Suchergebnisse

By 1849, this book was in its fourth edition, having sold over 8,000 copies in less than eighteen months and making it one of the fastest-selling antislavery tracts of its time. The book's popularity can be attributed both to the strong voice of its author and Brown's notoriety as an abolitionist speaker. The son of a slave and a white man, Brown recounts his years in servitude, his cruel masters, and the brutal whippings he and those around him received. He details his failed attempt to escape with his mother; after their capture, they were sold to new masters. A subsequent escape attempt succeeds

"Through original case studies and analyses of real-life media experiences, Media Ethics challenges readers to think analytically and critically about ethical situations in mediated communication. This textbook provides a comprehensive introduction to the theoretical principles of ethical philosophies, facilitating awareness and critical reflection of ethical issues. In each chapter, the authors examine case studies spanning several continents and geopolitical and cultural contexts. To provide a framework for analyzing the cases and exploring the steps in moral reasoning, the book introduces the Potter Box, a powerful tool for moral analysis. Focusing on a wide range of ethical issues faced by media practitioners and news organizations, the cases in this new twelfth edition include the most prominent concerns in journalism, broadcasting, advertising, public relations, and entertainment today. It explores new topics such as the use of ChatGPT in newsrooms, the privacy implications of biometric technologies, the role of public relations in political campaigns, and advertisers' approach to sustainability and climate change. This core textbook is ideal for classes in media and communication ethics, journalism, public relations, advertising, entertainment media, and popular culture. Online Instructor and Student Resources including video introductions to each chapter, PowerPoint slides, sample discussion and exam questions and links to further resources are available at www.routledgelearning.com/mediaethics"--

"Democratic-leaning urban areas in states that otherwise lean Republican is an increasingly important phenomenon in American politics, one that will help shape elections and policy for decades to come. Blue Metros, Red States explores this phenomenon by analyzing demographic trends, voting patterns, economic data, and social characteristics of twenty-seven major metropolitan areas in thirteen swing states that will ultimately decide who is elected president and the party that controls each chamber of Congress. The book's key finding is a sharp split between different types of suburbs in swing states. Close-in suburbs that support denser mixed use projects and transit such as light rail mostly vote for Democrats. More distant suburbs that feature mainly large-lot, single-family detached houses and lack mass transit often vote for Republicans. The book locates the red/blue dividing line and assesses the electoral state of play in every swing state. This red/blue political line is rapidly shifting, however, as suburbs urbanize and grow more demographically diverse. Blue Metros, Red States is especially timely as the 2020 elections draw near"--

4, viii, 342 [i.e., 340], [2], lxxxix, [5] p., [1] folded leaf, [11] leaves of plates : ill., 3 maps ; 19 cm. (8vo) ; Dedicated to John Ellis. ; The second volume was not published. ; The "two whole sheet maps" of East and West Florida mentioned in the title were not issued with this work, but were eventually published separately in 1781. Cf. Library of Congress. Maps and charts of North America and the West Indies 1750-1789. Washington, 1981, p. 352. ; Most plates engraved by Romans. ; Error in paging: page numbers 176-177 omitted from pagination. ; "An aggregate and valuation of exports of produce from the province of Georgia . Compiled by William Brown, comptroller and searcher of His Majesty's Customs in the Port of Savannah."--folded table facing p. 104. ; "List of subscribers to this work."--p. i-viii. "A list of subscribers, whose names were too late to be prefixed to the work."--p. [344]. ; Errata, p. lxxxix and [xci-xcii].

PurposeThe purpose of this paper is to review "institutional experimentation" for protecting workers in response to the contraction of the standard employment relationship and the corresponding rise of "non-standard" forms of paid work.Design/methodology/approachThe paper draws on the existing research and knowledge base of the authors as well as a thorough review of the extant literature relating to: non-standard employment contracts; sources of labour supply engaging in non-standard work; exogenous pressures on the employment relationship; intermediaries that separate the management from the control of labour; and entities that subvert the employment relationship.FindingsPost-war industrial relations scholars characterised the traditional regulatory model of collective bargaining and the standard employment contract as a "web of rules". As work relations have become more market mediated, new institutional arrangements have developed to govern these relations and regulate the terms of engagement. The paper argues that these are indicative of an emergent "patchwork of rules" which are instructive for scholars, policymakers, workers' representatives and employers seeking solutions to the contraction of the traditional regulatory model.Research limitations/implicationsWhile the review of the institutional experimentation is potentially instructive for developing solutions to gaps in labour regulation, a drawback of this approach is that there are limits to the realisation of policy transfer. Some of the initiatives discussed in the paper may be more effective than others for protecting workers on non-standard contracts, but further research is necessary to test their effectiveness including in different contexts.Social implicationsThe findings indicate that a task ahead for the representatives of government, labour and business is to determine how to adapt the emergent patchwork of rules to protect workers from the new vulnerabilities created by, for example, employer extraction and exploitation of their individual bio data, social media data and, not far off, their personal genome sequence.Originality/valueThe paper addresses calls to examine the "institutional intersections" that have informed the changing ways that work is conducted and regulated. These intersections transcend international, national, sectoral and local units of analysis, as well as supply chains, fissured organisational dynamics, intermediaries and online platforms. The analysis also encompasses the broad range of stakeholders including businesses, labour and community groups, nongovernmental organisations and online communities that have influenced changing institutional approaches to employment protection.

Lead poisoning, mainly through incidental ingestion of lead ammunition in carcasses, is a threat to scavenging and predatory bird species worldwide. In Australia, shooting for animal control is widespread, and a range of native scavenging species are susceptible to lead exposure. However, the prevalence of lead exposure in Australia's scavenging and predatory birds is largely unknown. We evaluated the degree to which the Tasmanian wedge‐tailed eagle (Aquila audax fleayi), an endangered Australian raptor and facultative scavenger, showed evidence of lead exposure. We detected lead in 100% of femur and liver tissues of 109 eagle carcasses opportunistically collected throughout Tasmania between 1996 and 2018. Concentrations were elevated in 10% of 106 liver (>6 mg/kg dry wt) and 4% of 108 femur (>10 mg/kg dry wt) samples. We also detected lead in 96% of blood samples taken from 24 live nestlings, with 8% at elevated concentrations (>10 μg/dL). Of the liver samples with elevated lead, 73% had lead(207/206) isotope ratios within the published range of lead‐based bullets available in Tasmania. These first comprehensive data on lead exposure of an Australian raptor are comparable to those for raptor studies elsewhere that identify lead‐based ammunition exposure as a conservation threat. Our findings highlight the importance of further research and efforts to address lead contamination throughout the Tasmanian ecosystem and in other Australian regions. Environ Toxicol Chem 2021;40:219–230. © 2020 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals LLC on behalf of SETAC. This article has been contributed to by US Government employees and their work is in the public domain in the USA.

Each volume contains a certification statement and an errata statement, either tipped in or printed on the title page verso. ; Each volume has an index, and a list of the governors of Virginia for the period covered by the volume. ; Errors in paging: v. 1, p. 321, 346 misnumbered 323, 643; v. 2, page numbers 41 and 50 omitted; v. 4, p. 122, 320, 530 misnumbered 186, 203, 50; v. 5, p. 243, 306 misnumbered 234, 630; v. 6, p. 576 misnumbered 657; v. 7, p. 260 misnumbered 602, page numbers 535-536 omitted; v. 11, p. 182, 226, 295, 524 misnumbered 188, 225, 592, 542; v. 12, p. 423, 427, 657, 817, 831 misnumbered 224, 407, 665, 803, 183; v. 13, p. 436 misnumbered 336. ; Vol. 1: xxiv, 552, [1], xxvi-xxxii, 561-600 p.; v. 2: viii, [1], 10-612 [i.e., 610] p.; v. 3: [5], 10-612 p.; v. 4: 604 p.; v. 5: vi, [3], 10-568, [1], 574-603, [3] p.; v. 6: iv, [3], 10-604, [2] p.; v. 7: [7], 10-701 [i.e., 699], [1] p.; v. 8: 716, [2] p.; v. 9: v, [4], 10-656, [2] p.; v. 10: iv, [5], 10-663, [1] p.; v. 11: iv, [5]. 10-639, [1] p.; v. 12: [5], 10-832 p.; v. 13: [4], 649, [1] p. Last page of v. 6, 7, 8, 9, 10, 11, 13 blank. ; Imprint varies: v. 3: Philadelphia: Printed for the editor, by Thomas Desilver, no. 253, Market Street. 1823; v. 4: Richmond: Printed for the editor. At the Franklin Press.--W.W. Gray, printer, 1820; v. 5-6: Richmond: Printed for the editor, at the Franklin Press, W.W. Gray, print., 1819; v. 7: Richmond: Printed for the editor, at the Franklin Press, 1820; v. 8-9: Richmond: Printed for the editor, J. & G. Cochran, printers, 1821; v. 10: Richmond: Printed for the editor, by George Cochran. 1822; v. 11-12: Richmond: Printed for the editor, by George Cochran, 1823; v. 13: Philadelphia: Published for the editor, by Thomas Desilver, no. 253, Market Street. William Brown, printer. 1823. ; Publication was begun in 1809 and suspended after the appearance of v. 4 in 1814; resumed with an increased subscription by the state in 1819, and completed in 1823. A second edition of v. 1-4 was published, 1820-1823, to complete the set. See the "Preface to the second edition," v. 1, p. [xxiii]-xxiv, signed: William Waller Hening. Richmond, January 30th, 1823. ; Spine title: Hening's Statutes at large. ; Vol. 1-4 are the second edition, 1820-23. ; Shaw & Shoemaker ; Mode of access: Internet.

A collection of twenty of Frederick Douglass's most important orations This volume brings together twenty of Frederick Douglass's most historically significant speeches on a range of issues, including slavery, abolitionism, civil rights, sectionalism, temperance, women's rights, economic development, and immigration. Douglass's oratory is accompanied by speeches that he considered influential, his thoughts on giving public lectures and the skills necessary to succeed in that endeavor, commentary by his contemporaries on his performances, and modern-day assessments of Douglass's effectiveness as a public speaker and advocate

OBJECTIVES To explore the relevance of T-follicular-helper (Tfh) and pathogenic peripheral-helper T-cells (Tph) in promoting ectopic lymphoid structures (ELS) and B-cell mucosa-associated lymphoid tissue (MALT) lymphomas (MALT-L) in Sjögren's syndrome (SS) patients. METHODS Salivary gland (SG) biopsies with matched peripheral blood were collected from four centres across the European Union. Transcriptomic (microarray and quantitative PCR) analysis, FACS T-cell immunophenotyping with intracellular cytokine detection, multicolor immune-fluorescence microscopy and hybridisation were performed to characterise lesional and circulating Tfh and Tph-cells. SG-organ cultures were used to investigate functionally the blockade of T-cell costimulatory pathways on key proinflammatory cytokine production. RESULTS Transcriptomic analysis in SG identified Tfh-signature, interleukin-21 (IL-21) and the inducible T-cell co-stimulator (ICOS) costimulatory pathway as the most upregulated genes in ELS+SS patients, with parotid MALT-L displaying a 400-folds increase in IL-21 mRNA. Peripheral CD4CXC-motif chemokine receptor 5 (CXCR5)programmed cell death protein 1 (PD1)ICOS Tfh-like cells were significantly expanded in ELS+SS patients, were the main producers of IL-21, and closely correlated with circulating IgG and reduced complement C4. In the SG, lesional CD4CD45ROICOSPD1 cells selectively infiltrated ELS+ tissues and were aberrantly expanded in parotid MALT-L. In ELS+SG and MALT-L parotids, conventional CXCR5CD4PD1ICOSFoxp3 Tfh-cells and a uniquely expanded population of CXCR5CD4PD1ICOSFoxp3 Tph-cells displayed frequent IL-21/interferon-γ double-production but poor IL-17 expression. Finally, ICOS blockade in SG-organ cultures significantly reduced the production of IL-21 and inflammatory cytokines IL-6, IL-8 and tumour necrosis factor-α (TNF-α). CONCLUSIONS Overall, these findings highlight Tfh and Tph-cells, IL-21 and the ICOS costimulatory pathway as key pathogenic players in SS immunopathology and exploitable therapeutic targets in SS.

OBJECTIVES: To explore the relevance of T-follicular-helper (Tfh) and pathogenic peripheral-helper T-cells (Tph) in promoting ectopic lymphoid structures (ELS) and B-cell mucosa-associated lymphoid tissue (MALT) lymphomas (MALT-L) in Sjögren's syndrome (SS) patients. METHODS: Salivary gland (SG) biopsies with matched peripheral blood were collected from four centres across the European Union. Transcriptomic (microarray and quantitative PCR) analysis, FACS T-cell immunophenotyping with intracellular cytokine detection, multicolor immune-fluorescence microscopy and in situ hybridisation were performed to characterise lesional and circulating Tfh and Tph-cells. SG-organ cultures were used to investigate functionally the blockade of T-cell costimulatory pathways on key proinflammatory cytokine production. RESULTS: Transcriptomic analysis in SG identified Tfh-signature, interleukin-21 (IL-21) and the inducible T-cell co-stimulator (ICOS) costimulatory pathway as the most upregulated genes in ELS+SS patients, with parotid MALT-L displaying a 400-folds increase in IL-21 mRNA. Peripheral CD4(+)CXC-motif chemokine receptor 5 (CXCR5)(+)programmed cell death protein 1 (PD1)(+)ICOS(+) Tfh-like cells were significantly expanded in ELS+SS patients, were the main producers of IL-21, and closely correlated with circulating IgG and reduced complement C4. In the SG, lesional CD4(+)CD45RO(+)ICOS(+)PD1(+) cells selectively infiltrated ELS+ tissues and were aberrantly expanded in parotid MALT-L. In ELS+SG and MALT-L parotids, conventional CXCR5(+)CD4(+)PD1(+)ICOS(+)Foxp3(-) Tfh-cells and a uniquely expanded population of CXCR5(-)CD4(+)PD1(hi)ICOS(+)Foxp3(-) Tph-cells displayed frequent IL-21/interferon-γ double-production but poor IL-17 expression. Finally, ICOS blockade in ex vivo SG-organ cultures significantly reduced the production of IL-21 and inflammatory cytokines IL-6, IL-8 and tumour necrosis factor-α (TNF-α). CONCLUSIONS: Overall, these findings highlight Tfh and Tph-cells, IL-21 and the ICOS costimulatory pathway as key ...