Suchergebnisse

The focus of this article was employment creation by developing forest park tourism industries in China. Analysis of the statistical data and an input—output approach showed that 1 direct job opportunity in tourism industries created 1.15 other job opportunities. In the high, middle, and low scenarios, the total predicted employment in forest park tourism was 8.14, 5.13, and 4.82 million, respectively, from 2011 to 2020. These results demonstrate the importance of considering employment within forest park tourism as a viable option.

Internet of Things (IoT) is increasingly common in our society and daily life, with applications ranging from personal devices (e.g., wearable devices such as Google Smartwatches) to smart home (e.g., smart TVs and Amazon Echo) to smart city/grid (e.g., unmanned aerial and/or ground vehicles), as well as in battlefield settings (e.g., Internet of Battlefield / Military Things). One corresponding trend associated with the increase in IoT devices, in terms of both number and diversity, is a significant increase in the volume, velocity, variety, variability, and value of the generated and resultant data (i.e., 5Vs of big data). ; Non peer reviewed

Yan-Hua Zheng,1 Yue-Yun Ma,2 Yi Ding,3 Xie-Qun Chen,1 Guang-Xun Gao1 1Department of Hematology, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China; 2Department of Clinical Laboratory Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China; 3Department of Pharmacy, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China Abstract: Invasive fungal infections especially in immunocompromised patients represent a dominating cause of mortality. The most commonly used antifungal agents can be divided into three broad categories, including triazoles, echinocandins and polyenes. Antifungal resistance is on the increase, posing a growing threat to the stewardship of immunocompromised patients with fungal infections. The paucity of currently available antifungals leads to the rapid emergence of drug resistance and thus aggravates the refractoriness of invasive fungal infections. Therefore, deep exploration into mechanisms of drug resistance and search for new antifungal targets are required. This review highlights the therapeutic strategies targeting Hsp90, calcineurin, trehalose biosynthesis and sphingolipids biosynthesis, in an attempt to provide clinical evidence for overcoming drug resistance and to form the rationale for combination therapy of conventional antifungals and agents with novel mechanisms of action. What's more, this review also gives a concise introduction of three new-fashioned antifungals, including carboxymethyl chitosan, silver nanoparticles and chromogranin A-N46. Keywords: carboxymethyl chitosan, chromogranin A-N46, Hsp90, calcineurin, trehalose, sphingolipids

Chronic fatigue syndrome (CFS) is a relatively new condition of unknown etiology. Research suggests that psychosocial factors such as perceived social support, life stress, and acculturation may significantly influence individuals who are prone to CFS. For 57 Chinese American individuals initially diagnosed with CFS, those who recovered after one year reported lower levels of life stress than those who did not recover. Effects of changes in perceived social support also appeared to be mediated by life stress.

Abstract
Background
Management of pharmaceuticals and personal care products (PPCPs) in the environment has become a social issue. In the present study, concentrations of 140 PPCPs at 20 sites in Baiyangdian Lake and Tai Lake from 2016 to 2017 were analyzed by ultra performance liquid chromatography mass spectrometer (UPLC–MS). Risk quotients (RQ) were calculated for each detected chemical at all sites and prioritization indices (PI), based on maximum RQ, were calculated. To assess the risk of chemicals that identified high priority (PI > 1), a more accurate method of joint probability curves (JPCs) was applied.

Results
A total of 42 PPCPs were identified and quantified detected in the two lakes, with maximum concentrations ranging from 0.04 to 889 ng/L. Among these, seven PPCPs were identified as high or moderate-risk pollutants for at least one site, 3 in Tai Lake and 5 in Baiyangdian Lake. Carbamazepine posed significant ecological risk at all 20 sites, such that more attention should be paid to that drug. Based on results of the JPCs, sulfamethoxazole, caffeine, diethyltoluamide, and carbamazepine were categorized as high or intermediate risks.

Conclusion
Occurrences and distributions of PPCPs were different in the two lakes. Multiple-level risk assessment from simple to more complex was appropriate in chemical risk management.