Suchergebnisse

We report the discovery of a warm Neptune and a hot sub-Neptune transiting TOI-421 (BD-14 1137, TIC 94986319), a bright (V = 9.9) G9 dwarf star in a visual binary system observed by the Transiting Exoplanet Survey Satellite (TESS) space mission in Sectors 5 and 6. We performed ground-based follow-up observations-comprised of Las Cumbres Observatory Global Telescope transit photometry, NIRC2 adaptive optics imaging, and FIbre-fed Echelle Spectrograph, CORALIE, High Accuracy Radial velocity Planet Searcher, High Resolution echelle Spectrometer, and Planet Finder Spectrograph high-precision Doppler measurements-and confirmed the planetary nature of the 16 day transiting candidate announced by the TESS team. We discovered an additional radial velocity signal with a period of five days induced by the presence of a second planet in the system, which we also found to transit its host star. We found that the inner mini-Neptune, TOI-421 b, has an orbital period of P-b = 5.19672 +/- 0.00049 days, a mass of M-b = 7.17 +/- 0.66 M-circle plus, and a radius of R-b = R-circle plus, whereas the outer warm Neptune, TOI-421 c, has a period of P-c = 16.06819 +/- 0.00035 days, a mass of M-c = 16.42(-1.04)(+1.06)M(circle plus), a radius of R-c = 5.09(-0.15)(+0.16)R(circle plus), and a density of rho(c) = 0.685(-0.072)(+0.080) cm(-3). With its characteristics, the outer planet (rho(c) = 0.685(-0.0072)(+0.080) cm(-3)) is placed in the intriguing class of the super-puffy mini-Neptunes. TOI-421 b and TOI-421 c are found to be well-suited for atmospheric characterization. Our atmospheric simulations predict significant Ly alpha transit absorption, due to strong hydrogen escape in both planets, as well as the presence of detectable CH4 in the atmosphere of TOI-421 c if equilibrium chemistry is assumed. ; KESPRINT collaboration, an international consortium devoted to the characterization and research of exoplanets discovered with space-based missions NASA's Science Mission directorate NASA High-End Computing (HEC) Program through the NASA Advanced Supercomputing (NAS) Division at Ames Research Center National Aeronautics & Space Administration (NASA) European Research Council (ERC) 817540 European Research Council under the European Union's Horizon 2020 research and innovation program 832428 CRT foundation 2018.2323 Comision Nacional de Investigacion Cientifica y Tecnologica (CONICYT) CONICYT FONDECYT 3180246 Millennium Science Initiative, Chilean Ministry of Economy IC120009 Comision Nacional de Investigacion Cientifica y Tecnologica (CONICYT) CONICYT FONDECYT 1171208 Irish Research Council for Science, Engineering and Technology GOIPD/2018/659 Swedish National Space Agency DNR 65/19 136/13 Australian Research Council 170100521 NASA through Caltech/JPL grant RSA-1006130 NASA through TESS Guest Investigator Program 80NSSC19K1727 Alfred P. Sloan Foundation National Aeronautics & Space Administration (NASA) 80NSSC18K1585 80NSSC19K0379 National Science Foundation (NSF) AST1717000 Spanish Government RYC-2015-17697 FPI-SO from the Spanish Ministry of Economy and Competitiveness (MINECO) SEV-2015-0548-17-2 BES-2017-082610 National Aeronautics & Space Administration (NASA) NNX17AF27G HeisingSimons foundation PLATO grant GOLF CNES grant CONICYT-PFCHA/Doctorado Nacional, Chile 21140646 German Research Foundation (DFG) PA525/18-1 PA525/19-1 PA525/20-1 HA3279/12-1 RA714/14-1 National Aeronautics & Space Administration (NASA)

Frontmatter -- Contents -- Acknowledgments -- Introduction -- I Indigenous Society and Conquest -- Christopher Columbus ''Discovers'' Cuba -- The Devastation of the Indies -- Spanish Officials and Indigenous Resistance. Various Spanish Officials -- A World Destroyed -- ''Transculturation'' and Cuba -- Survival Stories -- II Sugar, Slavery, and Colonialism -- A Physician's Notes on Cuba -- The Death of the Forest -- Autobiography of a Slave -- Biography of a Runaway Slave -- Fleeing Slavery -- Santiago de Cuba's Fugitive Slaves -- Rumba -- The Trade in Chinese Laborers -- Life on a Coffee Plantation -- Cuba's First Railroad -- The Color Line -- Abolition! -- Cecilia Valdés -- Sab -- An Afro-Cuban Poet -- III The Struggle for Independence -- Freedom and Slavery -- Memories of a Cuban Girl -- José Martí's ''Our America'' -- Guantanamera -- The Explosion of the Maine. New York Journal -- U.S. Cartoonists Portray Cuba -- The Devastation of Counterinsurgency. Fifty-fifth Congress, Second Session -- IV Neocolonialism -- The Platt Amendment -- Imperialism and Sanitation -- A Child of the Platt Amendment -- Spain in Cuba -- The Independent Party of Color. El Partido Independiente de Color -- A Survivor -- Rachel's Song -- Honest Women -- Generals and Doctors -- A Crucial Decade -- Afrocubanismo and Son -- Drums in My Eyes -- Abakuá -- The First Wave of Cuban Feminism -- Life at the Mill -- Migrant Workers in the Sugar Industry -- The Cuban Counterpoint -- The Invasion of the Tourists -- Waiting Tables in Havana -- The Brothel of the Caribbean -- A Prostitute Remembers -- Sugarcane -- Where Is Cuba Headed? -- The Chase -- The Fall of Machado -- Sugar Mills and Soviets -- The United States Confronts the 1933 Revolution -- The Political Gangster -- The United Fruit Company in Cuba -- Cuba's Largest Inheritance. Bohemia -- The Last Call -- For Us, It Is Always the 26th of July -- Three Comandantes Talk It Over -- History Will Absolve Me -- Reminiscences of the Cuban Revolutionary War -- The United States Rules Cuba, 1952–1958 -- The Cuban Story in the New York Times -- V Building a New Society -- And Then Fidel Arrived -- Tornado -- Castro Announces the Revolution -- How the Poor Got More -- Fish à la Grande Jardinière -- Women in the Swamps -- Man and Socialism -- In the Fist of the Revolution -- The Agrarian Revolution -- 1961: The Year of Education -- The Literacy Campaign -- The ''Rehabilitation'' of Prostitutes -- The Family Code -- Homosexuality, Creativity, Dissidence -- The Original Sin -- Where the Island Sleeps Like a Wing -- Silence on Black Cuba -- Black Man in Red Cuba -- Post-modern Maroon in the Ultimate Palenque -- From Utopianism to Institutionalization -- Carlos Puebla Sings about the Economy -- VI Culture and Revolution -- Caliban -- For an Imperfect Cinema -- Dance and Social Change -- Revolutionary Sport -- Mea Cuba -- In Hard Times -- The Virgin of Charity of Cobre, Cuba's Patron Saint -- A Conversation on Santería and Palo Monte -- The Catholic Church and the Revolution -- Havana's Jewish Community -- VII The Cuban Revolution and the World -- The Venceremos Brigades -- The Cuban Revolution and the New Left -- The U.S. Government Responds to Revolution. Foreign Relations of the United States -- Castro Calls on Cubans to Resist the Counterrevolution -- Operation Mongoose -- Offensive Missiles on That Imprisoned Island -- Inconsolable Memories: A Cuban View of the Missile Crisis -- The Assassination Plots Select Committee to Study Governmental Operations with Respect to Intelligence Activities -- Cuban Refugee Children -- From Welcomed Exiles to Illegal Immigrants -- Wrong Channel -- We Came All the Way from Cuba So You Could Dress Like This? -- City on the Edge -- Singing for Nicaragua -- Cuban Medical Diplomacy -- VIII The ''Período Especial'' and the Future of the Revolution -- Silvio Rodríguez Sings of the Special Period -- From Communist Solidarity to Communist Solitary -- The Revolution Turns Forty -- Colonizing the Cuban Body -- Pope John Paul II Speaks in Cuba -- Emigration in the Special Period -- The Old Man and the Boy -- Civil Society -- Forty Years Later -- A Dissident Speaks Out -- One More Assassination Plot -- An Errand in Havana -- No Turning Back for Johnny -- Suggestions for Further Reading -- Acknowledgment of Copyrights -- Index

Importance: The increasing burden due to cancer and other noncommunicable diseases poses a threat to human development, which has resulted in global political commitments reflected in the Sustainable Development Goals as well as the World Health Organization (WHO) Global Action Plan on Non-Communicable Diseases. To determine if these commitments have resulted in improved cancer control, quantitative assessments of the cancer burden are required. Objective: To assess the burden for 29 cancer groups over time to provide a framework for policy discussion, resource allocation, and research focus. Evidence Review: Cancer incidence, mortality, years lived with disability, years of life lost, and disability-adjusted life-years (DALYs) were evaluated for 195 countries and territories by age and sex using the Global Burden of Disease study estimation methods. Levels and trends were analyzed over time, as well as by the Sociodemographic Index (SDI). Changes in incident cases were categorized by changes due to epidemiological vs demographic transition. Findings: In 2016, there were 17.2 million cancer cases worldwide and 8.9 million deaths. Cancer cases increased by 28% between 2006 and 2016. The smallest increase was seen in high SDI countries. Globally, population aging contributed 17%; population growth, 12%; and changes in age-specific rates, -1% to this change. The most common incident cancer globally for men was prostate cancer (1.4 million cases). The leading cause of cancer deaths and DALYs was tracheal, bronchus, and lung cancer (1.2 million deaths and 25.4 million DALYs). For women, the most common incident cancer and the leading cause of cancer deaths and DALYs was breast cancer (1.7 million incident cases, 535 000 deaths, and 14.9 million DALYs). In 2016, cancer caused 213.2 million DALYs globally for both sexes combined. Between 2006 and 2016, the average annual age-standardized incidence rates for all cancers combined increased in 130 of 195 countries or territories, and the average annual age-standardized death rates decreased within that timeframe in 143 of 195 countries or territories. Conclusions and Relevance: Large disparities exist between countries in cancer incidence, deaths, and associated disability. Scaling up cancer prevention and ensuring universal access to cancer care are required for health equity and to fulfill the global commitments for noncommunicable disease and cancer control.

Funder: Consejo Nacional de Ciencia y Tecnología (CONCYT); doi: https://doi.org/10.13039/501100007350 ; Funder: Research Foundation Flanders (FWO) postdoctoral fellowship ; Funder: The HSE University Basic Research Program ; Funder: JSPS KAKENHI Grant JP20K14222 ; Abstract: This N = 173,426 social science dataset was collected through the collaborative COVIDiSTRESS Global Survey – an open science effort to improve understanding of the human experiences of the 2020 COVID-19 pandemic between 30th March and 30th May, 2020. The dataset allows a cross-cultural study of psychological and behavioural responses to the Coronavirus pandemic and associated government measures like cancellation of public functions and stay at home orders implemented in many countries. The dataset contains demographic background variables as well as measures of Asian Disease Problem, perceived stress (PSS-10), availability of social provisions (SPS-10), trust in various authorities, trust in governmental measures to contain the virus (OECD trust), personality traits (BFF-15), information behaviours, agreement with the level of government intervention, and compliance with preventive measures, along with a rich pool of exploratory variables and written experiences. A global consortium from 39 countries and regions worked together to build and translate a survey with variables of shared interests, and recruited participants in 47 languages and dialects. Raw plus cleaned data and dynamic visualizations are available.

The COVIDiSTRESS global survey collects data on early human responses to the 2020 COVID-19 pandemic from 173 429 respondents in 48 countries. The open science study was co-designed by an international consortium of researchers to investigate how psychological responses differ across countries and cultures, and how this has impacted behaviour, coping and trust in government efforts to slow the spread of the virus. Starting in March 2020, COVIDiSTRESS leveraged the convenience of unpaid online recruitment to generate public data. The objective of the present analysis is to understand relationships between psychological responses in the early months of global coronavirus restrictions and help understand how different government measures succeed or fail in changing public behaviour. There were variations between and within countries. Although Western Europeans registered as more concerned over COVID-19, more stressed, and having slightly more trust in the governments' efforts, there was no clear geographical pattern in compliance with behavioural measures. Detailed plots illustrating between-countries differences are provided. Using both traditional and Bayesian analyses, we found that individuals who worried about getting sick worked harder to protect themselves and others. However, concern about the coronavirus itself did not account for all of the variances in experienced stress during the early months of COVID-19 restrictions. More alarmingly, such stress was associated with less compliance. Further, those most concerned over the coronavirus trusted in government measures primarily where policies were strict. While concern over a disease is a source of mental distress, other factors including strictness of protective measures, social support and personal lockdown conditions must also be taken into consideration to fully appreciate the psychological impact of COVID-19 and to understand why some people fail to follow behavioural guidelines intended to protect themselves and others from infection. The Stage 1 manuscript associated with this submission received in-principle acceptance (IPA) on 18 May 2020. Following IPA, the accepted Stage 1 version of the manuscript was preregistered on the Open Science Framework at https://osf.io/g2t3b. This preregistration was performed prior to data analysis. ; Peer reviewed

We present the temperature and polarization angular power spectra of the CMB measured by the Atacama Cosmology Telescope (ACT) from 5400 deg(2) of the 2013-2016 survey, which covers >15000 deg(2) at 98 and 150 GHz. For this analysis we adopt a blinding strategy to help avoid confirmation bias and, related to this, show numerous checks for systematic error done before unblinding. Using the likelihood for the cosmological analysis we constrain secondary sources of anisotropy and foreground emission, and derive a "CMB-only" spectrum that extends to l = 4000. At large angular scales, foreground emission at 150 GHz is similar to 1% of TT and EE within our selected regions and consistent with that found by Planck. Using the same likelihood, we obtain the cosmological parameters for Lambda CDM for the ACT data alone with a prior on the optical depth of tau = 0.065 +/- 0.015. Lambda CDM is a good fit. The best-fit model has a reduced chi(2) of 1.07 (PTE = 0.07) with H-0 = 67.9 +/- 1.5 km/s/Mpc. We show that the lensing BB signal is consistent with Lambda CDM and limit the celestial EB polarization angle to psi(P) = 0.07 degrees +/- 0.09 degrees. We directly cross correlate ACT with Planck and observe generally good agreement but with some discrepancies in TE. All data on which this analysis is based will be publicly released. ; National Science Foundation (NSF) AST0408698 AST-0965625 AST-1440226 PHY0355328 PHY-0855887 PHY-1214379 Princeton University University of Pennsylvania Canada Foundation for Innovation CFI under the Compute Canada Government of Ontario Ontario Research Fund \ Research Excellence University of Toronto Simons Foundation National Aeronautics & Space Administration (NASA) NNX13AE56G NNX14AB58G National Institute of Standards & Technology (NIST) - USA Cornell Presidential Postdoctoral Fellowship Comision Nacional de Investigacion Cientifica y Tecnologica (CONICYT) BASAL CATA AFB-170002 National Science Foundation (NSF) AST-1814971 AST1454881 AST-1513618 AST-1907657 AST-1910021 National Research Foundation - South Africa STFC Ernest Rutherford Fellowship ST/M004856/2 STFC Consolidated Grant ST/S00033X/1 Horizon 2020 ERC Starting Grant 849169 Dicke Fellowship Mishrahi and Wilkinson funds CIfAR's Gravity & the Extreme Universe Program CGIAR Dunlap Institute

BACKGROUND: A high circulating concentration of interleukin 6 is associated with increased risk of coronary heart disease. Blockade of the interleukin-6 receptor (IL6R) with a monoclonal antibody (tocilizumab) licensed for treatment of rheumatoid arthritis reduces systemic and articular inflammation. However, whether IL6R blockade also reduces risk of coronary heart disease is unknown. METHODS: Applying the mendelian randomisation principle, we used single nucleotide polymorphisms (SNPs) in the gene IL6R to evaluate the likely efficacy and safety of IL6R inhibition for primary prevention of coronary heart disease. We compared genetic findings with the effects of tocilizumab reported in randomised trials in patients with rheumatoid arthritis. FINDINGS: In 40 studies including up to 133,449 individuals, an IL6R SNP (rs7529229) marking a non-synonymous IL6R variant (rs8192284; p.Asp358Ala) was associated with increased circulating log interleukin-6 concentration (increase per allele 9·45%, 95% CI 8·34-10·57) as well as reduced C-reactive protein (decrease per allele 8·35%, 95% CI 7·31-9·38) and fibrinogen concentrations (decrease per allele 0·85%, 95% CI 0·60-1·10). This pattern of effects was consistent with IL6R blockade from infusions of tocilizumab (4-8 mg/kg every 4 weeks) in patients with rheumatoid arthritis studied in randomised trials. In 25,458 coronary heart disease cases and 100,740 controls, the IL6R rs7529229 SNP was associated with a decreased odds of coronary heart disease events (per allele odds ratio 0·95, 95% CI 0·93-0·97, p=1·53×10(-5)). INTERPRETATION: On the basis of genetic evidence in human beings, IL6R signalling seems to have a causal role in development of coronary heart disease. IL6R blockade could provide a novel therapeutic approach to prevention of coronary heart disease that warrants testing in suitably powered randomised trials. Genetic studies in populations could be used more widely to help to validate and prioritise novel drug targets or to repurpose existing agents and targets for new therapeutic uses. FUNDING: UK Medical Research Council; British Heart Foundation; Rosetrees Trust; US National Heart, Lung, and Blood Institute; Du Pont Pharma; Chest, Heart and Stroke Scotland; Wellcome Trust; Coronary Thrombosis Trust; Northwick Park Institute for Medical Research; UCLH/UCL Comprehensive Medical Research Centre; US National Institute on Aging; Academy of Finland; Netherlands Organisation for Health Research and Development; SANCO; Dutch Ministry of Public Health, Welfare and Sports; World Cancer Research Fund; Agentschap NL; European Commission; Swedish Heart-Lung Foundation; Swedish Research Council; Strategic Cardiovascular Programme of the Karolinska Institutet; Stockholm County Council; US National Institute of Neurological Disorders and Stroke; MedStar Health Research Institute; GlaxoSmithKline; Dutch Kidney Foundation; US National Institutes of Health; Netherlands Interuniversity Cardiology Institute of the Netherlands; Diabetes UK; European Union Seventh Framework Programme; National Institute for Healthy Ageing; Cancer Research UK; MacArthur Foundation.

Background: In the midst of the coronavirus pandemic, the International Chiropractors Association (ICA) posted reports claiming that chiropractic care can impact the immune system. These claims clash with recommendations from the World Health Organization and World Federation of Chiropractic. We discuss the scientific validity of the claims made in these ICA reports. Main body: We reviewed the two reports posted by the ICA on their website on March 20 and March 28, 2020. We explored the method used to develop the claim that chiropractic adjustments impact the immune system and discuss the scientific merit of that claim. We provide a response to the ICA reports and explain why this claim lacks scientific credibility and is dangerous to the public. More than 150 researchers from 11 countries reviewed and endorsed our response. Conclusion: In their reports, the ICA provided no valid clinical scientific evidence that chiropractic care can impact the immune system. We call on regulatory authorities and professional leaders to take robust political and regulatory action against those claiming that chiropractic adjustments have a clinical impact on the immune system.

Das International Social Survey Programme (ISSP) ist ein länderübergreifendes, fortlaufendes Umfrageprogramm, das jährlich Erhebungen zu Themen durchführt, die für die Sozialwissenschaften wichtig sind. Das Programm begann 1984 mit vier Gründungsmitgliedern - Australien, Deutschland, Großbritannien und den Vereinigten Staaten - und ist inzwischen auf fast 50 Mitgliedsländer aus aller Welt angewachsen. Da die Umfragen auf Replikationen ausgelegt sind, können die Daten sowohl für länder- als auch für zeitübergreifende Vergleiche genutzt werden. Jedes ISSP-Modul konzentriert sich auf ein bestimmtes Thema, das in regelmäßigen Zeitabständen wiederholt wird. Details zur Durchführung der nationalen ISSP-Umfragen entnehmen Sie bitte der Dokumentation. Die vorliegende Studie konzentriert sich auf Fragen zu Religion und religiöser Identität.

WOS: 000469975500005 ; We present the discovery of HD 221416 b, the first transiting planet identified by the Transiting Exoplanet Survey Satellite (TESS) for which asteroseismology of the host star is possible. HD 221416 b (HIP 116158, TOI-197) is a bright (V = 8.2 mag), spectroscopically classified subgiant that oscillates with an average frequency of about 430 mu Hz and displays a clear signature of mixed modes. The oscillation amplitude confirms that the redder TESS bandpass compared to Kepler has a small effect on the oscillations, supporting the expected yield of thousands of solar-like oscillators with TESS 2 minute cadence observations. Asteroseismic modeling yields a robust determination of the host star radius (R-* = 2.943 +/- 0.064 R-circle dot), mass (M-* = 1.212 +/- 0.074 M-circle dot), and age (4.9 +/- 1.1 Gyr), and demonstrates that it has just started ascending the red-giant branch. Combining asteroseismology with transit modeling and radial-velocity observations, we show that the planet is a "hot Saturn" (R-p = 9.17 +/- 0.33 R-circle plus) with an orbital period of similar to 14.3 days, irradiance of F = 343 +/- 24 F-circle plus, and moderate mass (M-p = 60.5 +/- 5.7 M-circle plus) and density (rho(p) = 0.431 +/- 0.062 g cm(-3)). The properties of HD 221416 b show that the host-star metallicity-planet mass correlation found in sub-Saturns (4-8 R-circle plus) does not extend to larger radii, indicating that planets in the transition between sub-Saturns and Jupiters follow a relatively narrow range of densities. With a density measured to similar to 15%, HD 221416 b is one of the best characterized Saturn-size planets to date, augmenting the small number of known transiting planets around evolved stars and demonstrating the power of TESS to characterize exoplanets and their host stars using asteroseismology. ; National Aeronautics and Space Administration through the TESS Guest Investigator Program [80NSSC18K1585]; National Science FoundationNational Science Foundation (NSF) [AST-1717000]; Science and Technology Facilities CouncilScience & Technology Facilities Council (STFC); UK Space Agency; European Social Fund via the Lithuanian Science Council [09.3.3-LMT-K-712-01-0103]; Danish National Research FoundationDanmarks Grundforskningsfond [DNRF106]; FONDECYT projectComision Nacional de Investigacion Cientifica y Tecnologica (CONICYT)CONICYT FONDECYT [1171208]; CONICYT projectComision Nacional de Investigacion Cientifica y Tecnologica (CONICYT) [BASAL AFB-170002]; Ministry for the Economy, Development, and Tourism's Programa Iniciativa Cientifica Milenio [IC 120009]; FONDECYTComision Nacional de Investigacion Cientifica y Tecnologica (CONICYT)CONICYT FONDECYT [3180246]; Millennium Institute of Astrophysics (MAS); MINECOSpanish Ministry of Economy & Competitiveness [ESP2017-82674-R]; AGAURAgencia de Gestio D'Ajuts Universitaris de Recerca Agaur (AGUAR) [SGR2017-1131]; PLATO grant from the CNES; European Research Council under the European Community's Seventh Framework Programme (FP72007-2013) ERC grant [338251]; European Research Council through the SPIRE grant [647383]; FCT (Portugal); FEDER through COMPETE2020 [UID/FIS/04434/2013, POCI-01-0145-FEDER-007672, PTDC/FIS-AST/30389/2017, POCI-01-0145-FEDER-030389]; European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grantEuropean Union (EU) [792848]; European UnionEuropean Union (EU) [664931]; Independent Research Fund Denmark [7027-00096B]; Australian Research CouncilAustralian Research Council; NASANational Aeronautics & Space Administration (NASA) [NNX16AI09G, AS5-26555]; NSFNational Science Foundation (NSF) [AST-1514676]; Australian Research CouncilAustralian Research Council [DP150100250]; ERCEuropean Research Council (ERC) [772293]; Ramon y Cajal fellowshipMinistry of Education and Science, Spain [RYC-2015-17697]; Carlsberg FoundationCarlsberg Foundation [CF17-0760]; HBCSE-NIUS programme; NASA through Hubble Fellowship grants - Space Telescope Science Institute [HST-HF2-51399.001, HST-HF2-51424.001]; Premiale 2015 MITiC; NKFIH [K-115709]; Lendulet Program of the Hungarian Academy of Sciences [LP2018-7/2018]; NASA's Science Mission directorate ; The authors wish to recognize and acknowledge the very significant cultural role and reverence that the summit of Maunakea has always had within the indigenous Hawai'ian community. We are most fortunate to have the opportunity to conduct observations from this mountain. We thank Andrei Tokovinin for helpful information on the Speckle observations obtained with SOAR. D.H. acknowledges support by the National Aeronautics and Space Administration through the TESS Guest Investigator Program (80NSSC18K1585) and by the National Science Foundation (AST-1717000). A.C. acknowledges support by the National Science Foundation under the Graduate Research Fellowship Program. W.J.C., W.H.B., A.M., O.J.H., and G.R.D. acknowledge support from the Science and Technology Facilities Council and UK Space Agency. H.K. and F.G. acknowledge support from the European Social Fund via the Lithuanian Science Council grant No. 09.3.3-LMT-K-712-01-0103. Funding for the Stellar Astrophysics Centre is provided by The Danish National Research Foundation (grant DNRF106). A.J. acknowledges support from FONDECYT project 1171208, CONICYT project BASAL AFB-170002, and by the Ministry for the Economy, Development, and Tourism's Programa Iniciativa Cientifica Milenio through grant IC 120009, awarded to the Millennium Institute of Astrophysics (MAS). R.B. acknowledges support from FONDECYT Post-doctoral Fellowship Project 3180246, and from the Millennium Institute of Astrophysics (MAS). A.M.S. is supported by grants ESP2017-82674-R (MINECO) and SGR2017-1131 (AGAUR). R.A.G. and L.B. acknowledge the support of the PLATO grant from the CNES. The research leading to the presented results has received funding from the European Research Council under the European Community's Seventh Framework Programme (FP72007-2013) ERC grant agreement No. 338251 (StellarAges). S.M. acknowledges support from the European Research Council through the SPIRE grant 647383. This work was also supported by FCT (Portugal) through national funds and by FEDER through COMPETE2020 by these grants: UID/FIS/04434/2013 and POCI-01-0145-FEDER-007672, PTDC/FIS-AST/30389/2017, and POCI-01-0145-FEDER-030389. T.L.C. acknowledges support from the European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No. 792848 (PULSATION). E.C. is funded by the European Union's Horizon 2020 research and innovation program under the Marie Sklodowska-Curie grant agreement No. 664931. V.S.A. acknowledges support from the Independent Research Fund Denmark (Research grant 7027-00096B). D.S. acknowledges support from the Australian Research Council. S.B. acknowledges NASA grant NNX16AI09G and NSF grant AST-1514676. T.R.W. acknowledges support from the Australian Research Council through grant DP150100250. A.M. acknowledges support from the ERC Consolidator Grant funding scheme (project ASTEROCHRONOMETRY, G.A. n. 772293). S.M. acknowledges support from the Ramon y Cajal fellowship number RYC-2015-17697. M.S.L. is supported by the Carlsberg Foundation (grant agreement No. CF17-0760). A.M. and P.R. acknowledge support from the HBCSE-NIUS programme. J.K.T. and J.T. acknowledge that support for this work was provided by NASA through Hubble Fellowship grants HST-HF2-51399.001 and HST-HF2-51424.001 awarded by the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., for NASA, under contract AS5-26555. T.S.R. acknowledges financial support from Premiale 2015 MITiC (PI B. Garilli).; This project has been supported by the NKFIH K-115709 grant and the Lendulet Program of the Hungarian Academy of Sciences, project No. LP2018-7/2018.; Based on observations made with the Hertzsprung SONG telescope operated on the Spanish Observatorio del Teide on the island of Tenerife by the Aarhus and Copenhagen Universities and by the Instituto de Astrofisica de Canarias. Funding for the TESS mission is provided by NASA's Science Mission directorate. We acknowledge the use of public TESS Alert data from pipelines at the TESS Science Office and at the TESS Science Processing Operations Center. This research has made use of the Exoplanet Follow-up Observation Program website, which is operated by the California Institute of Technology, under contract with the National Aeronautics and Space Administration under the Exoplanet Exploration Program. This paper includes data collected by the TESS mission, which are publicly available from the Mikulski Archive for Space Telescopes (MAST).

Importance The increasing burden due to cancer and other noncommunicable diseases poses a threat to human development, which has resulted in global political commitments reflected in the Sustainable Development Goals as well as the World Health Organization (WHO) Global Action Plan on Non-Communicable Diseases. To determine if these commitments have resulted in improved cancer control, quantitative assessments of the cancer burden are required. Objective To assess the burden for 29 cancer groups over time to provide a framework for policy discussion, resource allocation, and research focus. Evidence Review Cancer incidence, mortality, years lived with disability, years of life lost, and disability-adjusted life-years (DALYs) were evaluated for 195 countries and territories by age and sex using the Global Burden of Disease study estimation methods. Levels and trends were analyzed over time, as well as by the Sociodemographic Index (SDI). Changes in incident cases were categorized by changes due to epidemiological vs demographic transition. Findings In 2016, there were 17.2 million cancer cases worldwide and 8.9 million deaths. Cancer cases increased by 28% between 2006 and 2016. The smallest increase was seen in high SDI countries. Globally, population aging contributed 17%; population growth, 12%; and changes in age-specific rates, −1% to this change. The most common incident cancer globally for men was prostate cancer (1.4 million cases). The leading cause of cancer deaths and DALYs was tracheal, bronchus, and lung cancer (1.2 million deaths and 25.4 million DALYs). For women, the most common incident cancer and the leading cause of cancer deaths and DALYs was breast cancer (1.7 million incident cases, 535 000 deaths, and 14.9 million DALYs). In 2016, cancer caused 213.2 million DALYs globally for both sexes combined. Between 2006 and 2016, the average annual age-standardized incidence rates for all cancers combined increased in 130 of 195 countries or territories, and the average annual age-standardized death rates decreased within that timeframe in 143 of 195 countries or territories. Conclusions and Relevance Large disparities exist between countries in cancer incidence, deaths, and associated disability. Scaling up cancer prevention and ensuring universal access to cancer care are required for health equity and to fulfill the global commitments for noncommunicable disease and cancer control.

This book contains the abstracts of the papers/posters presented at the Tanzania Health Summit 2020 (THS-2020) Organized by the Ministry of Health Community Development, Gender, Elderly and Children (MoHCDGEC); President Office Regional Administration and Local Government (PORALG); Ministry of Health, Social Welfare, Elderly, Gender, and Children Zanzibar; Association of Private Health Facilities in Tanzania (APHFTA); National Muslim Council of Tanzania (BAKWATA); Christian Social Services Commission (CSSC); & Tindwa Medical and Health Services (TMHS) held on 25–26 November 2020. The Tanzania Health Summit is the annual largest healthcare platform in Tanzania that attracts more than 1000 participants, national and international experts, from policymakers, health researchers, public health professionals, health insurers, medical doctors, nurses, pharmacists, private health investors, supply chain experts, and the civil society. During the three-day summit, stakeholders and decision-makers from every field in healthcare work together to find solutions to the country's and regional health challenges and set the agenda for a healthier future. Summit Title: Tanzania Health SummitSummit Acronym: THS-2020Summit Date: 25–26 November 2020Summit Location: St. Gasper Hotel and Conference Centre in Dodoma, TanzaniaSummit Organizers: Ministry of Health Community Development, Gender, Elderly and Children (MoHCDGEC); President Office Regional Administration and Local Government (PORALG); Ministry of Health, Social Welfare, Elderly, Gender and Children Zanzibar; Association of Private Health Facilities in Tanzania (APHFTA); National Muslim Council of Tanzania (BAKWATA); Christian Social Services Commission (CSSC); & Tindwa Medical and Health Services (TMHS).

Frontmatter -- CONTENTS -- THE CONTRIBUTORS -- ACKNOWLEDGEMENTS -- TABLES AND FIGURES -- PREFACE -- 1 INTRODUCTION -- PART 1 ENERGY POLICY DELIVERY IN GENERAL -- 2 SIX MAXIMS FOR INFORMED ENERGY ANALYSIS AND POLICY -- 3 ENDING SUBSIDIES FOR FOSSIL FUEL EXPLORATION IN A WORLD OF UNBURNABLE CARBON -- 4 WERE NORTH SEA OIL AND GAS 'FIELD ALLOWANCES' SUBSIDIES - AND DOES IT MATTER? -- 5 RENEWABLE ENERGY DISPUTES -- 6 USING A LEGACY FRAME TO DELIVER ENERGY AND ENVIRONMENT POLICIES -- 7 THE EMERGENCE OF EU ENERGY LAW -- 8 HOW TO IMPROVE REGULATION -- 9 DELIVERING ENERGY NETWORKS SECURITY: ECONOMICS, REGULATION AND POLICY -- 10 THE ROLE OF MARKETING IN DELIVERING ENERGY LAW AND POLICY -- PART 2 ENERGY POLICY DELIVERY IN THE UNITED STATES -- 11 A BRIEF HISTORY OF US ENERGY POLICY -- 12 APPLYING INNOVATION POLICY TO THE US ENERGY/CLIMATE CHALLENGE -- 13 NATIONAL SCIENTIFIC LABORATORIES AS AN ENERGY POLICY VEHICLE: THE UNITED STATES' EXPERIENCE -- 14 DELIVERING ENERGY POLICY IN THE US: THE ROLE OF TAXES -- 15 DELIVERING THE WIND: DECONSTRUCTING RENEWABLE ENERGY SUCCESS IN TEXAS -- 16 SOLAR RIGHTS IN THE UNITED STATES -- 17 THE US-CHINA CLIMATE AGREEMENT: A NEW DIRECTION -- 18 GOING GREEN: THE UNITED STATES DEPARTMENT OF DEFENSE AND ENERGY SECURITY -- 19 US CONJUNCTIVE WATER MANAGEMENT AND SUSTAINABLE ENERGY DEVELOPMENT -- PART 3 ENERGY POLICY DELIVERY IN THE EUROPEAN UNION -- 20 DELIVERING NEW POLITY: PAVING THE WAY FOR THE EUROPEAN ENERGY UNION -- 21 ANTITRUST ENFORCEMENT IN THE EU ENERGY SECTOR -- 22 DELIVERING ENERGY POLICY IN THE EU: SOME THOUGHTS ON THE ROLE OF CONSUMERS -- 23 THE GROWING IMPACT OF FREE MOVEMENT PROVISIONS IN THE EU ENERGY MARKET -- 24 ENERGY, EXTERNALITIES AND THE NEED TO REVISIT DEUTSCHE BAHN: A PROPOSAL TO REVERSE THE EUROPEAN STANCE ON EU STATE AID LAW AND INTERNATIONAL AVIATION -- 25 RES: TOWARDS A NEW EUROPEAN POLICY -- 26 ENERGIEWENDE IN GERMANY: THE DAWN OF A NEW ENERGY ERA -- 27 WHAT IS A SUSTAINABLE POLICY? A CASE FOR THE ENERGIEWENDE -- 28 THE FINNISH ENERGY POLICY: FULFILLING THE EU ENERGY AND CLIMATE TARGETS WITH NUCLEAR AND RENEWABLES -- 29 THE EU-RUSSIA RELATIONSHIP AND THE EU ENERGY UNION: FROM DEPENDENCE AND VULNERABILITY TOWARDS COMPETITION AND A FREE FLOW -- PART 4 ELECTRICITY POLICY DELIVERY -- 30 THE ROLE OF UNCERTAINTY IN ENERGY INVESTMENTS AND REGULATION -- 31 ENERGY SECURITY IN AN UNPREDICTABLE WORLD: MAKING THE CASE AGAINST STATE AID LIMITATIONS IN ELECTRICITY GENERATION -- 32 DELIVERING A LOW-CARBON ELECTRICITY SYSTEM IN A LIBERALISED MARKET -- 33 A PROPOSAL FOR REFORMING AN ELECTRICITY MARKET FOR A LOW-CARBON ECONOMY -- 34 THE ROLE OF THE DEMAND SIDE IN ELECTRICITY -- 35 REPLACING FOSSIL FUEL GENERATION WITH RENEWABLE ELECTRICITY: IS MARKET INTEGRATION OR MARKET CIRCUMVENTION THE WAY FORWARD? -- 36 SUSCEPTIBILITY OF ELECTRICITY GENERATION TO CLIMATE VARIABILITY AND CHANGE IN EUROPE: A REVIEW OF LITERATURE -- 37 THE EXTERNAL DIMENSION OF CROSSBORDER ELECTRICITY TRANSMISSION PLANNING IN THE EU -- 38 INTEGRATING VEHICLES AND THE ELECTRICITY GRID TO STORE AND USE RENEWABLE ENERGY -- 39 A STITCH IN TIME: COULD IRELAND'S FORTHCOMING WHITE PAPER BREATHE NEW LIFE INTO ITS BRAVE BUT FALTERING RENEWABLE ELECTRICITY POLICY? -- 40 RECENT DEVELOPMENTS IN THE HUNGARIAN ELECTRICITY REGULATORY FRAMEWORK -- PART 5 NUCLEAR ENERGY -- 41 DELIVERING THE REVIVAL OF NUCLEAR POWER -- 42 ENERGY POLICY: THE ROLE OF NUCLEAR POWER -- 43 FINANCING NEW NUCLEAR POWER STATIONS -- 44 UK NUCLEAR NEW-BUILD PLANS IN THE LIGHT OF INTERNATIONAL EXPERIENCE -- 45 DELIVERING UK NUCLEAR POWER IN THE CONTEXT OF EUROPEAN ENERGY POLICY: THE CHALLENGES AHEAD -- 46 NUCLEAR LIABILITY: CURRENT ISSUES AND WORK IN PROGRESS FOR THE FUTURE -- 47 THE PRESENT STATUS OF NUCLEAR THIRD-PARTY LIABILITY AND NUCLEAR INSURANCE -- 48 SMALL MODULAR REACTORS: THE FUTURE OR THE SWANSONG OF THE NUCLEAR INDUSTRY? -- PART 6 RENEWABLE ENERGY -- 49 COHERENT PROMOTION OF RENEWABLES UNDER A CARBON EMISSIONS CAP -- 50 RENEWABLE ENERGY POLICIES CHANGE CARBON EMISSIONS EVEN UNDER EMISSIONS TRADING -- 51 THE RENEWABLE TRAJECTORY: AVOIDING THE TEMPTATION OF CHEAP OIL -- 52 IMPACT OF RENEWABLE PORTFOLIO STANDARDS ON IN-STATE RENEWABLE DEPLOYMENT IN THE US -- 53 RENEWABLE SUPPORT POLICIES IN EUROPE: EVALUATION OF THE PUSH-PULL FRAMEWORK FOR WIND AND PV IN THE EU -- 54 A VIEW FROM THE GLOBAL WIND INDUSTRY -- 55 THE NEW CONCEPT OF COMPETITIVE BIDDING ON PHOTOVOLTAIC IN THE GERMAN RENEWABLE ENERGY ACT 2014 -- 56 LEGAL CERTAINTY FOR GREEN ENERGY PROJECTS: SURE, BUT AT WHAT PRICE? -- 57 THE FUTURE OF HYDROELECTRIC POWER IN THE UNITED STATES: THINKING SMALL -- 58 HYDROPOWER: FROM PAST TO FUTURE UNCERTAINTIES -- 59 RENEWABLE ENERGY PRODUCTION IN MARINE AREAS AND COASTAL ZONE: THE NORWEGIAN MODEL -- 60 THE GEOPOLITICS OF CLEAN ENERGY: RE-ENGAGING WITH RUSSIA THROUGH RENEWABLE ENERGY COOPERATION -- PART 7 FOSSIL FUELS -- 61 TALKING ABOUT SHALE IN ANY LANGUAGE -- 62 THE SHALE REVOLUTION, FRACKING AND REGULATORY ACTIVITY IN THE US: A POLICY DIVIDED -- 63 FRACTURED SYSTEMS: A MULTIPLE POLICY PROPOSAL FOR PROMOTING SAFE SHALE GAS DELIVERY IN THE UNITED STATES -- 64 PREPARING PENNSYLVANIA FOR A POST-SHALE FUTURE -- 65 THE DECLINE OF COAL AND THE ECONOMIC TOLL ON THE APPALACHIAN REGION -- 66 THE EU NETWORK CODES AND PROSPECTS OF CROSS-BORDER NATURAL GAS PIPELINE PROJECTS -- 67 BUILDING THE ENERGY UNION: THE PROBLEM OF CROSS-BORDER GAS PIPELINE INTERCONNECTIONS IN BALTIC, CENTRAL AND SOUTHEASTERN EUROPE -- 68 EMINENT DOMAIN AUTHORITY FOR UPSTREAM GAS INFRASTRUCTURE: AN ALTERNATIVE APPROACH -- 69 PETROLEUM LICENSING ON THE UKCS FIFTY YEARS ON: PROBLEMS, SOLUTIONS AND MORE PROBLEMS? -- 70 GREENLAND OFFSHORE PETROLEUM REGULATION TOWARDS 'THE BLUE ARCTIC' -- PART 8 ENERGY JUSTICE -- 71 ENERGY JUSTICE: THE YIN AND YANG APPROACH -- 72 SUSTAINABLE DEVELOPMENT AND ENERGY JUSTICE: TWO AGENDAS COMBINED -- 73 ASSESSING THE JUSTICE IMPLICATIONS OF ENERGY INFRASTRUCTURAL DEVELOPMENT IN THE ARCTIC -- PART 9 ENERGY POVERTY AND HEALTH -- 74 ENERGY POVERTY AND AFFORDABLE SUSTAINABLE ENERGY TECHNOLOGIES (ASETS) -- 75 CHALLENGING ENERGY POVERTY POLICIES: INSIGHTS FROM SOUTH-EASTERN EUROPE -- 76 POLICY CHANGES FOR FUTUREPROOFING HOUSING STOCK -- 77 CHALLENGES FOR HEALTH SERVICES IN IDENTIFYING WHICH GROUPS ARE MOST VULNERABLE TO HEALTH IMPACTS OF COLD HOMES -- 78 ENERGY, LIFE, METABOLISM AND THE FOOD CHAIN -- PART 10 ENERGY EFFICIENCY AND DEMAND -- 79 ENERGY EFFICIENCY AND ENERGY DEMAND -- 80 ENERGY DEMAND REDUCTION POLICY -- 81 DEMAND RESPONSE IN WHOLESALE MARKETS -- 82 PERCEIVED EFFECTIVENESS OF DIFFERENT METHODS OF DELIVERING INFORMATION ON ENERGY EFFICIENCY -- 83 DEVELOPING BEHAVIOURAL INTERVENTIONS: THREE LESSONS LEARNED FOR DELIVERING ENERGY POLICY -- 84 POLICY MIXES IN STIMULATING ENERGY TRANSITIONS: THE CASE OF UK ENERGY EFFICIENCY POLICY -- 85 THE JOURNEY OF SMART METERING IN GREAT BRITAIN: A REVISIT -- 86 RETHINKING HOUSEHOLD ENERGY CONSUMPTION STRATEGIES: THE IMPORTANCE OF DEMAND AND EXPECTATIONS -- 87 FINANCIAL INCENTIVES FOR ENERGYEFFICIENT APPLIANCES -- PART 11 ENERGY SECURITY -- 88 ENERGY SECURITY AND ENERGY POLICY INCOHERENCE -- 89 DESIGNING INTERNATIONAL TRADE IN ENERGY GOVERNANCE FOR EU ENERGY SECURITY -- 90 NATO AND EUROPEAN ENERGY SECURITY -- 91 GENEALOGY OF THE CURRENT GAS SECURITY SITUATION IN THE EU-UKRAINE-RUSSIA ENERGY TRIANGLE AND THE ROLE OF INTERNATIONAL LAW -- PART 12 COUNTRY-SPECIFIC AND INTERNATIONAL ENERGY POLICY DELIVERY -- 92 GERMAN ENERGY LAW -- 93 DELIVERING ENERGY LAW AND POLICY IN MALTA -- 94 DELIVERING ENERGY EFFICIENCY POLICIES IN ROMANIA -- 95 ENERGY LAW IN THE CZECH REPUBLIC: 'UNBUNDLING' ČEZ -- 96 DELIVERING ENERGY POLICY REFORM IN UKRAINE: LEGAL ISSUES IN THE LIGHT OF EUROPEAN INTEGRATION -- 97 A SYSTEMIC APPROACH TO RENEWABLE ELECTRICITY TECHNOLOGY DEPLOYMENT: THE 'MISSING LINK' IN OPTIMISING POLICY DELIVERY IN THE UK? -- 98 DELIVERING ENERGY POLICY: IS THERE NEED FOR KEY CHANGES IN THE NEXT UK PARLIAMENTARY PERIOD? -- 99 ENERGY AND THE STATE IN THE MIDDLE EAST -- 100 DELIVERING ENERGY POLICY IN ARGENTINA -- 101 THE ARCTIC: SOURCE OF ENERGY? SOURCE OF CONFLICT? SOURCE OF POLICY INNOVATION -- PART 13 CITIES, COMMUNITY ENERGY AND PUBLIC ENGAGEMENT -- 102 DELIVERING ENERGY (OFTEN) REQUIRES PUBLIC

Das International Social Survey Programme (ISSP) ist ein länderübergreifendes, fortlaufendes Umfrageprogramm, das jährlich Erhebungen zu Themen durchführt, die für die Sozialwissenschaften wichtig sind. Das Programm begann 1984 mit vier Gründungsmitgliedern - Australien, Deutschland, Großbritannien und den Vereinigten Staaten - und ist inzwischen auf fast 50 Mitgliedsländer aus aller Welt angewachsen. Da die Umfragen auf Replikationen ausgelegt sind, können die Daten sowohl für länder- als auch für zeitübergreifende Vergleiche genutzt werden. Jedes ISSP-Modul konzentriert sich auf ein bestimmtes Thema, das in regelmäßigen Zeitabständen wiederholt wird. Details zur Durchführung der nationalen ISSP-Umfragen entnehmen Sie bitte der Dokumentation. Die vorliegende Studie konzentriert sich auf Fragen zu Umwelt, Klimawandel und Umweltschutz.

Das International Social Survey Programme (ISSP) ist ein länderübergreifendes, fortlaufendes Umfrageprogramm, das jährlich Erhebungen zu Themen durchführt, die für die Sozialwissenschaften wichtig sind. Das Programm begann 1984 mit vier Gründungsmitgliedern - Australien, Deutschland, Großbritannien und den Vereinigten Staaten - und ist inzwischen auf fast 50 Mitgliedsländer aus aller Welt angewachsen. Da die Umfragen auf Replikationen ausgelegt sind, können die Daten sowohl für länder- als auch für zeitübergreifende Vergleiche genutzt werden. Jedes ISSP-Modul konzentriert sich auf ein bestimmtes Thema, das in regelmäßigen Zeitabständen wiederholt wird. Details zur Durchführung der nationalen ISSP-Umfragen entnehmen Sie bitte der Dokumentation. Die vorliegende Studie konzentriert sich auf Fragen zu sozialer Ungleichheit.