Suchergebnisse

An increase in diphtheria cases in Sidoarjo District and there are cases with the status of being immunized against Diphtheria Pertussis Tetanus (DPT) indicate a problem with the immunization program. The success of immunization depends on the quality of the vaccine provided. DPT vaccine cold chain that is less can reduce the quality of the DPT vaccine. This study aims to analyze the closeness between DPT vaccine storage and recording of DPT vaccine cold chain and DPT vaccine cold chain quality at the Public health center (PHC) of Sidoarjo District. This research is a descriptive study with a cross-sectional research design. The sample size used is the total population, that is all PHC in Sidoarjo District are 26 PHC. The variables studied were storage, recording, and quality of DPT vaccine cold chain. The results showed that DPT vaccine storage was classified as good (58%), cold chain recording of DPT vaccine was lacking (77%) and the quality of the DPT vaccine cold chain in the PHC was classified as good (62%). The Spearman correlation test showed that the closeness between DPT vaccine storage and the quality of the DPT vaccine cold chain in the PHC was strong and positive (r=0.561). The closeness between the recording of the DPT vaccine cold chain with the quality of the DPT vaccine cold chain at the PHC was moderate and positive (r=0.421). The better DPT vaccine storage and DPT vaccine cold chain recording the better the quality of the DPT vaccine cold chain. It is necessary to improve the compliance of officers in terms of storing and recording cold chain DPT vaccines in PHC in accordance with procedures.

In the present study, clinical isolates of Bordetella pertussis collected in Poland from 1960 to 2005 were analyzed by pulsed-field gel electrophoresis (PFGE) according to protocols recommended in previous studies. Among the 110 isolates from 1995 to 2005, 59 PFGE patterns were found, most of which were different from those currently circulating in other European Union (EU) countries for which data are available. The PFGE patterns of currently disseminating B. pertussis clones were found within PFGE groups III and IV, as elsewhere in the EU, and in newly identified clusters A and C. Up to 70, 26, and 4%, respectively, of the currently isolated strains in Poland harbored ptxA1-prn1, ptxA1-prn2, and ptxA1-prn3 allele combinations, and most (82%) were found to be of the Fim2 phenotype. Differences in the extent of heterogeneity estimated by PFGE typing in B. pertussis populations circulating in Poland in comparison to other EU countries may be due to the different vaccine composition strategy, since routine pertussis vaccination was initiated in Poland in 1960.

Pertussis is a common vaccine-preventable disease (VPD) worldwide. Its reported incidence has increased steadily in the United States, where it is endemic. Tetanus is a rare but potentially fatal VPD. Foreign-born adults have lower tetanus–diphtheria–pertussis (Tdap) and tetanus–diphtheria (Td) vaccination coverage than do U.S.-born adults. We studied the association of migration-related, socio-demographic, and access-to-care factors with Tdap and Td vaccination among foreign-born adults living in the United States. The 2012 and 2013 National Health Interview Survey data for foreign-born respondents were analyzed. Multivariable logistic regression was conducted to calculate prevalence ratios and 95% confidence intervals, and to identify variables independently associated with Tdap and Td vaccination among foreign-born adults. Tdap and Td vaccination status was available for 9316 and 12,363 individuals, respectively. Overall vaccination coverage was 9.1% for Tdap and 49.8% for Td. Younger age, higher education, having private health insurance (vs. public insurance or uninsured), having visited a doctor in the previous year, and region of residence were independently associated with Tdap and Td vaccination. Among those reporting a doctor visit, two-thirds had not received Tdap. This study provides further evidence of the need to enhance access to health care and immunization services and reduce missed opportunities for Tdap and Td vaccination for foreign-born adults in the United States. These findings apply to all foreign-born, irrespective of their birthplace, citizenship, language and years of residence in the United States. Addressing vaccination disparities among the foreign-born will help achieve national vaccination goals and protect all communities in the United States.

The government held a diphtheria sub-national immunization week in 2012 to overcome the problem of diphtheria outbreaks in East Java Province. Bangkalan District is the district with the high incidence of diphtheria in East Java Province. This study aims to analyze the determinants of diphtheria events in Bangkalan District after the diphtheria sub-national immunization week in 2012. This study uses a case-control study design. Case samples were taken from a total of 31 cases, and control samples were taken as many as 124 people spread in 25 case villages and25 control villages. The bivariate analysis a using chi-square test and simple logistic regression. Multivariate analysis using logistic regression. The results showed that based on the results of bivariate analysis, individual and household levels related to diphtheria events, namely the status of Diphtheria Pertussis Tetanus (DPT) immunization, sub-national immunization week status, age and mother's education. Multivariate analysis showed that factors related to the diphtheria incidence in Bangkalan District after the 2012 diphtheria sub-national immunization week were DPT immunization (p = 0.012; OR= 4.765), incomplete DPT immunization (p = 0.001; OR = 6.276), age 3- 7 years (p = 0.014; OR = 15.137), ages 7-15 years (p = 0.001; OR = 41.984), and are not immunized at the time of sub-national immunization week (p = 0.020; OR = 3.553). The conclusion of this study is the DPT immunization status, age and status of diphtheria sub-national immunization week were the dominant factors affecting the incidence of diphtheria in Bangkalan District.

Background: The Victorian Government Department of Health funded a diphtheria, tetanus and acellular pertussis vaccine for parents of infants from June 2009 to June 2012 as part of a cocooning strategy for the control of pertussis. The aim of this study w

Background: Diphteria can be prevented by immunization of DPT-HB-Hib (Diphteria, Hepatitis B, dan Haemophillus Influenze B) to infants and DPT-HB-Hib Booster, DT (Diphteria Tetanus) and Td (Tetanus Diphteria) afterwards. In 2017, diphteria case rate in Surabaya was high, 29 cases, due to the lack of 7 dosages of diphteria immunization. Purpose: This study aimed to depict the completion history of diphteria immunization based on the completness of immunization status which suits to age groups of diphteria patients in Surabaya in 2017. Methods: This study was quantitave descriptive with study cross sectional design. The objects of this study were diphteria patients in Surabaya in 2017 (29 individuals). Data was collected by questionnaire and immunization record from KIA/KMS books which belongs to Government effort to control Citizen Health Development. The variables of this study was diphteria patients characteristics (age and gender) and the history diphteria immunization. Data were analyzed using univariate analysis with frequency table. Results: This study obtained that mostly the diphteria patients in Surabaya in 2017 suffered this disease in 18 until 84 months old (58.62%) and mostly happened to male (82.76%). All patients aged 18 months old received complete diphteria immunization (3.45%), but all patient aged more than ≥ 18 months old did not received complete diphteria immunization (96.55%). Mostly the patients did not receive re-immunization afterwards, i.e DPT-HB-Hib Booster, DT, and Td. Conclusion: The completion 7 dosages of diphteria immunization is important to diphteria cases, especially to diphteria re-immunization afterwards.