Role of Vehicles in Diagnosing Contact Allergy: An Update
In: Exogenous dermatology: physical, chemical, biological, Band 1, Heft 3, S. 107-111
ISSN: 1424-4624
In suspected allergic contact dermatitis, the proper choice of vehicles for patch testing may be critical. The role of vehicles in diagnostic patch testing has been summarized, suggesting that improved delivery systems might significantly increase the reproducibility and reliability of patch tests. We review the literature subsequent to 1992 for advances in our knowledge of the optimization of vehicles for patch testing. A universal vehicle more efficient than petrolatum or water remains elusive; in vitro percutaneous penetration data provide insight that questions standard dogma.