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Mexico's migratory laws outline a robust framework for refugee integration, but there are challenges with fulfilling the legal mandates. One primary challenge is a lack of institutional support for improving refugee integration at the federal, state, and municipal levels of government. In particular, financial resources and personnel have not kept pace with the increasing number of refugee applications, leaving COMAR without the capacity to fully address the current situation. To fill the gaps, civil society actors have stepped in, but their efforts cannot substitute for developing long-term institutional capacity. In addition to large-scale structural barriers, refugees face challenges in attempting to access employment, healthcare, and education. These challenges include but are not limited to low wages, informality, job market saturation, difficulty accessing financial institutions, burdensome bureaucracy, and a general lack of information about rights and procedures. This combination of challenges complicates refugees' integration into Mexican society. ; Public Affairs

In April of 2015, a 7.6 magnitude earthquake struck the Kathmandu Valley at the center of Nepal. Within the following year, Kathmandu was struck by a 7.3 magnitude earthquake and multiple aftershocks. The initial earthquake caused the deaths of 8,856 people, injured 22,309, and affected eight million more. Many agencies around the world came together to fund reconstruction efforts as part of a Nepal and a Multi-Donor Trust Fund (MDTF). The MDTF conducted an Earthquake Housing Damage and Characteristics Survey (EHDC) which led to the creation of Nepal Rural Housing Reconstruction Program (NRHRP), which sought to reconstruct earthquake-resistant homes. The NRHRP developed a homeowner-driven grant process and established the National Reconstruction Authority (NRA) to distribute housing reconstruction grants to families. Those grants were to be paid out via three tranches, each after the completion of a specific construction phase. During 2017, an international collaborative effort began among four parties: Hiroshima University (HU); Tribhuvan University (TU); Nepal's Alternative Energy Promotion Center (AEPC); and the Lyndon B. Johnson School of Public Affairs (LBJ) of the University of Texas at Austin (UT). The team investigated the challenges and opportunities for reconstruction of homes in rural areas damaged by the 2015 earthquake in and around the hinterland of Kathmandu Valley, Nepal. Within the context of a university course, students began by studying alternative building technologies (ABTs) being implemented in Nepal by local nongovernmental organizations (NGOs). When project members visited Nepal in March 2017, they interviewed rural residents to identify barriers to home reconstruction. During a field study, the students also met with local governmental officials and NGO representatives. This report describes students' field investigation in Nepal, background research on alternative building technologies (ABTs) for home reconstruction, and recommendations developed from consultation with stakeholders and technical advisors. The first chapter starts with the earthquake and its associated damage and describes the response of the Government of Nepal (GON) and the international community in forming the MDTF, the NRHRP, and the NRA. The second chapter discusses different alternative building technologies (ABTs) considered by the GON, including bamboo, hempcrete, rammed earth, Compressed Stabilized Earth Brick (CSEB), earthbags, and modified conventional housing. Each section describes the type of building style, its construction, materials and labor required, estimates of construction time (if available), costs, and a brief section on comparative advantages and disadvantages. The third chapter describes the 2017 field study in Nepal, included the locations of the field study and interviews and discussions with local NGOs, the governmental agencies, and local residents. The research group sought to learn whether a lack of affordable and appropriate building methods could explain why many villagers still live in temporary shelters. Village residents discussed barriers to housing reconstruction unrelated to the type of home being built. The final chapter presents conclusions from 2017 field study observations of the three villages. Researchers found four common barriers to reconstruction: the cost of transportation and materials; insufficient reconstruction incentives; grant processes with many procedural barriers to funding; and the need for consistent interaction of the community with governmental agencies. One suggestion is to evaluate the home reconstruction program to assess its procedures and outcomes. A second suggestion is for Nepal to enhance the number and authority of mobile teams of professionals to assist villagers seeking to reconstruct homes. ; Public Affairs

International audience ; The susceptibility of sheep to scrapie is under the control of the host's prion protein (PrP) gene and is also influenced by the strain of the agent. PrP polymorphisms at codons 136 (A/V), 154 (R/H) and 171 (Q/R/H) are the main determinants of susceptibility/resistance of sheep to classical scrapie. They are combined in four main variants of the wild-type ARQ allele: VRQ, AHQ, ARH and ARR. Breeding programmes have been undertaken on this basis in the European Union and the USA to increase the frequency of the resistant ARR allele in sheep populations. Herein, we report the results of a multi-flock study showing the protective effect of polymorphisms other than those at codons 136, 154 and 171 in Sarda breed sheep. All ARQ/ARQ affected sheep (n = 154) and 378 negative ARQ/ARQ controls from four scrapie outbreaks were submitted to sequencing of the PrP gene. The distribution of variations other than those at the standard three codons, between scrapie cases and negative controls, was statistically different in all flocks. In particular, the AT137RQ and ARQK176 alleles showed a clear protective effect. This is the first study demonstrating a protective influence of alleles other than ARR under field conditions. If further investigations in other sheep breeds and with other scrapie sources confirm these findings, the availability of various protective alleles in breeding programmes of sheep for scrapie resistance could be useful in breeds with a low frequency of the ARR allele and would allow maintaining a wider variability of the PrP gene.

International audience ; Scrapie in small ruminants belongs to transmissible spongiform encephalopathies (TSEs), or prion diseases, a family of fatal neurodegenerative disorders that affect humans and animals and can transmit within and between species by ingestion or inoculation. Conversion of the host-encoded prion protein (PrP), normal cellular PrP (PrPc), into a misfolded form, abnormal PrP (PrPSc), plays a key role in TSE transmission and pathogenesis. The intensified surveillance of scrapie in the European Union, together with the improvement of PrPSc detection techniques, has led to the discovery of a growing number of so-called atypical scrapie cases. These include clinical Nor98 cases first identified in Norwegian sheep on the basis of unusual pathological and PrPSc molecular features and ''cases'' that produced discordant responses in the rapid tests currently applied to the large-scale random screening of slaughtered or fallen animals. Worryingly, a substantial proportion of such cases involved sheep with PrP genotypes known until now to confer natural resistance to conventional scrapie. Here we report that both Nor98 and discordant cases, including three sheep homozygous for the resistant PrPARR allele (A136R154R171), efficiently transmitted the disease to transgenic mice expressing ovine PrP, and that they shared unique biological and biochemical features upon propagation in mice. These observations support the view that a truly infectious TSE agent, unrecognized until recently, infects sheep and goat flocks and may have important implications in terms of scrapie control and public health.

Scrapie in small ruminants belongs to transmissible spongiform encephalopathies (TSEs), or prion diseases, a family of fatal neurodegenerative disorders that affect humans and animals and can transmit within and between species by ingestion or inoculation. Conversion of the host-encoded prion protein (PrP), normal cellular PrP (PrPc), into a misfolded form, abnormal PrP (PrPSc), plays a key role in TSE transmission and pathogenesis. The intensified surveillance of scrapie in the European Union, together with the improvement of PrPSc detection techniques, has led to the discovery of a growing number of so-called atypical scrapie cases. These include clinical Nor98 cases first identified in Norwegian sheep on the basis of unusual pathological and PrPSc molecular features and "cases" that produced discordant responses in the rapid tests currently applied to the large-scale random screening of slaughtered or fallen animals. Worryingly, a substantial proportion of such cases involved sheep with PrP genotypes known until now to confer natural resistance to conventional scrapie. Here we report that both Nor98 and discordant cases, including three sheep homozygous for the resistant PrPARR allele (A136R154R171), efficiently transmitted the disease to transgenic mice expressing ovine PrP, and that they shared unique biological and biochemical features upon propagation in mice. These observations support the view that a truly infectious TSE agent, unrecognized until recently, infects sheep and goat flocks and may have important implications in terms of scrapie control and public health.

International audience ; Scrapie in small ruminants belongs to transmissible spongiform encephalopathies (TSEs), or prion diseases, a family of fatal neurodegenerative disorders that affect humans and animals and can transmit within and between species by ingestion or inoculation. Conversion of the host-encoded prion protein (PrP), normal cellular PrP (PrPc), into a misfolded form, abnormal PrP (PrPSc), plays a key role in TSE transmission and pathogenesis. The intensified surveillance of scrapie in the European Union, together with the improvement of PrPSc detection techniques, has led to the discovery of a growing number of so-called atypical scrapie cases. These include clinical Nor98 cases first identified in Norwegian sheep on the basis of unusual pathological and PrPSc molecular features and ''cases'' that produced discordant responses in the rapid tests currently applied to the large-scale random screening of slaughtered or fallen animals. Worryingly, a substantial proportion of such cases involved sheep with PrP genotypes known until now to confer natural resistance to conventional scrapie. Here we report that both Nor98 and discordant cases, including three sheep homozygous for the resistant PrPARR allele (A136R154R171), efficiently transmitted the disease to transgenic mice expressing ovine PrP, and that they shared unique biological and biochemical features upon propagation in mice. These observations support the view that a truly infectious TSE agent, unrecognized until recently, infects sheep and goat flocks and may have important implications in terms of scrapie control and public health.

International audience ; Scrapie in small ruminants belongs to transmissible spongiform encephalopathies (TSEs), or prion diseases, a family of fatal neurodegenerative disorders that affect humans and animals and can transmit within and between species by ingestion or inoculation. Conversion of the host-encoded prion protein (PrP), normal cellular PrP (PrPc), into a misfolded form, abnormal PrP (PrPSc), plays a key role in TSE transmission and pathogenesis. The intensified surveillance of scrapie in the European Union, together with the improvement of PrPSc detection techniques, has led to the discovery of a growing number of so-called atypical scrapie cases. These include clinical Nor98 cases first identified in Norwegian sheep on the basis of unusual pathological and PrPSc molecular features and ''cases'' that produced discordant responses in the rapid tests currently applied to the large-scale random screening of slaughtered or fallen animals. Worryingly, a substantial proportion of such cases involved sheep with PrP genotypes known until now to confer natural resistance to conventional scrapie. Here we report that both Nor98 and discordant cases, including three sheep homozygous for the resistant PrPARR allele (A136R154R171), efficiently transmitted the disease to transgenic mice expressing ovine PrP, and that they shared unique biological and biochemical features upon propagation in mice. These observations support the view that a truly infectious TSE agent, unrecognized until recently, infects sheep and goat flocks and may have important implications in terms of scrapie control and public health.

Scrapie in small ruminants belongs to transmissible spongiform encephalopathies (TSEs), or prion diseases, a family of fatal neurodegenerative disorders that affect humans and animals and can transmit within and between species by ingestion or inoculation. Conversion of the host-encoded prion protein (PrP), normal cellular PrP (PrPc), into a misfolded form, abnormal PrP (PrPSc), plays a key role in TSE transmission and pathogenesis. The intensified surveillance of scrapie in the European Union, together with the improvement of PrPSc detection techniques, has led to the discovery of a growing number of so-called atypical scrapie cases. These include clinical Nor98 cases first identified in Norwegian sheep on the basis of unusual pathological and PrPSc molecular features and ''cases'' that produced discordant responses in the rapid tests currently applied to the large-scale random screening of slaughtered or fallen animals. Worryingly, a substantial proportion of such cases involved sheep with PrP genotypes known until now to confer natural resistance to conventional scrapie. Here we report that both Nor98 and discordant cases, including three sheep homozygous for the resistant PrPARR allele (A136R154R171), efficiently transmitted the disease to transgenic mice expressing ovine PrP, and that they shared unique biological and biochemical features upon propagation in mice. These observations support the view that a truly infectious TSE agent, unrecognized until recently, infects sheep and goat flocks and may have important implications in terms of scrapie control and public health.

The Conjugate Gradient (CG) method is a powerful iterative approach for solving large-scale minimization problems, characterized by its simplicity, low computation cost and good convergence. In this paper, a new hybrid conjugate gradient HLB method (HLB: Hadji-Laskri-Bechouat) is proposed and analysed for unconstrained optimization. By comparing numerically CGHLB with PRP and RMIL+ and by using the Dolan and More CPU performance, we deduce that CGHLB is more efficient.
Keywords: Unconstrained optimization, hybrid conjugate gradient method, line search, descent property, global convergence.

AbstractThe purpose of this article is to find out and analyze the causes and policies of the Land Agency of Boyolali District for absentee farm ownership. This research is empirical. Methods of data collection using observation, interview, literature study and field study by finding out overlapping symptoms. Methods of data analysis using several stages ranging from data collection, data analysis and recent retrieval of conclusions. Prohibition of absentee ownership aims to improve the welfare of society, especially farmers. The prohibition of absentee ownership is stipulated in Law No. 56 Prp 1960, Government Regulation No. 224/1961, Government Regulation No. 41 of 1964. Implementation of this rule is less effective in Boyolali District, it is caused by several factors, namely: community factor, cultural factor , legal factors, facilities and infrastructure and economic factors. The provisions of existing absentee land rules are also deemed to be no longer appropriate to the present condition of society. Land Agency of Boyolali Regency as an institution authorized to make arrangements in this matter, said that juridically indeed the prohibition on absentee land ownership is present and still apply. But in the implementation of BPN Boyolali District classified as less active and no concrete actions are shown, because the Land Agency Boyolali still focus work on work plans / other activities that are considered more important, such as certified mass certified land certified. The policy has been done BPN Boyolali District is counseling and socialization about the prohibition of absentee land ownership. Orderly administration by BPN Boyolali District, namely by supervision of the transfer of rights of agricultural land through cooperation between related institutions namely Village Head, District and PPAT. In this regard BPN Boyolali will undertake a revamping of absentee land ownership in its territory, the adjustment of the absentee land ban arrangements that is adapted to the present conditions of society.Keywords: Agricultural Land; State Owned Right; Landreform; Absentee (Guntai)AbstrakTujuan ditulisnya artikel ini untuk mengetahui dan menganalisis penyebab terjadinya dan kebijakan Badan Pertanahan Kabupaten Boyolali atas kepemilikan tanah pertanian secara absentee. Penelitian ini bersifat empiris. Metode pengumpulan data menggunakan observasi, wawancara, studi pustaka dan studi lapangan dengan mencari tahu gejala tumpang tindih. Metode analisis data menggunakan beberapa tahapan mulai dari pengumpulan data, analisis data dan terakhir pengambilan simpulan. Larangan kepemilikan absentee bertujuan meningkatkan kesejahteraan masyarakat, terutama kaum petani. Larangan kepemilikan tamah absentee diatur dalam UU No 56 Prp Tahun 1960, Peraturan Pemerintah No 224 Tahun 1961, Peraturan Pemerintah Nomor 41 Tahun 1964. Pelaksanaannya aturan ini kurang berjalan efektif di Kabupaten Boyolali, hal tersebut disebabkan oleh beberapa faktor yaitu : faktor masyarakat, faktor budaya, faktor hukum, sarana dan prasarana dan faktor ekonomi. Ketentuan peraturan tanah absentee yang ada juga dipandang sudah tidak sesuai lagi dengan kondisi masyarakat sekarang. Badan Pertanahan Kabupaten Boyolali sebagai lembaga yang berwenang melakukan pengaturan dalam hal ini, mengatakan bahwa secara yuridis memang larangan mengenai kepemilikan tanah absentee ini ada dan masih berlaku. Namun dalam pelaksanaanya BPN Kabupaten Boyolali tergolong kurang aktif dan belum ada tindakan konkret yang ditunjukan, karena Badan Pertanahan Boyolali masih fokus mengerjakan rencana kerja/kegiatan lain yang dipandang lebih penting, misalnya penyertifikatan masal tanah yang berlum bersertifikat. Kebijakan yang dilakukan sudah BPN Kabupaten Boyolali adalah penyuluhan dan sosialisasi mengenai larangan kepemilikan tanah absentee. Tertib administrasi oleh BPN Kabupaten Boyolali, yaitu dengan pengawasan terhadap peralihan hak tanah pertanian melalui kerja sama antar instansi yang terkait yaitu Kepala Desa, Kecamatan dan PPAT. Berkaitan dengan hal ini BPN Boyolali akan melakukan pembenahan mengenai kepemilikan tanah absentee di wilayahnya, penyesuaian mengenai pengaturan larangan tanah absentee ini yang disesuaikan dengan kondisi masyarakat masa sekarang.Kata Kunci : Tanah Pertanian; Hak Menguasai Negara; Landreform; Absentee (Guntai)