Time‐ and Loading‐Dependence in the McKone Model for Dermal Uptake of Organic Chemicals from a Soil Matrix

In: Risk analysis: an international journal, Band 11, Heft 3, S. 491-497

Abstract

McKone has recently proposed an innovative two‐layer model for dermal uptake of organic chemicals from a soil matrix that explicitly includes variables for properties of the chemical, the soil, the skin, and the exposure. In this note, we investigate the joint time‐ and loading‐dependencies implicit in the model by using MATHEMATICA to find and plot a closed‐form function for the uptake fraction for six aromatic hydrocarbons.