10·0% of the global population. In 2018, the largest proportion of DAH targeted HIV/AIDS ($9·5 billion, 24·3% of total DAH), although spending on other infectious diseases (excluding tuberculosis and malaria) grew fastest from 2010 to 2018 (6·27% per year). The leading sources of DAH were the USA and private philanthropy (excluding corporate donations and the Bill & Melinda Gates Foundation). For the first time, we included estimates of China's contribution to DAH ($644·7 million in 2018). Globally, health spending is projected to increase to $15·0 trillion (14·0-16·0) by 2050 (reaching 9·4% [7·6-11·3] of the global economy and $21·3 trillion [19·8-23·1] in purchasing-power parity-adjusted dollars), but at a lower growth rate of 1·84% (1·68-2·02) annually, and with continuing disparities in spending between countries. In 2050, we estimate that 0·6% (0·6-0·7) of health spending will occur in currently low-income countries, despite these countries comprising an estimated 15·7% of the global population by 2050. The ratio between per capita health spending in high-income and low-income countries was 130·2 (122·9-136·9) in 2016 and is projected to remain at similar levels in 2050 (125·9 [113·7-138·1]). The decomposition analysis identified governments' increased prioritisation of the health sector and economic development as the strongest factors associated with increases in government health spending globally. Future government health spending scenarios suggest that, with greater prioritisation of the health sector and increased government spending, health spending per capita could more than double, with greater impacts in countries that currently have the lowest levels of government health spending. INTERPRETATION: Financing for global health has increased steadily over the past two decades and is projected to continue increasing in the future, although at a slower pace of growth and with persistent disparities in per-capita health spending between countries. Out-of-pocket spending is projected to remain substantial outside of high-income countries. Many low-income countries are expected to remain dependent on development assistance, although with greater government spending, larger investments in health are feasible. In the absence of sustained new investments in health, increasing efficiency in health spending is essential to meet global health targets. FUNDING: Bill & Melinda Gates Foundation. ; Bill & Melinda Gates Foundation ; Sí
We introduce the AusTraits database - a compilation of values of plant traits for taxa in the Australian flora (hereafter AusTraits). AusTraits synthesises data on 448 traits across 28,640 taxa from field campaigns, published literature, taxonomic monographs, and individual taxon descriptions. Traits vary in scope from physiological measures of performance (e.g. photosynthetic gas exchange, water-use efficiency) to morphological attributes (e.g. leaf area, seed mass, plant height) which link to aspects of ecological variation. AusTraits contains curated and harmonised individual- and species-level measurements coupled to, where available, contextual information on site properties and experimental conditions. This article provides information on version 3.0.2 of AusTraits which contains data for 997,808 trait-by-taxon combinations. We envision AusTraits as an ongoing collaborative initiative for easily archiving and sharing trait data, which also provides a template for other national or regional initiatives globally to fill persistent gaps in trait knowledge. ; Funding Agencies|Australian Research CouncilAustralian Research Council [FT160100113, DE170100208, FT100100910]; National Collaborative Research Infrastructure Strategy (NCRIS)Australian GovernmentDepartment of Industry, Innovation and Science