Suchergebnisse

The aim of this paper is to present our strategy and vision to upgrade the existing ERATOSTHENES Research Centre (ERC), established within Cyprus University of Technology (CUT), into a sustainable, viable and autonomous Centre of Excellence (CoE) for Earth Surveillance and Space-Based Monitoring of the Environment (EXCELSIOR), which will provide the highest quality of related services both on the National, European and International levels. The 'EXCELSIOR' project is a Horizon 2020 Teaming project, addressing the reduction of substantial disparities in the European Union by supporting research and innovation activities and systems in low performing countries. It also aims at establishing long-term and strategic partnerships between the Teaming partners, thus reducing internal research and innovation disparities within European Research and Innovation landscape. The ERCis already an established player in the local community and has excellent active collaboration with actors from various sectors in (a) the government, (b) industry, (c) local organisations, and (d) society. In order to further engage users and citizens and to become more attractive to international research and education community, the Centre aims to be fully involved in strategic positioning on the national level, but also in Europe, the Middle East region and internationally. Some examples of how space technologies are integrated with other tools or techniques such as UAV, field spectroscopy, micro-sensors, EO space/in-situ sensors etc. for the systematic monitoring of the environment is shown. Indeed such examples fulfills the objectives of the COPERNICUS academy network (in which ERC is a member) for empowering the next generation of researchers, scientists, and entrepreneurs with suitable skill sets to use Copernicus data and information services to their full potential. Finally, opportunities for future collaboration and investments with the ERC in the Eastern Mediterranean Region are stated. Five partners have united to upgrade the existing ...

Background: There are few studies on HIV subtypes and primary and secondary antiretroviral drug resistance (ADR) in community-recruited samples in Brazil. We analyzed HIV clade diversity and prevalence of mutations associated with ADR in men who have sex with men in all five regions of Brazil.Methods: Using respondent-driven sampling, we recruited 3515 men who have sex with men in nine cities: 299 (9.5%) were HIV-positive; 143 subjects had adequate genotyping and epidemiologic data. Forty-four (30.8%) subjects were antiretroviral therapy-experienced (AE) and 99 (69.2%) antiretroviral therapy-naive (AN). We sequenced the reverse transcriptase and protease regions of the virus and analyzed them for drug resistant mutations using World Health Organization guidelines.Results: the most common subtypes were B (81.8%), C (7.7%), and recombinant forms (6.9%). the overall prevalence of primary ADR resistance was 21.4% (i.e. among the AN) and secondary ADR was 35.8% (i.e. among the AE). the prevalence of resistance to protease inhibitors was 3.9% (AN) and 4.4% (AE); to nucleoside reverse transcriptase inhibitors 15.0% (AN) and 31.0% (AE) and to nonnucleoside reverse transcriptase inhibitors 5.5% (AN) and 13.2% (AE). the most common resistance mutation for nucleoside reverse transcriptase inhibitors was 184V (17 cases) and for nonnucleoside reverse transcriptase inhibitors 103N (16 cases).Conclusions: Our data suggest a high level of both primary and secondary ADR in men who have sex with men in Brazil. Additional studies are needed to identify the correlates and causes of antiretroviral therapy resistance to limit the development of resistance among those in care and the transmission of resistant strains in the wider epidemic. ; Ministry of Health/Secretariat of Health Surveillance/Department of STD, AIDS and Viral Hepatitis through Brazilian Government ; Ministry of Health/Secretariat of Health Surveillance/Department of STD, AIDS and Viral Hepatitis through United Nations Office on Drugs and Crime-UNODC ; Department of STD, AIDS and Viral Hepatitis of the Ministry of Health ; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) ; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) ; Univ Fed Ceara, Dept Saude Comunitaria, BR-60430971 Fortaleza, Ceara, Brazil ; Universidade Federal de São Paulo, São Paulo, Brazil ; Tulane Univ, Sch Publ Hlth & Trop Med, New Orleans, LA USA ; Univ Fed Minas Gerais, Belo Horizonte, MG, Brazil ; Univ Fed Bahia, Inst Saude Colet, BR-41170290 Salvador, BA, Brazil ; Univ Fed Rio de Janeiro, Rio de Janeiro, Brazil ; Univ Brasilia, BR-70910900 Brasilia, DF, Brazil ; Univ Calif San Francisco, San Francisco, CA 94143 USA ; Univ São Paulo, LIM 03, São Paulo, Brazil ; Universidade Federal de São Paulo, São Paulo, Brazil ; Ministry of Health/Secretariat of Health Surveillance/Department of STD, AIDS and Viral Hepatitis through Brazilian Government: AD/BRA/03/H34 ; Ministry of Health/Secretariat of Health Surveillance/Department of STD, AIDS and Viral Hepatitis through United Nations Office on Drugs and Crime-UNODC: AD/BRA/03/H34 ; Department of STD, AIDS and Viral Hepatitis of the Ministry of Health: CSV 234/07 ; FAPESP: 2004/15856-9 ; CAPES: BEX 3495/06-0 ; Web of Science

AbstractWhile there has been an abundance of studies on the important relationship between physical activity and age in both dogs and humans, studies on dogs have primarily focused on how a dog's biological characteristics, such as their weight, affect the age–activity relationship. To date, there is little knowledge about how this relationship may be associated with contextual- and owner-level characteristics. We leveraged a large and novel data set from the Dog Aging Project (DAP) to investigate the extent to which the age–activity relationship is associated with certain dog and owner characteristics, namely dog size, owner age, and the environment in which they live. Dogs are a unique model for aging research as they are exposed to similar social and environmental elements as humans but have a shorter life span, allowing researchers to observe their entire life course. We find that older dogs are less active than younger dogs; rural dogs are more active than suburban and urban dogs, especially at younger ages; and larger dogs are more active than smaller dogs. These findings are generally consistent with previous studies. However, a surprising finding is that older owners have more active dogs than younger owners. As one of the first studies to utilize the large survey data from the DAP, this study lays the foundation for future investigations to further understand and identify the biological, social, and environmental causes, as well as consequences, of aging.

ABSTRACT: Despite considerable research efforts, pancreatic cancer is associated with a dire prognosis and a 5-year survival rate of only 10%. Early symptoms of the disease are mostly nonspecific. The premise of improved survival through early detection is that more individuals will benefit from potentially curative treatment. Artificial intelligence (AI) methodology has emerged as a successful tool for risk stratification and identification in general health care. In response to the maturity of AI, Kenner Family Research Fund conducted the 2020 AI and Early Detection of Pancreatic Cancer Virtual Summit (www.pdac-virtualsummit.org) in conjunction with the American Pancreatic Association, with a focus on the potential of AI to advance early detection efforts in this disease. This comprehensive presummit article was prepared based on information provided by each of the interdisciplinary participants on one of the 5 following topics: Progress, Problems, and Prospects for Early Detection; AI and Machine Learning; AI and Pancreatic Cancer-Current Efforts; Collaborative Opportunities; and Moving Forward-Reflections from Government, Industry, and Advocacy. The outcome from the robust Summit conversations, to be presented in a future white paper, indicate that significant progress must be the result of strategic collaboration among investigators and institutions from multidisciplinary backgrounds, supported by committed funders.

Despite considerable research efforts, pancreatic cancer is associated with a dire prognosis and a 5-year survival rate of only 10%. Early symptoms of the disease are mostly nonspecific. The premise of improved survival through early detection is that more individuals will benefit from potentially curative treatment. Artificial intelligence (AI) methodology has emerged as a successful tool for risk stratification and identification in general health care. In response to the maturity of AI, Kenner Family Research Fund conducted the 2020 AI and Early Detection of Pancreatic Cancer Virtual Summit (www.pdac-virtualsummit.org) in conjunction with the American Pancreatic Association, with a focus on the potential of AI to advance early detection efforts in this disease. This comprehensive presummit article was prepared based on information provided by each of the interdisciplinary participants on one of the 5 following topics: Progress, Problems, and Prospects for Early Detection; AI and Machine Learning; AI and Pancreatic Cancer—Current Efforts; Collaborative Opportunities; and Moving Forward—Reflections from Government, Industry, and Advocacy. The outcome from the robust Summit conversations, to be presented in a future white paper, indicate that significant progress must be the result of strategic collaboration among investigators and institutions from multidisciplinary backgrounds, supported by committed funders.

Throughout their careers, social scientists must come up with compelling research topics, decide when and where to publish, and revise their manuscripts for publication. Despite the importance of these skills, they are seldom if ever addressed in the course of graduate training. Heavy emphasis is placed on conducting research, and other core activities such as teaching also receive attention, yet fundamental academic practices are left almost entirely in the shadows.Practicing Sociology brings together a range of leading sociologists to reflect on their work and demystify this tacit knowledge. In conversational and engaging essays, they provide practical guidance and hard-won wisdom for readers at any stage of their scholarly careers. The book's three sections explore the art of finding new research questions, best practices in publishing, and how to make the most out of the peer review process. Contributors' distinctive voices come through as they recount their frustrations and failures as well as the joys of the sociological craft. They provide a range of perspectives, underscoring that there is no one "right" way to practice sociology but a constellation of different approaches that together give the field its vitality.Practicing Sociology features a team of skilled scholars including Peter Bearman, Paul J. DiMaggio, Wendy Espeland, Marion Fourcade, Shamus Rahman Khan, Eric Klinenberg, Michèle Lamont, Jennifer Lee, Mignon Moore, Mario Small, Duncan Watts, and many more

Rigorously inventive and revelatory in its adventurousness, 1650–1850 opens a forum for the discussion, investigation, and analysis of the full range of long-eighteenth-century writing, thinking, and artistry. Combining fresh considerations of prominent authors and artists with searches for overlooked or offbeat elements of the Enlightenment legacy, 1650–1850 delivers a comprehensive but richly detailed rendering of the first days, the first principles, and the first efforts of modern culture. Its pages open to the works of all nations and language traditions, providing a truly global picture of a period that routinely shattered boundaries. Volume 27 of this long-running journal is no exception to this tradition of focused inclusivity. Readers will travel through a blockbuster special feature on the topic of worldmaking and other worlds—on the Enlightenment zest for the discovery, charting, imagining, and evaluating of new worlds, envisioned worlds, utopian worlds, and worlds of the future. Essays in this enthusiastically extraterritorial offering escort readers through the science-fictional worlds of Lady Cavendish, around European gardens, over the high seas, across the American frontiers, into forests and exotic ecosystems, and, in sum, into the unlimited expanses of the Enlightenment mind. Further enlivening the volume is a cavalcade of full-length book reviews evaluating the latest in eighteenth-century scholarship

Frontmatter -- Índice -- Fútbol y sociedad en América Latina: a manera de introducción -- FÚTBOL, HISTORIA, SOCIEDAD -- Contar la historia del fútbol en América Latina -- Construyendo el campo sociológico del fútbol en América Latina -- PRIMERA PARTE IDENTIDADES Y ESTILOS -- Introducción -- La invención del fútbol latinoamericano: cinco relatos y un silencio -- Narrativas do estilo: uma história das fronteiras nacionais pelo futebol -- Verdeamarelismo na ponta das chuteiras: reconfiguração da identidade nacional brasileira e Golpe de Estado (2013-2018) -- La orureñidad en el fútbol, del campamento minero a la diáspora: colectividades nómadas e identidades migratorias -- SEGUNDA PARTE FUTBOLISTAS E HINCHADAS -- Introducción -- Campeonatos de fútbol y ecuavoley en Reuterpark-Haus der Jugend (Bonn). Redes transnacionales y prácticas de ciudadanía de migrantes latinoamericanos a través de la apropiación informal del espacio público -- Experiencias itinerantes: territorios, fronteras y disputas de una barra argentina en movimiento -- Ritos, identidades y colonialismo en hinchadas transnacionales en Colombia y México -- Fútbol globalizado: nuevas identidades y formas de asociación. Un análisis de los hinchas del F. C. Barcelona y del Real Madrid en Lima -- TERCERA PARTE. PODER POLÍTICO -- Introducción -- Fútbol y política/política y fútbol: aspectos históricos de unas relaciones peligrosas -- #VamosColombia: selección, nación y Twitter. El uso de Twitter para el nacionalismo deportivo del presidente Juan Manuel Santos -- Polític as e formas de torcer: novas faces do associativismo torcedor no Brasil -- Goles y cárteles de la droga: la influencia de estructuras criminales en el fútbol de América Latina -- CUARTA PARTE. DESIGUALDAD DE GÉNERO -- Introducción -- #Déjala trabajar: el fútbol y el feminismo en Brasil -- Aproximaciones al desarrollo del fútbol practicado por mujeres en Colombia -- Estrategias transculturales y de género en el fútbol de migrantes andinos en Brasil -- A "guerra dos sex os" nos Jogos Olímpicos 2016 -- QUINTA PARTE. Patrimonio cultural e indigenización -- Introducción -- Entre un pasado lejano y el presente: supervivencias de un juego de pelota mesoamericano -- The evolution of the mesoamerican ballgames through time -- El duelo entre la Escuela-Ayllu de W arisata y los vecinos de Achacachi: la indigenización del fútbol en el departamento de La Paz (1900-1940) -- Pelota mixteca: pertenencia, convivencia y ancestralidad -- SEXTA PARTE. LOS MEDIOS DE COMUNICACIÓN -- Introducción -- Cien años de goledad: medios, literatura y fútbol globalizado -- Cómo leer los clásicos… de fútbol -- Entre la naturalización y la visibilización: fútbol, racismo y prensa en Perú. Discurso sobre el racismo de la prensa escrita deportiva peruana a través del caso Tinga -- Brasil, Alema nha e Futebol: confrontos, mediações e multiculturalismo no jornalismo internacional -- SÉPTIMA PARTE. REPRESENTACIONES EN LITERATURA Y CINE -- Introducción -- La múltiple instrumentalización del fútbol -- Radiografía del potrero: Borocotó y los orígenes de la ficción de fútbol en Argentina -- Marcaje al hombre: fútbol y cine en la Venezuela del siglo XXI -- "Geraldinos": cultura popular e e xclusão social no novo Maracanã (Rio de Janeiro) -- Sobre las autoras, los autores, la editora y los editores