Open Access BASE2018

Outbreak of Tuberculosis and Multidrug-Resistant Tuberculosis, Mbuji-Mayi Central Prison, Democratic Republic of the Congo

Kayomo, Michel Kaswa; Hasker, Epco; Aloni, Muriel; Nkuku, Léontine; Kazadi, Marcel; Kabengele, Thierry; Muteteke, Dorcas; Kapita, François; Lufulwabo, Alphonse; Mukadi, Ya Diul; Muyembe-Tamfum, Jean-Jacques; Ieven, Margareta; de Jong, Bouke C; Boelaert, Marleen

Open Access

Abstract

After an alert regarding ≈31 tuberculosis (TB) cases, 3 of which were rifampin-resistant TB cases, in Mbuji-Mayi Central Prison, Democratic Republic of the Congo, we conducted an outbreak investigation in January 2015. We analyzed sputum of presumptive TB patients by using the Xpert MTB/RIF assay. We also assessed the Mycobacterium tuberculosis isolates' drug-susceptibility patterns and risk factors for TB infection. Among a prison population of 918 inmates, 29 TB case-patients were already undergoing treatment. We found an additional 475 presumptive TB case-patients and confirmed TB in 170 of them. In March 2015, the prevalence rate of confirmed TB was 21.7% (199/918 inmates). We detected an additional 14 cases of rifampin-resistant TB and initiated treatment in all 14 of these case-patients. Overcrowded living conditions and poor nutrition appeared to be the driving factors behind the high TB incidence in this prison.

Subjects

Research

Languages

English

Publisher

Centers for Disease Control and Prevention

DOI

10.3201/eid2411.180769

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