Thesis2020

Bacillus subtilis biofilm formation under extreme terrestrial and simulated extraterrestrial conditions

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Abstract

Since the Apollo 16 mission in 1972, Bacillus subtilis served as bacterial model organism in space. Due to the ability to form highly resistant endospores and complex biofilms, it was used to investigate the effects of unshielded space radiation as well as the limits of life in space. Within the International Space Station (ISS), fungal and bacterial biofilms already emerged as a burden that could harm the spacecraft due to material corrosion as well as the crew by causing infections. The ISS is a sensitive environment in which biofilm associated clogging or contaminating of life-support sy...

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